Kodi mungakhale ndi vuto 'losamveka' m'magazi mwanu? Tiyeni tiphunzire za Smoldering Multiple Myeloma (SMM)!

Nthawi zina, mavuto akuluakulu amatha kuchitika m'thupi mwathu popanda zizindikiro zilizonse zakunja. Mungaganize kuti, "O, zingatheke bwanji zimenezo?" Inde, zingatheke. Lero tikambirana za vuto linalake lomwe lingakule mwakachetechete, popanda kusonyeza zizindikiro zilizonse, koma likhoza kukhala khansa yoopsa mtsogolo. Madokotala amatcha izi (Smoldering Multiple Myeloma - SMM) . Mwachidule, izi zili ngati gawo loyambirira la matenda otchedwa "chronic multiple myeloma."

Kodi Smoldering Multiple Myeloma (SMM) ndi chiyani?

Mwachidule, Smoldering Multiple Myeloma ndi matenda omwe amakhudza magazi ndi mafupa anu. Izi zimatha kukhala khansa ya m'magazi yosowa kwambiri yotchedwa active Multiple Myeloma (MM) . Tsopano mwina mukudabwa kuti, "Kodi multiple myeloma iyi ndi chiyani?" Maselo a plasma ndi mtundu wa maselo oyera a magazi m'thupi lathu. Awa ndi omwe amapanga ma antibodies omwe amathandiza thupi lathu kulimbana ndi matenda. Komabe, nthawi zina maselo a plasma awa amatha kusintha n'kukhala maselo osazolowereka. Pamenepo ndi pomwe vuto lotchedwa multiple myeloma limachitika.

Kotero, SMM ndi gawo "losamveka" lisanakhale khansa yotchedwa multiple myeloma, popanda zizindikiro zilizonse. Nthawi zina zimatenga zaka kuti SMM ikhale multiple myeloma yogwira ntchito. Chodabwitsa n'chakuti, anthu ena omwe ali ndi SMM sakhala ndi active multiple myeloma. Ichi ndichifukwa chake madokotala nthawi zonse amafufuza anthu omwe ali ndi SMM kuti awone zizindikiro zoti ikhoza kusanduka khansa yogwira ntchito.

Kodi khansa (SMM) ndi yotani?

Funso ili ndi lovuta pang'ono. SMM siitengedwa ngati khansa yokha. Komabe, chifukwa imatha kukula kukhala khansa yotchedwa active multiple myeloma, imaonedwa ngati chiyambi cha khansa. Tangoganizirani kuti muli ndi malo osazolowereka pakhungu lanu, chizindikiro chobadwira. Chimenecho chingakhale chizindikiro choyamba cha khansa ya pakhungu, sichoncho? Ndicho chimene SMM ili. Zimatanthauza kuti muli ndi mwayi woti mudwale multiple myeloma. Ndicho chifukwa chake madokotala amawayang'anira anthu omwe ali ndi vutoli mosamala kwambiri .

Kodi pali matenda ena omwe amakhudza myeloma yambiri?

Inde, palinso ina. Imatchedwa Monoclonal Gammopathy of Undetermined Significance (MGUS) . Monga SMM, iyi ndi vuto lomwe lingachitike musanayambe multiple myeloma. Madokotala amaona MGUS (yomwe imatchulidwa kuti "M-gus") kukhala chiyambi cha multiple myeloma.

Kodi (SMM) imakhudza bwanji thupi langa? Kodi zizindikiro zake ndi ziti?

Chofunika apa ndi ichi: Anthu ambiri omwe ali ndi (SMM) sasonyeza zizindikiro zilizonse.Izi zikutanthauza kuti simungamve kupweteka kulikonse kapena kupweteka. Anthu ambiri amapeza kuti ali ndi SMM akamayesedwa magazi nthawi zonse pazifukwa zina. Mayeso a magazi amenewo angasonyeze kuti muli ndi mapuloteni amtundu wosadziwika bwino otchedwa mapuloteni a M , omwe amapangidwa ndi maselo a plasma osazolowereka m'thupi lanu.

Mayeso a magazi akusonyeza kuti maselo a plasma osazolowerekawa akupanga mapuloteni osazolowereka a chitetezo chamthupi (mapuloteni a M). Komanso, ngati muchita biopsy ya mafupa, madokotala amatha kuwona maselo a plasma osazolowerekawa mu mafupa. Komabe, panthawiyi ya "kufuka utsi", myeloma sikuyambitsa mavuto aliwonse m'thupi lanu, kotero anthu omwe ali ndi SMM nthawi zambiri samakhala ndi zizindikiro zilizonse.

Ndani angadwale (SMM)? Kodi iyi ndi matenda ofala?

Matendawa nthawi zambiri amakhudza anthu azaka zopitirira 60. Avereji ya zaka zomwe munthu amadwala matendawa ndi pakati pa zaka 62 ndi 67.

(SMM) si matenda ofala. Ofufuza akuti amakhudza munthu m'modzi yekha pa anthu 100,000. Komabe, multiple myeloma imakhudza anthu asanu ndi awiri okha pa anthu 100,000. Chifukwa chake, (SMM) ndi matenda osowa kwambiri.

Kodi chiopsezo cha (SMM) kukhala active multiple myeloma ndi chiyani?

Izi ndizofunikiranso kudziwa. M'zaka zisanu zoyambirira atapezeka ndi SMM, pafupifupi 10% ya anthu omwe ali ndi SMM amakhala ndi active multiple myeloma chaka chilichonse. M'zaka zisanu zikubwerazi, chiwerengero chimenecho chimatsika kufika pa 3% pachaka. Pambuyo pa zaka 10 zoyambirira, chiopsezochi chimatsika kwambiri kufika pa 1% pachaka.

Izi zikutanthauza kuti si aliyense amene ali ndi matenda a myeloma (SMM) amene angadwale matenda a myeloma yambiri. Komabe, pali chiopsezo, choncho kuyang'aniridwa ndi dokotala nthawi zonse n'kofunika kwambiri.

Kodi pali mayeso omwe anganene molondola ngati munthu adzakhala ndi myeloma yambiri?

Mwatsoka, pakadali pano palibe mayeso omwe anganene molondola ngati munthu adzakhala ndi myeloma yambiri. Madokotala ndi ofufuza akupitilizabe kusanthula kusintha kwa majini komwe kumachitika chifukwa cha myeloma yambiri ndipo akufuna kudziwa ngati munthu amene ali ndi SMM adzakhala ndi myeloma yambiri.

Kodi zifukwa za kuonekera kwa (SMM) ndi ziti?

Ofufuza akudziwa kuti maselo a plasma osazolowereka ndi zinthu zotchedwa mapuloteni a M ndi chizindikiro cha multiple myeloma (MM) ndi multiple myeloma (MM). Komabe, sakudziwabe chomwe chimayambitsa maselo abwinobwino komanso athanzi a plasma kukhala osazolowereka. Akufufuza zina zomwe zingayambitse:

• Kusintha kwa majini: Ofufuza akufufuza ngati pali mgwirizano pakati pa kusintha kwa majini ena (oncogenes - majini omwe amalimbikitsa kukula kwa maselo) ndi multiple myeloma (MM).
• Kunenepa Kwambiri: Pali kukayikira kuti mafuta ambiri m'thupi nawonso angakhale chifukwa cha zimenezi.

Kodi mungazindikire bwanji (SMM)? Ndi mayeso amtundu wanji omwe amachitidwa?

Madokotala angachite mayeso angapo kuti atsimikizire ngati muli ndi vutoli. Kumbukirani, ngati mayeso a magazi ndi/kapena mkodzo akuwonetsa zizindikiro za mapuloteni a M, chimenecho chingakhale chizindikiro choyamba choti muli ndi matenda a myeloma yambiri. Madokotala adzachita mayeso oyambira kuti aone ngati vuto lanu likupita ku matenda a myeloma yambiri. Mayesowa angaphatikizepo:

• Kuwerengera Magazi Konse (CBC): Izi zimayesa kuchuluka kwa maselo ofiira a magazi, maselo oyera a magazi, ndi ma platelet opangidwa ndi mafupa anu.
• Kuyesa kwa magazi: Izi zimayesa kuchuluka kwa creatinine (kuti muwone momwe impso zanu zikugwira ntchito), kuchuluka kwa albumin (kuti muwone momwe impso zanu ndi chiwindi chanu zikugwira ntchito), ndi kuchuluka kwa calcium (kuti muwone ngati mafupa anu atayika).
• Kuyesa kwa kuchuluka kwa immunoglobulin: Kuyesa kwa magazi kumeneku kumayesa kuchuluka kwa mapuloteni a M (mapuloteni oteteza thupi) m'magazi anu.
• Electrophoresis ndi serum immunofixation: Mayeso awa amafufuza mapuloteni a M m'magazi anu.
• Kuyezetsa mkodzo: Madokotala angakupempheni kuti mutenge mkodzo kunyumba kwa maola 24 kuti muwone ngati pali mapuloteni a M.
• X-ray: X-ray imagwiritsidwa ntchito kuona ngati pali kuwonongeka kwa mafupa chifukwa cha multiple myeloma.
• Kujambula kwa Computed Tomography (CT): Iyi ndi njira ina yowonera kuwonongeka kwa mafupa.
• Kujambula Magnetic Resonance (MRI): Kuyesa kumeneku kumagwiritsa ntchito mafunde a wailesi ndi maginito amphamvu kuti apange zithunzi zatsatanetsatane za mafupa ndi msana wanu. Kuyesa kumeneku kungagwiritsidwe ntchito kufufuza umboni wa kuwonongeka kwa mafupa koyambirira.
• Kufufuza za mafupa: Madokotala angatenge chitsanzo cha mafupa anu ndikuwunika kuti awone kuchuluka kwa maselo abwinobwino komanso osazolowereka a plasma omwe ali mmenemo. Angathenso kuyang'ana chitsanzo cha mafupa kuti awone kusintha kwa DNA yanu komwe kungayambitse khansa.

Kodi zofunikira za (SMM) ndi ziti?

Madokotala akamanena za "zofunikira," amatanthauza zotsatira za mayeso zomwe zikukwaniritsa miyezo yachipatala yofunikira kuti adziwe matenda. Zofunikira za (SMM) ndi izi:

• Kuyezetsa magazi komwe kumasonyeza kuchuluka kwa mapuloteni a M opitilira 3g/dl (magalamu atatu pa decilita imodzi ya magazi).
• Kuyezetsa mkodzo kwa maola 24 komwe kumasonyeza mamiligalamu 500 kapena kuposerapo a mapuloteni. Kapena...
• Kuyeza kwa mafupa kumasonyeza kuti maselo a m'magazi amapanga pakati pa 10% ndi 59% ya maselo onse a magazi omwe ali mu mafupa anu. Ndipo...
• Palibe zizindikiro za zilonda za mafupa zachilendo kapena kuwonongeka kwa impso komwe kungayambitsidwe ndi myeloma, kuchuluka kwa maselo m'magazi anu ndi kwabwinobwino, ndipo calcium yanu ndi yabwinobwino.

Kodi vutoli limachiritsidwa bwanji?

Pakadali pano, chithandizo chodziwika bwino cha SMM ndi "kudikira mosamala." Izi zimaphatikizapo madokotala omwe amachita mayeso nthawi zonse kuti ayang'ane kuchuluka kwa mapuloteni a M m'magazi mwanu ndi kuchuluka kwa maselo a m'magazi m'mafupa anu. Monga mlonda, akuyang'anira kuti awone ngati matendawa akukulirakulira.

Anthu ena akhoza kukhala pachiwopsezo chachikulu chotenga matenda a myeloma yambiri. Zikatero, madokotala ena angakulangizeni kuyamba kulandira chithandizo cha myeloma yambiri msanga. Ngati muli ndi matenda a myeloma yambiri (MM), dokotala wanu ndiye munthu wabwino kwambiri kukupatsani chidziwitso ndi malangizo a chithandizo chomwe mukufuna.

Kodi ndingachepetse chiopsezo cha matenda (SMM)?

Mwatsoka, pakadali pano palibe njira yodziwika yopewera kupangika kwa (SMM).

Kodi mungakhale ndi moyo wautali bwanji ndi (SMM)?

Mmene vutoli limakhudzira aliyense ndi losiyana. Anthu ena akhoza kukhala nalo koma sakhala ndi matenda a myeloma ambiri. Anthu ena amadwala matenda a myeloma ambiri miyezi kapena zaka kuchokera pamene anapezeka ndi matendawa. Ngati mukuda nkhawa ndi kukhala ndi SMM, funsani dokotala wanu zomwe mungayembekezere. Ndi anthu abwino kwambiri kukupatsani chidziwitso chapadera.

Kodi mungakhale ndi moyo wautali bwanji ndi multiple myeloma?

Izi ndi vuto kwa anthu ambiri. Pafupifupi 40% mpaka 82% ya anthu omwe ali ndi matenda a multiple myeloma amakhala ndi moyo zaka zisanu atapezeka ndi matendawa. Izi zimatengera zinthu zambiri, kuphatikizapo mtundu wa matenda ndi momwe chithandizo chimachitikira.

Kodi ndingasamalire bwanji thanzi langa?

Ngati muli ndi matenda a myeloma ambiri, simungafunike chithandizo nthawi yomweyo - kapena nthawi ina iliyonse. Dokotala wanu adzakuuzani kuti mubwere kudzaonana nthawi zonse. Izi ndizoona ngati vuto lanu lasintha kukhala matenda a myeloma ambiri. Kukhala ndi matenda a myeloma ambiri kungakhale kovutitsa maganizo komanso kochititsa nkhawa . Mungaganize kuti, "Ndikanakonda ndikanachitapo kanthu pa izi." Zimenezo n'zachibadwa. Koma pali zinthu zina zomwe mungachite kuti musamalire thanzi lanu lonse:

• Idyani zakudya zopatsa thanzi. Ngati simukudziwa bwino izi, funsani katswiri wa zakudya.
• Ngati ndinu wosuta fodya, chonde yesani kusiya.
• Pumulani mokwanira.
• Dzitetezeni ku matenda. Funsani dokotala wanu za njira zopewera matenda.
• Kuchita masewera olimbitsa thupi nthawi zonse.Koma, kambiranani ndi dokotala wanu kaye ndipo mufunseni mtundu wa masewera olimbitsa thupi oyenera kwa inu komanso kuchuluka kwa masewera olimbitsa thupi omwe muyenera kuchita. Si bwino kuchita zinthu zambiri.
• Samalaninso thanzi lanu la maganizo. Ngati mukumva chisoni kapena kupsinjika maganizo chifukwa cha vuto lanu, lankhulani ndi dokotala wanu za vutoli. Onetsetsani kuti mwawauza, makamaka ngati chisoni kapena kupsinjika maganizo kumatenga milungu yoposa iwiri kapena kusokoneza zochita zanu za tsiku ndi tsiku.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Ngati muli ndi (SMM), nayi mafunso ena omwe mungafunse dokotala wanu:

• N’chifukwa chiyani izi zinandichitikira ine?
• Kodi izi zimakhudza bwanji moyo wanga watsiku ndi tsiku?
• Kodi zimatenga nthawi yayitali bwanji kuti myeloma yambiri ikule?
• Kodi pali zizindikiro zinazake zomwe zingasonyeze matenda a myeloma ambiri, ndipo ndiyenera kuzidziwa?
• Kodi pali mankhwala oletsa vutoli (SMM) kuti lisakule n’kukhala multiple myeloma?

Pomaliza, zomwe muyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

Kusuta kwa Multiple Myeloma (SMM) ndi vuto lomwe limayamba chifukwa cha multiple myeloma (MM) isanamwalire ndi khansa. Komabe, si aliyense amene ali ndi SMM amene adzadwala active multiple myeloma. Anthu omwe ali ndi SMM nthawi zambiri amafuna kudziwa ngati adzadwala active multiple myeloma, ndipo ngati ndi choncho, liti. Mafunso amenewa ndi ovuta kuwayankha. Madokotala alibe mayankho onse.

Komabe, kafukufuku waposachedwapa akusonyeza kuti polemba kusintha kwa majini ena, n'zotheka kuneneratu pamlingo winawake ngati (SMM) idzakula kukhala multiple myeloma, ndipo ngati ndi choncho, liti.

Ngati muli ndi vutoli, funsani dokotala wanu ngati pali chidziwitso chatsopano chokhudzana ndi vuto lanu. Adzasangalala kukuthandizani. Chofunika kwambiri ndikutsatira malangizo a dokotala wanu ndikukhala olimba m'maganizo.

Myeloma Yochuluka Yotuluka, SMM, Myeloma Yochuluka, khansa, matenda a magazi, mafuta am'mafupa, mapuloteni a M, khansa ya m'magazi, maselo a plasma