Zingamveke zachilendo kuganiza kuti ndowe za munthu wina zikugwiritsidwa ntchito pochiza matenda a munthu wina, sichoncho? Koma iyi ndi njira yothandiza kwambiri yochiritsira matenda ena akuluakulu. Lero tikambirana za njira yodabwitsa koma yofunika kwambiri yochiritsira iyi, yotchedwa fecal microbiota transplantation (FMT).
Kodi kuyika ndowe m'mimba n'chiyani?
Mwachidule, izi zimaphatikizapo kutenga chitsanzo chaching'ono cha ndowe ya munthu wathanzi ndikuyiyika m'matumbo a munthu wodwala. Izi zingamveke zosasangalatsa. Koma chitsanzo cha ndowe yathanzi chimakhala ndi tizilombo toyambitsa matenda topindulitsa mamiliyoni ambiri (microbiota). Tizilombo toyambitsa matenda tikalowetsedwa m'matumbo odwala, tingachite zodabwitsa kuti tibwezeretse thanzi lake.
Pakadali pano, madokotala ambiri amalimbikitsa chithandizochi ngati chithandizo cha matenda oopsa a mabakiteriya m'matumbo. Kuika kumeneku kumatumiza mabakiteriya ambiri abwino kuti amenyane ndi mabakiteriya oipa, omwe amayambitsa matenda m'matumbo omwe ali ndi matendawa. Mabakiteriya abwinowa akatha, dongosolo la tizilombo toyambitsa matenda (gut microbiome) mkati mwa matumbo athu limabwezeretsedwa.
Kodi izi zimagwira ntchito bwanji? Kodi chimachitika n’chiyani m’mimba mwathu?
Ganizirani za matumbo anu ngati munda wokongola. M'munda uno, muli zomera zabwino (mabakiteriya abwino) zomwe timafunikira, ndi zomera zoyipa (mabakiteriya oipa). Bola chilichonse chili bwino, munda ndi wokongola, zomwe zikutanthauza kuti tili ndi thanzi labwino.
Koma mankhwala ena omwe timamwa, makamaka maantibayotiki, matenda ena, ndi zinthu zina zimatha kupha zomera zambiri zabwino m'munda uno. Ndiye chimachitika ndi chiyani? Udzu, kapena mabakiteriya oipa, amalowa m'munda wonse ndikufalikira mwachangu. Pamenepo m'mimba mwathu mumakhala wosakhazikika ndipo timadwala.
Kubzala ndowe kuli ngati kubzalanso munda womwe wadzaza ndi udzu, kubweretsa zomera zambirimbiri zathanzi (mabakiteriya abwino). Mabakiteriya atsopano abwinowa amapikisana ndi mabakiteriya oipa, kuwaletsa, ndikubwezeretsa thanzi labwino m'matumbo.
Kodi mankhwalawa amagwiritsidwa ntchito pa matenda amtundu wanji?
Pakadali pano, njira yochizira iyi yakhala yopambana kwambiri ndipo yatsimikiziridwa kuti imachiza matenda obwerezabwereza a C. difficile (CDI), mtundu wa matenda am'mimba omwe amayamba chifukwa cha mabakiteriya a C. difficile, omwe ndi ovuta kuwathetsa ngakhale ndi maantibayotiki.Nthawi zina, pamene maantibayotiki alephera kulamulira matendawa, kuyika ndowe m'thupi kumabweretsa zotsatira zabwino modabwitsa.
Komabe, madokotala ndi asayansi amakhulupirira kuti njira yochiritsira iyi ingakhale yothandiza pa matenda ena ambiri. Chifukwa tizilombo toyambitsa matenda m'matumbo mwathu timakhudza kwambiri osati kokha m'mimba mwathu, komanso pa kagayidwe kathu ka chakudya ndi chitetezo chamthupi. Chifukwa chake, kafukufuku akuchitika kuti awone ngati ingachiritse matenda ena ambiri.
| Matenda ena omwe akufufuzidwa pa chithandizo cha kuyika chimbudzi | |
|---|---|
| Matenda a m'mimba | - Matenda a Kutupa kwa Matumbo (IBD) - "Matenda a m'mimba okwiya (IBS)" |
| Matenda a kagayidwe kachakudya | - Kunenepa kwambiri - Matenda a chiwindi - Matenda a shuga |
| Zochitika zina | - Ziwengo za chakudya - "Matenda a Autism Spectrum (ASD)" - Nkhawa ndi Kuvutika Maganizo - `Multiple Sclerosis (MS)` |
Kodi kuyika ndowe kumachitika bwanji? Kodi njira zake ndi ziti?
Pali njira zingapo zoperekera ndowe yathanzi iyi m'matumbo a wodwala. Dokotala wanu adzasankha njira yoyenera kwambiri pa vuto lanu.
| Njira yochizira | Kufotokozera kosavuta |
|---|---|
| Colonoscopy | Chubu chopyapyala chokhala ndi kamera (colonoscope) chimalowetsedwa kudzera mu anus ndikudutsa m'matumbo akulu. Kudzera mu chubuchi, madzi a ndowe amatha kubayidwa mwachindunji m'matumbo. Iyi ndi njira yomwe imagwiritsidwa ntchito kwambiri komanso yopambana. |
| Endoscopy Yapamwamba | Chitoliro (endoscope) chimayikidwa m'mimba kapena m'matumbo ang'onoang'ono kudzera pakamwa kapena mphuno. Komabe, njira iyi siigwira ntchito bwino chifukwa tizilombo toyambitsa matenda timayenera kuyenda mtunda wautali kudzera m'matumbo ang'onoang'ono tisanafike m'matumbo akuluakulu. |
| Enema | Madzi a m'mimba amalowetsedwa kudzera mu chubu chaching'ono chomwe chimalowetsedwa mu rectum. Njirayi ndi yopambana kwambiri chifukwa tizilombo toyambitsa matenda timapita mwachindunji kumatumbo akulu. Mankhwala oyamba ovomerezedwa ndi FDA ku United States, Fecal Transplant, amaperekedwa motere. |
| Kapisozi Yopaka Pakamwa | Iyi ndi njira yatsopano komanso yosavuta. Mumameza mapiritsi okhala ndi tizilombo touma komanso tozizira tomwe timatuluka m'matumbo ndi madzi. Mapiritsiwa amapangidwa kuti asasungunuke mpaka atafika m'matumbo akulu. |
Kodi chopondapo cha mankhwala awa mumachipeza kuti?
Pachifukwa ichi, ndowe zimatengedwa kuchokera kwa odzipereka athanzi kwambiri (opereka) . Asanasankhe munthu wopereka, amayesedwa motsatira njira zingapo zachipatala. Amaonetsetsa kuti palibe tizilombo toyambitsa matenda kapena majeremusi 100% mu ndowe ya munthuyo.
Pambuyo poti ndowe yatengedwa, imatumizidwa ku labu, kutsukidwa, kusakanizidwa ndi madzi monga saline, kusefedwa, ndikupangidwa kukhala madzi. Nthawi zina izi zimazizira kuti zigwiritsidwe ntchito pambuyo pake, kapena kuumitsidwa ndikupangidwa kukhala makapisozi.
Ndani amene sali woyenera kukhala wopereka chopondapo?
Izi zikupatsani lingaliro la kuchuluka kwa mayeso omwe amachitidwa munthu asanalowetsedwe m'malo mwa munthu wina. Palibe amene ali ndi zifukwa zotsatirazi amene adzasankhidwe ngati wopereka.
- Ngati mwagwiritsa ntchito maantibayotiki posachedwapa.
- Ngati pali matenda ena oopsa a bakiteriya monga `E. coli`.
- Ngati muli ndi matenda opatsirana monga matenda a chiwindi, HIV, kapena COVID-19.
- Ngati pali tizilombo toyambitsa matenda m'matumbo.
- Ngati mugwiritsa ntchito mankhwala osokoneza bongo.
- Ngati muli ndi matenda a kutupa m'matumbo (IBD) kapena matenda a autoimmune.
- Ngati wina aliyense m'banjamo ali ndi mbiri ya khansa.
Kodi ubwino ndi zoopsa za chithandizochi ndi ziti?
Ubwino waukulu
Mankhwalawa ndi othandiza 80% mpaka 95% popewa matenda opatsirana a C. diff. Ichi ndi chiyembekezo chachikulu cha matendawa, omwe akhala akufooketsa kwambiri kotero kuti ngakhale maantibayotiki alephera kuwaletsa.
Zotsatirapo ndi zoopsa zake
Kusamva bwino pang'ono kungachitike kwa tsiku limodzi kapena awiri mutalandira chithandizo.
- Kutupa m'mimba, flatulence
- Kusanza kapena kusanza
- Kupweteka m'mimba
- Malungo ndi kuzizira kwa anthu ena
Izi nthawi zambiri sizimakhala zoopsa ndipo zimatha pakatha masiku awiri.
Chiwopsezo chachikulu kwambiri ndi kuthekera, ngakhale kuti n’kosowa kwambiri, kuti kachilombo koopsa komwe kanali m’thupi la wopereka kangalowe m’thupi la wolandirayo n’kuyambitsa matenda. Koma kuti achepetse chiopsezochi, operekawo amayesedwa mosamala kwambiri ndipo zitsanzo za ndowe zimatsukidwa bwino kwambiri. Chiwopsezochi n’chochepa kwambiri ndi zinthu zovomerezeka zomwe zimagwiritsidwa ntchito masiku ano.
Ngakhale kuti chithandizochi chingamveke chachilendo, pali sayansi yambiri kumbuyo kwake. Ndi chitsanzo chabwino cha momwe tizilombo ting'onoting'ono m'thupi lathu tingakhudzire thanzi lathu. Kwa odwala omwe ali ndi C. diff, ichi ndi chithandizo chosintha moyo wawo.
Uthenga Wopita Nawo Kunyumba
- Kuika ndowe m'chimbudzi kungamveke zachilendo, koma ndi njira yothandiza kwambiri yochizira matenda oopsa monga C. diff yobwerezabwereza.
- Izi zikuphatikizapo kulowetsa 'mabakiteriya abwino' ochokera m'ndowe za munthu wathanzi m'matumbo a munthu wodwala, ndikubwezeretsa thanzi la tizilombo toyambitsa matenda mmenemo.
- Zitsanzo za ndowe zomwe zimagwiritsidwa ntchito pochiza zimayesedwa mwamphamvu kwambiri kuti zitsimikizire kuti zilibe matenda aliwonse, choncho chisamaliro chachikulu chimatengedwa pankhani ya chitetezo.
- Izi sizinthu zomwe mungachite kunyumba. Iyi ndi njira yapadera yachipatala yomwe imachitidwa kuchipatala kapena ku chipatala ndi madokotala oyenerera.
- Ngati inu kapena munthu amene mumamudziwa akudwala matenda am'mimba omwe sakhala ochiritsidwa ndi maantibayotiki, lankhulani ndi dokotala wanu za njira iyi yothandizira.
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