Zonse zomwe mukufuna kudziwa zokhudza mayeso a thyroxine (T4)!

Kodi munamvapo za chithokomiro? Mwina dokotala wanu wakupemphani kuti muyesedwe ndi T4. Ndiye kodi T4 iyi ndi chiyani? N’chifukwa chiyani mayesowa amachitidwa? Mwina muli ndi mafunso ngati awa. Lero, tikambirana za mayeso a T4 awa m’njira yosavuta yomwe mungamvetse.

Kodi mayeso a T4 (thyroxine) ndi chiyani?

Mwachidule, mayeso a T4 (thyroxine) ndi mayeso ofunikira a magazi omwe amawunika momwe chithokomiro chanu chikugwira ntchito. Angathandizenso kuzindikira matenda okhudzana ndi chithokomiro.

Tangoganizirani, chithokomiro cha chithokomiro ndi kachithokomiro kakang'ono kooneka ngati gulugufe komwe kali kutsogolo kwa khosi lanu, pamwamba pa khosi lanu. Ndi gawo la dongosolo la endocrine la thupi lathu. Ndi chithokomiro chomwe chimapanga mahomoni a chithokomiro ndikuwatulutsa m'magazi. Kenako mahomoni awa amayenda m'magazi ndikukhudza ziwalo zosiyanasiyana m'thupi lathu.

Thyroxine, yomwe imadziwikanso kuti T4 , ndi mahomoni ambiri omwe amatulutsidwa ndi chithokomiro chanu. Ngati kuchuluka kwa T4 m'magazi anu kuli kokwera kapena kochepa, kungakhale chizindikiro cha matenda a chithokomiro.

Madokotala amayesa kuchuluka kwa T4 mwa kutenga magazi. Thyroxine (T4) iyi imabwera m'njira ziwiri:

• Bound T4: Izi zimagwirizanitsidwa ndi mapuloteni, kotero sizingalowe mosavuta m'maselo a thupi.
• T4 Yaulere: Iyi ndi T4 "yaulere" yomwe imalowa m'maselo a thupi ndikugwira ntchito yake.

Chifukwa chake, pali mayeso angapo omwe amayesa kuchuluka kwa T4. Kuyesa magazi komwe kumayesa T4 yaulere komanso T4 yomangidwa kumatchedwa mayeso onse a T4 . Mayeso ena amagazi amayesa T4 yaulere yokha. Ndipotu, madokotala nthawi zambiri amagwiritsa ntchito mayeso aulere a T4 kuti aone momwe chithokomiro chikugwira ntchito chifukwa ndi olondola kwambiri kuposa mayeso onse a T4.

Dokotala wanu mwina adzachitanso mayeso a TSH (Chithokomiro Cholimbikitsa Hormone) pamodzi ndi mayeso anu a T4. TSH ndi mahomoni opangidwa ndi pituitary gland yanu. TSH iyi imalimbikitsa chithokomiro chanu kuti chipange mahomoni a T4 ndi T3 (triiodothyronine) .

Ndipotu, njira yabwino kwambiri yowunikira momwe chithokomiro chimagwira ntchito ndi kuyesa kwa TSH. Ngati chiphatikizidwa ndi kuyesa kwa TSH, mayeso a T4 angapereke chithunzi cholondola cha momwe chithokomiro chimagwira ntchito. Sizingakhale zofunikira kuyeza milingo ya T4 m'matenda onse a chithokomiro.

Pali mayina ena angapo a mayeso a T4:

• Thyroxine yaulere
• Kuchuluka konse kwa T4
• Chophimba cha Thyroxine
• Kuchuluka kwa T4 kwaulere
• Chizindikiro chaulere cha T4 (FTI)

Kodi thyroxine (T4) ndi chiyani ndipo imagwira ntchito bwanji?

Thyroxine (T4), yomwe imadziwikanso kuti tetraiodothyronine , ndiye mahomoni akuluakulu omwe amatulutsidwa m'magazi ndi chithokomiro chanu. Chithokomiro chimatulutsanso mahomoni ochepa otchedwa triiodothyronine (T3) . Chifukwa T4 ndi T3 zimagwira ntchito limodzi, zonsezi zimatchedwa "mahomoni a chithokomiro."

Tsopano, onani, mahomoni ndi mankhwala omwe amayang'anira zochitika zosiyanasiyana m'matupi athu. Amanyamula mauthenga kudzera m'magazi kupita ku ziwalo zathu, minofu, ndi minofu ina. Zizindikirozi zimauza matupi athu zomwe tiyenera kuchita komanso nthawi yoti tichite.

T4 yomwe imatulutsidwa ndi chithokomiro chanu sigwira ntchito , zomwe zikutanthauza kuti sikhudza mwachindunji maselo a thupi lanu. Komabe, chiwindi chanu ndi impso zanu zimasintha thyroxine yambiri iyi kukhala triiodothyronine (T3) , mahomoni ogwira ntchito omwe amakhudza maselo a thupi lanu.

Pamodzi, T4 ndi T3 zimayang'anira ntchito zingapo zofunika kwambiri m'thupi lathu. Nazi zitsanzo zingapo:

• Kuchuluka kwa kagayidwe kachakudya m'thupi: Ichi ndi kuchuluka kwa chakudya chomwe mumadya chomwe chimasanduka mphamvu.
• Ntchito ya mtima ndi dongosolo logaya chakudya.
• Kulamulira minofu.
• Kukula kwa ubongo.
• Kusamalira mafupa.

Thyroxine yopangidwa

Madokotala amapereka mtundu wa thyroxine wopangidwa wotchedwa levothyroxine pochiza hypothyroidism , vuto lomwe chithokomiro sichigwira ntchito mokwanira. Ikhozanso kuperekedwa pamodzi ndi opaleshoni ndi mankhwala ena a mitundu ina ya khansa ya chithokomiro.

N’chifukwa chiyani ndikufunika mayeso a T4 (thyroxine)?

Madokotala amagwiritsa ntchito mayeso a T4 kuti awone momwe chithokomiro chanu chikugwira ntchito. Nazi zifukwa zina zomwe dokotala wanu angalangize mayeso a T4 (kuwonjezera pa mayeso a TSH):

• Ngati muli ndi zotsatira zosazolowereka za mayeso a thyroid-stimulating hormone (TSH) , fufuzani zambiri.
• Dziwani hyperthyroidism ( chithokomiro chogwira ntchito mopitirira muyeso) kapena hypothyroidism (chithokomiro chogwira ntchito mopitirira muyeso).
• Ngati mukumwa mankhwala obwezeretsa mahomoni a chithokomiro (mankhwala), yang'anirani kuchuluka kwa T4 yanu.
• Yesani makanda obadwa kumene kuti muwone ngati ali ndi hypothyroidism.
• Yesani matenda ena monga goiter ( chotupa cha pakhosi), timibulu ta chithokomiro ( zotupa mu chithokomiro), ndi mavuto a pituitary gland yanu kapena hypothalamus .
• Yang'anani ngati mahomoni a chithokomiro ali otsika chifukwa cha vuto la pituitary (hypothyroidism).

Apanso, madokotala amalamula mayeso aulere a T4 pafupipafupi kuposa mayeso onse a T4 . Muzochitika zina zapadera, monga panthawi ya mimba, mayeso onse a T4 angafunike m'malo mwa mayeso aulere a T4.

Ndani amachita mayeso a magazi a T4 (thyroxine)?

Kawirikawiri, katswiri wa matenda a phlebotomist ndiye amakoka magazi, omwe ndi omwe amakokanso magazi a T4. Komabe, wogwira ntchito zachipatala aliyense wophunzitsidwa kukoka magazi akhoza kuchita izi. Kenako amatumiza chitsanzo cha magazi ku labu. Kumeneko, wasayansi wa labotale yachipatala amakonza chitsanzocho ndikuchiyesa pogwiritsa ntchito makina otchedwa analyzers .

Kodi ndingakonzekere bwanji mayeso a T4 (thyroxine)?

Nthawi zambiri simuyenera kuchita chilichonse chapadera poyesa T4. Komabe, kutengera chifukwa choyesera, mungafunike kusiya kumwa mankhwala ena kapena zowonjezera. Komabe, dokotala wanu adzakupatsani malangizo enieni okhudza izi.

Chofunika: Biotin ndi mankhwala owonjezera omwe amaperekedwa kwa dokotala omwe angayambitse kuti mayeso ena a chithokomiro awoneke ngati osazolowereka, ngakhale atakhala abwinobwino. Chifukwa chake, tikukulimbikitsani kuti musiye kumwa mankhwala owonjezera a biotin masiku atatu mpaka asanu musanayesedwe magazi okhudzana ndi chithokomiro .

Kodi mungayembekezere chiyani mukayezetsa magazi a T4 (thyroxine)?

Mukayezetsa magazi kapena kutengedwa magazi anu, mutha kuyembekezera zinthu monga:

• Mudzakhala pampando. Kenako dokotala wa matenda a phlebotomist adzayang'ana manja anu ndikusankha mtsempha wosavuta kuupeza. Nthawi zambiri izi zimakhala mkati mwa mkono wanu, kumbuyo kwa chigongono chanu.
• Mtsempha ukapezeka, malowo amayeretsedwa ndi kutsukidwa ndi mankhwala ophera tizilombo.
• Kenako singano yaying'ono imalowetsedwa mumtsempha wanu ndipo magazi amatengedwa. Mungamve kuyabwa pang'ono panthawiyi.
• Singano ikalowetsedwa, magazi ochepa amasonkhanitsidwa mu chubu choyesera.
• Magazi akatengedwa, singano imachotsedwa ndipo chidutswa cha thonje kapena gauze chimayikidwa pamalopo kuti magazi asiye kutuluka.
• Kenako bandeji imayikidwa pamalopo. Kenako ntchito yanu yatha.

Njira yonseyi nthawi zambiri imatenga mphindi zosakwana zisanu .

Kodi mungayembekezere chiyani mutalandira mayeso a T4 (thyroxine)?

Dokotala wa matenda a phlebotomist akatenga magazi anu, amatumizidwa ku labotale kuti akayesedwe. Zotsatira za mayeso zikapezeka, dokotala wanu adzakuuzani zotsatira zake.

Kodi zoopsa za kuyezetsa magazi a T4 (thyroxine) ndi ziti?

Kuyezetsa magazi ndi gawo lofala kwambiri komanso lofunikira pakuyezetsa magazi ndi kuyezetsa magazi. Zoopsa za kuyezetsa magazi a T4 ndizochepa kwambiri . Mutha kumva mabala kapena kupweteka pamene magazi akutengedwa, koma izi zidzatha msanga.

Kodi ndidzadziwa liti zotsatira za mayeso anga a T4 (thyroxine)?

Nthawi zambiri, muyenera kulandira zotsatira za mayeso anu a T4 mkati mwa masiku awiri ogwira ntchito . Komabe, zingatenge nthawi yayitali.

Kodi zotsatira za mayeso a T4 (thyroxine) ndi ziti?

Malipoti oyezetsa magazi, kuphatikizapo malipoti oyezetsa T4, nthawi zambiri amakhala ndi izi:

• Dzina la mayeso a magazi kapena zomwe zinayesedwa m'magazi anu.
• Chiwerengero kapena muyeso wa zotsatira za mayeso anu a magazi.
• Umenewo ndiye muyeso wabwinobwino wa mayeso.
• Chidziwitso chomwe chimasonyeza ngati zotsatira zanu ndi zabwinobwino kapena zoyipa, kapena zapamwamba kapena zochepa.

Kodi kuchuluka kwa T4 kwaulere ndi kotani?

Mlingo wabwinobwino wa T4 yaulere umasiyana malinga ndi zaka zanu . Kawirikawiri, kuchuluka kwa T4 yaulere mwa anthu athanzi ndi motere:

• Ana osapitirira zaka 5: 0.8 - 2.8 nanograms pa deciliter (ng/dL)
• Ana azaka zapakati pa 6 ndi 15: 0.8 - 2.1 ng/dL
• Achinyamata aamuna azaka zapakati pa 16 ndi 17: 0.8 - 2.8 ng/dL
• Atsikana azaka zapakati pa 16 ndi 17: 0.8 - 1.5 ng/dL
• Akuluakulu azaka zopitilira 18: 0.9 - 1.7 ng/dL

Dziwani: Kuchuluka kwa T4 kwachibadwa kumatha kusiyana pang'ono pakati pa ma laboratories. Onetsetsani kuti mwayang'ana kuchuluka kwa zotsatira zanu, monga momwe zalembedwera pa lipoti lanu la labu. Ngati muli ndi mafunso okhudza zotsatira zanu, funsani dokotala wanu.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa T4 (thyroxine) kwakwera kwambiri?

Ngati kuchuluka kwa T4 kapena T4 yanu yaulere kuli kokwera kuposa masiku onse, kungakhale chizindikiro cha matenda otchedwa thyrotoxicosis . Izi zitha kuchitika chifukwa cha zinthu zingapo, kuphatikizapo hyperthyroidism ( chithokomiro chogwira ntchito mopitirira muyeso), kutupa kwa chithokomiro (thyroiditis) , komanso kumwa mankhwala ambiri a chithokomiro.

Matenda a thyrotoxicosis amachititsa kuti kagayidwe kachakudya kachepe msanga. Izi zitha kukhala zoopsa pa thanzi lanu. Zizindikiro zina za thyrotoxicosis ndi izi:

• Kuchepetsa thupi popanda chifukwa.
• Kuchuluka kwa maulendo opita kuchimbudzi.
• Kugunda kwa mtima mofulumira kapena kosasinthasintha (arrhythmia) .

Ngati muli ndi zizindikiro za thyrotoxicosis, ndikofunikira kwambiri kukaonana ndi dokotala wanu.

Ngakhale kuti kuchuluka kwa T4 kwaulere ndi kwabwinobwino, matenda ena omwe angayambitse kuchuluka kwa T4 ndi monga mimba ndiKumwa mapiritsi oletsa kubereka omwe ali ndi estrogen . M'zochitika zonsezi, izi zili choncho chifukwa kuchuluka kwa estrogen kumakhala kwakukulu. Estrogen imawonjezera kuchuluka kwa mapuloteni omwe amalumikizana ndi T4, zomwe zimawonjezera T4 yonse (monga, T4 yaulere + yolumikizana ndi mapuloteni).

Kodi chimachitika ndi chiyani ngati kuchuluka kwa T4 (thyroxine) kutsika kwambiri?

Ngati kuchuluka kwa T4 m'magazi anu kuli kotsika kuposa masiku onse, nthawi zambiri kumasonyeza hypothyroidism (chithokomiro chosagwira ntchito bwino). Hypothyroidism ingakhale ndi zifukwa zingapo. Zitsanzo zikuphatikizapo matenda ena odziteteza ku matenda a autoimmune , kusalandira ayodini wokwanira muzakudya zanu, komanso kugwiritsa ntchito mankhwala ena.

Hypothyroidism imachepetsa kagayidwe kachakudya m'thupi. Zizindikiro zina ndi izi:

• Kutopa.
• Kulephera kupirira chimfine.
• Kugunda kwa mtima kochepa.
• Kulemera.

Ngati muli ndi zizindikiro za hypothyroidism, ndikofunikira kwambiri kulankhula ndi dokotala wanu.

Kodi ndiyenera kuda nkhawa ngati zotsatira zanga za mayeso a T4 (thyroxine) zili zochepa kapena zapamwamba?

Zotsatira za mayeso aulere a T4 nthawi zambiri zimakhala zolondola. Komabe, zinthu zina zingakhudze zotsatira zake. Mwachitsanzo:

• Mankhwala ena kapena zowonjezera.
• Mimba.
• Matenda aakulu kapena kusowa zakudya m'thupi.

Dokotala wanu adzaganizira izi potanthauzira zotsatira zanu.

Ngati zotsatira za mayeso anu a T4 sizili bwino, dokotala wanu angafune kuti muyesedwenso mayeso ena a chithokomiro kuti akuthandizeni kupeza matenda. Mayesowa angaphatikizepo:

• Kuyesa kwa T3 (Triiodothyronine) (hormone ina ya chithokomiro).
• Mayeso a TSH (Chithokomiro Cholimbikitsa Hormone).
• Mayeso ozindikira matenda a Graves (matenda odziteteza okha omwe amayambitsa hyperthyroidism).
• Mayeso oti adziwe matenda a Hashimoto (matenda odziteteza okha omwe amayambitsa hypothyroidism).

Kodi kuchuluka kwa TSH (hormone yolimbikitsa chithokomiro) ndi T4 (thyroxine) kumagwirizana bwanji?

Ma TSH ndi T4 zimakhudzana mwachindunji, chifukwa mahomoni olimbikitsa chithokomiro (TSH) amayambitsa kupanga thyroxine (T4), ndipo kuchuluka kwa T4 kwakanthawi kumaletsa kutulutsidwa kwa TSH.

Mukayesedwa magazi kuti muwone momwe chithokomiro chanu chimagwirira ntchito komanso kuchuluka kwa TSH, kuchuluka kwa mahomoni osiyanasiyana kumatha kusonyeza matenda osiyanasiyana. Tiyeni tiwone momwe zimagwirira ntchito.

TSH yotsika komanso T4 yachibadwa

Ma TSH otsika ndi T4 yabwinobwino nthawi zambiri amaonedwa ngati subclinical hyperthyroidism."Subclinical" amatanthauza kuti vutoli silimayambitsa zizindikiro zilizonse, kapena zizindikiro sizinayambebe. Kafukufuku wasonyeza kuti pafupifupi 16% ya anthu onse ali ndi vutoli la subclinical hyperthyroidism.

Ngati zotsatira za mayeso anu a magazi zikusonyeza zotsatirazi, dokotala wanu mwina adzapitiriza kuyang'anira kuchuluka kwa magazi anu kuti awone ngati asintha ndikupangitsa kuti chithokomiro chanu chizigwira ntchito mopitirira muyeso.

TSH yotsika komanso T4 yokwera

Kuchepa kwa TSH ndi kuchuluka kwa T4 nthawi zambiri kumasonyeza hyperthyroidism . Izi zili choncho chifukwa chakuti chithokomiro chanu chimapanga T4 yochuluka chifukwa cha vuto. Kuchuluka kwa T4 kumeneku kumalepheretsa hypothalamus yanu kutulutsa TSH.

TSH yotsika komanso T4 yotsika

Ngati milingo yonse ya TSH ndi T4 ili yotsika, zimasonyeza kuti pali vuto ndi pituitary gland yanu. Mwachitsanzo, chinthu chonga pituitary adenoma yayikulu sichingatulutse TSH yokwanira kuti ilimbikitse kupanga T4. Izi ndi zotsatira zosazolowereka.

TSH yapamwamba ndi T4 yachibadwa

Ngati TSH yakwera ndipo T4 yakhala yabwinobwino, nthawi zambiri imaonedwa ngati subclinical hypothyroidism (yomwe imatchedwanso mild thyroid failure). Matendawa amakhudza pakati pa 3% ndi 8% ya anthu.

Ngati zotsatira za mayeso anu a magazi zikuwonetsa zotsatirazi, dokotala wanu mwina adzapitiriza kuyang'anira kuchuluka kwa magazi anu kuti awone ngati asintha ndikupangitsa kuti mukhale ndi hypothyroidism.

TSH yapamwamba ndi T4 yotsika

Ngati TSH ili pamwamba ndipo T4 ili pansi, nthawi zambiri zimasonyeza hypothyroidism ( chithokomiro chosagwira ntchito bwino chifukwa cha vuto lalikulu la chithokomiro). Izi zili choncho chifukwa pali vuto ndi chithokomiro chanu chomwe chimapangitsa kuti kupanga T4 kuchepe, ndipo chithokomiro chanu cha pituitary chikuyankha potulutsa TSH yochuluka kuti chilimbikitse chithokomiro kupanga T4 yambiri.

TSH yapamwamba ndi T4 yapamwamba

Ngati milingo yonse ya TSH ndi T4 ili yokwera, zimasonyeza kuti pali vuto ndi pituitary gland yanu. Izi zikutanthauza kuti pituitary gland imatulutsa TSH yochuluka, zomwe zimapangitsa kuti chithokomiro chanu chipange T4 yochuluka. Izi ndi zotsatira zosazolowereka kwambiri .

Zinthu zomwe muyenera kukumbukira kuchokera pa zonsezi (Uthenga Wopita Nawo Kunyumba)

Ndi zachilendo kuchita mantha mukaona zotsatira zosazolowereka. Koma musachite mantha . Matenda a chithokomiro, makamaka hypothyroidism, ndi ofala kwambiri ndipo amatha kuchiritsidwa.Dokotala wanu adzakuuzani ngati pakufunika mayeso ena kuti mupeze chomwe chikuyambitsa kuchuluka kwa T4 kosazolowereka. Musazengereze kufunsa mafunso kapena kupanga nthawi yokumana ndi dokotala wanu kuti mukambirane zambiri za zotsatira zanu. Ndikofunikira kudziwa zambiri za thanzi lanu.

Thyroxine , mayeso a T4, chithokomiro, mahomoni, TSH, hypothyroidism, hyperthyroidism