Kodi nthawi zina mumaganiza kuti, "Mulungu wanga, n’chifukwa chiyani ndikukalamba mofulumira chonchi?" Kapena nkhope yanu yayamba kuoneka yozungulira ndipo mafuta pang'ono aonekera kumbuyo kwa khosi lanu? Mwinanso mumamva kutopa komanso chizungulire nthawi zonse. Ngati muli ndi chimodzi mwa zizindikirozi, chifukwa chake chingakhale kusintha kwa kuchuluka kwa mahomoni otchedwa cortisol m'thupi lanu. Kotero lero, tiyeni tikambirane za cortisol ndi mayeso omwe amayesa mwatsatanetsatane, mosavuta.
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Mwachidule, kodi cortisol ndi chiyani?
Cortisol ndi homoni yofunika kwambiri m'thupi lathu. Ganizirani kuti ndi homoni yaikulu ya "kuyankha kupsinjika" m'thupi lathu. Tikapanikizika kapena kupsinjika, cortisol ndi yomwe imakonzekeretsa thupi lathu kuthana nayo. Kuphatikiza apo, homoni iyi imathandizira pa ntchito zina zambiri zofunika m'thupi lathu.
- Amalamulira kuthamanga kwa magazi.
- Zimathandiza kusunga shuga m'magazi.
- Zakudya za carbohydrate, mapuloteni, ndi mafuta zomwe zili m'zakudya zomwe timadya zimatithandiza kuzisintha kukhala mphamvu.
- Amalamulira kutupa m'thupi.
- Zimathandizanso ndi kayendedwe ka kugona ndi kudzuka komwe kumalamulira kugona kwathu ndi kudzuka kwathu.
Homoni ya cortisol iyi imapangidwa ndi tiziwalo tiwiri tating'ono tomwe tili pamwamba pa impso zathu. Timatcha tiziwalo timeneti kuti adrenal glands. Chifukwa chake ngati pali vuto ndi tiziwalo timeneti, kapena ndi pituitary gland pansi pa ubongo, kuchuluka kwa cortisol kumatha kukhala kokwera kwambiri kapena kotsika kwambiri. Ngati dokotala wanu akukufunsani za zizindikiro izi, angakufunseni kuti muyesedwe ndi cortisol.
Kodi zizindikiro za cortisol yokwera ndi yotsika ndi ziti?
Pamene kuchuluka kwa cortisol kumasintha, thupi lathu limatumiza zizindikiro zosiyanasiyana. Tiyeni tiwone zizindikirozi. Ndikuwonetsani izi patebulo kuti mumvetse mosavuta.
| Pamene kuchuluka kwa cortisol kuli kokwera (High Cortisol) | Pamene kuchuluka kwa cortisol kumatsika (Cortisol Yotsika) |
|---|---|
| Kulemera mofulumira (makamaka m'mimba, pachifuwa, ndi pankhope) | Kutopa kosalekeza |
| Nkhope yozungulira | Chizungulire |
| Kupangika kwa chotupa chonenepa kumbuyo kwa khosi kapena pakati pa mapewa | Kuchepetsa thupi |
| Kuthamanga kwa magazi | Kuthamanga kwa magazi kotsika |
| Kuchuluka kwa shuga m'magazi | Kufooka kwa minofu |
| Kusintha kwa khungu (kupsa mosavuta, mizere yofiirira) | Kusanza, nseru, ndi kupweteka m'mimba |
| Kusamba kosakhazikika kwa akazi | Kulakalaka mchere m'thupi |
Kodi ndi zifukwa ziti zomwe zimapangitsa kuti cortisol ichuluke?
Ngati kuchuluka kwa cortisol kuli kokwera kwambiri, timatcha vutolo kuti Cushing's syndrome . Pakhoza kukhala zifukwa zingapo zazikulu zomwe zimapangitsa izi:
- Kumwa mankhwala ambiri a steroid (monga prednisone) kwa nthawi yayitali pa matenda ena.
- Chotupa mu pituitary gland muubongo. Gland iyi ndi yomwe "imalamulira" ma gland ena.
- Chotupa mu adrenal glands.
Kodi ndi zinthu ziti zomwe zimayambitsa kuchepa kwa cortisol m'thupi?
Vuto lalikulu lomwe limayambitsa kuchepa kwa cortisol ndi matenda a Addison . Apa ndi pamene chitetezo chathu cha mthupi chimaukira tiziwalo ta adrenal. Kuphatikiza apo,
- Matenda kapena kuwonongeka kwa adrenal glands.
- Pituitary gland sikugwira ntchito bwino.
- Kusiya mwadzidzidzi kumwa mankhwala a steroid omwe akhala akugwiritsidwa ntchito kwa nthawi yayitali.
Chofunika: Ngati mukugwiritsa ntchito mankhwala aliwonse a steroid, musasiye kumwa mwadzidzidzi popanda upangiri wa dokotala.Kuchita zimenezi kungayambitse kuchepa kwa cortisol mwadzidzidzi, zomwe zimapangitsa kuti pakhale ngozi.
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Check Availability →Kodi mayeso a cortisol amachitidwa bwanji?
Pali njira zitatu zazikulu zoyezera kuchuluka kwa cortisol m'magazi mwanu: kuyezetsa magazi, malovu, ndi mkodzo. Dokotala wanu adzakupatsani mayeso oyenera kwambiri kutengera zizindikiro zanu.
Milingo ya Cortisol nthawi zambiri imasinthasintha tsiku lonse, ndipo kuchuluka kwake kumakhala kwakukulu m'mawa kwambiri komanso kotsika kwambiri pakati pausiku . Ichi ndichifukwa chake mayeso ena amafunika kuchitidwa nthawi zina za tsiku.
1. Kuyesa Magazi a Cortisol
Iyi ndi njira yodziwika kwambiri yoyezera. Nthawi zambiri imachitika kawiri patsiku.
- Choyamba: pafupifupi 8 koloko m'mawa (pamene kuchuluka kwa cortisol kumakhala kwakukulu)
- Chachiwiri: Pafupifupi 4pm (pamene kuchuluka kwa cortisol kumatsika)
Ndi zophweka kwambiri. Labu imangotenga magazi ochepa kuchokera mumtsempha womwe uli m'dzanja lanu.
2. Kuyesa kwa Cortisol Saliva
Iyi ndi njira yolondola komanso yosavuta. Izi ndizofunikira kwambiri pozindikira matenda a Cushing. Dokotala adzakupatsani kachidutswa kakang'ono ka mankhwala.
- Izi nthawi zambiri zimachitika pakati pa 11 ndi 12 koloko madzulo , asanagone. Izi zili choncho chifukwa nthawi imeneyi ndi pamene kuchuluka kwa cortisol m'thupi la munthu wathanzi kumakhala kotsika kwambiri. Ngati kuchulukako kukadali kwakukulu panthawiyo, ndi chizindikiro cha vuto.
- Muyenera kupewa kudya, kumwa, kapena kutsuka mano anu mphindi 30 musanayesedwe.
- Muyenera kugwira swab mkamwa mwanu kwa mphindi ziwiri kuti mutenge malovu, kenako muyibwezeretse mu chubu ndikuitumiza ku labotale.
3. Kuyesa Mkodzo wa Cortisol
Nthawi zina dokotala wanu angakupempheni kuti mutenge mkodzo wanu kwa maola 24.
- Chomwe chimachitika pamenepa ndichakuti muyenera kusonkhanitsa chitsanzo cha mkodzo uliwonse womwe mumamwa kwa maola 24 mu botolo lapadera lomwe mumapatsidwa.
- Botolo ili liyenera kusungidwa nthawi zonse mufiriji kapena m'bokosi lokhala ndi ayezi.
- Maola 24 akatha, ayenera kutumizidwa ku labu.
Ndi mayeso ena apadera ati omwe amachitidwa?
Nthawi zina, kuyezetsa kwina kumafunika kuti mupeze chifukwa chenicheni cha kuchuluka kwa cortisol m'magazi anu.
- Mayeso Olimbikitsa ACTH: Izi zimayesa momwe ma adrenal glands anu amayankhira ku mahomoni otchedwa ACTH, omwe amachokera ku pituitary gland. Izi nthawi zambiri zimachitika pamene kuchuluka kwa cortisol kuli kochepa.
- Mayeso Ochepetsa Dexamethasone: Izi zili ngati mbali ina ya mayeso omwe ali pamwambapa. Amachitidwa kuti apeze chomwe chimayambitsa kuchuluka kwa cortisol m'magazi. Apa, mankhwala ochepa otchedwa Dexamethasone amaperekedwa, ndipo kuchuluka kwa cortisol kumayesedwa m'mawa wotsatira.
Kutengera ndi zotsatira za mayesowa, dokotala wanu amatha kudziwa ngati vuto lili mu pituitary gland, adrenal gland, kapena china chilichonse. Nthawi zina, ngati mukukayikira kuti pali chotupa , mungapemphe CT scan kapena MRI scan .
Kumbukirani, kuchuluka kwa cortisol kosazolowereka pa lipoti la mayeso si nthawi zonse chizindikiro cha matenda aakulu. Kuchuluka kwa cortisol kumatha kusinthanso chifukwa cha zinthu monga kupsinjika maganizo kwambiri, kuchita masewera olimbitsa thupi, mimba, ndi mankhwala ena.
Uthenga Wopita Nawo Kunyumba
- Cortisol ndi mahomoni omwe amalamulira kupsinjika m'thupi lathu ndipo amachita ntchito zina zofunika kwambiri.
- Zizindikiro monga kunenepa mwadzidzidzi, kutopa, ndi chizungulire zimatha kuchitika chifukwa cha kusintha kwa kuchuluka kwa cortisol m'thupi.
- Milingo ya Cortisol imatha kuyezedwa kudzera mu mayeso a magazi, malovu, kapena mkodzo. Milingo yake imasiyana malinga ndi nthawi ya tsiku.
- Ngati kuchuluka kwa cortisol kuli kokwera kwambiri, kungakhale chizindikiro cha matenda a Cushing , ndipo ngati kuli kotsika kwambiri, kungakhale chizindikiro cha matenda a Addison .
- Ngati muli ndi zizindikiro izi kapena mukuda nkhawa ndi zotsatira za mayeso anu, onetsetsani kuti mwalankhula ndi dokotala wanu . Pewani kudziyesa nokha komanso kudzipatsa chithandizo.
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