Tiyeni tiphunzire zambiri zokhudza kuchotsedwa kwa mankhwala, mankhwala ochizira khansa omwe amalamulidwa ndi mahomoni.

N'zovuta kufotokoza mantha ndi nkhawa zomwe timamva tikadziwa kuti tili ndi khansa. Koma chifukwa cha sayansi yapamwamba ya zamankhwala yomwe yabwera kwa ife lero, pali mankhwala othandiza kwambiri a khansa. Kodi mukudziwa, pali mitundu ina ya khansa yomwe imakula mwa "kudyetsa" mankhwala a thupi lathu otchedwa mahomoni? Pochiza khansa yotereyi, kuwongolera kupanga mahomoni amenewo ndikofunikira kwambiri. Lero tikambirana za chithandizo chapadera chotere. Dzinalo ndi 'Chemical Castration'. Ngakhale dzinalo lingamveke ngati loopsa pang'ono, kwenikweni ndi mankhwala omwe amabweretsa mpumulo kwa odwala ambiri a khansa.

Mwachidule, kodi Chemical Castration ndi chiyani?

Chabwino, tiyeni tifotokoze izi mosavuta. 'Chemical Castration' ndi kugwiritsa ntchito mankhwala kapena mankhwala kuti aletse kupanga mahomoni ogonana m'thupi lathu. Mahomoni awa amatulutsidwa m'magazi ndi tiziwalo tosiyanasiyana m'thupi lathu. Mahomoni awa amalamulira zinthu zambiri m'thupi lathu; zinthu monga mphamvu, kukula, ndi malingaliro. Mahomoni ogonana ndi ofunikira kwambiri pazinthu monga kutha msinkhu ndi thanzi lobereka.

Komabe, mitundu ina ya khansa, monga khansa ya prostate ndi mitundu ina ya khansa ya m'mawere, imadalira mahomoni ogonana awa kuti akule. Monga momwe chomera chimafunikira madzi kuti chikule, maselo a khansa awa amafunikira mahomoni kuti akule. Chifukwa chake, Chemical Castration treatment imachepetsa kuchuluka kwa mahomoni ogonana awa m'thupi. Kenako maselo a khansa amataya "chakudya" chomwe amafunikira, ndipo kukula kwawo kumayima kapena kuchedwa.

Pali mayina ena angapo omwe amagwiritsidwa ntchito pa chithandizochi. Mukawamva, izi zidzamveka bwino kwa inu:

• Kutaya Mankhwala
• Chithandizo cha Mahomoni
• Chithandizo cha Androgen Depression/Deprivation/Subpression

Mayina onsewa amatanthauza chinthu chimodzi: amachepetsa kuchuluka kwa mahomoni ogonana m'thupi.

Kodi mankhwalawa amagwiritsidwa ntchito pa matenda otani?

Madokotala amagwiritsa ntchito kwambiri mankhwalawa pa zotupa zomwe zimadalira mahomoni ogonana, makamaka:

• Khansa ya Prostate: Khansa iyi mwa amuna nthawi zambiri imayamba chifukwa cha testosterone ya mahomoni a amuna.
• Khansa ya m'mawere: Mahomoni achikazi otchedwa estrogen ndi progesterone amakhudza kukula kwa mitundu ina ya khansa ya m'mawere mwa akazi.
• Khansa ya m'mawere ya amuna: Ngakhale kuti izi sizichitika kawirikawiri, mankhwala a mahomoni amagwiritsidwanso ntchito pa izi.

Dzina lina lodziwika bwino la mahomoni ogonana ndi androgens.Aliyense amapanga ma androgens, koma amuna amapanga ambiri. Testosterone ndi androgen yayikulu. Homoni iyi ndi yofunika kwambiri pakukula ndi kugwira ntchito kwa prostate gland. Khansa ikachitika, homoni iyi ndi yomwe imayambitsa khansa kukula.

Kodi chimachitika ndi chiyani chithandizo chisanayambe?

Dokotala wanu asanakulimbikitseni chithandizo cha mahomoni, ayenera kudziwa bwino ngati khansa yanu iyankha bwino. Izi zidzafuna mayeso angapo. Mayesowa amatha kudziwa mtundu wa khansa komanso momwe yafalikira.

Mayeso ena omwe amachitika pachifukwa ichi ndi awa:

• Kujambula kwa CT
• Kujambula kwa PET
• Endoscopy
• Kufufuza za khansa - Kutenga chitsanzo cha maselo a khansa kuti akaonedwe.
• Kuyezetsa magazi kwa khansa

Nthawi zina, makamaka ngati mukufuna kuchepetsa testosterone yanu kwamuyaya, dokotala wanu angakuuzeni za opaleshoni yotchedwa orchiectomy . Izi zimaphatikizapo kuchotsa tchire limodzi kapena onse awiri mwa opaleshoni. Iyi ndi njira yokhazikika. Njira ina ndi opaleshoni yochotsera minofu yokha yomwe imapanga testosterone. Komabe, zomwe tikulankhula pano ndi kudulidwa kwa mankhwala, osati opaleshoni. Ndi chithandizo cha kanthawi kochepa ndi mankhwala.

Kodi chimachitika ndi chiyani panthawi ya chithandizo?

Iyi si njira yochizira kamodzi kokha. Iyi ndi njira yopitilira. Nthawi zambiri, dokotala wanu amakupatsirani mankhwala awa ngati jakisoni kapena ngati kachipangizo kakang'ono komwe kamayikidwa pansi pa khungu lanu (implant). Komabe, mankhwala ena amapezekanso ngati mapiritsi.

Kutengera mtundu ndi mlingo wa mankhwala omwe mwapatsidwa, mungafunike kubwereza chithandizochi kamodzi pamwezi, kamodzi pa miyezi itatu iliyonse, kapena kamodzi pachaka.

Pochiza khansa ya prostate, pali njira zingapo zomwe mankhwalawa amagwirira ntchito:

• Amachepetsa kupanga kwa androgens (makamaka testosterone) kuchokera m'machende.
• Zimalepheretsa mphamvu ya androgens m'thupi kuti igwirizane ndi maselo a khansa.
• Zimaletsa kupanga ma androgens kuchokera ku ziwalo zina za thupi (osati ma testicles okha).

Ndi mankhwala ati omwe amagwiritsidwa ntchito pa izi?

Pali mitundu ingapo ya mankhwala omwe amagwiritsidwa ntchito pa khansa ya prostate. Tiyeni tiwone bwino.

Kodi njira iyi imagwiritsidwanso ntchito pa khansa ya m'mawere?

Inde. Madokotala amalimbikitsanso chithandizo cha mahomoni ichi cha khansa ya m'mawere chomwe chimadalira estrogen ndi/kapena progesterone. Chimagwira ntchito poletsa kupanga mahomoni achikazi kapena kuwaletsa kugwira ntchito pa maselo a khansa. Palinso mitundu yosiyanasiyana ya mankhwala a izi:

• Mankhwala monga Tamoxifen amagwira ntchito poletsa hormone ya estrogen kuti isamamatire ku maselo a khansa.
• Mankhwala oletsa aromatase (monga Anastrozole, Letrozole) amagwira ntchito poletsa enzyme yomwe imapanga estrogen m'thupi.
• Mankhwala monga Goserelin ndi Leuprolide (omwe amagwiritsidwanso ntchito pa khansa ya prostate) amaletsa mazira kugwira ntchito kwakanthawi ndikuchepetsa kupanga kwa estrogen. Izi zili ngati kusamba kwakanthawi.

Kodi mungayembekezere chiyani mutalandira chithandizo?

Mankhwalawa amayamba kugwira ntchito mukangoyamba kuwamwa. Amakhala ndi mphamvu bola mukawamwa.

Zotsatira zake zazikulu ndi kuchepa kwa chilakolako chogonana/libido. Kuyankha ku zolimbikitsa zamaganizo kapena zakuthupi kungachepe. Mwachitsanzo, kuchuluka kwa malingaliro okhudza kugonana kungachepe.

Mukasiya kulandira chithandizo, thupi lanu limayambanso kupanga mahomoni. Pamodzi ndi izi, chilakolako chanu chogonana chimabwerera pamlingo wake wakale. Uwu ndiye ubwino waukulu kuposa kuchotsa machende kapena mazira obereketsa opaleshoni.

Kodi pali zoopsa zilizonse ndi zotsatirapo zake pa chithandizochi?

Monga mankhwala ena aliwonse, chithandizo cha mahomoni chingakhale ndi zotsatirapo zake. Si aliyense amene amalandira zonsezi. Ndipo kuopsa kwa zotsatirapo zake kumasiyana malinga ndi munthu. Dokotala wanu adzakuuzani za zotsatirapo zake za mankhwala omwe mukumwa.

Kawirikawiri, izi ndi zina mwa zotsatira zoyipa zomwe zingachitike mukatenga chithandizochi kwa nthawi yayitali:

• Chilakolako chochepa chogonana
• Kumva kutentha mwadzidzidzi m'thupi (Kutentha kwambiri)
• Matenda a mafupa
• Kuchepetsa minofu
• Kuchuluka kwa mafuta m'thupi
• Kuwonjezeka kwa chiopsezo cha matenda a mtima
• Kuvutika maganizo kapena kusintha kwa maganizo
• Kuchepa kwa magazi m'thupi
• Tsitsi lochepa la thupi
• Matenda a m'mawere ang'onoang'ono mwa amuna

Musachite mantha ndi zotsatirapo zake. Zambiri mwa izo zitha kuthetsedwa. Mwachitsanzo, dokotala wanu angakulangizeni kuti mugwiritse ntchito calcium ndi vitamini D komanso kuchita masewera olimbitsa thupi kuti muchepetse kufooka kwa mafupa. Chifukwa chake ndikofunikira kudziwitsa dokotala wanu za vuto lililonse lomwe mukukumana nalo.

Mafunso ena omwe amafunsidwa kawirikawiri

Kodi iyi ndi mankhwala opweteka?

Ngati mumwa mankhwala ngati piritsi, palibe ululu. Ngati mumwa ngati jakisoni, mungamve kupweteka pang'ono kapena kutentha pamene jakisoniyo waperekedwa. Koma nthawi zambiri sizikhala nthawi yayitali.

Kodi n'zotheka kukhala ndi mbewa pambuyo pa chithandizo?

Inde, chilakolako cha kugonana chingachitike. Koma chifukwa cha chilakolako chochepa cha kugonana, sichingachitike kawirikawiri monga kale. Ndipo mtundu wa chilakolakocho ungasinthenso.

• Sizili zolimba monga kale
• Kulephera kusunga nthawi yayitali
• Kuchepa kwa kuchuluka kwa zochitika

Kodi vasectomy ndi mtundu wina wa kuchotsedwa kwa chiberekero?

Ayi. Ayi konse. Vasectomy ndi njira yolerera. Imangoletsa umuna kutuluka mu mbolo ndi umuna. Sizimakhudza kuchuluka kwa mahomoni anu, chilakolako chogonana, kapena ntchito yogonana.