Tiyeni tiphunzire za mayeso a ACTH Stimulation Test m'njira yosavuta.

Kodi nthawi zambiri mumamva kutopa, kutopa, kapena kuchepa thupi? Mukapita kwa dokotala, angasankhe kuyesa mahomoni anu. Makamaka, mahomoni a cortisol. Chifukwa chake, mayeso akulu omwe amachitidwa kuti awone ngati kuchuluka kwa cortisol m'magazi anu kuli bwino ndi mayeso a ACTH Stimulation Test. Ngakhale dzinalo lingamveke lovuta pang'ono, kwenikweni ndi losavuta. Tiyeni tikambirane za zonsezi lero.

Mwachidule, kodi mayeso a ACTH Stimulation Test ndi chiyani?

Iyi ndi mayeso azachipatala. Kunena zoona, ikuyang'ana momwe ziwalo zanu ziwiri zotchedwa adrenal glands zimayankhira ku mahomoni otchedwa ACTH (Adrenocorticotropic hormone) omwe amachokera muubongo wathu. Kodi izi zikumveka zosokoneza pang'ono? Chabwino, tiyeni tiganizire motere.

Tangoganizani kuti pituitary gland muubongo mwanu ili ngati manejala wa kampani yayikulu. Tizilombo tating'onoting'ono ta adrenal pamwamba pa impso zanu tili ngati antchito awiri ogwira ntchito mu kampani imeneyo.

Woyang'anira (pituitary gland) akafuna kuchitapo kanthu, amatumiza uthenga wotchedwa 'ACTH' kwa ogwira ntchito (adrenal glands). Uthengawu ukalandiridwa, ogwira ntchito (adrenal glands) amapanga mahomoni otchedwa 'cortisol' ndikutulutsa m'thupi. Cortisol iyi ndi mahomoni ofunikira kwambiri m'thupi lathu. Imathandiza pazinthu zambiri monga kulamulira kupsinjika maganizo, kuwongolera kuchuluka kwa shuga m'magazi, komanso kuwongolera kuthamanga kwa magazi.

Chifukwa chake, chomwe mayeso a ACTH Stimulation Test amachita ndichakuti timalowetsa hormone ya ACTH yopangidwa kunja (yotchedwa cosyntropin) m'thupi lanu ndikuwona ngati ma adrenal glands anu (ogwira ntchito) amayankha ndi kupanga cortisol moyenera.

Kuyesaku kumagwiritsidwa ntchito makamaka pozindikira vuto lotchedwa 'adrenal insufficiency' . Izi zikutanthauza kuti ma adrenal glands sakupanga cortisol yokwanira. Izi zagawidwa m'mitundu itatu.

Kodi dokotala amakuuzani kuti muchite mayeso awa pazochitika ziti?

Pakhoza kukhala zifukwa zingapo zomwe dokotala wanu angakulimbikitseni mayesowa.

• Ngati mayeso am'mbuyomu a magazi adawonetsa kuchuluka kwa cortisol kotsika: Ngati mudayesedwapo magazi pazifukwa zina zomwe zidawonetsa kuchuluka kwa cortisol kotsika, mungapemphedwe kuti muchite mayesowa kuti mutsimikizire.
• Ngati muli ndi zizindikiro za kulephera kwa adrenal: Monga tafotokozera kale, ngati muli ndi zizindikiro monga kutopa kosalekeza, kuchepa thupi, kupweteka m'mimba, nseru, chizungulire, komanso kuthamanga kwa magazi, mayesowa amachitika kuti adziwe ngati vutoli ndi lomwe limayambitsa.
• Ngati mwakhala mukumwa mankhwala a steroids kwa nthawi yayitali: Mukagwiritsa ntchito mankhwala a glucocorticoid monga prednisone kwa nthawi yayitali, ma glands anu a pituitary ndi adrenal amatha kusiya kugwira ntchito kwakanthawi. Chifukwa chake, mukasiya kumwa mankhwalawo, mayesowa amachitidwanso kuti awone ngati ma glands akugwiranso ntchito bwino.

Kodi muyenera kukonzekera bwanji musanayese mayeso?

Izi ndizofunikira kwambiri. Muyenera kutsatira malangizo a dokotala wanu molondola. Nthawi zambiri, mutha kunena zinthu ngati izi.

• Kusala Kudya: Mungapemphedwe kuti musadye kapena kumwa chilichonse kwa maola pafupifupi 6 musanayesedwe. Madzi okha ndi omwe amaloledwa.
• Zoletsa zochita: Mungapemphedwe kupewa zochita monga kuchita masewera olimbitsa thupi kwa maola 12-24 mayeso asanayambe.
• Chakudya: Nthawi zina mungapemphedwe kudya zakudya zomwe zili ndi chakudya chambiri.
• Kusiya mankhwala: Mankhwala ena omwe mumamwa (makamaka ma steroid creams, mapiritsi, kapena inhalers) angakhudze zotsatira za mayeso. Chifukwa chake, dokotala wanu angakupempheni kuti musiye kumwa mankhwalawa kwakanthawi. Musasiye kumwa mankhwala anu musanafunse dokotala wanu kaye.

Chabwino, tsopano tiyeni tiwone zomwe zidzachitike patsiku la mayeso.

Izi sizowopsa monga momwe mungaganizire. Nthawi zambiri zimachitika kuchipatala kapena ku chipatala cha endocrinologist. Izi ndi zomwe zimachitika pang'onopang'ono.

1. Kutenga magazi oyamba: Choyamba, namwino adzatenga magazi kuchokera m'mitsempha yomwe ili m'dzanja lanu. Izi zidzayang'ana kuchuluka kwa cortisol m'magazi anu musanayambe kuyeza.

2. Kupereka jakisoni: Kenako, namwino adzakupatsani jakisoni wokhala ndi ACTH yopangidwa (cosyntropin). Nthawi zambiri imaperekedwa mu minofu ya mkono wanu. Zidzamveka ngati nyerere yaying'ono ikukulumani, koma idzatha pakapita masekondi angapo.

3. Zitsanzo za magazi zachiwiri ndi zachitatu: Mudzatengedwanso magazi ena mphindi 30 mutalandira jakisoni. Kenako mudzatengedwanso magazi ena patatha mphindi 60. Izi zidzayesa kuchuluka kwa cortisol yomwe adrenal glands yanu yapanga kuyambira mujakisoni.

4. Kutumiza ku labotale: Zitsanzo za magazi zomwe zatengedwa zimatumizidwa ku labotale.

Mukakoka magazi anu, mumangomva kubaya pang'ono. Zimenezo zimatha pakapita kanthawi. Mungamve kachilonda kakang'ono komwe magaziwo anakokedwa, zomwe sizachilendo.

Kodi zotsatira zake zidzapezeka liti ndipo zidzati chiyani?

Zingatenge pafupifupi sabata imodzi kuti zotsatira za mayesowa zibwererenso. Izi zili choncho chifukwa chakuti zotsatira zake zikalandiridwa, dokotala wanu adzazifufuza mosamala ndikuziyerekeza ndi zizindikiro zanu kuti apeze yankho.

Kodi zotsatira zabwinobwino ndi ziti?

Mu munthu wathanzi, pambuyo pa jakisoni wa ACTH, ma adrenal glands ayenera kukonzedwa bwino ndipo kuchuluka kwa cortisol m'magazi kuyenera kukwera kwambiri. Dokotala wanu adzakufotokozerani zomwe zili mu lipoti lanu la labu komanso kuchuluka kwa zomwe zili bwino.

Kodi Zotsatira Zachilendo ndi Chiyani?

• Kulephera Kwambiri kwa Adrenal (ngati pali vuto ndi ma adrenal glands): Kwa munthu amene ali ndi vutoli, ngakhale atapatsidwa jakisoni wa ACTH, kuchuluka kwa cortisol sikukwera konse kapena kumawonjezeka pang'ono kwambiri. Izi zili choncho chifukwa vutoli lili m'ma adrenal glands, ndipo ngakhale atapatsidwa mphamvu yotani kuchokera kunja, sangathe kupanga cortisol.
• Kulephera kwa Adrenal kwachiwiri (ngati pali vuto ndi pituitary gland): Pamene pituitary gland siitulutsa ACTH kwa nthawi yayitali, adrenal glands imachepa pang'onopang'ono ndikuyamba kusagwira ntchito (atrophy). Munthu wotere akapatsidwa jakisoni wa ACTH, adrenal glands yosagwira ntchito sangayankhe nthawi yomweyo. Chifukwa chake, kuchuluka kwa cortisol m'magazi awo kumawonjezeka pang'ono kapena sikuwonjezeka konse.

Nthawi zina, ngati vuto la pituitary gland langoyamba kumene kapena langokhudzidwa pang'ono, kuchuluka kwa cortisol kumatha kukwera pang'ono. Dokotala wanu ndiye munthu woyenera kupanga chisankho pa zonsezi.