Ese hari igihe uhura n'ikibazo cyo kubyimba mu mubiri wawe gitunguranye? Bishobora kuba angioedema!

Ese wigeze ubona iminwa yawe ibyimba mu buryo butunguranye, cyangwa amaso yawe yumva abyimbye? Hari igihe isura yawe yose, ndetse n'amaboko n'ibirenge byawe, birabyimba. Ni ibisanzwe kumva ufite ubwoba gato iyo ikintu nk'iki kibaye. Akenshi, ibi biterwa n'indwara yitwa angioedema . Reka tubiganireho mu buryo burambuye, mu buryo bworoshye, sibyo?

Angioedema ni iki? Reka tubisobanukirwe mu buryo bworoshye!

Mu magambo make, Angioedema ni ukubyimba kw'imitsi iri munsi y'uruhu rwacu, cyane cyane dermis, urwego rw'imbere rw'uruhu, cyangwa ibice biri munsi y'ururabo rw'umura. Ibi bibaho nk'ingaruka ku kintu runaka. Ushobora kuba warumvise indwara yitwa urticaria , cyangwa hives . Angioedema n'ibicurane bikunze kubaho hamwe, kandi impamvu zirasa cyane. Muri ibyo bihe byombi, amazi ava mu mitsi mito y'amaraso ajya mu bice by'umubiri, bigatuma utwo duce tubyimba.

Ubusanzwe indwara ya angioedema itangira mu buryo butunguranye ikagabanuka mu munsi umwe cyangwa ibiri. Ikunze kugira ingaruka ku minwa no hafi y'amaso . Ariko, tekereza, niba iki kibyimba kigize ingaruka ku nzira z'ubuhumekero bwacu, gishobora kuba kibi cyane, ndetse kikanashyira ubuzima mu kaga . Bityo rero tugomba kwitonda kuri ibyo.

Ni ubuhe bwoko bw'ingenzi bwa angioedema?

Hari ubwoko butandukanye bwa angioedema. Imiryango itandukanye y’ubuzima ishobora kubushyira mu byiciro bitandukanye, ariko muri rusange, dushobora kumenya ubwoko bumwe na bumwe bw’ingenzi.

1. Indwara ya angioedema ikabije ya allergie

Iyi ishobora kuba ari yo ndwara wigeze kumva kandi wahuye nayo cyane. Ibaho iyo uhuye n'ikintu ufite ubwivumbure . Iyi ishobora kuba ari ikintu wariye (ibiryo, icyo kunywa), wafashe umuti, cyangwa wakozeho (urugero, ikintu gikozwe muri latex karemano). Ishobora kandi kubaho nyuma yo kurumwa n'udukoko cyangwa igitagangurirwa.

Indwara ya angioedema ikabije ibaho vuba cyane , akenshi mu minota mike kugeza ku isaha imwe cyangwa ebyiri, nyuma yo guhura n'iyo ndwara. Uku kubyimba akenshi kujyana n'uduheri.

2. Kurwara indwara ya angioedema biterwa n'uko imiti idafite allergie

Ubu bwoko bwa angioedema ntibuhita bugaragara nyuma yo gufata umuti. Ubwoko bw'imiti nyamukuru itera iyi resistance idatera allergie ni angiotensin-converting enzyme inhibitors , cyangwa ACE inhibitors cyangwa ACEIs mu magambo ahinnye.Iyi miti ikunze gukoreshwa mu kwagura imiyoboro y'amaraso, kuvura indwara z'umutima, no kugabanya umuvuduko ukabije w'amaraso. Imiti igabanya ubukana bw'amaraso idakoresha steroide (NSAIDs) , nka ibuprofen na naproxen, nayo ishobora gutera ubwo bwoko bwa angioedema.

3. Kubyimba kwa angioedema bitazwi (Idiopathic angioedema)

Ijambo " idiopathike" risobanura "impamvu itazwi." Rero biragoye kubona impamvu yihariye itera ubu bwoko bwa angioedema. Kubyimba bikunze kubaho mu maso, mu maboko, mu gituza no mu maguru. Hari abantu bashobora kandi kugira ibibazo by'ubudahangarwa bw'umubiri ndetse n'imihangayiko.

4. Ubwinshi bw'indwara ya kanseri y'uruhererekane (HAE)

Iyi ni angioedema yo mu bwoko bwa regorité , izwi kandi nka HAE mu magambo ahinnye. Iki ni ikintu uhabwa n'ababyeyi bawe binyuze mu turemangingo twawe. Abana bashobora kuyiragwa nubwo umubyeyi umwe gusa ari we ufite iyo gene, cyangwa se niba bafite iyo ndwara. Hari abantu bashobora no kugira ubu bwoko bwa angioedema bitewe n'impinduka mu buryo bwikora mu turemangingo. Bivugwa ko umuntu umwe kuri 50.000 ashobora kugira ubwo bwoko bwa angioedema yo mu bwoko bwa regorité (HAE). Hari ubwoko butatu bw'ingenzi bw'iyi ndwara, buri bumwe muri bwo bufitanye isano mu buryo runaka n'urugero rwa poroteyine ya C1 cyangwa inhibitor ya C1 esterase mu maraso yacu.

5. Kubura uburyohe bwa C1 bwo kwirinda indwara ya angioedema

Ibi kandi bitera angioedema, ariko si umurage. Acquired bivuze ko utavukanye iyo ndwara, ariko uzayirwara nyuma mu buzima. Kimwe n'izindi ndwara, iyi ndwara ishobora kugira ingaruka ku maraso yawe, cyangwa imiyoboro y'umwuka, kandi ishobora gutera kubura umwuka. Niba ufite indwara nka lymphoma ya B-cell, iyi ndwara yitwa Acquired C1 inhibitor deficiency.

6. Kubyimba kwa angioedema guterwa no guhindagura (Vibratory angioedema)

Muri iyi ndwara, kubyimba guterwa no guhindagura guhoraho. Urugero, ibi bishobora kubaho iyo utwaye moto, wiruka, wiruka, ukoze massage ikomeye, cyangwa ukoze ibindi bikorwa bisa na byo. Vibratory angioedema ni ubundi bwoko bw'indwara idakunze kugaragara yitwa chronic inducible urticaria . Muri yo, hives zigaragara bitewe n'ibintu byo hanze nk'ubukonje, ubushyuhe, amazi, igitutu, cyangwa guhindagura. Utubyimba dukomeza kandi tumarana ibyumweru bitandatu.

Ni nde ufite amahirwe menshi yo kurwara angioedema?

Mu by’ukuri, umuntu wese ashobora kugira angioedema. Bivugwa ko hagati ya 20% na 25% by’abaturage b’Abanyamerika bazagira angioedema cyangwa urticaria nibura rimwe mu buzima bwabo. Iyi ndwara rero ikunze kugaragara no muri Sri Lanka.

Ni ibihe bimenyetso bya angioedema? Ubimenya ute?

Ibimenyetso by'ingenzi bya angioedema ni ibi bikurikira:

• Kubyimba cyangwa kubyimba mu maso , cyane cyane hafi y'amaso n'umunwa, harimo n'iminwa n'ururimi. Tekereza ubyutse mu gitondo maze mu buryo butunguranye iminwa yawe irabyimba cyane ku buryo wumva bigoye kuvuga.
• Iyo amara yawe abyimbye, ushobora kugira ibibazo byo mu gifu . Ibi birimo kubabara mu gifu, impiswi, isesemi no kuruka.
• Kubyimba amaboko, ibirenge, cyangwa imyanya ndangagitsina.
• Impinduka mu muvuduko w'amaraso zishobora gutera ibintu nko kuzungera cyangwa gucika intege .
• Kubyimba umunwa, umuhogo, cyangwa inzira z'ubuhumekero bishobora gutuma bigorana guhumeka no kuvuga. Iki ni cyo kintu giteje akaga cyane. Iyo habaye ikintu nk'iki, ni ikibazo cyihutirwa cy'ubuvuzi. Ugomba kujya kwa muganga ako kanya!

Icy'ingenzi kurushaho: Niba umuhogo wawe ubyimbye kandi ukumva ufite ikibazo cyo guhumeka, ntabwo ari urwenya. Shaka inama kwa muganga ako kanya.

Kuki habaho edema ya angioedema? Ni izihe mpamvu?

Impamvu zitera angioedema ziratandukanye bitewe n'ubwoko bwa angioedema ufite. Ariko, impamvu ikunze kugaragara ni allergie . Hari ubwoko bwinshi bwa allergie bushobora kuyitera:

• Allergie ku biribwa: Ibi biterwa ahanini n'amata, amagi, imbuto nk'amakashe, n'ibikomoka ku mafi nk'amashellfish.
• Allergie ku miti: Antibiyotike nka penisiline na sulfa, imiti idakoresha steroide igabanya ubushyuhe (NSAIDs), hamwe n'ibindi bikoresho bikoreshwa mu isuzuma rimwe na rimwe bishobora gutera ibi. Ubwo bwoko bw'allergie bushobora gutera indwara zo mu nda.
• Uburozi: Uburozi buturuka ku dukoko, kandi gake cyane buturuka ku nyamaswa nka brown recluse spider.
• Latex isanzwe ya rubber: Latex ni ibikoresho bikoreshwa mu gukora ibintu nk'uturindantoki, udupira tw'amapine, udukingirizo, na catheter zo kwa muganga. Muganga wawe ashobora kuba yakubajije niba ufite ubwivumbure kuri latex.

Izindi mpamvu zirimo ibibazo byo mu muryango ndetse n’ibibazo bya nyuma bya poroteyine ibuza C1, ingaruka z’imiti zibaho zidakurura cyangwa ngo zihinduke (izi si allergie zisanzwe), hamwe n’ingendo zihindagurika.

Ese indwara ya Angioedema yandura?

Oya, ntabwo ari byo na gato.Ntushobora kwandura angioedema iturutse ku wundi muntu, kandi ntushobora kuyikwirakwiza ku wundi muntu. Si indwara yandura.

Ni gute usuzuma indwara ya angioedema? Abaganga bareba iki?

Bishobora kugorana kumenya neza ubwoko bwa angioedema ufite. Muganga wawe abanza kugusuzuma umubiri, ariko akenshi kubyimba bigaragara byoroshye. Hanyuma azakubaza ibibazo bike:

• Kubyimba byatangiye ryari?
• Ese hari ikintu cyose utekereza ko cyaba cyarateye iyi ndwara wariye, wanyoye, wafashe cyangwa wakozeho?
• Ni iyihe miti n'inyongeramusaruro urimo gufata ubu?
• Ese hari ubwo habayeho imyitwarire nk'iyi mbere?
• Hari undi muntu mu muryango wawe warwaye indwara nk'iyi?

Uretse kubaza ibi bibazo, muganga wawe ashobora gutegeka ko hapimwa amaraso cyangwa hapimwa uruhu kugira ngo arebe niba hari ubwivumbure , cyangwa se hapimwa amaraso kugira ngo arebe niba hari angioedema ifitanye isano na poroteyine ibuza C1.

Ni ubuhe buryo bwo kuvura indwara ya Angioedema?

Uburyo bwo kuvura angioedema buratandukanye bitewe n'ubwoko bw'indwara ufite.

• Ku bijyanye n'ingaruka zikomeye z'ubwivumbure , muganga wawe ashobora kuguha urushinge rwa epinephrine ushobora kugumana nawe igihe cyose. Ugomba kwitera uru rushinge igihe uhamagaye 911 (1990 muri Sri Lanka) mu gihe cy'ubutabazi bwihutirwa.
• Ku ndwara ya angioedema ifite ubwivumbure , muganga ashobora kukwandikira imiti igabanya ubukana bw'indwara cyangwa steroid . Iyi miti ishobora gufatwa nk'ibinini, nk'amazi (mu kanwa), cyangwa igatangwa mu mitsi.
• Niba ufite ikibazo cy’imiti kidatera allergie , muganga wawe azagushakira ubundi buryo bukwiye bwo gufata umuti utera kubyimba. Ntugahagarike gufata imiti yawe utabanje kugirwa inama na muganga.

Imiti yo mu rugo irimo gusiga urubura kugira ngo igabanye kubyimba, kwiyuhagira mu mazi akonje, no gushyira igitambaro gikonje kandi gitose ku gace kabyimbye. Ibi bishobora gufasha kubyimba ahantu runaka, kubyimba ku minwa yose, cyangwa ku maso afite ibibyimba.

Niba ufite ikibazo cyo kubura amaraso mu buryo bw’umubiri (angioedema) bitewe n’uko usanzwe ufite, cyangwa ufite ikibazo cyo kubura amaraso mu buryo bw’umubiri (C1 inhibitor deficiency ), ushobora koherezwa kwa muganga w’inzobere. Imwe mu miti ikoreshwa mu kuvura cyangwa gukumira indwara yo kubura amaraso mu buryo bw’umubiri (HAE) irimo:

• Umuti ugabanya ubukana bwa C1 esterase (recombinant) (Ruconest®)
• Umuti ubuza C1 (umuntu) (Berinert®, Cinryze®, Haegarda®)
• Ecallantide (Kalbitor®)
• Icatibant (Firazyr®)
• Lanadelumab (Takhzyro®)
• Berotralstat (Orladeyo®)

Ese hari uburyo bwo kwirinda indwara ya angioedema?

Yego, hari uburyo bumwe na bumwe.

• Niba ufite indwara ya angioedema iterwa n'ubwivumbure , ushobora kuyirinda wirinda ibiryo, imiti, cyangwa ibindi bintu (bitera) gutera ubwivumbure.
• Niba urwaye indwara ya angioedema idafite allergie mu gihe ufata imiti ya ACEI (ACE inhibitors) , ugomba kuvugana na muganga wawe ku bijyanye no guhindura undi muti.

Ni iki umuntu urwaye angioedema ashobora kwitega?

Indwara nyinshi za angioedema ntizimara igihe kirekire . Akenshi zikemuka ubwazo. Ariko, mu bihe bikomeye, ubuvuzi burakenewe kugira ngo inzira z'ubuhumekero zigume zifunguye.

Ese indwara ya angioedema ishobora kwica? Ese ibi biteje akaga?

Ku bantu bamwe, indwara ya angioedema ishobora gutera indwara yitwa anaphylaxis - kubyimba gukabije kw'inzira z'ubuhumekero n'ibihaha. Ibi bishobora gushyira ubuzima mu kaga . Abaganga bagira inama abantu bafite iyi ndwara yo gutwara imiti iterwa na epinephrine (EpiPen®, Auvi-Q®, Adrenaclick® n'izindi) kugira ngo bavure ingaruka zikomeye z'uburwayi.

Impamvu iyo ari yo yose, indwara ya angioedema ifata inzira z'ubuhumekero ihora ari ikibazo cyihutirwa. Kubwibyo, hakenewe ubuvuzi bwihuse. Hari igihe igikorwa cyo kubaga cyitwa tracheostomy (gukora umwobo mu muyoboro w'amazi) gishobora kuba ngombwa kugira ngo gifashe mu guhumeka.

Niba mfite angioedema, nakwiyitaho nte?

Niba ufite indwara ya angioedema, ugomba kwirinda ibintu bitera allergie . Niba muganga wawe akwandikiye imiti yo gukumira ibindi bihe, fata neza nk'uko byategetswe. Niba wabwiwe gutwara umuti wa epinephrine uterwa inshinge , menya neza ko uhora uwufite. Igisha umuryango wawe n'inshuti zawe uburyo bwo kuwukoresha.

Ni ryari ngomba kujya kwa muganga?

Niba ufite ubwivumbure bukomeye kandi kubyimba bikagira ingaruka ku nzira z'ubuhumekero, hamagara 1990 (ambulance yihutirwa) ako kanya.

Mu bihe bidakabije cyane, niba ukomeje kugira angioedema, reba muganga wawe. Bashobora kuganira ku buryo bwo kwirinda. Ubundi buryo bwo kuvura burimo imiti igabanya ubukana bw'imiti ikoreshwa mu kunywa na steroid. Idiopathic, bigoye kuvura.Abaganga bamwe bakoresheje antibody ya monoclonal yitwa Omalizumab (Xolair®) kuri angioedema (idiopathic angioedema).

Amaherezo, ibintu by'ingenzi cyane ugomba kwibuka

Niba amaso yawe, iminwa yawe, cyangwa amaboko yawe yumva yabyimbye, bishobora kuba ari ikibazo cy'uruhu cyitwa angioedema. Ibi birashoboka cyane niba urwaye allergie. Andika igihe n'igihe ibi bibaho, kandi wige kwirinda ibintu ufite allergie. Niba uzi ko hari abandi bantu bo mu muryango wawe bahuye n'ibi bibazo, bwira muganga wawe. Ashobora kukugira inama yo gupima niba iki kibazo kiri mu muryango wawe. Niba ufite angioedema iterwa na allergie, ni ngombwa cyane kubika epinephrine hafi yawe, kuko kubyimba mu myanya y'ubuhumekero bishobora gutuma uhagarika guhumeka. Ntugatinye, ariko ni byiza kubimenya no gufata ingamba zikenewe.

Edema ya angioedema, kubyimba, ubwivumbure, indwara z'uruhu, ubuvuzi bwihutirwa, epinephrine, urticaria