Matenda a Addison | Tiyeni tiphunzire za zomwe zimayambitsa, zizindikiro ndi chithandizo m'mawu osavuta

Kodi mumamva kutopa kwambiri komanso kutopa tsiku ndi tsiku? Kuphatikiza pa kupweteka m'mimba ndi nseru, kodi nthawi zina mumakhala ndi chilakolako chachilendo cha zakudya zamchere? Ngakhale izi zingawoneke ngati zinthu wamba, mwina kumbuyo kwa izi pali vuto lomwe sitinamvepo zambiri, koma lomwe liyenera kuthandizidwa bwino. Lero tikulankhula za vuto limodzi lotere, matenda a Addison.

Kodi matenda a Addison ndi chiyani kwenikweni?

Mwachidule, matenda a Addison ndi matenda osatha omwe amapezeka pamene ma adrenal glands m'thupi lathu sapanga mahomoni awiri ofunikira okwanira, cortisol ndi aldosterone .

Tsopano mwina mukudabwa kuti ma adrenal glands ndi chiyani. Awa ndi ma glands awiri ang'onoang'ono, amakona atatu omwe amakhala ngati chivundikiro pamwamba pa impso zathu. Ndi gawo lofunika kwambiri la dongosolo la endocrine la thupi lathu.

• Cortisol: Homoni iyi ndi yofunika kwambiri pa miyoyo yathu. Tangoganizirani mukadwala, mukachita ngozi, kapena mukuchitidwa opaleshoni, thupi lanu limamva kupsinjika kwambiri. Nthawi ngati zimenezi, homoni ya cortisol imathandiza thupi kuthana ndi kupsinjika kumeneko. Sikuti kokha, komanso imathandiza kuwongolera kuthamanga kwa magazi, kugwira ntchito kwa mtima, chitetezo cha mthupi, komanso kuchuluka kwa shuga m'magazi.

• Aldosterone: Homoni iyi imayang'anira kuchuluka kwa sodium (mchere) ndi potaziyamu m'magazi mwathu. Imawongoleranso kuchuluka kwa madzi omwe impso zathu zimatuluka ngati mkodzo. Izi zimakhudza mwachindunji kuchuluka kwa magazi athu ndi kuthamanga kwa magazi.

Matenda a Addison amadziwikanso kuti primary adrenal insufficiency . Palinso vuto lina lofanana nalo lotchedwa secondary adrenal insufficiency . Mu vutoli, pituitary gland muubongo sipanga mahomoni okwanira otchedwa ACTH . Homoni iyi, ACTH, imalimbikitsa ma adrenal glands kuti apange cortisol.

Kodi pali kusiyana kotani pakati pa matenda a Addison ndi matenda a Cushing?

Musasokoneze awiriwa. N'zosavuta kwambiri.

• Matenda a Addison: Kusakwanira kwa cortisol (ndi aldosterone) m'thupi.
• Matenda a Cushing: Kuwonjezeka kwa cortisol m'thupi.

Ndani amene ali ndi mwayi waukulu wopeza vutoli?

Ngakhale matenda a Addison amatha kuchitika pa msinkhu uliwonse, amapezeka kwambiri pakati pa zaka 30 ndi 50.Pakati pa anthu. Ili ndi vuto losowa kwambiri.

Komanso, anthu omwe ali ndi matenda enaake a chitetezo chamthupi amakhala pachiwopsezo chachikulu chotenga matendawa. Matenda a chitetezo chamthupi ndi pamene chitetezo chamthupi chathu chimaukira maselo athu athanzi molakwika. Anthu omwe ali ndi matenda otsatirawa ali pachiwopsezo chachikulu chotenga matenda a Addison:

• Matenda a shuga amtundu woyamba
• Kuchepa kwa magazi m'thupi koopsa
• Matenda a Manda
• Matenda a chithokomiro chosatha
• Dermatitis herpetiformis
• Vitiligo
• Myasthenia gravis

Kodi zizindikiro za matenda a Addison ndi ziti?

Mu matendawa, kuwonongeka kwa adrenal glands nthawi zambiri kumachitika pang'onopang'ono, pakapita nthawi. Chifukwa chake, zizindikiro zimawonekera pang'onopang'ono. Zizindikirozi zimatha kusiyana malinga ndi munthu.

Ngati akazi ali ndi matendawa, amathanso kukhala ndi zizindikiro monga kusayenda bwino kwa msambo, kutayika tsitsi m'thupi, komanso kuchepa kwa chilakolako chogonana.

Zadzidzidzi: Kodi vuto la Addisonian ndi chiyani?

Nthawi zina, makamaka panthawi ya nkhawa yaikulu m'thupi (monga matenda aakulu, ngozi), zizindikiro zimatha kukulirakulira mwadzidzidzi n'kukhala zoopsa kwa moyo. Izi zimatchedwa Addisonian crisis , kapena acute adrenal failure .

Ngati inu kapena munthu amene mumamudziwa ali ndi zizindikiro zotsatirazi, pitani naye ku Dipatimenti Yothandiza Pangozi (ETU) yapafupi nthawi yomweyo.

Kodi n’chiyani chimayambitsa matenda a Addison?

Chifukwa chachikulu cha matenda a Addison ndi chitetezo chamthupi chomwe chimabwera chifukwa cha chitetezo chamthupi . Mwachidule, chitetezo chamthupi lathu (chitetezo chamthupi) chimaukira minofu yathu yathanzi molakwika. Mu matendawa, chitetezo chamthupi chimaukira mbali yakunja ya adrenal glands (adrenal cortex). Apa ndi pomwe cortisol ndi aldosterone zimapangidwa. Zizindikiro nthawi zambiri sizimawonekera mpaka pafupifupi 90% ya kuwonongeka kumeneku kwachitika. Izi zitha kutenga miyezi, kapena zaka. Ichi ndiye chifukwa cha 75% ya odwala a Addison.

Kale, chifuwa chachikulu chinali chifukwa chachikulu cha izi, ndipo chidakali chifukwa chachikulu m'maiko osatukuka.

Pali zifukwa zina zachilendo:

• Matenda monga HIV/AIDS ndi matenda a bowa.
• Kufalikira kwa maselo a khansa kuchokera kwina kupita ku adrenal glands.
• Kutuluka magazi m'zidutswa za adrenal (kutuluka magazi m'thupi).
• Kuchotsa adrenal glands ndi opaleshoni.
• Matenda monga amyloidosis.

Kodi dokotala amazindikira bwanji matendawa?

Popeza zizindikiro zimawonekera pang'onopang'ono ndipo zimakhala zofala ku matenda ena ambiri, zingakhale zovuta kuzindikira matendawa molondola.

Kawirikawiri, dokotala amakayikira ngati mayeso a magazi akuwonetsa kuti muli sodium yochepa kapena potaziyamu yambiri m'magazi. Mawanga akuda pakhungu ndi chizindikiro china chachikulu chomwe chimapangitsa munthu kukayikira izi.

Ngati dokotala wanu akukayikira matenda a Addison kutengera zizindikiro zanu, adzayitanitsa mayeso ena angapo kuti atsimikizire matendawa.

• Mayeso a magazi: Izi zimayesa kuchuluka kwa sodium, potaziyamu, cortisol, ndi mahomoni a ACTH m'magazi anu.
• Kuyesa kwa ACTH: Izi zimaphatikizapo kubaya jekeseni wa ACTH hormone yopangidwa ndikuyang'ana ngati ma adrenal glands anu amatulutsa cortisol poyankha. Kuchepa kwa cortisol kungasonyeze kuti ma ducts sagwira ntchito mokwanira.
• Kuyesa kwa hypoglycemia komwe kumayambitsa insulin: Izi zimayang'ana ngati vuto lanu likugwirizana ndi pituitary gland.
• Kujambula kwa CT: Izi zitha kuwona ngati adrenal glands yawonongeka kapena ngati pali matenda.

Kodi mankhwala ochizira izi ndi otani?

Matenda a Addison amachiritsidwa posintha mahomoni omwe akusowa m'thupi ndi mankhwala opangidwa.

• Mankhwala otchedwa hydrocortisone amaperekedwa m'malo mwa cortisol.
• Aldosterone imalowetsedwa m'malo ndi mankhwala otchedwa fludrocortisone .

Mlingo wa mankhwalawa umasiyana malinga ndi munthu. Komanso, dokotala wanu angawonjezere mlingo wa mankhwalawa kuti apewe vuto la Addisonian ngati mukukumana ndi nkhawa, monga matenda, ngozi, kapena opaleshoni.

Ngati muli ndi matenda a Addison, kodi mumadzisamalira bwanji?

Ngati muli ndi matendawa, ndikofunikira kwambiri kudzisamalira.

• Nthawi zonse valani chiphaso cha ID kapena chibangili cha chenjezo cha zachipatala kuti akatswiri azachipatala adziwe za matenda anu pakagwa mwadzidzidzi.
• Lankhulani ndi dokotala wanu za zomwe mungachite mukadwala kapena mukuvutika maganizo kwambiri, chifukwa mlingo wa mankhwala anu ungafunike kusinthidwa nthawi ngati izi.
• Pakachitika ngoziFunsani dokotala wanu za kukhala ndi jakisoni wa cortisol pafupi ndi kuphunzitsa wachibale wanu momwe angakupatseni.

Kodi muyenera kupita kwa dokotala nthawi yanji?

Ngati muli ndi matenda a Addison, muyenera kuonana ndi dokotala wanu (nthawi zambiri katswiri wa endocrinologist) nthawi zonse kuti muwonetsetse kuti mlingo wa mankhwala anu ndi woyenera kwa inu.

Ngati mukukumana ndi vuto lalikulu la kupsinjika maganizo, monga ngozi, matenda, kapena imfa ya wokondedwa wanu, imbani dokotala wanu chifukwa mungafunike kusintha mlingo wa mankhwala anu.

Kudziwa kuti muli ndi matenda osatha kungakhale kovuta m'maganizo. Koma nkhani yabwino ndi yakuti matenda a Addison amatha kuthandizidwa bwino ndi mankhwala. Mukapita kwa dokotala nthawi zonse, kumwa mankhwala oyenera, komanso kudzisamalira, mutha kukhala ndi moyo wathanzi komanso wabwinobwino.