Kodi muli ndi fungo lofanana ndi la nsomba? Tiyeni tiphunzire za Trimethylaminuria (TMAU)!

Nthawi zina m'miyoyo yathu, zinthu zachilendo zimachitika, sichoncho? Kodi mudamvapo za vuto lomwe thupi la munthu, thukuta, mpweya, kapena mkodzo zimanunkha ngati nsomba yoola? Zimamveka zachilendo, sichoncho? Koma, pali vuto lotere. Ili ndi vuto lomwe tikambirana lero, Trimethylaminuria, kapena `(TMAU)` mwachidule. Anthu ena amalitchanso ``Fish Odor Syndrome``.

Kodi trimethylaminuria (TMAU) ndi chiyani?

Mwachidule, trimethylaminuria (TMAU) ndi matenda a kagayidwe kachakudya . Tsopano mwina mukudabwa kuti matenda a kagayidwe kachakudya ndi chiyani. Mkati mwa matupi athu, njira zamakemikolo, kapena njira zamakagayidwe kachakudya , zimachitika kuti zisinthe chakudya chomwe timadya kukhala mphamvu ndikupanga zinthu zomwe thupi lathu limafunikira. Ma enzyme m'matupi athu amathandizira njirazi kuti zichitike bwino. Chifukwa chake, mu mkhalidwe uwu wotchedwa trimethylaminuria, chifukwa cha kusintha kwa ntchito ya enzyme inayake, mankhwala ena opangidwa m'thupi sangasweke bwino. Ichi ndichifukwa chake fungo losasangalatsa la nsomba limachokera ku thukuta, mpweya, malovu, ndi mkodzo.

Mwina munamvapo madokotala akutcha vutoli `(TMAU)` kapena `(Fish Odor Syndrome)`. Palibe mankhwala athunthu a izi pakadali pano . Koma, musadandaule. Mutha kuchepetsa zizindikirozi kwambiri mwa kusintha zomwe mumadya ndi kumwa, kugwiritsa ntchito sopo ndi mafuta enaake, komanso kuthana ndi nkhawa yanu.

Kodi mitundu ikuluikulu ya `(TMAU)` ndi iti?

Pali mitundu iwiri ikuluikulu ya trimethylaminuria:

1. Primary Trimethylaminuria : Uwu ndi mtundu wobadwa nawo . Izi zikutanthauza kuti vutoli limayamba chifukwa cha kusintha kwina (`(masinthidwe a majini)`) m'majini (`(majini)`) omwe amalandira kuchokera kwa amayi ndi abambo.

2. Trimethylaminuria yachiwiri : Izi zimachitika munthu akakula . Fungo la nsombali lingayambitsidwe ndi matenda enaake kapena zakudya zina zowonjezera.

Kodi vutoli ndi lofala bwanji?

Ndipotu, TMAU ndi vuto losowa kwambiri . Kafukufuku wina akusonyeza kuti limakhudza munthu m'modzi yekha pa anthu 200,000 mpaka 1 miliyoni padziko lonse lapansi. Komabe, akutinso akazi ali ndi mwayi wochuluka wodwala matendawa kuposa amuna.

Komabe, ofufuza ena amakhulupirira kuti pakhoza kukhala anthu ambiri omwe ali ndi `(TMAU)` kuposa momwe ziwerengerozi zikusonyezera. Chifukwa anthu ambiri amaganiza kuti izi ndi vuto la ukhondo wawo . Chifukwa chake, samauza aliyense za izi kapena kupita kwa dokotala chifukwa cha manyazi. Chifukwa chake, samapeza matenda (`(Matenda)`).

Kodi zizindikiro za trimethylaminuria ndi ziti?

Chizindikiro chachikulu komanso chodziwika bwino ndi fungo la nsomba kuchokera m'thupi, mpweya, ndi thukuta . Fungo ili nthawi zina limakhala losasangalatsa kwambiri moti limatha kupangitsa nseru. Kwa anthu ena, limathanso kutsagana ndi mpweya woipa (`(Halitosis)`) komanso fungo lamphamvu kuchokera mkodzo.

Nthawi zina, munthu amene ali ndi `(TMAU)` amamva fungo limeneli kwambiri akamatuluka thukuta kapena akamavutika maganizo. Komabe, kwa anthu ena, fungoli ndi lamphamvu kwambiri moti ngakhale atalowa m'chipinda chomwe amakhala, ataima moyang'anizana ndi kauntala m'sitolo, kapena atakhala mbali imodzi ya basi kapena sitima, ena amathabe kulimva fungolo. Tangoganizirani momwe zilili zovuta.

Kodi zifukwa za `(TMAU)` ndi ziti?

Trimethylaminuria imachitika pamene ntchito ya enzyme yotchedwa `(FMO3)` m'thupi lathu yasokonekera. `(FMO3)` imayimira Flavin- containing monooxygenase 3. Ntchito yayikulu ya enzyme iyi ndikulamulira mankhwala otchedwa `( Trimethylamine )` omwe amapangidwa m'thupi lathu. Trimethylamine iyi ndiye chifukwa cha fungo la nsomba. Trimethylamine iyi imapangidwa pamene zakudya zina zomwe timadya, mwachitsanzo, nsomba, nyemba, ndi mazira, zigayidwa.

Chomwe chimachitika nthawi zambiri ndi ichi: Pamene trimethylamine ikuchuluka m'thupi lathu, enzyme `(FMO3)` imabwera ndikuiphwanya, ndikuisintha kukhala mankhwala opanda fungo. Kenako, ngakhale kuti imadutsa kuchokera m'thupi lathu kupita m'magazi athu, siinunkhiza.

Koma, chimachitika ndi chiyani ngati enzyme ya `(FMO3)` imeneyo sigwira ntchito bwino? Trimethylamine wonunkhayo amaunjikana m'thupi lathu. Akaunjikana, pamapeto pake amatuluka mu thukuta, mpweya, malovu, ndi mkodzo, ndipo fungo longa la nsomba limatuluka. Kodi mukumvetsa?

Anthu omwe ali ndi trimethylaminuria yoyamba (`(Primary TMAU)`) amakhala ndi vutoli chifukwa amalandira makope osazolowereka a majini omwe amapanga enzyme ya `(FMO3)` (`(Abnormal FMO3 majini)`) kuchokera kwa amayi ndi abambo awo onse.

Mu trimethylaminuria yachiwiri (`(Secondary TMAU)`), enzyme yanu ya `(FMO3)` singathe kuswa trimethylamine pazifukwa zina. Izi zitha kuchitika chifukwa cha:

• Ngati muli ndi vuto la matenda, monga kulephera kwa chiwindi kapena matenda a chiwindi (virus hepatitis ), likhoza kusokoneza ntchito ya enzyme ndikulepheretsa kuti trimethylamine isagwire ntchito.
• Ngati microbiome ya m'matumbo mwanu ilibe mgwirizano, zomwe zikutanthauza kuti pali kusalingana pakati pa mabakiteriya abwino ndi oipa m'matumbo mwanu, trimethylamine yambiri ikhoza kusonkhana. Kenako enzyme (FMO3) singathe kuchotsa fungo lonselo.
• Ngati mutenga zakudya zowonjezera zomwe zili ndi choline kapena carnitine , zakudya zimenezi zimathandiza kuti trimethylamine ipangidwe.

Kodi mavuto a vutoli ndi otani?

Momwe matenda otchedwa trimethylaminuria amakhudzira moyo wanu(`(Moyo wabwino)`) ukhoza kukhala wovulaza kwambiri. Kafukufuku akusonyeza kuti anthu omwe ali ndi vutoli nthawi zambiri amapewa maubwenzi, ntchito, ndi zochitika zina chifukwa amaopa kuti ena angazindikire fungo losasangalatsa. Chifukwa cha izi, anthu omwe ali ndi vutoli amatha kukhala ndi mavuto osiyanasiyana amisala. Mwachitsanzo:

• Nkhawa
• Kuvutika maganizo
• Nkhawa ndi mantha osamveka bwino (`(Paranoia)`)

Ngakhale kuti sizichitika kawirikawiri, anthu ena omwe ali ndi TMAU adanenedwa kuti ali ndi malingaliro ofuna kudzipha (`(Makhalidwe Odzipha)`). Izi zikusonyeza momwe vutoli lingakhudzire kwambiri maganizo.

Kodi trimethylaminuria imapezeka bwanji?

Madokotala amazindikira TMAU poyesa kuchuluka kwa trimethylamine mu mkodzo wanu. Izi nthawi zambiri zimachitika kudzera mu mayeso a mkodzo . Kuphatikiza apo, dokotala wanu angakulangizeni mayeso a majini kuti adziwe ngati muli ndi mawonekedwe oyamba (monga obadwa nawo) kapena achiwiri (monga opezeka).

Kodi mankhwala a trimethylaminuria ndi ati?

Dokotala wanu angakulangizeni zinthu zosiyanasiyana kuti muchepetse zizindikiro za TMAU.

• Zakudya: Ndikofunikira kusiya zakudya zina zomwe zimapangitsa kuti thupi lipange mankhwala omwe amayambitsa vutoli (TMAU).
• Sopo ndi mafuta odzola apadera: Ndikoyenera kugwiritsa ntchito sopo ndi mafuta odzola apadera omwe amathandiza kuchepetsa fungo la nsomba pakhungu.
• Mankhwala: Nthawi zina mankhwala angalembedwenso.
• Thandizo la thanzi la maganizo: Mungalangizidwenso kuti mupeze uphungu wa zamaganizo kuti akuthandizeni kuthana ndi nkhawa zomwe zimayambitsidwa ndi vutoli.

Ndi zakudya ziti zomwe ziyenera kuchotsedwa?

Ngati muli ndi trimethylaminuria, madokotala nthawi zambiri amakuuzani kuti muchepetse kapena kupewa kwathunthu zakudya zotsatirazi:

• Nsomba ndi nsomba zina zam'madzi (makamaka nsomba za m'madzi amchere)
• Mazira (makamaka mazira a dzira)
• Chiwindi ndi ziwalo zina zamkati mwa nyama
• Masamba monga soya, nandolo, ndi lentils
• Ndiwo zamasamba zokazinga monga kabichi, broccoli, kolifulawa, ndi ziphuphu za Brussels
• Mtedza
• Mkaka ndi zinthu zopangidwa ndi mkaka (kwa ena)
• Zakudya ndi zowonjezera zakudya zomwe zili ndi choline ndi L-carnitine

Chofunika: Si aliyense amene ayenera kusiya kudya zakudya zonsezi. Ndi bwino kulankhula ndi dokotala kapena katswiri wa zakudya kuti adziwe zakudya zomwe zili zoyenera kwa inu.

Kodi mankhwala operekedwa a `(TMAU)` ndi ati?

Dokotala wanu angapereke mankhwala ngati awa kuti achepetse zizindikiro za TMAU:

• Mankhwala opha tizilombo toyambitsa matenda ndi ma probiotics : Mankhwalawa amathandiza kuchepetsa kuchuluka kwa mabakiteriya m'matumbo mwanu, motero amachepetsa kupanga trimethylamine.
• Makala opangidwa ndi mpweya : Izi zili ngati siponji. Zimayamwa trimethylamine m'thupi ndipo zimathandiza kuti ituluke mu ndowe.
• Mankhwala oletsa kuvutika maganizo ndi mankhwala oletsa nkhawa : Mankhwalawa amaperekedwa kuti athetse mavuto amisala omwe anthu ena omwe ali ndi TMAU amakumana nawo.

Dokotala wanu angakutumizireninso ku chithandizo cha matenda amisala . Kulankhula ndi katswiri wa zamaganizo kapena uphungu ndikofunikira kwambiri ngati mukuvutika ndi kudzidalira komanso mavuto okhudza mawonekedwe a thupi lanu. Chithandizo cha maganizo chingakuthandizeni kuphunzira momwe mungathanirane ndi vuto lanu komanso kuthana ndi nkhawa.

Kodi munthu amene ali ndi trimethylaminuria angayembekezere chiyani?

Trimethylaminuria ndi matenda osatha . Izi zikutanthauza kuti sangachiritsidwe kwathunthu kapena kuchira okha. Komabe, monga tafotokozera kale, pali mankhwala ndi zinthu zomwe mungachite kuti muchepetse zizindikiro za TMAU ndikuchepetsa momwe matendawa amakhudzira moyo wanu.

Kodi ndimadzisamalira bwanji ?

Kudzisamalira n'kofunika kwambiri mukakhala ndi TMAU. Nazi zinthu zina zofunika kuziganizira:

• Ukhondo wa munthu : Kugwiritsa ntchito sopo ndi mafuta odzola okhala ndi pH yotsika kungathandize kuchepetsa fungo la thupi lanu. Funsani dokotala wanu kuti ndi `(pH)` yotani yoyenera kwa inu komanso ndi zinthu ziti zomwe zili zabwino kwambiri.
• Samalani ndi zomwe mumadya : Zakudya zambiri zingapangitse trimethylaminuria kukhala yoipa kwambiri. Lankhulani ndi katswiri wa zakudya kuti akonze chakudya chanu ndi kusankha zakudya kuti mupeze michere yomwe mukufuna.
• Kuwongolera kupsinjika maganizo : Kuwonjezeka kwa kupsinjika maganizo kungapangitse zizindikiro za TMAU kuwonjezereka. Chifukwa chake, funsani dokotala wanu za njira zomwe zingakuthandizeni kuchepetsa kupsinjika maganizo. (monga kusinkhasinkha, yoga, kuchita masewera olimbitsa thupi opumira)
• Pezani chithandizo : Trimethylaminuria ndi vuto losowa kwambiri, kotero mungamve kuti ndinu nokha komanso nokha. Chifukwa chake, zingakhale zothandiza kwambiri kulumikizana ndi magulu othandizira komwe mungapeze ena omwe ali ndi vuto lomwelo .

Ndiyenera kupita liti kwa dokotala wanga?

Ngati zizindikiro zanu sizikuchepa ngakhale mutasintha zakudya zanu komanso kuchepetsa kupsinjika maganizo, onetsetsani kuti mwaonana ndi dokotala wanu. Iye angakuuzeni njira zina zochiritsira zomwe mungaganizire.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Popeza trimethylaminuria ndi matenda osazolowereka, mwina simungadziwe zambiri za matendawa. Nazi mafunso ena omwe mungafunse dokotala wanu:

• N’chifukwa chiyani ndinakumana ndi vutoli?
• Ndi mankhwala ati abwino kwambiri omwe mungandipangire?
• Kodi mungandipangire gulu lothandizira kapena pulogalamu komwe ndingapeze thandizo?

Kodi anthu omwe ali ndi trimethylaminuria angamve fungo lawo okha?

Izi ndi vuto kwa anthu ambiri. Inde, nthawi zambiri timamva fungo la thukuta lathu ndi fungo la thupi lathu, ndipo anthu omwe ali ndi `(TMAU)` amatha kununkhiza fungo lawo. Komabe, nthawi zina, akangozolowera fungo lawo, sangazindikire bwino monga ena amachitira. Komanso, si aliyense amene anganene kuti salimva fungo lake; anthu ena sangazindikire kuti matupi awo ali ndi fungo lachilendo.

Pomaliza, uthenga wofunika kwambiri

Trimethylaminuria ndi matenda omwe angapangitse munthu kukhala wopanda thandizo, osati mwakuthupi kokha, komanso m'maganizo . Ngakhale ngati sayambitsa ululu wakuthupi, angayambitse ululu waukulu ndi zipsera m'maganizo. Anthu ena omwe ali ndi vutoli amadzipatula okha ku anthu ena ndipo amayesa kukhala okhaokha, akuopa kuti adzakhala ovutitsa ena. Ngakhale atasintha zakudya zawo ndikutsatira malangizo ena, anthu ena omwe ali ndi `(TMAU)` amaona kuti akufunikabe kusunga miyoyo yawo kutali ndi ena. Mtundu uwu wa kudzipatula ku anthu ena ukhoza kukupatsani zinthu monga kuvutika maganizo ndi nkhawa.

Kumbukirani, simuli nokha . Ngati mukuvutika ndi vutoli, chonde musachite manyazi kapena kuopa kupempha thandizo kwa dokotala wanu. Angamvetse zomwe mukukumana nazo ndipo angakuuzeni za mapulogalamu ndi mautumiki omwe angakuthandizeni. Thanzi lanu la maganizo ndi lofunika kwambiri monga thanzi lanu lakuthupi. Choncho onetsetsani kuti mwaganiziranso za izi.

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