Ese ufite ikibazo cyo kuba ufite calcium nkeya nyuma yo kubagwa? Bishobora kuba ari 'Hungry Bone Syndrome'!

Nkuko mubizi, nyuma yo kubagwa bimwe na bimwe, cyane cyane ibyo gukuraho ingirabuzimafatizo ya tiroyide mu ijosi cyangwa ingirabuzimafatizo za parathyroid ziri hafi aho, umubiri ushobora kugira ubwoko butandukanye bw'ububabare. Hari abantu bashobora kumva bananiwe cyane, bababara umubiri, cyangwa bakumva batazi neza. Niba rero wowe cyangwa undi muntu uzi arimo guhura n'ikintu nk'iki, bishobora kuba biterwa n'indwara tugiye kuvugaho uyu munsi yitwa 'Hungry Bone Syndrome'. Izina risa n'aho ritangaje gato, si byo se? Ushobora kuba utekereza uti "Kugira amagufwa ashonje bivuze iki?" Reka turebere hamwe icyo ari cyo, mu magambo make.

'Hungry Bone Syndrome' ni iki?

Muri make, Hungry Bone Syndrome ni indwara aho urugero rwa kalisiyumu mu maraso yawe rugabanuka cyane. Abaganga bayita "Hypocalcemia". Iyi ndwara ikunze kugaragara nyuma yo kubagwa ku ngirabuzimafatizo za parathyroid. Ese wari uzi ko ngirabuzimafatizo za parathyroid ari ingenzi cyane mu kugenzura kalisiyumu mu mubiri wacu?

Abantu bafite iyi 'syndrome y'amagufwa ashonje' bashobora kuba badafite calcium nkeya gusa, ahubwo rimwe na rimwe bashobora no kuba bafite magnesium nkeya (`(Hypomagnesemia)`) na fosifore (`(Hypophosphatemia)`) mu maraso yabo. Izi nazo ni imyunyu ngugu y'ingenzi umubiri wacu ukeneye.

Ariko nta kibazo kirimo. 'Hungry Bone Syndrome' ni indwara ishobora kuvurwa igakira . Ikintu cy'ingenzi ni ukubimenya ku gihe no gutangira kuvurwa.

Iyi ndwara ikunze kugaragara gute?

Abashakashatsi ntibafite igitekerezo nyacyo cy’uburyo iyi 'syndrome y’amagufwa ashonje' ikunze kugaragara, kuko ishobora gutandukana bitewe n’umuntu ku wundi.

Ariko, ubushakashatsi bumwe bwagaragaje ko abantu bari hagati ya 4 na 13 mu 100 bakorewe parathyroide de caution kubera indwara yitwa primary hyperparathyroidism barwara iyi ndwara. Nanone, raporo zimwe na zimwe zivuga ko nyuma yo kubagwa hyperparathyroide de caution ya kabiri n'iya gatatu, amahirwe yo kurwara iyi ndwara ashobora kuba hagati ya 20 na 70 mu 100. Rero, bigaragara ko ibi bishobora kugaragara cyane mu bihe bimwe na bimwe.

Ni ibihe bimenyetso bya 'Hungry Bone Syndrome'?

Ibimenyetso bya 'Hungry Bone Syndrome' bisa cyane n'ibiterwa no kugabanuka kwa kalisiyumu mu maraso (Hypocalcemia). Ibi bishobora kuba bito nk'agahu gato ku bantu bamwe, ndetse bikaba bikomeye nko mu rujijo cyangwa gucika intege mu bandi. Dore bimwe mu bimenyetso:

• Kuzunguruka cyangwa gukurura inyama: Kumva nk'aho inyama zo mu maguru cyangwa mu maboko zizunguruka gusa.
• Intege nke z'imitsi: Kumva nta buzima ufite kandi unaniwe cyane ku buryo utabasha gukora ikintu icyo ari cyo cyose.
• Kubabara amagufwa: Kumva nk'aho amagufwa yo mu mubiri arimo kubabara.
• Umunaniro mwinshi: Umunaniro udashira nubwo wamaze gusinzira.
• Urujijo: Kugorwa no kwita ku bintu, kutamenya icyo gukora.
• Ibibazo byo kwibuka: Kwibagirwa ibintu.
• Kurakara cyangwa kurakara: Kurakara kubera utuntu duto, kumva ubabaye.
• Kwiheba: Kumva ufite agahinda no kwiheba.
• Kubura ibinya mu minwa, ku rurimi, ku ntoki, no/cyangwa ku birenge: Utu duce twumva tudafite ibinya, cyangwa nk'aho imboro ziruka hirya no hino.
• Guhumeka bigoranye bitewe no kubabara kw'imitsi yo mu muhogo (`(Laryngospasm)`): Ibi ni akaga gato, bituma guhumeka bigorana.
• Kugorama kw'imitsi no kunyaragura (`(Tetany)`): Indwara ituma imitsi y'umubiri ikomera kandi ikanyagira.
• Indwara zo mu mutwe: Iki nacyo ni ikimenyetso gikomeye.

Hamwe n'ibi bimenyetso, nk'uko byavuzwe mbere, urugero ruto rwa manyeziyumu na fosifore mu maraso (`(Hypomagnesemia)` na `(Hypophosphatemia)`) rushobora no kubaho. Ibimenyetso by'ibi bibazo bisa cyane n'iby'uko kalisiyumu nkeya. Bishobora kandi gutera ibibazo by'imitsi, ibicurane, no gutera umutima mu buryo butari bwo (`(Arrhythmia)`).

Indwara y'amagufwa ashonje ikunze kubaho mu masaha 18 nyuma yo kubagwa parathyroid cyangwa tiroyide .

Kuki iyi 'Syndrome y'amagufwa ashonje' ibaho?

Hari impamvu nyinshi z'ingenzi zitera 'Hungry Bone Syndrome':

• Nyuma yo kubagwa parathyroid (`(Parathyroidectomy)`) kubera hyperparathyroidism y'ibanze cyangwa iya kabiri.
• Thyrotoxicosis ni indwara ibaho nyuma yo kubagwa burundu kwa tiroyide.
• Iyo kanseri ya prostate ikwirakwira mu magufwa (ifite metastasized).

Kugira ngo dusobanukirwe neza impamvu ibi bibaho, ni ngombwa gusobanukirwa gato uburyo urugero rwa kalisiyumu rugenzurwa mu mibiri yacu.

Tekereza, inyuma y’agahu ka tiroyide mu ijosi ryawe, hari utunyangingo tune duto twitwa parathyroid glands. Utu tunyangingo dukora imisemburo yitwa parathyroid hormone (PTH) . Akamaro k’ingenzi k’iyi hormone ya PTH ni ukugenzura urugero rwa kalisiyumu mu maraso (atari mu magufwa, ahubwo mu maraso). PTH ifasha kandi kugenzura urugero rwa fosifore (nayo ni imyunyungugu) na vitamine D (nayo ni imisemburo) mu maraso no mu magufwa.

Rero, iyo umubiri wawe umenye ko urugero rwa kalisiyumu mu maraso yawe ruri hasi, uturemangingo twa parathyroid dusohora imisemburo ya PTH. Iyi PTH iragenda ikavanamo kalisiyumu nke mu magufwa ikayishyira mu maraso. Hanyuma urugero rwa kalisiyumu mu maraso rusubira ku buryo busanzwe.

Noneho, tekereza ko hari umuntu ufite imisemburo ya parathyroid ikora cyane, maze akabagwa kugira ngo ayikureho. Icyaba gihari ni uko urugero rw'imisemburo ya PTH yari iri hejuru cyane rugabanuka mu buryo butunguranye. Hari igihe, iyo habayeho kubagwa kwa tiroyide, iyo imisemburo ya parathyroid iri hafi aho yangiritse ku buryo butunguranye, urugero rwa PTH narwo rushobora kugabanuka.

Iyo urugero rwa PTH rugabanutse mu buryo butunguranye, ingano ya kalisiyumu mu magufwa ashaje ishyirwa mu maraso (`(Resorption)`) iragabanuka, kandi ingano y'imiterere mishya y'amagufwa (`(Guhinduka kw'amagufwa)`) iriyongera. Ibi bituma amagufwa "yicwa n'inzara" ya kalisiyumu. Niyo mpamvu ibi byitwa 'hungry bone syndrome'.

Ibi nibyo bibaho iyo kanseri ya prostate ikwirakwira mu magufwa. Aho niho imikorere y'uturemangingo yubaka amagufwa (`(ibikorwa bya osteoblastic)`) irazamuka, bityo amagufwa agakenera kalisiyumu nyinshi.

Ni nde ufite ibyago byinshi byo kurwara indwara ya 'Hungry Bone Syndrome'?

Hari abantu bashobora kurwara iyi ndwara cyane. Reka turebe abo ari bo:

• Imisemburo ya parathyroid (PTH) iri hejuru cyane mu maraso.
• Ubwiyongere bwa alkaline fosfati mu maraso.
• Urugero rwa kalisiyumu mu maraso akenshi ruba ruri hasi.
• Kugira ikibazo cyo kubura Vitamine D.
• Gukora ubuvuzi bwa tiroyide na parathyroid icyarimwe.
• Ubwiyongere bw'urugero rwa azote ya urea mu maraso (BUN).
• Umubyibuho ukabije, ni ukuvuga umubyibuho ukabije.
• Gukuraho akabaga agakoko ka parathyroid kanini kurusha akasanzwe.
• Gukwirakwira kw'uturemangingo twa kanseri mu magufwa (Metastatic tumors of the flesh).
• Kugaragara kw'indwara ziterwa n'amagufwa nka kanseri y'umukara na osteitis fibrosa cystica.

Abantu bafite ibi bintu bishobora gutera indwara y’amagufwa bakunze kurwara indwara ya “hungry bone syndrome”.

Abaganga babibona bate?

Akenshi umuganga abanza kumenya niba ufite 'hungry bone syndrome' akoze ikizamini cy'amaraso cya calcium. Muri rusange, niba urugero rwa calcium mu maraso yawe ruri munsi ya 8.4 mg/dL mu gihe kirenze iminsi ine, bifatwa nk'ikintu gishobora gutera 'hungry bone syndrome'.

Si ibyo gusa, kandi muganga wawe ashobora no gukora ibindi bipimo bike kugira ngo arebe niba iyi ndwara yagize ingaruka ku bindi bice by'ubuzima bwawe:

• Ibindi bipimo by'amaraso: Mu maraso yawe hashobora gupimwa magnesium, fosifore, parathyroid hormone (PTH), na/cyangwa vitamin D.
• EKG (Electrocardiogram): Iki kizamini gipima umuvuduko w'umutima wawe gikoresheje electrodes mu gituza cyawe. Ibi ni ingenzi kuko kalisiyumu nke mu maraso (hypocalcemia) na 'hungry bone syndrome' bishobora gutera umutima utera nabi.
• Ibipimo byo gupima amagufwa: Ibi bizamini bishobora gusuzuma ibibazo biri mu magufwa yawe, nko kuvunika, ubumuga, cyangwa ibibyimba.

Ni ubuhe buryo bwo kuvura indwara ya 'Hungry Bone Syndrome'?

Ntugahangayike, hari uburyo bwiza bwo kuvura ibi. Intego nyamukuru yo kuvura ni ukugarura urugero rwa kalisiyumu mu maraso yawe ku rugero rwiza. Kenshi na kenshi, uzahabwa ubu buvuzi uri mu bitaro. Ubuvuzi bushobora kuba burimo:

• Gutanga kalisiyumu binyuze mu mitsi (`(IV Calcium - Calcium Gluconate)`): Ibi bifasha gusubiza vuba urugero rwa kalisiyumu.
• Inyongeramusaruro za Kalisiyumu mu kanwa (Calcium Citrate cyangwa Calcium Carbonate): Izi zitangwa kugira ngo hagumane urugero rwa kalisiyumu.
• Inyongera za Vitamine D zo mu kanwa: Vitamine D ni ingenzi kugira ngo umubiri ushobore kwinjiza kalisiyumu.
• Gusimbuza manyeziyumu: Niba urugero rwa manyeziyumu ruri hasi, nabyo bigomba gukosorwa.

Abaganga bazasuzuma indwara yawe maze baguhe uburyo bwiza bwo kuvura.

Bizatwara igihe kingana iki kugira ngo umuntu akire iyi ndwara? Ejo hazaza ni he?

Inkuru nziza ni uko iyi ndwara, 'Hungry Bone Syndrome', hafi ya yose ishobora gukira . Ibyo bivuze ko iteganyagihe ari ryiza cyane.

Ariko, nubwo haba hari uburyo bwo kuvurwa, igihe bifata kugira ngo iyi ndwara ikemuke burundu gishobora gutandukana. Hari abantu bakira mu minsi mike, abandi bagafata amezi menshi. Mu bihe bike cyane, ishobora kumara umwaka wose.

Ikirenze ibyo, iyo idavuwe, kubura kwa kalisiyumu mu mubiri bishobora gutera ingorane zishobora guterwa n’ubuzima nko gukubita ibisebe. Kubwibyo, ni ngombwa gushaka ubuvuzi vuba bishoboka mu gihe ibimenyetso bigaragaye.

Ese indwara ya 'Hungry Bone Syndrome' ishobora kwirindwa?

Kubera ko 'hungry bone syndrome' ishobora kubaho nyuma yo kubagwa parathyroid (`(Parathyroidectomy)`) cyangwa kubagwa tiroyide (`(Thyroidectomy)`), abaganga bagerageza gufata ingamba zo kuyikumira mbere yuko ibagwa. Reka turebe ibyo ari byo:

• Isuzuma mbere yo kubagwa: Mbere yo kubagwa , muganga wawe azasuzuma ubucucike bw'imyunyu ngugu mu magufwa yawe, urugero rwa kalisiyumu mu maraso, urugero rwa fosifate, urugero rwa PTH, n'urugero rwa vitamine D. Ibi bizamini bishobora gufasha muganga wawe kumenya niba uri mu kaga ko kurwara 'hungry bone syndrome'.
• Ingamba zo kwirinda:Niba ufite ibyago byinshi byo kurwara 'hungry bone syndrome', muganga wawe ashobora kukugira inama yo gufata imiti cyangwa inyunganiramirire kugira ngo ukomeze kugira vitamine D na kalisiyumu mbere yo kubagwa. Ibi bishobora kugufasha kugabanya ibyago byo kurwara 'hungry bone syndrome'.
• Gukurikirana nyuma yo kubagwa: Nyuma yo kubagwa, itsinda ry’ibitaro rizagenzura buri gihe urugero rwa kalisiyumu, fosifate, manyeziyumu, na PTH mu maraso yawe. Ibi ni ukugira ngo niba urwaye 'hungry bone syndrome', ibashe kumenyekana hakiri kare kandi ubuvuzi bushobore gutangira ako kanya.

Nubwo hari ubwo bipimo byose, hari igihe indwara y’amagufwa iterwa n’inzara ishobora kugaragara. Abashakashatsi ntibaramenya impamvu ibi bibaho.

Ni ryari ngomba kubonana na muganga?

Niba warabazwe parathyroid cyangwa tiroyide hanyuma ukagaragaza ibimenyetso bya calcium nke mu maraso (`(Hypocalcemia)`) twavuze mbere, nko kuribwa mu mitsi, kumva ufite intege nke, impinduka mu bwenge (nk'urujijo), no kubura iminwa n'intoki, ugomba kujya kwa muganga vuba bishoboka.** 'Hungry bone syndrome' na '(Hypocalcemia)` bishobora kubaho nyuma yo kubagwa parathyroid cyangwa tiroyide, bishobora kugabanuka nyuma y'iminsi mike, hanyuma bikagaruka. Kubwibyo, ni ngombwa cyane kwitondera n'ikimenyetso gito cyane.

'Hungry bone syndrome' ni indwara ishobora kubaho nyuma yo kubagwa kugira ngo hakurweho parathyroid cyangwa thyroid glands. Inkuru nziza ni uko ishobora kuvurwa igakira. Ariko, bishobora gufata igihe kugira ngo ikire neza. Kubera ko kugabanuka gukabije kwa calcium mu maraso bishobora guteza akaga ku buzima bwawe, ni byiza kujya kwa muganga ukimara kubona ibimenyetso.

Jyana ubutumwa mu rugo

Mu magambo make rero, 'Hungry Bone Syndrome' ni indwara ishobora kubaho nyuma yo kubagwa kuri parathyroid cyangwa thyroid gland. Icyo ikora cyane ni uko ingano ya kalisiyumu mu maraso y'umubiri igabanuka mu buryo butunguranye. Ibi biterwa nuko urugero rw'imisemburo ya parathyroid (`(PTH)`) igabanuka nyuma yo kubagwa, bigatuma amagufwa "asaba" kalisiyumu.

Ntugatinye kumva ibi, kuko 'Hungry Bone Syndrome' ni indwara ishobora kuvurwa igakira neza.

Igikuru ni uko niba ufite kimwe muri ibi bimenyetso (nk'imitsi ihinda umushyitsi, umunaniro, ibinya), ntugapfushe umwanya ngo ugende kwa muganga vuba bishoboka. Muri ubu buryo, ushobora kumenya indwara hakiri kare, ugatangira kuvurwa vuba, hanyuma ukayikira mbere yuko ihinduka ikibazo gikomeye. Wibuke ko kwita ku buzima bwawe biri mu maboko yawe.

"Indwara y'amagufwa ashonje, Indwara y'amagufwa ashonje, Kalisiyumu, Hypocalcemia, Parathyroid, Kubagwa kwa Thyroid, PTH