Ngati inu kapena wina m'banja mwanu ali ndi matenda a sickle cell, simuyenera kulankhula za ululu woopsa womwe umabwera nawo, sichoncho? Ululu womwe umachokera m'mafupa a thupi kupita pachifuwa ndi wovuta kuufotokoza m'mawu. Pali nthawi zambiri zomwe simungathe kuchita chilichonse tsiku lililonse ndipo muyenera kuthamangira kuchipatala. Pali nthawi zina pamene vutoli lapangitsa moyo kukhala wovuta. Komabe, ndi kupita patsogolo kwa sayansi ya zamankhwala, mankhwala atsopano abwera omwe amabweretsa mpumulo kwa odwala otere. Chiyembekezo chimodzi chatsopano ndi katemera wotchedwa Crizanlizumab. Tiyeni tikambirane za izi lero.
Mwachidule, kodi Crizanlizumab ndi chiyani?
Crizanlizumab (yotchulidwa kuti Krizan-li-soo-mab) ndi katemera wapadera womwe umaperekedwa kuti uchepetse zizindikiro za anthu omwe ali ndi matenda a sickle cell . Dzina lake ndi ADAKVEO .
Taganizirani izi motere: mitsempha yamagazi m'matupi athu ili ngati misewu. Maselo ofiira amagazi ali ngati magalimoto omwe amanyamula mpweya m'misewu iyi. Maselo ofiira a munthu wathanzi ndi ozungulira komanso osalala, kotero amayenda mosavuta m'mitsempha yamagazi osakodwa.
Koma maselo ofiira a magazi a munthu amene ali ndi matenda a sickle cell ndi osiyana pang'ono. Amapindika kukhala ngati sickle (C shape) ndipo amakhala ndi mtundu womata. Chifukwa cha izi, maselowa amamatirana mkati mwa mitsempha yamagazi, amalumikizana, ndikuletsa kuyenda kwa magazi. Zili ngati kuchuluka kwa magalimoto pamene magalimoto ambiri amamatirana pamsewu. Pamene kuyenda kwa magazi kutsekedwa motere, mpweya umachepa m'malo osiyanasiyana a thupi. Pamenepo ndi pamene ululu wosapiririka umabwera. Timatcha izi kuti ndi vuto la ululu . Nthawi zina vutoli likachitika pachifuwa, limatchedwa Acute Chest Syndrome , lomwe ndi vuto loopsa kwambiri.
Katemera wa Crizanlizumab amaletsa maselo omata kuti asagwirizane. Izi zikutanthauza kuti, amachepetsa kuchuluka kwa magazi m'mitsempha yamagazi. Kenako magazi amayenda bwino , ndipo thupi limalandira mpweya womwe limafunikira. Izi zitha kuchepetsa kwambiri kuchuluka kwa ululu waukulu.
Izi ndi za gulu la mankhwala otchedwa monoclonal antibodies . Izi zikutanthauza kuti, puloteni yomwe idapangidwa mwapadera mu labotale, monga ziwalo za chitetezo chamthupi lathu. Imapita mwachindunji kukayang'ana ndikuyimitsa njira yomwe imapangitsa maselo amenewo kumamatirana.
Zinthu zomwe muyenera kuuza dokotala wanu musanamwe mankhwalawa
Musanayambe chithandizochi, ndikofunikira kwambiri kuuza dokotala wanu mbiri yonse ya thanzi lanu. Onetsetsani kuti mwawauza izi:
- Zokhudza ziwengo zanu: Ngati muli ndi ziwengo zilizonse zokhudzana ndi crizanlizumab, mankhwala ena aliwonse, chakudya, utoto, kapena zosungira, chonde tidziwitseni kaye.
- Ngati muli ndi pakati kapena mukufuna kutenga mimba:Sizikudziwika bwino momwe mankhwalawa angakhudzire mwana panthawi ya mimba. Chifukwa chake, ngati muli ndi pakati kapena mukukonzekera kukhala ndi mwana posachedwa, muyenera kukambirana izi ndi dokotala wanu.
- Ngati ndinu mayi woyamwitsa: Pali chidziwitso chochepa chokhudza ngati mankhwalawa amalowa mu mkaka wa m'mawere. Chifukwa chake, ngati ndinu mayi woyamwitsa, ndi bwino kukambirana ndi dokotala wanu za ubwino ndi zoopsa za chithandizo musanapange chisankho.
Kodi katemera amaperekedwa bwanji?
Iyi si mankhwala omwe mungapite nawo kunyumba. Katemera wa crizanlizumab amaperekedwa kuchipatala kapena ku chipatala ndi ogwira ntchito zachipatala ophunzitsidwa bwino.
- Katemera amaperekedwa m'mitsempha . Izi nthawi zambiri zimatenga pafupifupi mphindi 30.
- Matenda anu adzayang'aniridwa mosamala ndi ogwira ntchito zachipatala panthawi ya chithandizo komanso kwa nthawi yayitali mutalandira chithandizo, chifukwa anthu ena angakumane ndi zotsatirapo zoyipa akalandira katemera.
- Mankhwalawa nthawi zambiri amaperekedwa kwa anthu azaka 16 kapena kuposerapo . Ngati aperekedwa kwa ana osakwana zaka zimenezo, chisamaliro chapadera chiyenera kuperekedwa. Dokotala wanu ndiye adzasankha.
Chofunika kwambiri: Mankhwalawa aperekedwa kwa inu nokha. Musagawane mankhwalawa ndi wina aliyense pazifukwa zilizonse.
Kodi mungachite chiyani ngati mwamwa mopitirira muyeso?
Popeza izi zimaperekedwa kuchipatala, chiopsezo chogwiritsa ntchito mankhwala mopitirira muyeso n'chochepa kwambiri. Komabe, ngati mukuganiza kuti mwakumanapo ndi vuto ngati limeneli, imbani National Poisons Information Centre ku National Hospital nthawi yomweyo. Kapena pitani ku Emergency Department (ETU) ya chipatala chapafupi.
Nanga bwanji ngati nditaphonya tsiku lomwe ndiyenera kumwa mankhwalawo?
Ndikofunikira kwambiri kuti chithandizochi chikhale chopambana kuti mumwe mankhwalawo pa masiku omwe mwakonza komanso nthawi zomwe mwakonza. Musaphonye nthawi yanu yokumana ndi dokotala, kutanthauza tsiku lomwe mwauzidwa kuti mubwere kudzalandira mankhwalawo.
Ngati simungathe kubwera tsiku limenelo pazifukwa zina zadzidzidzi, chonde imbani dokotala wanu kapena chipatala nthawi yomweyo ndipo muwadziwitse. Adzakudziwitsani tsiku lotsatira.
Kodi zotsatirapo zake zingakhale zotani chifukwa cha mankhwalawa?
Monga mankhwala ena aliwonse, anthu ena amatha kukhala ndi zotsatirapo zoyipa akalandira katemera wa Crizanlizumab. Koma si aliyense amene amapeza zonse. Zina zimakhala zazing'ono ndipo zimatha pakatha masiku ochepa. Koma pali zinthu zina zomwe tiyenera kudziwa.
Izi zitha kumveka bwino kuchokera patebulo lomwe lili pansipa.
| Mtundu wa zotsatira zoyipa | Zizindikiro zomwe muyenera kuziganizira |
|---|---|
| Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala wanu nthawi yomweyo | |
| Matenda a ziwengo | Kutupa pakhungu, kuyabwa, kutupa kwa nkhope, milomo, lilime kapena pakhosi. |
| Kuyankha kwa Kulowetsedwa | Kupweteka pachifuwa, kuvutika kupuma, chizungulire, kapena kukomoka. |
| Zotsatirapo zomwe nthawi zambiri sizili zoopsa, koma ziyenera kufotokozedwa kwa dokotala ngati zikupitirira | |
| Kupweteka kwa thupi | Kupweteka kwa msana, kupweteka kwa mafupa. |
| Zina mwazinthu | Malungo, mutu, nseru, kupweteka m'mimba. |
Mndandandawu suli ndi zotsatirapo zonse zomwe zingachitike. Ngati muwona china chake chachilendo kuwonjezera pa izi, lankhulani ndi dokotala wanu za izi.
Kodi pangakhale mavuto ndi mankhwala ena?
Malinga ndi zomwe zikudziwika pakadali pano, palibe malipoti omwe akusonyeza kuti katemera wa Crizanlizumab wayambitsa kuyanjana kwakukulu ndi mankhwala ena.
Komabe, sizikutanthauza kuti simuyenera kuuza dokotala wanu za mankhwala onse omwe mumamwa.
Perekani dokotala wanu mndandanda wathunthu wa zonse zomwe mumatenga:
- Mankhwala operekedwa ndi madokotala a matenda ena
- Mankhwala monga ochepetsa ululu omwe mumagula ku pharmacy.
- Mavitamini, mankhwala achikhalidwe, mankhwala a Ayurvedic kapena zowonjezera zina
- Komanso, tiuzeni ngati mumasuta fodya, mumamwa mowa, kapena mumagwiritsa ntchito mankhwala ena osokoneza bongo.
Zinthu zina zingagwirizane ndi mankhwala m'njira zomwe sitikuyembekezera. Choncho chitetezo chanu chiyenera kukhala chomveka bwino pa chilichonse.
Uthenga Wopita Nawo Kunyumba
- Crizanlizumab ndi katemera wapadera womwe umaperekedwa kuti uchepetse kupweteka kwambiri komanso mavuto ena omwe amayamba chifukwa cha matenda a sickle cell.
- Mankhwalawa amaletsa maselo ofiira a magazi kuti asamamatire pamodzi ndi kusonkhana pamodzi mkati mwa mitsempha ya magazi.
- Uwu ndi mankhwala operekedwa kudzera m'mitsempha kuchipatala kapena ku chipatala. Sangagwiritsidwe ntchito kunyumba.
- Musanayambe chithandizo, uzani dokotala wanu za ziwengo zanu zonse, kaya muli ndi pakati kapena mukuyamwitsa, komanso mankhwala ena onse omwe mukumwa.
- Musaphonye nthawi yokumana ndi dokotala. Ngati simungathe kufika, chonde dziwitsani dokotala pasadakhale.
- Ngati mukukumana ndi zizindikiro zoopsa monga kupuma movutikira, kupweteka pachifuwa, kapena kutupa pankhope panthawi ya katemera kapena mutalandira katemera, funsani upangiri wa dokotala nthawi yomweyo.
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