Unonzwawo here kuvaviwa, mapundu, uye maziso matsvuku, ane mvura kana ukabata guruva, kubuda kunze kuchitonhora, kana kudya chimwe chinhu? Dzimwe nguva unonetseka here kufema? Tinowanzoti izvi 'allergy'. Saka nhasi tichataura nezvemumwe wevanhu vakuru vari shure kweallergy iyi. Iye ihistamine. Ungave wakanzwa zita iri kubva kuna chiremba kana kubva kuzita remushonga waunotora weallergies yako. Ngationei kuti histamine chii uye kuti inoitei mumuviri.
Zvichitaurwa zviri nyore, ndiani uyu histamine?
Funga nezvemuviri wedu senyika yakachengetedzwa zvakanaka. Kunyangwe kana murwi wekunze akapinda munyika ino, kunyangwe chinhu chisina njodzi kumuviri wedu (semuenzaniso, kaguruva, ruva, kana chikafu chakaita sekadova), dziviriro yedu (immune system) dzimwe nguva inofungidzira kuti muvengi.
Panguva iyoyo, masero ari muimmune system yedu anoburitsa kemikari kuti ataure nemamwe masero, kuti ataurirane mameseji. Zvakafanana neshoko renyevero rinoti, "Heuno muvengi ari kuuya, ita nekukurumidza!" Nhume iyoyo inonzi histamine.
Kemikari iyi inonzi histamine inochengetwa mumiviri yedu kunyanya mumhando mbiri dzemasero.
1. Masero emudumbu: Aya rudzi rwemasero machena eropa anowanikwa mumiviri yedu yese. Anowanikwa zvakanyanya pasi peganda, pedyo netsinga dzeropa nemidziyo yelymph, mutsinga, mapapu, nemudumbu.
2. Basophils: Iyi imwe mhando yemasero machena eropa anowanikwa muropa.
Kana chimwe chinhu chinokuvadza chikasangana nemuviri, masero aya anoburitsa histamine, zvichikonzera zviratidzo zvekurwara. Kazhinji, zviratidzo izvi zvinongogumira panzvimbo imwe chete yemuviri, asi dzimwe nguva izvi zvinogona kuva zvakanyanya . Tinozvidaidza kuti anaphylaxis . Iyi idambudziko rinokanganisa muviri wese uye rinogona kutoisa hupenyu panjodzi.
Chii chinoita kuti histamine ishande mumuviri? Chii ichi nezvemareceptors?
Histamine haisi munhu akaipa chete anokonzera allergies. Inoita mabasa akawanda akakosha mumuviri. Zvinoitwa nehistamine mumuviri zvinoenderana nereceptor yainosunga pairi. Sezvo kiyi imwe chete ichigona kuvhura magonhi akati wandei, imba yaunopinda ichasiyana zvichienderana negonhi raunovhura. Masayendisiti akaona mhando ina dzehistamine receptors.
Ngatitarisei izvi kuti tizvinzwisise zvakajeka.
| Rudzi rweReceptor | Nzvimbo huru | Chii chinoitika kana ikashandiswa? |
|---|---|---|
| H1 inogamuchira | Mumuviri wese, kunyanya mumasero etsinga, nzira dzekufema, uye masero emhasuru dzakatsetseka mutsinga dzeropa. |
|
| H2 inogamuchira | Zvikurukuru mumasero anogadzira acid mudumbu, masero emhasuru dzakatsetseka, uye masero emwoyo. | |
| H3 receiver | Mumasero etsinga dzetsinga dzepakati petsinga (uropi). | |
| H4 receiver | Mumabhonzo nemasero asina kukura anova masero eropa. |
Unonzwisisa here? Izvi zvinoreva kuti kunyangwe tichifunga kuti iallergy, histamine inobatanidzwa muzvinhu zvakawanda mumuviri wedu, zvakaita sekurara, kurangarira, kudzidza, uye kudzora tembiricha yemuviri.
Ndezvipi zvirwere zvikuru zvinogona kusanganiswa ne histamine?
Zvirwere zvekurwara nepfungwa zvinonyanya kukonzerwa nekushanda kwemushonga we "messenger histamine". Heano mimwe mienzaniso:
- Atopic dermatitis (inozivikanwawo se eczema): Chirwere chinoita kuti ganda riome, ritsvuke, rive neganda rine mavanga, uye rikwenye zvakanyanya, zvinowanzonzi 'eczema'.
- Kusangana neganda: Kurwara kunoitika kana chimwe chinhu chikasangana neganda. Semuenzaniso, kunhuhwirira kwakagadzirwa, simbi dzakati wandei (senge nickel), uye zvinochengetedza.
- Allergic rhinitis (inozivikanwawo sehay fever): Ichi chirwere chinowanzoitika kuvanhu vazhinji. Chinokonzerwa nezvinhu zvakaita seguruva, mukume, dander yemhuka dzinovaraidza, uye guruva, zvichikonzera mhino inoyerera, mhino inoyerera, uye mhino dzakavharika.
- Asima yeAllergy: Zvikonzero zvakafanana nezvataurwa pamusoro apa, asi pano nzira dzekufema dzinova dzakatetepa, zvichikonzera kutadza kufema nekufemera.
- Kurwara kwemaziso: Chirwere chekuti conjunctiva yemaziso inozvimba, inotsvuka, inokwenya, uye inonyorova nekuda kwechinhu chinokanganisa maziso.
Chii chinonzi Histamine Intolerance?
Izvi zvakasiyana zvishoma. Dzimwe nguva huwandu hwe histamine mumuviri wedu hunokwira zvakanyanya. Izvi zvinokonzerwa nekuti muviri haugone kuputsa histamine zvakanaka. Kana izvi zvikaitika, zviratidzo zvakasiyana-siyana zvinogona kuitika.
- Musoro kana migraine
- Kuzara kwemhino
- Kugara wakaneta
- Makonzo
- Matambudziko ekugaya chikafu
- Kuenda kumwedzi kusingaenderani nevakadzi
Kana uine zviratidzo izvi nguva dzose, zvakakosha kuti uone chiremba wotaura nezvazvo.
Saka unodzora sei histamine iyi?
Kune nzira dzakasiyana-siyana dzinokurudzirwa navanachiremba kudzora kusagadzikana kunokonzerwa nehistamine. Idzi ndidzo dzinouya mupfungwa dzako paunonzwa izwi rekuti mushonga weallergy.
- Mishonga yeH1 antihistamines: Iyi ndiyo mishonga yatinowanzo ziva se'allergy pills'. Inoshanda nekuvharira maH1 receptors ataurwa pamusoro apa. Izvi zvinodzivirira histamine kuti isasungane nemareceptor iwayo zvichikonzera kuvaviwa uye mapundu. Izvi zvinouya nenzira dzakasiyana-siyana, dzinosanganisira mapiritsi, manyuchi, mafuta ekuzora, uye madonhwe emaziso. Mimwe yacho inogona kutorwa pasina kunyorerwa nachiremba, asi zvakanaka kubvunza chiremba wako kuti ndeipi mishonga yakakunakira.
- Mishonga yeH2 antihistamines: Iyi inonyanya kushandiswa pakurapa matambudziko emudumbu. Inopihwa kune zvirwere zvakaita segastritis, gastroesophageal reflux disease (GERD), uye indigestion (dyspepsia). Inoshanda nekuvharira maH2 receptors mudumbu anogadzira acid.
- Corticosteroids: Tinodaidza kuti 'steroids'. Dzinobatsira kuderedza kuzvimba kunokonzerwa nehistamine. Semuenzaniso, mishonga yakawanda yekufema inoshandiswa kudzora asthma ine mishonga iyi yesteroid.
- Jekiseni reEpinephrine: Izvi zvakakosha zvikuru. Jekiseni iri rinopihwa senzira yekurapa nekukurumidza mumamiriro ezvinhu ane njodzi yehupenyu, akadai seallergy yakanyanya, kana anaphylaxis. Rinokurumidza kuvhura nzira dzekufema uye rinodzorera BP.
- Dzimwe ongororo dzakawana kuti mamwe mavhitamini, akadai sevhitamini C, mhangura, uye vhitamini B6, anogona kubatsira kuderedza huwandu hwehistamine mumuviri. Zvisinei, usatore chero chimwe chezvinowedzera izvi usati watanga wataura nachiremba wako.
Ndinofanira kuona chiremba rini?
Kana uine allergies dzemwaka kana kuti uri kuona zviratidzo zvekusawirirana nechimwe chinhu, kunyanya kana zvichikanganisa mabasa ako ezuva nezuva, zvakakosha kuona chiremba. Chiremba wako anogona kuita bvunzo kuti aone kuti chii chaizvo chauri allergies uye kukurudzira kurapwa kwakanakira iwe. Zvakare, taura nachiremba wako nezve chero zviratidzo zvekusawirirana nehistamine zvataurwa pamusoro apa.
Kunyange hazvo histamine ichikosha pakushanda zvakanaka kwemuviri wedu, dzimwe nguva kana yanyanya kushanda, inogona kutikonzera matambudziko akawanda. Saka, hapana chikonzero chekutambura nekusagadzikana kwakadaro. Matambudziko aya anogona kudzorwa zviri nani nekutsvaga mazano akakodzera echiremba.
Mharidzo Yekuenda Nayo Kumba
- Histamine ikemikari inoburitswa nemasoja edu ekudzivirira muviri.
- Histamine ndiyo inonyanya kukonzera zviratidzo zvakawanda zvekurwara, zvakaita sekurumwa, kuhotsira, uye kuvharika kwemhino.
- Histamine inosunga kune ma receptors anonzi H1, H2, H3, uye H4 ari munzvimbo dzakasiyana dzemuviri uye inoita mabasa akasiyana-siyana.
- Mishonga yakaita seantihistamines inogona kudzivirira kushanda kwehistamine uye kudzora zviratidzo zvekurwara.
- Kana zviratidzo zvako zvekurwara nepfungwa zvakanyanya kana kuti zvichikanganisa hupenyu hwako hwezuva nezuva, iva nechokwadi chekuona chiremba kuti akupe mazano akakodzera uye kurapwa.
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