Kodi pali malo achilendo pakhungu lanu? Akhoza kukhala DFSP (Dermatofibrosarcoma Protuberans)!

Kodi mwaonapo kachiphuphu kakang'ono kapena kusintha kwa mtundu pakhungu lanu? Nthawi zina sitimachiyang'anira kwambiri, eti? Koma nthawi zina ngakhale chinthu chaching'ono ngati ichi chingakhale chinthu chodetsa nkhawa nacho. Lero, tikambirana za mtundu wa khansa ya pakhungu wosowa koma wofunikira. Umatchedwa Dermatofibrosarcoma Protuberans , kapena DFSP mwachidule.

Kodi DFSP (Dermatofibrosarcoma Protuberans) ndi chiyani?

Mwachidule, DFSP ndi khansa ya pakhungu yomwe ikukula pang'onopang'ono, koma yosowa kwambiri. Imayamba pakati pa khungu lathu, dermis . Mungamvenso dokotala akuitcha DFSP.

Popeza khansa iyi ikukula pang'onopang'ono, nthawi zambiri imafalikira ku ziwalo zina za thupi. Komabe, si bwino kuinyalanyaza. Ndikofunikira kwambiri kupeza chithandizo choyenera ndikuchotsa chotupachi. Pokhapokha khansayo ingalepheretsedwe kubwereranso (kubwereranso) kapena kufalikira ku ziwalo zina za thupi (khansa yofalikira). Ndi chithandizo choyenera, munthu amene ali ndi DFSP amakhala ndi mwayi waukulu wochira.

Kodi DFSP iyi ndi chotupa chabe? Kapena ndi khansa?

Ayi, DFSP si chotupa chosaopsa chokha. Ndi matenda oopsa . Kunena zoona, ndi mtundu wa khansa ya minofu yofewa, mtundu wa sarcoma ya minofu yofewa . Sarcomas ndi khansa yomwe imapezeka m'malo monga minofu, mafuta, ndi khungu. Nthawi zina, imathanso kukhudza mafupa.

Kodi DFSP ingafalikire (kufalikira kwa maselo) ku ziwalo zina za thupi?

Kawirikawiri DFSP si mtundu wa khansa womwe umafalikira mofulumira kwambiri m'thupi lonse. Komabe, nthawi zambiri, pafupifupi munthu m'modzi mwa anthu 20 omwe ali ndi DFSP amatha kufalikira kupitirira komwe adayambira. Izi zimatchedwa khansa yofalikira .

Izi zitha kufalikira kwambiri ngati sizikuchiritsidwa, kapena ngati khansa yafalikira kwambiri pakhungu, mpaka minofu yamafuta ndi minofu.

Chinanso n'chakuti, ngakhale kuti chifukwa chenicheni sichikudziwika, ngati DFSP ikukula panthawi ya mimba, ikhoza kukhala yoopsa kwambiri.

Komanso, anthu ochepa omwe ali ndi DFSP amatha kukhala ndi mtundu woopsa komanso wofalikira mwachangu wotchedwa fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS) . Ngakhale zotupa za DFSP-FS izi zitachotsedwa opaleshoni, zimakhala ndi mwayi wobwereranso ndipo zitha kufalikira kumadera ena.

Kodi vuto limeneli lotchedwa DFSP ndi lofala bwanji?

DFSP ndi mtundu wa khansa wosowa kwambiri. Padziko lonse lapansi, umakhudza anthu pafupifupi anayi pa anthu miliyoni pachaka. DFSP imapanga pakati pa 1% ndi 6% ya ma sarcoma onse ofewa a minofu.

Khansa iyi imapezeka kwambiri mwa akuluakulu azaka zapakati pa 20 ndi 50. Komabe, ana aang'ono amathanso kudwala khansa ya pakhungu iyi. Ana ena amatha kukhala ndi DFSP akangobadwa. Kafukufuku wasonyeza kuti anthu akuda ali ndi mwayi wochuluka wodwala khansayi kuposa anthu amitundu ina.

Kodi mitundu ikuluikulu ya ma DFSP ndi iti?

Akatswiri a matenda, madokotala omwe amafufuza minofu ya thupi pogwiritsa ntchito maikulosikopu, angakuuzeni mtundu weniweni wa DFSP yomwe muli nayo pofufuza maselo. Pali mitundu ingapo ikuluikulu:

• Matenda a Bednar (omwe amadziwikanso kuti DFSP yokhala ndi utoto): Mitundu iyi ya maselo ili ndi melanin yambiri, utoto womwe umapatsa khungu mtundu wake. Ichi ndichifukwa chake matendawa amatha kuwoneka m'mitundu yosiyanasiyana, kuphatikizapo ofiira, abulauni, abuluu, ndi ofiirira. Mtundu uwu umapanga pafupifupi 5% ya matenda a DFSP.
• Giant cell fibroblastoma: Mtundu uwu umadziwika ndi kupezeka kwa maselo akuluakulu. Mtundu uwu umatchedwanso juvenile DFSP chifukwa umapezeka kwambiri mwa ana ndi achinyamata.
• Fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS): Monga tanenera kale, iyi ndi mtundu wa sarcoma yofewa yomwe imafalikira mofulumira komanso moopsa.
• Myxoid DFSPs: Izi zimapangidwa ndi mtundu wosadziwika bwino wa minofu yolumikizana yotchedwa myxoid stroma. Mtundu uwu wa DFSP ndi wosowa kwambiri.

Kodi chimayambitsa DFSP ndi chiyani?

Chodabwitsa n'chakuti, anthu 9 mwa 10 omwe ali ndi DFSP ali ndi kusintha kwa majini komwe kumayambitsa vutoli . Kusintha kwa majini kumeneku kumachitika m'maselo athu titabadwa. Izi zikutanthauza kuti DFSP siimayamba chifukwa cha vuto la majini lochokera kwa makolo athu.

Kodi ndi zinthu ziti zomwe zimayambitsa chiopsezo cha DFSP?

Kuwonjezera pa mtundu, kuvulala kulikonse pakhungu kapena zipsera kungapangitse kuti pakhale chiopsezo chotenga DFSP. Pali njira zingapo zomwe khungu lingavulazidwire:

• Kuwotcha
• Kulandira chithandizo cha radiation
• Kucheka opaleshoni
• Zojambulajambula

Tangoganizirani, munayamba mwapsa kwambiri komanso kukhala ndi chilonda chachikulu. Kapena, munalandira chithandizo cha radiation cha matenda ena. Khungu likawonongeka ndi zinthu ngati izi, pali mwayi wochepa woti matenda ngati DFSP adzakula mtsogolo, ngakhale kuti nthawi zina sachitika kawirikawiri. Ndicho chifukwa chake nthawi zonse tiyenera kudziwa kusintha kwa khungu.

Kodi zizindikiro za DFSP ndi ziti?

Zizindikiro zoyambirira za DFSP zimakhala zosaonekera kwambiri moti sitingazione kapena kuziona. Zotupa zimenezi nthawi zambiri zimayambira pachifuwa, kumbuyo, mapewa, pamimba, kapena m'matako. Zingathenso kukula m'manja, miyendo, khungu la mutu, komanso mkamwa.

Poyamba, mungaone kachidutswa kakang'ono konga mabala pakhungu.Ndi yosalala komanso yopanda ululu. Ingamveke ngati yowuma pang'ono ikakhudza, ndipo mtundu wake ungasinthe pang'ono.

Mu makanda ndi ana aang'ono, DFSP imatha kuoneka ngati chizindikiro cha kubadwa . Madontho amenewa nthawi zambiri amakhala ndi mulifupi wa pafupifupi theka la inchi mpaka mainchesi awiri (1 mpaka 5 cm).

Zizindikiro za DFSP zimaonekera khansa ikakula. Pamene chotupacho chikukula, chimakankhira pamwamba pa khungu (epidermis). Izi zimapangitsa kuti ziphuphu zolimba (nodules) ziwonekere pamwamba pa khungu . Mawu oti "protuberance" amatanthauza "kutuluka."

Mukhoza kuona zizindikiro izi m'matumbo awa:

• Imatha kusweka kapena kutuluka magazi mosavuta.
• Imalumikizidwa mwamphamvu pakhungu (siingathe kusunthidwa).
• Pamene mukukula, khungu lanu limatambasuka.
• Zimamveka zovuta kuzikhudza, kapena ngati rabala.
• Mtundu ukhoza kukhala wofiira-bulauni, wofiirira, wabuluu, kapena wofiira.
• Zingakhale zofewa pang'ono zikakhudzidwa.

Kodi pali matenda ena omwe amayambitsa zizindikiro zofanana ndi za DFSP?

Inde, pali vuto la pakhungu losakhala khansa lotchedwa cellular dermatofibroma . Izi zitha kuwoneka zofanana kwambiri ndi DFSP, makamaka kumayambiriro kwake. Cellular dermatofibromas ndi zotupa zopanda poizoni za minofu yofewa. Zimapezeka kwambiri pamiyendo. Nthawi zina zimatha kuyabwa komanso kupweteka. Dermatofibromas zambiri sizifuna chithandizo. Komabe, ndi bwino kusasokoneza zonsezi, choncho ndi bwino kuonana ndi dokotala ngati muwona china chake chatsopano pakhungu lanu.

Kodi matenda a DFSP (Dermatofibrosarcoma Protuberans) amawapeza bwanji?

DFSP imapezedwa ndi madokotala a khungu , omwe ndi madokotala omwe ali ndi maphunziro apadera okhudza khansa ya pakhungu ndi matenda a pakhungu. Dokotala wanu ayamba kaye watenga chitsanzo chaching'ono cha chotupa cha pakhungu kapena banga ndikuchitumiza ku labu kuti akachiyese (biopsy ya pakhungu) . Chotupa chonsecho chingachotsedwe ndikutumizidwa ku labu. Akatswiri a matenda a khungu adzayang'ana minofuyo pansi pa maikulosikopu kuti awone ngati ili ndi maselo a khansa.

Ngati biopsy ya pakhungu ikutsimikizira kuti muli ndi DFSP, mungapemphedwe kuti muyesedwe ndi MRI . Izi zikuthandizani kudziwa kukula kwenikweni kwa chotupacho komanso kuzama kwake pakhungu. Izi ndizofunikira kwambiri pokonzekera chithandizo.

Kodi mankhwala a DFSP (Dermatofibrosarcoma Protuberans) ndi ati?

Chithandizo chachikulu komanso chabwino kwambiri cha DFSP ndikuchotsa chotupacho mwa opaleshoni. Madokotala a khungu nthawi zambiri amagwiritsa ntchito njira yapadera yotchedwa Mohs surgery kuti achotse zotupa za DFSP. Izi ndi zomwe zimachitika pa opaleshoni iyi:

• Choyamba, mankhwala oletsa ululu amaikidwa m'malo ochizira, kuti musamve kupweteka kulikonse.
• Kenako, dokotala amadula ndi kuchotsa chotupa cha khansa. Koma osati chotupa chokha, komanso kagawo kakang'ono ka khungu labwino lozungulira. Izi zimatchedwa malire .
• Kenako, m'mphepete (malire) a minofu yochotsedwayo amawunikidwa pansi pa maikulosikopu kuti awone ngati pali maselo ena a khansa omwe atsala.
• Ngati pali maselo a khansa m'mphepete mwake, dokotalayo adzachotsa minofu ina pamalo omwe opaleshoniyo inachitikiranso.
• Mwanjira imeneyi, kuchotsa minofu kumapitirira mpaka palibe maselo a khansa omwe amapezeka m'mphepete mwa tsinde.
• Khansa ikachotsedwa kwathunthu, opaleshoni yokonzanso mafupa imachitika ngati pakufunika kutero.

Kodi pali njira zina zochiritsira DFSP popanda opaleshoni?

Ngakhale zotupa za DFSP zitachotsedwa opaleshoni, nthawi zina zimatha kubwereranso. Pambuyo pochotsa chotupa chaching'ono, pali mwayi wa 20% mpaka 30% woti zidzabwereranso mkati mwa zaka zitatu. Pambuyo pa opaleshoni ya Mohs, chiopsezochi chimachepetsedwa kufika pa 4% mpaka 5%. Komabe, ndikofunikira kukhala maso, chifukwa zotupa zimatha kubwereranso ngakhale patatha zaka 10 kapena kuposerapo.

Nthawi zina, ngati khansa yafalikira ku ziwalo zina za thupi (metastatic DFSP), kapena ngati chotupacho ndi chachikulu kwambiri kapena chapafupi kwambiri kuti chichotsedwe mwa opaleshoni, madokotala amagwiritsa ntchito mankhwala otchedwa Imatinib . Mankhwalawa amathanso kuchepetsa chotupacho, zomwe zimapangitsa kuti chichotsedwe mosavuta mwa opaleshoni.

Komanso, ngati opaleshoni singathe kuchotsa khansa yonse, kapena ngati opaleshoniyo singatheke konse, chithandizo cha radiation chingagwiritsidwe ntchito.

Kodi chiyembekezo cha munthu amene ali ndi DFSP ndi chotani?

Nkhaniyi ndi yotonthoza kwambiri. Popeza DFSP ndi khansa yomwe ikukula pang'onopang'ono komanso yosagwira ntchito, ikalandira chithandizo choyenera, anthu opitilira 99% amakhalabe ndi moyo kwa zaka 10 kapena kuposerapo. Chifukwa chake, chofunika kwambiri ndi kusachita mantha ndikutsatira malangizo a dokotala wanu.

Kodi ndingachite chiyani kuti ndiwongolere malingaliro anga?

Pali zinthu zingapo zomwe mungachite kuti muwongolere malingaliro anu:

• Dziyezeni nokha khungu nthawi zonse. Yang'anani kusintha kulikonse, mawanga, kapena zotupa pakhungu lanu. Ngati muwona chilichonse, uzani dokotala wanu nthawi yomweyo.
• Mukalandira chithandizo, pitani kwa dokotala wanu kuti akakupimeni khungu lanu osachepera miyezi itatu kapena isanu ndi umodzi iliyonse kwa zaka zitatu zoyambirira. Kenako pitani kukapimidwa kamodzi pachaka, kapena monga momwe dokotala wanu wanenera.
• Chepetsani kukhudzana ndi dzuwa. Kuwala kwa dzuwa kochokera ku dzuwa kumawonjezera chiopsezo cha khansa zina za pakhungu. Choncho, valani mafuta oteteza khungu mukatuluka padzuwa, valani zovala zodzitetezera , ndipo chepetsani nthawi yanu panja nthawi yotentha kwambiri ya tsiku.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muwona kusintha kulikonse pakhungu lanu, makamaka ngati muli ndi chimodzi mwa izi, onetsetsani kuti mwawonana ndi dokotala:

• Matumbo kapena mawanga atsopano, kapena ziphuphu zatsopano pakhungu.
• Kusintha kwa ziphuphu, zizindikiro zobadwa nazo, zipsera zakale, kapena zojambula pakhungu.
• Ngati ziphuphu pakhungu zikutuluka magazi mosavuta.

Kumbukirani, kusintha kwa khungu nthawi zambiri sikungakhale koopsa. Komabe, kusintha kwina kungakhale chizindikiro cha khansa ya pakhungu. Choncho, ngati muli ndi kukayikira kulikonse, ndi bwino kuonana ndi dokotala kuti akuthandizeni.

Kodi ndifunse dokotala wanga chiyani?

Ngati mwapezeka ndi DFSP, mungafune kufunsa dokotala wanu mafunso monga:

• N’chifukwa chiyani ndinadwala khansa ya pakhungu iyi?
• Kodi ndili pachiwopsezo chotenga mitundu ina ya khansa ya pakhungu?
• Kodi chithandizo chabwino kwambiri kwa ine ndi chiti?
• Kodi pali chiopsezo chakuti khansa iyi ifalikire ku ziwalo zina za thupi?
• Kodi ndiyenera kubwera kangati kudzayezetsa khansa?

Kudziwa mayankho a mafunso awa kudzakuthandizani kumvetsetsa bwino vutoli ndipo kungakuthandizeni kufotokoza bwino za chithandizo chanu ndi mapulani anu amtsogolo.

Pomaliza, zinthu zoti muzikumbukira

Ngakhale kuti DFSP ndi khansa ya pakhungu yosowa kwambiri, sizingafalikire mbali zina za thupi. Komabe, chithandizo cha opaleshoni n'chofunika kuti musiye kukula. Kuzindikira msanga ndi chithandizo choyenera kungakuthandizeni kwambiri kuti muone bwino khungu lanu. Chifukwa chake, dziwani khungu lanu ndipo pitani kwa dokotala ngati muwona china chake chachilendo. Simuli nokha, ndipo pali madokotala omwe angakuthandizeni paulendowu.

DFSP , khansa ya pakhungu, khansa ya pakhungu, ziphuphu pakhungu, opaleshoni ya Mohs, zizindikiro za khansa, matenda a pakhungu