Mwina mwamvapo za insulin ya mahomoni. Dzinali limabwera kwambiri, makamaka tikamalankhula za matenda a shuga. Koma kodi mudamvapo za insulin-like growth factor-1, kapena IGF-1 mwachidule? Ndi hormone yomwe imagwirizananso ndi insulin, ndipo imagwira ntchito ngati insulin. Lero, tiyeni tikambirane za IGF-1 ndi momwe imagwirizanirana ndi matenda a shuga.
Mwachidule, kodi IGF-1 ndi chiyani?
`Insulin-like Growth Factor-1` kapena `IGF-1` ndi mahomoni ofunikira kwambiri omwe amapangidwa ndi chiwindi chathu. Chimodzi mwa ntchito zake zazikulu ndikudziwitsa mafupa ndi minofu yathu kuti "ikule bwino." Izi zikutanthauza kuti ndi yofunika kwambiri pakukula kwa thupi lathu.
Homoni iyi ndi yofanana kwambiri ndi insulin. Imakhudzanso momwe maselo athu amagwiritsira ntchito shuga, kapena shuga, m'magazi mwathu. Kotero tsopano mutha kuwona kuti pali kulumikizana kwakukulu pakati pa ziwirizi.
Kugwirizana ndi Matenda a Shuga a Mtundu wa 2
Choyamba, tiyeni tikumbukire momwe matenda a shuga amakulira. Homoni ya insulin imathandiza shuga yomwe timapeza kuchokera ku chakudya chomwe timadya kulowa m'maselo athu ndikupanga mphamvu. Taganizirani ngati insulin ili ngati kiyi, selo ili ngati chipinda, ndipo chitseko cha selo ndi loko. Chifukwa chake, kiyi iyi (insulin) ikalowetsedwa ndipo loko ikatsegulidwa, shuga imatha kulowa m'selo.
Koma nthawi zina thupi lathu siliyankha bwino insulin iyi. Timaitcha kuti insulin resistance . Ili ngati loko yotupa yomwe singatembenuzidwe ndi kiyi. Kenako kapamba wathu amayesa kupanga insulin yambiri kuti igwire ntchitoyo. Koma nthawi ina, nayonso singathe kuchita zimenezo. Zotsatira zake n'zakuti shuga sangalowe m'maselo ndikuwunjikana m'magazi. Pamapeto pake, vutoli limakhala matenda a shuga a mtundu wachiwiri .
Apa ndi pomwe `IGF-1` imayambira. Kafukufuku wapeza kuti anthu omwe ali ndi `IGF-1` yochepa ali pachiwopsezo chachikulu chotenga matenda ambiri otchedwa `Metabolic Syndrome`.
Matenda a Metabolic Syndrome si matenda amodzi okha. Ndi kuphatikiza kwa mavuto angapo azaumoyo, monga kuthamanga kwa magazi, cholesterol yambiri, ndi mafuta am'mimba. Zinthu zonsezi zikaphatikizidwa, chiopsezo chodwala matenda a mtima ndi matenda a shuga chimawonjezeka kwambiri.
Izi zikutanthauza kuti ngati milingo yanu ya IGF-1 ndi yotsika, mungakhale ndi mavuto ena omwe angayambitse matenda a shuga.
Ndiye kodi IGF-1 ingathandize matenda a shuga?
Funso limene ofufuza akuyesera kuyankha masiku ano ndi ili. Chinthu chimodzi chomwe chingathandize kudziwa izi ndi mankhwala otchedwa `mecasermin (Increlex).` Ichi ndi mankhwala opangidwa m'ma laboratories otchedwa `IGF-1`. Madokotala amagwiritsa ntchito mankhwalawa pochiza ana aang'ono omwe sakukula bwino.
Koma chimodzi mwa zotsatirapo zoyipa za mankhwalawa ndi kuchepa kwa shuga m'magazi, kutanthauza kuti, kuchitika kwa vuto lotchedwa `Hypoglycemia`. Izi zinakopa chidwi cha ofufuza. Mu kafukufuku wamtsogolo, akuluakulu omwe ali ndi matenda a shuga amtundu wa 2 atapatsidwa `IGF-1` iyi, adawonanso kuti shuga m'magazi mwawo amachepa. Kuphatikiza apo, kukana kwawo insulin kunakula kwambiri.
Koma ... izi zikadali mu gawo lofufuza. Popeza IGF-1 ndi mahomoni omwe amachita zinthu zambiri m'thupi, pali zambiri zoti aphunzire za momwe imagwirira ntchito. Pakadali pano, IGF-1 imavomerezedwa kokha pamavuto akukula mwa ana. Siinavomerezedwe ngati mankhwala a matenda a shuga.
Tidziwenso za zotsatirapo zoopsa.
`IGF-1` si chinthu choseweretsa. Ingayambitse mavuto aakulu. Ndikofunikira kwambiri kudziwa izi.
| Zotsatira zoyipa | Kufotokozera kosavuta |
|---|---|
| Kutupa mu Retina | Retina ndi gawo lomwe lili mkati mwa diso lomwe limatumiza zomwe timawona ku ubongo. Kutupa kumeneku kungayambitse kuwonongeka kwakukulu kwa masomphenya. |
| Kupweteka kwakukulu kwa minofu ndi mafupa | Pakhoza kukhala ululu wosapiririka m'minofu ndi m'malo olumikizirana mafupa a thupi. |
| Matenda a Bell's Palsy | Apa ndi pamene mbali imodzi ya nkhope imafooka mwadzidzidzi ndipo imagwa, ngati sitiroko. |
| Kuopsa kwa khansa | (Chofunika kwambiri) IGF-1 yapezeka kuti ikugwirizana ndi kukula kwa khansa ya m'mawere, m'matumbo akulu, m'mapapo, ndi m'prostate. |
Zoona zokhudza zowonjezera zakudya
Nkhani imeneyi ndi yofunika kwa anthu ambiri. Ena omanga thupi ndi othamanga amagwiritsa ntchito zowonjezera za IGF-1, kaya zogulitsidwa pamtengo wotsika kapena zoperekedwa ndi dokotala, kuti awonjezere mphamvu zawo.
Koma kumbukirani, bungwe la World Anti-Doping Agency (WADA) laletsa mitundu yonse ya mahomoni a IGF-1, kuphatikizapo zowonjezera.
WADA imati ngakhale mankhwala a `IGF-1` omwe dokotala wakupatsani akhoza kuwononga mafupa anu, chiwindi, ndi mtima wanu kwamuyaya ngati agwiritsidwa ntchito molakwika. Nanga bwanji za zakudya zowonjezera zomwe zimagulitsidwa popanda malamulo? Palibe amene akudziwa zomwe zili mkati mwake.
Ena amagwiritsa ntchito mankhwalawa pofuna kuchepetsa ukalamba kapena kuti athandize pa thanzi. N’zoona kuti pamene tikukalamba, matupi athu amapanga IGF-1 yochepa. Komabe, palibe umboni wa sayansi wosonyeza kuti kumwa mankhwala owonjezera a IGF-1 kungakuthandizeni kukhalabe achinyamata.
Lingaliro ili likuchokera ku kafukufuku wokhudza mankhwala a shuga otchedwa metformin. Mu maphunziro amenewo, nyongolotsi ndi mbewa zimakhala ndi moyo wautali zikapatsidwa metformin. Koma sizikudziwikabe momwe zingakhudzire anthu.
Choncho, ngati mukuganiza zomwa mankhwala owonjezera a `IGF-1`, chonde musaganizepo za izi. Onetsetsani kuti mwalankhula ndi dokotala wanu musanachite izi. Kulowetsa zinthu zamphamvu zotere m'thupi lanu popanda upangiri wa dokotala kungayambitse mavuto osayerekezeka.
Uthenga Wopita Nawo Kunyumba
- `IGF-1` ndi mahomoni achilengedwe ofanana ndi insulin omwe ndi ofunikira pakukula kwa thupi lathu.
- Kuchepa kwa IGF-1 m'thupi kumalumikizidwa ndi matenda a Metabolic Syndrome, omwe amawonjezera chiopsezo cha matenda a shuga ndi matenda a mtima.
- Ngakhale kuti pali kafukufuku wokhudza kugwiritsa ntchito IGF-1 ngati mankhwala a matenda a shuga, sikunavomerezedwebe.
- Homoni iyi ingayambitse mavuto aakulu monga kuwonongeka kwa maso, kupweteka kwa mafupa, komanso khansa.
- Kugwiritsa ntchito mankhwala owonjezera a `IGF-1` pamsika n'koopsa kwambiri. Akuphatikizidwanso pamndandanda wa World Anti-Doping Agency.
- Nthawi zonse funsani dokotala musanagwiritse ntchito mankhwala enaake kapena mankhwala enaake.
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