Kodi mwamvapo za khansa yosowa kwambiri yotchedwa Chordoma? Tiyeni tikambirane za iyo!

Mwina simunamvepo dzina lakuti "chordoma" kale. Sizodabwitsa, chifukwa uwu ndi mtundu wa khansa wosowa kwambiri. Komabe, ngakhale kuti ndi wosowa, ndikofunikira kwambiri kudziwa izi. Chifukwa, mtundu uwu wa chotupa ukhoza kuchitika msana wathu kapena pansi pa chigaza. Chifukwa chake lero, tiyeni tikambirane mwatsatanetsatane komanso mwachidule za chordoma iyi, momwe imakulira, zizindikiro zake, komanso mankhwala ake.

Kodi Chordoma ndi chiyani? Tiyeni tipeze yankho mosavuta!

Mwachidule, chordoma ndi chotupa cha khansa chomwe chimapangika m'mafupa . Nthawi zambiri chimakula msana wanu kapena pansi pa chigaza chanu, mafupa pamwamba pa khosi lanu ndi pansi pa ubongo wanu. Madokotala amachiika ngati mtundu wa khansa wotchedwa sarcoma. Sarcoma ndi mawu ofala a khansa yomwe imapangika m'mafupa ndi minofu yofewa (minofu yolumikizana).

Ma chordoma nthawi zambiri amakula pang'onopang'ono . Komabe, vuto ndilakuti amatha kukhala ovuta kuwachiza chifukwa amakhala pafupi kwambiri ndi dongosolo lathu la mitsempha, kutanthauza ubongo ndi msana, ndipo amalowa m'maselo ofooka ozungulira.

Chinanso n'chakuti ngakhale mutalandira chithandizo, zotupazi zimakhala ndi mwayi waukulu wobwereranso . Nthawi zambiri, izi zimachitika pamalo omwewo pomwe chotupa choyambirira chinali. Komanso, pa 30% mpaka 40% ya milandu, maselo a khansa ya chordoma amatha kufalikira ku ziwalo zina za thupi. Madokotala amatcha izi "metastasizing".

Kodi Chordoma ingafalikire kuti ku ziwalo zina za thupi?

Ngati chordoma yafalikira, kutanthauza kuti, yafalikira ku ziwalo zina za thupi, malo omwe imapezeka kwambiri ndi awa:

• Mapapu anu
• Ma lymph nodes pafupi ndi chotupa
• Mafupa ena
• Chiwindi
• Khungu

Kodi chordoma ingayambire kuti?

Chordoma ikhoza kuchitika kulikonse pamsana wanu, koma pali malo atatu ofala kwambiri:

1. Sacrum: Iyi ndi fupa la makona atatu pakati pa matako anu. Pafupifupi 35% ya ma chordomas amakula apa.

2. Maziko a chigaza: Makamaka, pansi pa chigaza chanu, m'mafupa omwe amathandizira ubongo wanu. Izi zimatchedwanso ``Clival chordomas'' chifukwa nthawi zambiri zimapangidwa mu fupa la ``Clivus'', lomwe lili pano. Mtundu uwu umaphatikizaponso pafupifupi 35% ya ma chordomas onse.

3. Mu mafupa oyenda a msana (`vertebrae`): Ndiko kuti, mafupa ozungulira khosi, pachifuwa, ndi kumbuyo kwanu. Ma chordoma amapezeka pafupifupi 30% mwa awa. Amapezeka kwambiri mu mafupa achiwiri a msana. Amapezekanso m'mafupa ozungulira msana (lumbar spine) ndi pachifuwa (thoracic spine).

Kodi mitundu ikuluikulu ya chordoma ndi iti?

Bungwe la World Health Organization (WHO) lagawa chordoma m'magulu atatu akuluakulu. Magulu amenewa amachokera ku momwe maselo a khansa amaonekera pogwiritsa ntchito maikulosikopu (histology).

1. Chordoma yachikhalidwe/yachizolowezi: Iyi ndi mtundu wofala kwambiri (80% mpaka 90% ya ma chordoma onse). Maselo amtunduwu ndi mtundu wapadera wa selo womwe umawoneka ngati "thovu" pang'ono. Chordoma ya Chondroid ndi mtundu wina wa mtundu uwu. Imakhala pakati pa 5% ndi 15% ya ma chordoma onse. Chordoma ya Chondroid nthawi zambiri imapezeka pansi pa chigaza.

2. Chordoma yosiyana: Iyi ndi mtundu wosowa kwambiri (wosakwana 5%). Umadziwika ndi kusakanikirana kosazolowereka kwa maselo. Mtundu uwu umakula mofulumira, umakhala waukali kwambiri, ndipo umatha kufalikira ku ziwalo zina za thupi kuposa mitundu ina.

3. Chordoma yosasiyana bwino: Ichinso ndi chosowa kwambiri . Odwala osakwana 60 alembedwa m'mabuku azachipatala mpaka pano. Chinthu chapadera cha mtundu uwu ndichakuti jini yotchedwa `(SMARCB1)` kapena `(INI1)` sigwira ntchito (kuchotsedwa). Mtundu uwu wa chordoma nthawi zambiri umapezeka mwa ana ndi achinyamata.

Ndani amene ali ndi mwayi waukulu wopeza chordoma?

Chordoma imatha kuchitika pa msinkhu uliwonse, mwa aliyense. Komabe, imapezeka kwambiri mwa akuluakulu azaka zapakati pa 50 ndi 80. Ana amakhudzidwa ndi milandu yochepa chabe, pafupifupi 5% ya milandu yonse.

Zapezekanso kuti amuna ali ndi mwayi wochuluka wopeza chordoma nthawi 1.5 kuposa akazi.

Kodi izi ndizofala bwanji?

Chordoma ndi khansa yosowa kwambiri . Imakhudza pafupifupi munthu m'modzi pa anthu miliyoni chaka chilichonse. Izi zikutanthauza kuti, mwachitsanzo, ku United States, milandu yatsopano pafupifupi 300 yokha ndi yomwe imapezeka chaka chilichonse.

Ma chordoma amakhala pakati pa 1% ndi 4% ya zotupa zonse zoyambirira za mafupa.

Kodi zizindikiro za chordoma ndi ziti?

Pamene chordoma ikukula, imatha kukakamiza msana kapena ubongo wozungulira. Kupanikizika kumeneku kumayambitsa zizindikiro . Zizindikiro zimathanso kusiyana malinga ndi komwe chotupacho chili mumsana.

Zizindikiro zodziwika bwino za chordoma ndi monga kupweteka, kufooka, ndi/kapena dzanzi kumbuyo, manja, kapena miyendo .

Makhalidwe a chordoma ya chigaza:

Ngati muli ndi chordoma pansi pa chigaza chanu, chomwe chili pansi pa ubongo wanu, mutha kuwona zizindikiro monga:

• Kuona kawiri (Diplopia)
• Maso osawoneka bwino
• Mutu
• Kusanza kapena kupweteka pankhope

Zizindikiro za chordoma mu tailbone/sacrum:

Ngati muli ndi chordoma pansi pa msana wanu, pafupi ndi sacrum, mutha kuwona zizindikiro monga:

• Chotupa kapena chotupa chomwe chimatuluka pakhungu
• Kuvuta kukodza kapena kutsuka (kusagwira bwino ntchito kwa chikhodzodzo kapena matumbo)
• Ululu m'munsi mwa msana kapena m'matako

Kumbukirani kuti nthawi zina zizindikirozi zimatha kusokonezedwa ndi matenda ena ofala. Ndicho chifukwa chake ndikofunikira kufunafuna upangiri wa dokotala ngati muli ndi zizindikiro zosazolowereka komanso zachilendo.

N’chifukwa chiyani matenda a Chordoma amayamba? Kodi zimayambitsa chiyani?

Ofufuza sakudziwabe chomwe chimayambitsa chordoma, koma amakhulupirira kuti kusintha kwa majini otchedwa TBXT kumakhudzidwa.

Pakhala malipoti akuti mabanja angapo ali ndi chordoma. Atawayesa, adapezeka kuti adalandira cholowa cha jini ya `(TBXT)`. Komanso, kusintha kwa jini ya `(TBXT)` kwapezeka mwa anthu omwe ali ndi chordoma koma palibe aliyense m'banjamo amene ali ndi matendawa.

Chordoma imayamba kuchokera ku maselo omwe ali mu kapangidwe kotchedwa ``notochord``. ``Notochord`` iyi ndi kapangidwe kakanthawi kochepa komwe ndikofunikira kwambiri pakukula kwa msana wa mwana wosabadwayo akamakula. Nthawi zambiri, ``notochord`` iyi imatha pafupifupi milungu isanu ndi itatu ya mimba. Komabe, mwa anthu ochepa kwambiri, ena mwa maselo a ``notochord`` awa akhoza kukhalabe m'mafupa a msana kapena pansi pa chigaza.

Kotero, lingaliro lomwe lilipo pano ndilakuti ngati pakhala kusintha kwa jini ya `(TBXT)` yomwe yatchulidwa kale, maselo otsalawa a `(notochord)` angayambe kukula modabwitsa ndikupanga chordoma.

Komanso, anthu omwe ali ndi vuto la majini lotchedwa ``Tuberous sclerosis`` ali pachiwopsezo chachikulu chotenga chordoma. Vuto la ``Tuberous sclerosis`` limeneli lingayambitse khunyu, kuchedwa kukula, komanso zotupa m'magawo osiyanasiyana a thupi. Izi zimachitika chifukwa cha kusintha kwa majini awiri otchedwa ``TSC1`` ndi ``TSC2``.

Kodi mungazindikire bwanji chordoma?

Ngati muli ndi zizindikiro za chordoma, dokotala adzakufunsani kaye za zizindikiro zanu ndi mbiri yanu yachipatala. Kenako adzakuyezani thupi lanu ndi kuyeza mitsempha.

Ngati dokotala akukayikira kuti pali chotupa, adzalamula kuti apimidwe chithunzi monga X-ray, computed tomography (CT), kapena MRI scan. MRI scan iyi nthawi zambiri imathandiza pozindikira chordoma.

Kenako, dokotala wanu angakutumizireni kwa katswiri wa khansa ya mafupa kuti akatsimikizire matendawa ndikupeza lingaliro lachiwiri. Angapangenso mayeso ena owunikira kuti adziwe komwe kuli chordoma, kuwona ngati yafalikira mbali zina za thupi, ndikuchita mayeso ena.

Komabe, njira yokhayo yodziwira chordoma ndikuchita biopsy . Izi zimaphatikizapo kutenga chitsanzo chaching'ono cha chotupacho, nthawi zambiri pogwiritsa ntchito singano biopsy, ndikuchiyang'ana pansi pa maikulosikopu. Pokhapokha katswiri angadziwe ngati ndi chordoma.

Kodi mankhwala a Chordoma ndi otani?

Chithandizo chachikulu komanso chabwino kwambiri cha chordoma ndikuchotsa chotupa chonse kudzera mu opaleshoni . Madokotala amatcha ichi ``En bloc resection``. Ngati chotupacho chachotsedwa kwathunthu mwanjira iyi, wodwalayo ali ndi mwayi wabwino kwambiri wokhala ndi moyo kwa nthawi yayitali.

Komabe, kutengera komwe zotupazo zili, izi zitha kukhala zovuta kwambiri. Makamaka, nthawi zambiri sizingatheke kuchotsa kwathunthu ma chordoma omwe ali pansi pa chigaza.

Chifukwa chordoma yomwe ili m'msana ingawononge msana wanu ndi mitsempha yofunika kwambiri komanso mitsempha yamagazi yozungulira. Ngati izi zawonongeka panthawi ya opaleshoni, zingayambitse chilema cha nthawi yayitali kapena imfa. Komanso, chordoma yomwe ili pansi pa chigaza ndi yovuta kuichotsa kwathunthu chifukwa ili pafupi kwambiri ndi ubongo, mitsempha ya cranial, ndi msana. Madokotala a mitsempha amayesa kuchotsa chotupa chochuluka momwe angathere, pomwe ali otetezeka momwe angathere.

Ma chordoma nthawi zambiri sagwira bwino ntchito ngati chithandizo chachikulu cha radiation therapy kapena chemotherapy. Komabe, pambuyo pa opaleshoni, gulu lanu lachipatala lingakulangizeni kuti mugwiritse ntchito radiation therapy kuti chotupacho chisabwererenso.

Ofufuza panopa akufufuza njira zatsopano zochizira matenda a chordoma, monga chithandizo cholunjika ndi chithandizo cha chitetezo chamthupi. Pakhoza kukhala mayesero azachipatala omwe mungatenge nawo mbali.

Kodi chordoma ingapewedwe?

Kunena zoona, palibe chomwe mungachite kuti mulepheretse kukula kwa ma chordoma. Nthawi zambiri, amakula mwachisawawa.

Komabe, ngati wina m'banja mwanu wakhala ndi Chordoma, kapena ngati muli ndi vuto lotchedwa "Tuberous sclerosis," ndikofunikira kuti mupite kwa dokotala nthawi zonse kuti akakuwoneni. Kenako akhoza kukuyang'anirani ngati muli ndi zizindikiro za Chordoma. Izi zikadziwika msanga, chithandizocho chidzakhala chopambana.

Kodi mwayi wochira ku chordoma ndi wotani? (Zomwe zingachitike ndi matenda a chordoma)

Kuneneratu, kapena chiyembekezo, cha chordoma kumadalira zinthu zingapo:

• Malo omwe chotupacho chili ndi kuchuluka kwa chotupacho chomwe chingachotsedwe mwa opaleshoni: Ngati chotupacho chingachotsedwe kwathunthu, mwayi wochira ndi waukulu. Ngati njira zina zothandizira popanda opaleshoni zigwiritsidwa ntchito, mwayi ndi wochepa.
• Kaya khansa yafalikira ku ziwalo zina za thupi (yomwe yafalikira): Ngati yafalikira kumadera akutali, kuchuluka kwa anthu opulumuka kungachepe.
• Zaka zanu mukapezeka ndi matendawa: Kawirikawiri, kuchuluka kwa anthu opulumuka kumakhala kotsika pang'ono kwa anthu azaka zopitilira 60.
• Kaya chotupacho chachotsedwa kapena ayi: Mitundu ngati ``Chordoma yosasiyanitsidwa bwino`` ili ndi chiyembekezo choipa kuposa ``chordoma wamba``.

Gulu lanu lachipatala lingakupatseni chidziwitso cholondola kwambiri cha zomwe mungayembekezere kutengera matenda anu, choncho musaope kuwafunsa mafunso.

Kodi izi zingakhale zoopsa?

Inde, chordoma imatha kupha. Nthawi zambiri, imfa imachitika chotupa chikabwereranso, zomwe zimawononga minofu ya msana, ubongo, kapena ubongo.

Kafukufuku wa odwala 357 a chordoma adapeza kuti kuchuluka kwa omwe akupulumuka matendawa kunali motere:

• Patatha zaka zitatu: 80.5%
• Patatha zaka zisanu: 68.4%
• Patatha zaka khumi: 39.2%

Koma kumbukirani, izi ndi ziwerengero chabe. Gulu lanu lachipatala lingapereke zambiri zokhudzana ndi kuchuluka kwa anthu omwe akupulumuka kutengera momwe zinthu zilili.

Kodi Khansa ya Chordoma kapena Chotupa Chachibadwa?

Chordoma ndi yoopsa kwambiri (khansa). Palibe mtundu uliwonse wa matenda ake womwe umaonedwa kuti si khansa.

Kodi ndiyenera kupita kwa dokotala liti?

Chordoma ikhoza kubwereranso ngakhale mutalandira chithandizo, ngakhale patapita zaka zambiri. Chifukwa chake, kutsatira nthawi yayitali ndi gulu lanu lachipatala ndikofunikira kwambiri.

Ngati mukupeza zizindikiro zatsopano, kapena ngati zizindikiro zomwe muli nazo zikuipiraipira , onetsetsani kuti mwalankhula ndi dokotala wanu.

Pomaliza, zinthu zingapo zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Ndizachibadwa kumva mantha komanso kupsinjika maganizo ukadziwa kuti uli ndi khansa ya m'mafupa yosowa kwambiri. Chordoma ndi khansa yomwe ndi yovuta kuchiza chifukwa cha komwe ili.

Komabe, khulupirirani kuti gulu lanu lachipatala lidzapanga dongosolo la chithandizo chatsatanetsatane lomwe lingakonzedwe bwino kwa inu ndipo lidzakuthandizani kuchiza chordoma yanu ndikukweza moyo wanu .

• Ndikofunikira kuzindikira zizindikiro msanga: funsani upangiri kwa dokotala ngati muli ndi ululu wosatha, dzanzi, kapena kusintha kwa masomphenya.
• Funani upangiri wa akatswiri azachipatala: Popeza chordoma ndi matenda osowa kwambiri, ndikofunikira kwambiri kufunafuna chithandizo kuchokera kwa gulu lachipatala lodziwa bwino ntchito.
• Kuyezetsa nthawi zonse n'kofunika ngakhale mutalandira chithandizo: Popeza pali chiopsezo choti matendawa abwererenso, pitani kukayezetsa malinga ndi malangizo a madokotala.

Ndikukhulupirira kuti izi zikuthandizani. Ngati muli ndi mafunso aliwonse, musazengereze kufunsa dokotala wanu.

` Chordoma, khansa, khansa ya mafupa, msana, chigaza, sacrum, clivus