Tiyeni tiphunzire zambiri za hormone ya Leptin, yomwe imakuthandizani kulamulira kulemera kwanu.

Kodi munayamba mwadzifunsapo chifukwa chake timamva njala, momwe timamvera titadya, komanso chifukwa chake zimakhala zosavuta kwa ena kunenepa pomwe ena zimawavuta kuchepetsa thupi? Lero tikambirana za mankhwala opangidwa m'thupi mwathu omwe amalumikizidwa ndi zonsezi. Amatchedwa Leptin. Kunena zoona, leptin ndi mahomoni omwe amatulutsidwa ndi maselo athu amafuta (mafuta) omwe amatithandiza kusunga kulemera kwa thupi lathu kwa nthawi yayitali.

Kodi Leptin ndi chiyani? Tiyeni tione mwachidule.

Tangoganizani kuti mafuta m'thupi lanu amatulutsa mahomoni otchedwa Leptin. Chifukwa chake, ntchito yayikulu ya Leptin ndikulamulira njala yathu ndikutipatsa kumva kuti "ndakhuta, ndakhuta" (kukhuta) titadya. Zili ngati kasamalidwe kakang'ono komwe kamayang'anira kulemera kwa thupi lathu.

Asayansi adapeza mahomoni otchedwa leptin mu 1994. Izi zikutanthauza kuti pali zambiri zoti apeze zokhudza mahomoniwa. Akufufuza kale ngati leptin ingagwiritsidwe ntchito pochiza matenda ochepetsa thupi, matenda a Alzheimer's, thanzi la kubereka, komanso kusabereka.

"Ah... ngati leptin imayang'anira kulemera, kodi ifenso sitingathe kulamulira leptin?" mungaganize choncho. Koma zoona zake n'zakuti, homoni iyi si yosavuta kuilamulira monga momwe timafunira.

Kodi leptin imagwira ntchito bwanji m'thupi lathu?

Ntchito yaikulu ya Leptin ndi kuthandiza kuti thupi lathu likhale lolimba. Makamaka, zimathandiza kuti thupi lathu likhale logwirizana kwa nthawi yayitali pakati pa kuchuluka kwa chakudya chomwe timadya ndi momwe thupi lathu limagwiritsira ntchito mphamvu. Izi zikutanthauza kuti, zimathandiza kuti tisamve njala pamene thupi lathu silikufuna mphamvu (ma calories).

Leptin imagwira ntchito makamaka pa hypothalamus, gawo la ubongo wathu lomwe limayang'anira njala yathu ndi mphamvu zathu. Komabe, ma receptors omwe amakhudzidwa ndi leptin amapezekanso m'zigawo zina za thupi lathu.

Koma apa pali chinthu choti mumvetse. Leptin si hormone yomwe imatipangitsa kumva njala titadya chakudya chimodzi. M'malo mwake, imatithandiza kusunga kulemera kwathu mwa kusintha kuchuluka kwa chakudya chomwe timadya pakapita nthawi , kulamulira momwe timagwiritsira ntchito mphamvu, komanso kutithandiza kuwongolera kulemera kwathu.

Zotsatira za Leptin zimamveka makamaka mukamayesa kuchepetsa thupi. Taganizirani izi, mafuta m'thupi lanu akachepa, kuchuluka kwa leptin m'thupi lanu kumachepanso. Kenako ubongo umalandira chizindikiro choti, "O, thupi lilibe chakudya chokwanira, zimakhala ngati tikusala kudya." Ichi ndichifukwa chake nthawi zina mumamva njala kwambiri ndipo mumalakalaka zakudya zosiyanasiyana. Kenako mumayesedwa kudya kwambiri. Izi zingapangitse kuti kuchepetsa thupi kukhale kovuta kwambiri.

Asayansi akufufuzabe za Leptin. Akukhulupirira kuti Leptin imakhudzanso:

• Kagayidwe kachakudya
• Dongosolo la endocrine - ndiko kuti, dongosolo lathu la mahomoni
• Chitetezo chamthupi - dongosolo lomwe limateteza ku matenda

Kodi kuchuluka kwa leptin kumayendetsedwa bwanji?

Leptin imapangidwa ndikutulutsidwa ndi minofu yoyera yamafuta m'thupi lathu. Minofu yoyera yamafuta iyi ndiye mtundu waukulu wamafuta m'thupi lathu. Mwachidule, ndi mafuta omwe amasungidwa m'thupi lanu.

Popeza Leptin imapangidwa ndi maselo amafuta, kuchuluka kwa Leptin m'magazi mwanu kumagwirizana mwachindunji ndi kuchuluka kwa mafuta m'thupi mwanu. Izi zikutanthauza kuti, ngati muli ndi mafuta ochepa m'thupi, muli ndi Leptin yochepa. Ngati muli ndi mafuta ambiri m'thupi, muli ndi Leptin yambiri. N'zosavuta, eti?

Ngati mafuta m'thupi lanu akuwonjezeka pakapita nthawi, kuchuluka kwa leptin m'thupi lanu kudzawonjezeka. Mosiyana ndi zimenezi, ngati mafuta m'thupi lanu achepa, kuchuluka kwa leptin m'thupi lanu kudzachepa.

Kodi chimachitika ndi chiyani ngati leptin ikuwonjezeka?

Mlingo wa leptin nthawi zambiri umakhala wokwera kwa anthu onenepa kwambiri. Izi zimatchedwa hyperleptinemia. Ngati kuchuluka kwa leptin kuli kokwera nthawi zonse, ubongo wathu sungayankhe bwino ku leptin. Izi zimatchedwa kukana kwa leptin .

Pali zinthu zina zingapo zomwe zingagwirizane ndi hyperleptinemia:

• Kuvutika maganizo
• Kukonda kudya
• Matenda a neurodegenerative
• Matenda a chiwindi onenepa omwe si a mowa
• Matenda a Rabson-Mendenhall - Ichi ndi matenda osowa kwambiri a majini.

Kodi Kukana kwa Leptin ndi Chiyani?

Ngati muli ndi vuto la Leptin Resistance, ubongo wanu suyankha Leptin mwachibadwa. Tangoganizirani, Leptin ikupitiriza kutumiza uthenga ku ubongo kuti "Ndadya chakudya chokwanira, ndakhuta," koma ubongo sukuwoneka kuti ukusamala. Chifukwa chake, simukumva kukhuta. Chifukwa cha izi, mukupitiriza kudya, ngakhale muli ndi mafuta ambiri osungidwa m'thupi lanu.

Sikuti kokha, komanso chifukwa chakuti Leptin sikugwira ntchito bwino, ubongo umaganiza kuti thupi likusowa chakudya ndipo likusowa chakudya. Kenako, kuti tisunge mphamvu, ubongo umachepetsa mphamvu zathu, komanso umachepetsa kuchuluka kwa ma calories omwe timagwiritsa ntchito tikamapuma. Mwachidule, Basal Metabolic Rate (BMR) yathu imachepa.

Mukuona, kukana kwa leptin kumakupangitsani kumva njala nthawi zonse, komanso kumachepetsa BMR yanu. Zinthu ziwirizi zikagwirizana, kunenepa kumaipiraipira.

Asayansi pakadali pano akufufuza mankhwala omwe angachiritse kukana kwa leptin.

Kodi zizindikiro za Leptin Resistance ndi ziti?

Zizindikiro zazikulu za kusamva bwino kwa leptin ndikumva njala nthawi zonse (hyperphagia) komanso kudya mopitirira muyeso. Zizindikirozi zimachitika ngakhale mafuta ambiri atakhala m'thupi.

Komabe, pali zinthu zina ndi matenda omwe angayambitse zizindikirozi. Kukana kwa Leptin sikokhako. Popeza asayansi akuphunzirabe za leptin, n'zotheka kuti zizindikiro zina za kukana kwa leptin zidzapezeka mtsogolo.

Kodi chimachitika ndi chiyani ngati leptin yachepa?

Kusowa kwa Leptin ndi vuto losowa kwambiri. Matenda akuluakulu okhudzana ndi vutoli ndi kusowa kwa leptin kobadwa nako. Ili ndi vuto la majini lomwe limapezeka pobadwa. Anthu omwe ali ndi vutoli sapanga leptin kuchokera ku minofu yawo yamafuta.

Ngati leptin palibe, thupi limaganiza kuti palibe mafuta m'thupi. Izi zimapangitsa kuti munthu azimva njala yambiri komanso azilakalaka kudya. Pachifukwa ichi, ana omwe ali ndi vuto la leptin amabadwa ndi kunenepa kwambiri (kunenepa kwa kalasi III) ali aang'ono kwambiri, ndipo amatha msinkhu mochedwa.

Matenda ena omwe angagwirizane ndi vutoli:

• Dyslipidemia - kusalingana kwa mafuta monga cholesterol ndi triglycerides
• Matenda a chiwindi chamafuta
• Matenda opatsirana pafupipafupi a bakiteriya
• Hyperinsulinemia - zomwe zikutanthauza kupanga insulin yambiri
• Hypogonadotropic hypogonadism - kutanthauza kuchuluka kwa mahomoni ogonana otsika

Kodi ndi mayeso otani omwe amachitidwa kuti aone kuchuluka kwa leptin m'magazi?

Kuchuluka kwa leptin kumatha kuyezedwa ndi kuyeza magazi. Komabe, madokotala nthawi zambiri samayesa kuchuluka kwa leptin kwa aliyense. Amalangiza kuyesa leptin pazochitika zotsatirazi:

• Ngati mwana wanu wamng'ono ali ndi kunenepa kwambiri kwa kalasi III .
• Ngati muli ndi kunenepa kwambiri komanso njala nthawi zonse .

Kodi kuchuluka kwa leptin m'magazi kuyenera kukhala kotani?

Mlingo wa Leptin nthawi zambiri umakhala wosiyana ndi:

• Kwa akazi: 0.5 mpaka 15.2 nanograms pa mililita imodzi (ng/mL)
• Kwa amuna: 0.5 mpaka 12.5 nanograms pa milliliter (ng/mL)

Koma kumbukirani kuti, kuchuluka kwa nthawi yoyezera kumeneku kumatha kusiyana pang'ono pakati pa ma laboratories osiyanasiyana. Chifukwa chake, ndi bwino kuyang'ana kuchuluka kwa nthawi yoyezera pa lipoti lanu. Kapena, ndi bwino kufunsa dokotala wanu za izi.

Kodi ndingawonjezere bwanji kuchuluka kwa leptin m'magazi anga?

Kunena zoona, palibe chomwe tingachite kuti tiwonjezere kuchuluka kwa leptin m'thupi lathu kuti tichepetse njala ndi chilakolako cha chakudya. Chifukwa, monga tanenera kale, kuchuluka kwa leptin m'thupi lanu kumagwirizana mwachindunji ndi kuchuluka kwa mafuta omwe muli nawo m'thupi lanu.

Kafukufuku wina adapeza kuti anthu omwe samagona mokwanira amakhala ndi hormone ya njala yotchedwa ghrelin yambiri komanso hormone ya leptin yochepa. Choncho, kugona mokwanira komanso kwabwino kungathandize kuwongolera mahomoni anu.

Asayansi akufufuzanso za ubale womwe ulipo pakati pa leptin ndi mtundu wa mafuta otchedwa triglycerides. Kafukufuku wina wasonyeza kuti kuchuluka kwa triglyceride kumakhudza momwe leptin imagwirira ntchito. Koma pali malingaliro osiyanasiyana pankhaniyi. Asayansi ena amaganiza kuti njira yodyera yomwe imachepetsa triglycerides ingathandize kukweza kuchuluka kwa leptin. Koma ena sagwirizana.

Ndi zakudya ziti zomwe zili ndi Leptin yambiri?

Apa ndi pomwe anthu ambiri amalakwitsa. Leptin ndi mahomoni omwe amapangidwa m'thupi lathu, osati michere yomwe tingapeze kuchokera ku chakudya monga vitamini C kapena mapuloteni. Chifukwa chake, palibe chakudya chomwe chili ndi leptin.

Pomaliza, zina mwa zinthu zofunika kwambiri zomwe tiyenera kukumbukira

Leptin ndi chinthu chatsopano chomwe chapezeka, kotero asayansi akuphunzirabe zambiri za iyo, makamaka momwe imakhudzira kunenepa kwambiri ndi kuchepetsa thupi. Monga mukuonera, pamene thupi lanu likutaya mafuta, kuchuluka kwa leptin kumatsika, zomwe zikusonyeza kuti thupi lanu "likusala kudya," zomwe zimapangitsa kuti kuchepetsa thupi kukhale kovuta.

Ngati mukuda nkhawa ndi kulemera kwanu kapena mukufuna malangizo a momwe mungachepetsere thupi lanu bwino, ndi bwino kulankhula ndi dokotala wanu. Muthanso kulankhula ndi katswiri wa matenda a endocrinologist za mapulogalamu ochepetsa thupi.

Kumbukirani, zonsezi ndi zothandiza kuti mukhale ndi thanzi labwino. Ndikofunikira kudziwa bwino thupi lanu.

Leptin , kuwongolera kulemera, mahomoni, njala, kunenepa kwambiri, mafuta, kagayidwe kachakudya