Kodi chitetezo cha thupi lanu chafooka? Tiyeni tiphunzire za agranulocytosis.

Kodi nthawi zambiri mumadwala chimfine ndi fuluwenza ndipo mumamva kudwala kwambiri? Nthawi zina, ngakhale matenda ang'onoang'ono amatha kukhala aakulu ndipo amatenga nthawi yayitali kuti achire? Chifukwa chachikulu cha izi chingakhale kufooka kwa chitetezo cha mthupi lanu, ndiko kuti, gulu lankhondo lomwe limatiteteza ku matenda. Lero tikulankhula za vuto lomwe lingaganiziridwe nthawi ngati zimenezi, lomwe lingakhale loopsa pang'ono, koma lingathe kuchiritsidwa.

Mwachidule, kodi Agranulocytosis ndi chiyani?

Agranulocytosis (yotchulidwa: "a-gra-nu-lo-cy-to-sis") ndi vuto lomwe limayambitsa imfa pomwe chiwerengero cha ma neutrophils, mtundu wa maselo oyera amagazi, m'magazi athu chimachepa kwambiri.

Tangoganizani kuti thupi lathu lili ngati dziko. Ndiye maselo oyera ndi gulu lankhondo lomwe limateteza dzikolo. Pali magulu osiyanasiyana ankhondo m'gululi. Pakati pawo , ma neutrophils ndi gulu lapadera la ma commando lomwe limapita kukaukira majeremusi akangowaona . Choncho chiwerengero cha ma commando awa chikachepa kwambiri, ngakhale kachilombo kakang'ono kochokera kunja kangaukire thupi lathu mosavuta ndikutidwalitsa.

Matendawa angapangitse kuti mukhale ndi matenda aakulu, ngakhale ochokera ku majeremusi omwe nthawi zambiri samativulaza.

Ndiye kusiyana kotani pakati pa Neutropenia ndi Agranulocytosis?

Mwina munamvapo mawu akuti neutropenia. Ngakhale kuti mawu awiriwa amamveka ofanana, pali kusiyana pang'ono.

• Neutropenia: Matenda aliwonse omwe chiwerengero cha ma neutrophils chimakhala chochepa kuposa chachibadwa.
• Agranulocytosis: Iyi ndi njira yoopsa kwambiri komanso yoopsa ya neutropenia.

Mwachidule, pamene kuchuluka kwa neutrophil kutsika kwambiri, timatcha Agranulocytosis.

Kodi zifukwa zomwe zimayambitsa vutoli ndi ziti?

Agranulocytosis imatha kuchitika m'njira ziwiri zazikulu.

1. Agranulocytosis Yobadwa Nayo: Izi zimachitika chifukwa cha vuto la majini omwe amapanga ma neutrophils. Izi sizichitika kawirikawiri ndipo zimapezeka kwambiri mwa makanda aang'ono ndi ana.

2. Acquired Agranulocytosis: Iyi ndi mtundu wofala kwambiri. Pakhoza kukhala zifukwa zingapo zomwe zimayambitsa izi. Koma pafupifupi 70% ya milandu, ndi zotsatira zoyipa za mankhwala ena omwe timamwa. Mtundu uwu ndi wofala kwambiri pakati pa akuluakulu.

Zifukwa zazikulu za agranulocytosis yotsatira

• Mankhwala ena: Matendawa angayambitsidwe ndi mankhwala monga maantibayotiki ena, mankhwala a matenda amisala (monga clozapine), ndi mankhwala a matenda a chithokomiro (monga methimazole).
• Chemotherapy: Maselo a khansa akawonongeka, ma neutrophils, omwe ndi maselo athanzi omwe amagawikana mofulumira, amathanso kuwonongeka.
• Matenda a Autoimmune: Izi zimachitika pamene chitetezo chamthupi lathu chimachita zinthu molakwika ndikuukira maselo ake athanzi. Zitsanzo zake ndi matenda monga Lupus ndi Rheumatoid Arthritis.
• Matenda a Bone Morrow: Bone morrow ndi fakitale yomwe imapanga maselo athu onse a magazi. Chifukwa chake, matenda omwe amakhudza fakitale iyi, monga khansa monga leukemia kapena aplastic anemia, amatha kusokoneza kupanga kwa neutrophil.
• Matenda ena: Matendawa angayambitsidwenso ndi matenda oopsa monga malungo ndi chifuwa chachikulu.
• Kusowa zakudya: Chiwopsezochi chimakhalansopo chifukwa cha kusowa kwa michere yambiri monga vitamini B12 ndi folate kwa nthawi yayitali.
• Mankhwala owopsa: Kumeza mankhwala owopsa monga lead kapena mercury.

Kodi zizindikiro za agranulocytosis ndi ziti?

Chifukwa cha kuchuluka kwa ma neutrophil ochepa, zizindikiro zazikulu za matendawa ndi za matenda . Izi zimatha kuwonekera mwadzidzidzi kapena kukula pang'onopang'ono.

Zinthu zazikulu zomwe zimawonekera ndi izi:

• Kumva kuzizira kwambiri, kunjenjemera, komanso kutentha thupi .
• Kuwonjezeka kwa kugunda kwa mtima ndi kupuma.
• Kumva kutopa ndi kufooka m'thupi komwe kunalibepo kale .
• Kupweteka pakhosi, kutupa ndi kutuluka magazi m'kamwa.
• Kuvuta kumeza chakudya chifukwa cha zilonda mkamwa ndi pakhosi .
• Kutsika mwadzidzidzi kwa kuthamanga kwa magazi (hypotension) zomwe zimapangitsa kuti munthu azimva kukomoka komanso chizungulire.

Kodi dokotala amazindikira bwanji vutoli?

Ngati muli ndi zizindikiro zilizonse zomwe zatchulidwa pamwambapa, makamaka ngati muli ndi matenda opatsirana pafupipafupi, dokotala adzakuyesani. Kuyezetsa kofunikira kwambiri kuti mudziwe ngati muli ndi vutoli ndi kuwerengera magazi kwathunthu (CBC) . Nthawi zina timatchanso kuwerengera magazi kwathunthu (FBC).

Kuyeza kumeneku kumayesa chiwerengero chenicheni cha ma neutrophils m'magazi anu. Ngati chiwerengero cha ma neutrophils chili chochepera 100 pa microliter iliyonse, chimapezeka kuti ndi Agranulocytosis.

Kuphatikiza apo, dokotala angafunenso kuyitanitsa mayeso ena kuti apeze chomwe chikuyambitsa vutoli.

• Kufufuza Mafupa a M'mafupa: Kuyesa kumeneku kumachitika kuti aone ngati pali vuto lililonse mu mafupa a m'mafupa, fakitale yomwe imapanga maselo a magazi.
• Kuyezetsa Majini: Ngati pali kukayikira kuti iyi ndi vuto lobadwa nalo, mutha kutumizidwa kukayezetsa.

Kodi mankhwala a agranulocytosis ndi ati?

Ngakhale kuti vutoli ndi loopsa, nkhani yabwino ndi yakuti pali njira zothandiza zochiritsira vutoli. Chithandizocho chimadalira chomwe chikuyambitsa vutoli.

• Kusiya mankhwala omwe amayambitsa vutoli: Ngati chifukwa chake ndi mankhwala omwe mukumwa, chinthu choyamba komanso chofunikira kwambiri choti muchite ndikusiya kumwa. Komabe, musasiye kumwa mankhwala anu nokha. Onetsetsani kuti mwalankhula ndi dokotala wanu ndikutsatira malangizo ake kuti muchite zimenezo mosamala.

• Mankhwala Opha Majeremusi: Ngati muli kale ndi matenda m'thupi lanu, dokotala wanu adzakupatsani mankhwala amphamvu opha majeremusi kuti muthane nawo.

• Jakisoni wa G-CSF: Izi zimatchedwa Granulocyte Colony-Stimulating Factor (G-CSF). Jakisoniyu amalimbitsa mafupa ndipo amathandiza kuti apange maselo a neutrophil mwachangu.

• Mankhwala Oletsa Kutupa kwa Thupi: Ngati chifukwa chake ndi matenda odziteteza okha, mankhwala monga prednisone angaperekedwe kuti athetse chitetezo cha mthupi chomwe chimagwira ntchito mopitirira muyeso.

• Kusamutsa Mafupa: Ngati njira zina zothandizira sizikuyenda bwino, kusamutsa mafupa kuchokera kwa munthu wathanzi kungathe kuchitidwa ngati njira yomaliza.

Kodi ndingadziteteze bwanji ku matenda panthawi ya chithandizo?

Ndikofunikira kwambiri kupewa matenda opatsirana pochiza munthu amene ali ndi vutoli.

• Sambani m'manja mwanu nthawi zonse ndi sopo.
• Chepetsani kupita ku malo odzaza anthu momwe mungathere.
• Valani chophimba nkhope mukatuluka.
• Idyani chakudya chophikidwa bwino komanso choyera chokha.

Kodi n'zotheka kuchira kwathunthu ku vutoli?

Inde, nthawi zambiri zimakhala zotheka. Nthawi yochira imadalira chifukwa chake.

Ngati chifukwa chake ndi mankhwala, kuchuluka kwa ma neutrophil nthawi zambiri kumabwerera mwakale mkati mwa milungu 1 mpaka 3 mutasiya kumwa mankhwalawo.

Ngati matendawa atapezeka ndi kuchiritsidwa msanga, matendawa amatha kuthetsedwa kwathunthu. Komabe, ngati sanalandire chithandizo, angayambitse matenda oopsa komanso matenda oopsa monga sepsis . Anthu opitirira zaka 65 komanso omwe ali ndi matenda ena a mtima, impso, kapena mapapo ali pachiwopsezo chachikulu cha mavuto.