Kodi njira zanu zotulutsira ndulu zakula? Tiyeni tikambirane za matenda a Caroli!

Kodi nthawi zina mumamva ngati thupi lanu likusintha kukhala lachikasu, kapena mumamva ngati mukumva kupweteka m'mimba mwanu? Anthu ena amatha kumva kutentha thupi ndi kusanza limodzi ndi zizindikiro izi. Chifukwa chimodzi chomwe chingayambitse izi ndi matenda omwe tikambirane lero otchedwa 'Matenda a Caroli.' Tiyeni tiwone chomwe chili, chifukwa chake chimachitika, momwe amapezekera, komanso chithandizo chake.

Mwachidule, kodi matenda a Caroli ndi chiyani?

Tangoganizirani, mkati mwa chiwindi chathu muli machubu ang'onoang'ono otchedwa ndulu . Machubu awa amanyamula madzi am'mimba otchedwa ndulu omwe amapangidwa m'chiwindi kupita kumatumbo ang'onoang'ono. Tsopano, matenda a Caroli awa ndi vuto lomwe machubu a ndulu amakula kuposa masiku onse, ndiko kuti, amatambasuka . Uwu ndi matenda a majini , ndiko kuti, amayamba chifukwa cha kusintha kwa majini athu. Machubu awa akakula motere, ndulu imayamba kusonkhana m'malo moyenda bwino. Izi zikachulukana, miyala ya ndulu imatha kupangika, matenda amatha kuchitika, ndipo nthawi zina ma cysts amatha kupangika.

Mwachidule, ndulu iyenera kuyenda mosavuta popanda kutsekeka. Komabe, pamene ndulu ikukula kwambiri, ndulu imatha kusonkhana mosavuta. Pakapita nthawi, ndulu iyi yosonkhanitsidwa imatha kupanga miyala yaying'ono.

Ngati muli ndi matenda a Caroli, mutha kukhala ndi zizindikiro zambiri za matendawa m'moyo wanu wonse. Zizindikiro nthawi zambiri zimayamba pafupifupi zaka 30 , koma zimatha kuchitika pa msinkhu uliwonse. Mutha kuwona khungu lanu ndi maso anu oyera akusanduka achikasu (zomwe timazitcha kuti jaundice ), ndipo mutha kuyambanso kukhala ndi zizindikiro monga chimfine ndi chimfine nthawi zambiri. Ngakhale kuti vutoli lingakhudze thanzi lanu komanso moyo wanu, pali mankhwala omwe angathandize kuwongolera zizindikiro zanu.

Kodi pali mitundu ina iliyonse ya matenda a Caroli?

Inde, pali mitundu iwiri ikuluikulu ya izi:

• Matenda a Caroli: Mtundu uwu umakhudza njira zotulutsira ndulu zokha. Sizimayambitsa mavuto ena a chiwindi.
• Matenda a Caroli: Uwu ndi mtundu woopsa kwambiri. Pachifukwa ichi, chiwindi chimakhala ndi zipsera, zomwe timazitcha kuti fibrosis .

Kodi matendawa ndi ofala bwanji?

Matenda a Caroli ndi matenda osowa kwambiri . Akuti munthu m'modzi yekha pa anthu miliyoni imodzi ndi amene amadwala matendawa . Choncho si matenda omwe amakhudza anthu ambiri.

Ndiye kodi zizindikiro za matenda a Caroli ndi ziti?

Kawirikawiri, miyala ing'onoing'ono yomwe imapangika mu ducts ya ndulu siimayambitsa zizindikiro zazikulu. Komabe, ngati mwala utseka ducts ya ndulu, ukhoza kutupa. Timatcha izi cholangitis . Apa ndi pamene zizindikiro za matenda a Caroli zimawonekera:

• Ululu kumbali yakumanja ya thupi lanu , nthawi zambiri m'mimba ya pamwamba.
• Kusanza .
• Malungo ndi kuzizira .
• Kuoneka kwachikasu pakhungu ndi maso oyera (jaundice) .
• Kuyabwa .

Kawirikawiri, kuchulukana kwa ndulu kumeneku kungayambitse mtundu wa chotupa cha khansa chotchedwa cholangiocarcinoma m'mitsempha ya ndulu. Ndicho chifukwa chake ndikofunikira kusamala ndi izi.

N’chifukwa chiyani matenda a Caroli amachitika? Kodi zimayambitsa chiyani?

Matenda a Caroli ndi matenda a majini . Izi zikutanthauza kuti amayamba chifukwa cha kusintha kwa majini m'thupi lathu. Nthawi zambiri, amatha kuchitika pang'onopang'ono, zomwe zikutanthauza kuti sapatsiridwa kuchokera ku mibadwomibadwo. Komabe, m'mabanja ena, akuti ndi matenda olamulira autosomal , zomwe zikutanthauza kuti ngati kholo limodzi lili nawo, ana nawonso akhoza kuwatenga.

Matenda a Caroli amayamba chifukwa cha kusintha kwa majini mu jini yotchedwa PKHD1 . Jini iyi imapanga mapuloteni omwe amathandiza kuti ndulu ndi impso zimere panthawi ya umuna, kutanthauza kuti, mwana akamabadwa. Popeza matenda a Caroli ndi matenda a Caroli zimagwirizana, ofufuza amakhulupirira kuti jini ya PKHD1 imagwiranso ntchito mu matenda a Caroli. Komabe, kafukufuku wowonjezereka akufunika kuti adziwe izi.

Kodi madokotala amazindikira bwanji matenda a Caroli?

Mukapita kwa dokotala, choyamba adzakuyesani thupi ndikufunsani za zizindikiro zanu. Kenako, adzayitanitsa mayeso ena a magazi, monga Comprehensive Metabolic Panel (CMP), yomwe imaphatikizapo ma enzymes a chiwindi . Ngati pali kukwera kwa ma enzymes awa, zitha kusonyeza kuti ndulu yatsekedwa.

Kuwonjezera pa kuyezetsa magazi, dokotala wanu mwina angakupatseni mayeso angapo okhudza kujambula zithunzi/radiology , omwe ndi mayeso omwe amayang'ana mkati mwa thupi lanu. Izi zikuphatikizapo:

• Ultrasound ya m'mimba
• Kujambula kwa CT (computed tomography scan)
• Kujambula kwa MRI (magnetic resonance imaging scan)

Kuphatikiza apo, dokotala wanu angakufunseninso kuti muyesedwe ndi ERCP (endoscopic retrograde cholangiopancreatography) . Izi zimaphatikizapo kuyika chubu chaching'ono, chosinthasintha (chotchedwa endoscope ) kudzera pakamwa panu ndikutsika m'mimba mwanu kupita ku ducts za bile. Ndi ERCP iyi, dokotala wanu amatha kuyang'ana ducts za bile ndi chiwindi chanu kuti awone ngati pali zotupa kapena zipsera.

Chinthu china n'chakuti, dokotala wanu angakufunseninso kuti muchite mtundu wapadera wa MRI wotchedwa MRCP (magnetic resonance cholangiopancreatography) . Izi zitha kuyeza kukula kwa ducts za bile. Zingathenso kuyang'ana miyala ya ndulu.

Kodi mankhwala ake ndi otani? Kodi angachiritsidwe?

Kunena zoona, matenda a CaroliPalibe mankhwala pakadali pano. Komabe, pali mankhwala omwe angathandize kuchepetsa zizindikiro ndikupewa mavuto. Izi zidzafuna kuti mugwire ntchito ndi gulu la madokotala omwe ndi akatswiri m'magawo osiyanasiyana. Izi zikuphatikizapo:

• Katswiri wa majini
• Katswiri wa matenda a m'mimba
• Katswiri wa chiwindi/Hepatologist
• Dokotala wa urologist ( monga momwe impso zimakhudzidwiranso)
• Dokotala wodziwa bwino matenda a impso (Nephrologist)
• Katswiri wa radiology ( wa zinthu monga ma scan)
• Dokotala wochita opaleshoni yopatsirana (ngati pakufunika)

Chithandizo cha matenda a Caroli chimadalira komwe kuli m'chiwindi komwe njira yotulutsira ndulu yotambasuka ili.

• Nthawi zina opaleshoni: Ngati ndulu yokulirapo ili kumanzere kapena kumanja kwa chiwindi, dokotala wanu angachotse gawo limenelo la chiwindi mwa opaleshoni. Izi zimatchedwa hemi-hepatectomy . Anthu omwe achotsa gawo la chiwindi mwanjira imeneyi nthawi zambiri sakhala ndi zizindikiro kachiwiri.
• Mankhwala: Komabe, ngati ndulu yotambasuka yafalikira m'chiwindi chonse, dokotala wanu angakupatseni mankhwala opha tizilombo toyambitsa matenda otchedwa cholangitis . Komanso, mankhwala otchedwa ursodeoxycholic acid angathandize pa mavuto ena omwe amabwera chifukwa cha matenda a Caroli.
• Maopaleshoni ena: Nthawi zina, dokotala wanu angakulangizeni kuti mugwiritse ntchito njira yochotsera ndulu m'chiwindi.
• Kuika chiwindi: Pa milandu yoopsa kwambiri, kuyika chiwindi ndi njira yabwino kwambiri yothandizira.

Kodi mungakhale ndi moyo wautali bwanji ndi matenda a Caroli?

Matenda a Caroli okha sakulongosola mwachindunji nthawi yomwe munthu ali ndi moyo. Nthawi yomwe munthu amayembekezera kukhala ndi moyo imakhudzidwa ndi mavuto omwe angayambitse. Izi ndi izi:

• Cholangitis: Cholangitis yoopsa iyi, yomwe ingayambitsidwe ndi miyala ya ndulu m'mitsempha ya ndulu, imafuna chithandizo chadzidzidzi ndipo imatha kupha mkati mwa maola kapena masiku.
• Khansa ya m'mapapo a ndulu (cholangiocarcinoma): Khansa iyi imatha kuyamba chifukwa cha kutupa kwa nthawi yayitali komanso kutsekeka kwa m'mapapo a ndulu. Kuzindikira msanga ndi chithandizo ndikofunikira kuti zinthu ziyende bwino.
• Kulephera kwa chiwindi:Ngati kutupa kwa ndulu kukupitirira, pamapeto pake kungayambitse matenda aakulu monga kulephera kwa chiwindi.

Chofunika kwambiri ndi kusamalira matenda a cholangitis. Ngati matenda a cholangitis athandizidwa bwino ndipo dokotala amawayang'anira nthawi zonse, anthu omwe ali ndi matenda a Caroli akhoza kukhala ndi moyo wabwino.

Kodi pali njira yopewera matenda a Caroli awa?

Matenda a Caroli ndi matenda obadwa nawo m'majini , kotero sangapewedwe chifukwa ndi chinthu chomwe chimabwera ndi majini athu.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati mukupeza zizindikiro za matenda a Caroli - monga kupweteka m'mimba mwanu, kusanza, kutentha thupi, ndi chikasu - muyenera kuwonana ndi dokotala. Musazengereze.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala?

Ndi bwino kufunsa mafunso awa mukapita kwa dokotala:

• Kodi ndili ndi matenda a Caroli kapena matenda a Caroli?
• Kodi vuto langa ndi lalikulu bwanji kutengera zotsatira za ma scan anga?
• Kodi njira yabwino kwambiri yothandizira ndi iti?
• Kodi pali mankhwala aliwonse omwe angathandize kuchepetsa zizindikiro zanga kapena kupewa mavuto?
• Kodi ndingathe kuchitidwa opaleshoni? Ngati ndi choncho, ndi opaleshoni yamtundu wanji yomwe ndiyenera kuchita?
• Kodi zoopsa ndi ubwino wa opaleshoni ndi ziti?
• Kodi zizindikiro za mavuto zomwe ndiyenera kudziwa ndi ziti?

Kodi pali kusiyana kotani pakati pa matenda a chiwindi a Polycystic (PCLD) ndi matenda a Caroli?

Matenda a chiwindi a Polycystic (PCLD) ndi matenda a Caroli onse amakhudza njira zotulutsira ndulu m'chiwindi. Koma pali kusiyana kwakukulu pakati pa awiriwa. Mu PCLD, ma cysts ambiri odzaza ndi madzi amapangika m'chiwindi chonse. Izi zili ngati matumba osazolowereka. Ngakhale kuti ma cysts amathanso kupangika mu matenda a Caroli, makamaka zimakhudza kukulitsa kwa njira zapadera zotulutsira ndulu mkati mwa chiwindi.

Ndiye kodi pali ubale wotani pakati pa matenda a Caroli ndi choledochal cysts?

Matenda a Caroli amakhudza njira za bile zomwe zili mkati mwa chiwindi, zomwe ndi njira za bile zomwe zili mkati mwa chiwindi . Ma cysts omwe amapangidwa m'njira za bile zomwe zili mkati mwa chiwindi ndi mtundu wa choledochal cyst . Chifukwa chake, ngati muli ndi ma cysts angapo, amatchedwa matenda a Caroli. Mwachidule, matenda a Caroli ndi mtundu wa choledochal cyst.

Pomaliza, zinthu zofunika kwambiri zomwe muyenera kukumbukira

Matenda a Caroli akhoza kukhala oopsa pang'ono kumva. Komabe, chifukwa cha kupita patsogolo kwa sayansi ya zamankhwala, tsopano pali njira zothandiza zothetsera vutoli. Mwa kuwunika nthawi zonse, inu ndi dokotala wanu mutha kuyang'anira matenda anu mosamala. Anthu ambiri omwe ali ndi matenda a Caroli amapeza mpumulo ku zizindikiro zawo ndi mankhwala , ndiNjira zachipatala nthawi zambiri zimakhala njira yabwino kwambiri, zomwe zikutanthauza kuti palibe mabala akuluakulu.

Kumbukirani, cholinga chachikulu apa ndi kukhala wathanzi komanso wochita masewera olimbitsa thupi kwa nthawi yayitali momwe mungathere. Chifukwa chake, musachite mantha, ingotsatirani malangizo a dokotala wanu mosamala. Musaope kufunsa mafunso ngati muli nawo.

Matenda a Caroli , Chiwindi, Matumbo a Bile, Matenda a Majini, Jaundice, Miyala ya Gallstone