Tiyeni tiphunzire za mankhwala a Alpelisib (Vijoice)? (PIK3CA-related overgrowth spectrum - PROS)

Inu, kapena mwana wanu, mwina munauzidwa ndi dokotala wanu kuti muyambe kumwa mankhwala otchedwa Alpelisib (dzina la mtundu: Vijoice). Mukamva dzina la mankhwala apadera otere, ndi zachilendo kuti mafunso ambiri abwere m'maganizo mwanu, monga "Kodi izi zimagwira ntchito bwanji?", "Ndiyenera kumwa bwanji?", "Kodi njira zodzitetezera ndi ziti?" Choncho musachite mantha. Lero, tikambirana za mankhwala otchedwa Alpelisib momveka bwino komanso mosavuta.

Kodi Alpelisib ndi mankhwala amtundu wanji?

Mwachidule, Alpelisib ndi mankhwala omwe amalamulira kukula kosazolowereka komanso kosalamulirika kwa maselo ena m'thupi. Mankhwalawa amagwiritsidwa ntchito makamaka pochiza vuto lomwe ziwalo zina za thupi (monga mkono, mwendo, kapena minofu ina) zimakula kwambiri chifukwa cha kusintha kwa majini otchedwa PIK3CA . Matendawa timawatcha PIK3CA-related overgrowth spectrum (PROS) . Mankhwalawa amagwira ntchito potseka njira yolumikizirana yomwe imayambitsa kukula kosazolowereka kwa maselo, potero amawongolera matendawa.

Dokotala wanu angakupatseni izi pa matenda ena, choncho ngati muli ndi mafunso, lankhulani ndi dokotala wanu za izi.

Zinthu zomwe muyenera kuuza dokotala wanu musanayambe kumwa mankhwala

Kuti mukhale otetezeka komanso kuti mupindule kwambiri ndi mankhwala, ndikofunikira kuuza dokotala wanu izi musanayambe kumwa Alpelisib.

• Ngati muli ndi matenda a shuga: Tiuzeni ngati muli kale ndi matenda a shuga kapena shuga wambiri m'magazi.
• Matenda a m'mapapo: Ngati muli ndi matenda aliwonse a m'mapapo, monga mphumu kapena chibayo.
• Matenda a ziwengo: Onetsetsani kuti mwauza dokotala wanu ngati muli ndi vuto lililonse la ziwengo ku Alpelisib kapena mankhwala ena aliwonse, chakudya, kapena utoto.
• Mimba: Ngati muli ndi pakati, mukufuna kutenga mimba, kapena mukukayikira ngakhale pang'ono kuti muli ndi pakati.
• Ngati ndinu mayi woyamwitsa: Ngati mukuyamwitsa mwana.

Dokotala akadziwa zinthu zimenezi, zidzakhala zosavuta kuti akonze chithandizo chomwe chingakukomereni.

Kodi ndimagwiritsa ntchito bwanji mankhwalawa molondola?

Ndikofunikira kwambiri kutsatira malangizo enieni ogwiritsira ntchito mankhwalawa.

• Imwani mankhwalawo monga momwe dokotala wanenera, nthawi yomweyo tsiku lililonse .
• Musadule kapena kutafuna piritsi ili. Mezani piritsi lonse ndi madzi.
• Ndi bwino kumwa mankhwalawa pamodzi ndi chakudya .
• Pitirizani kumwa mankhwalawo mpaka dokotala wanu atakuuzani kuti musiye. Musasiye mwadzidzidzi, ngakhale mutamva bwino.

Kodi mungachite chiyani ngati piritsi likuvuta kumeza?

Anthu ena, makamaka ana, amavutika kumeza mapiritsi. Ngati zili choncho, nayi momwe mungachitire:

1. Ikani piritsi mu galasi ndi madzi okwana ma ounces 2-4 (pafupifupi 60-120 ml).

2. Pakatha mphindi pafupifupi 5, phwanyani piritsi bwino ndi supuni yoyera ndikusakaniza bwino mpaka litasungunuka m'madzi.

3. Imwani chisakanizochi nthawi yomweyo.

4. Kenako, onjezerani supuni ziwiri kapena zitatu za madzi mu galasi lomwelo, tsukani mankhwala otsala mu galasi, ndipo imwani. Chitani izi mwanjira yoti dontho limodzi la mankhwala lisatayike.

Nanga bwanji ngati nditamwa mankhwala ochulukirapo (overdose)?

Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, musazengereze. Imbani nthawi yomweyo ku National Poisons Information Centre ku Colombo National Hospital . Kapena pitani ku Emergency Treatment Unit (ETU) ya chipatala chapafupi.

Kodi mungachite chiyani ngati mwaphonya mlingo wa mankhwala?

Ngati mwaiwala kumwa mlingo, imwani mwamsanga mukangokumbukira. Komabe, ngati patatha maola osakwana 9 kuti mutenge mlingo wotsatira mukangokumbukira (monga kuchedwa kwa maola opitilira 9), dumphani mlingo womwe mwaphonya. Ingomwani mlingo wotsatira panthawi yomwe mwakonza. Musamwe mlingo umodzi nthawi imodzi kuti mubwezeretse mlingo womwe mwaphonya.

Mankhwala ena omwe angagwirizane ndi mankhwalawa (Kuyanjana kwa Mankhwala)

Mankhwala ena omwe mukumwa angagwirizane ndi Alpelisib ndipo angakhudze mphamvu yake kapena zotsatira zake zoyipa. Chifukwa chake, uzani dokotala wanu ngati mukumwa mankhwala aliwonse otsatirawa kapena zowonjezera zina, mavitamini, kapena mankhwala azitsamba.

• Mankhwala ena omwe amagwiritsidwa ntchito pa khunyu: Mwachitsanzo, `(Carbamazepine)`, `(Phenobarbital)`, `(Phenytoin)`.
• 'Cyclosporine'
• `Eltrombopag`
• `Enzalutamide`
• `Mitotane`
• `Rifampin` (mankhwala a chifuwa chachikulu)
• `St. John's Wort` (mankhwala azitsamba a thanzi la maganizo)
• 'Sulfasalazine'
• `Warfarin` (mankhwala operekedwa kuti aletse magazi kuundana)

Mndandanda uwu sunathe, choncho ndi bwino kuuza dokotala wanu za mankhwala onse omwe mukumwa.

Zinthu zomwe muyenera kusamala nazo kwambiri mukamamwa mankhwala

• Kupimidwa ndi dokotala nthawi zonse: Funsani dokotala wanu nthawi zonse kuti muwone ngati zizindikiro zanu zikuchepa kapena zikuipiraipira. Musalumphe mayeso ofunikira a magazi (magazi).
• Matenda a pakhungu: Anthu ena amatha kukhala ndi matenda a pakhungu ngakhale milungu ingapo atayamba kumwa mankhwalawa.Uzani dokotala wanu nthawi yomweyo ngati mukuyamba kutupa pamodzi ndi zizindikiro monga malungo kapena chimfine. Matendawa amatha kukhala ofiira kapena ofiirira, kenako amatupa ndi kutuluka. Kapena ngati muwona kutupa kofiira pankhope panu, pamilomo, pakhosi, kapena m'khwapa pamodzi ndi kutupa kwa ma lymph nodes, imbani dokotala wanu nthawi yomweyo.
• Kutsegula m'mimba kwambiri komanso kutaya madzi m'thupi: Uzani dokotala wanu ngati muli ndi vuto la kutsegula m'mimba kwambiri, kusanza, kapena thukuta kwambiri . Kutaya madzi ambiri m'thupi lanu (kusowa madzi m'thupi) kungakhale koopsa mukamamwa mankhwalawa.
• Shuga wambiri m'magazi (Hyperglycemia): Mankhwalawa angayambitse shuga wambiri m'magazi. Chiwopsezochi chimakhala chachikulu kwa anthu omwe ali kale ndi matenda a shuga. Uzani dokotala wanu ngati mukumva ludzu kwambiri kuposa nthawi zonse, mukukodza pafupipafupi, mukumva kutopa kwambiri, kapena mukuona zinthu molakwika .
• Pakamwa pouma: Mungakhale ndi pakamwa pouma. Izi zitha kuthetsedwa ndi zinthu monga kutafuna chingamu chopanda shuga ndi kumwa madzi ambiri. Komabe, ngati vutoli likupitirira kapena ndi lalikulu, uzani dokotala wanu.

Zotsatirapo zomwe zingachitike chifukwa cha mankhwala

Kodi mumasunga bwanji mankhwala anu kukhala otetezeka?

• Sungani kutali ndi ana ndi ziweto.
• Sungani pamalo otentha pakati pa madigiri 20 ndi 25 Celsius (68-77 Fahrenheit), omwe ndi kutentha kwabwinobwino kwa chipinda.
• Musagwiritse ntchito mankhwala omwe atha ntchito.
• Mukataya mankhwala osagwiritsidwa ntchito kapena omwe atha ntchito, yang'anani chizindikirocho kuti muwone ngati ali otetezeka kutaya. Ngati mukukayikira, funsani dokotala wanu. Ngati ali otetezeka kutaya, chotsani mapiritsiwo m'botolo ndikusakaniza ndi chinthu monga khofi wogwiritsidwa ntchito, dothi, kapena zinyalala za amphaka, ziyikeni m'thumba kapena chidebe chotsekedwa bwino, ndikuzitaya m'zinyalala.