Chii chinonzi AA Amyloidosis? Ngatidzidzei nezvazvo zviri nyore!

Wakambozvibvunza here kuti chii chingaitika kana mamwe mapuroteni mumiviri yedu akakanganisika? Nhasi tichataura nezvechimwe chirwere chisingawanzoitiki, asi chakakosha chekuziva. Chinonzi AA Amyloidosis.

Chii chinonzi AA Amyloidosis? Ngatinzwisise zviri nyore!

Zvichitaurwa zviri nyore, AA Amyloidosis ndeimwe yemhando huru yezvirwere zvinonzi amyloidosis. Zvino ungave uchibvunza kuti, 'Chii chinonzi amyloidosis iyi?' Miviri yedu ine mhando yeprotein inonzi amyloid. Mapuroteni aya ane chimiro chetatu-dimensional (3D structure). Ndiwo mashandiro aanoita. Zvisinei, dzimwe nguva mapuroteni aya anochinja chimiro chawo, anobatana sebhora reshinda, uye anoumba shinda diki (fibrils). Izvi ndizvo zvatinodaidza kuti 'amyloid deposits'. Kuunganidzwa kwezvicherwa izvi munhengo dzedu dzakasiyana-siyana nematishu kunonzi amyloidosis.

Muchirwere cheAA amyloidosis, huwandu hweprotein A muropa hunowedzera zvakanyanya nekuda kwekuzvimba kwakanyanya mumuviri wedu. Kana uine hutachiona kwenguva refu kana chirwere chekuzvimba, huwandu hweprotein A muropa hunogona kuwedzera. Neimwe nzira, AA amyloidosis idambudziko guru rezvirwere izvi zvekuzvimba. Vanachiremba vanorapa nekurapa chirwere chekuzvimba chiripo.

AA amyloidosis inokanganisa sei muviri wedu?

Iye zvino ngationei kuti chirwere ichi cheAA amyloidosis chinokanganisa sei miviri yedu. Chinogona kukuvadza itsvo dzedu zvakanyanya . Kwete izvozvo chete, asi chinogonawo kukuvadza chiropa, spleen, dumbu, uye ura. Kashoma kukanganisa mwoyo. Chimwe chinhu ndechekuti chirwere ichi chinogona kukanganisa huwandu hweprotein muweti yako uye huwandu hwecholesterol muropa rako.

Ichi chirwere chinouraya here?

Ehe, iri idambudziko rakakura chaizvo. Kana AA Amyloidosis ikasarapwa zvakanaka, inogona kuuraya . Yeukai, ndakati izvi zvinokonzerwa nechirwere chinokonzera kuzvimba kwenguva refu. Saka, kana vanachiremba vachirapa chirwere chiripo, vanorapawo AA amyloidosis. Saka hapana chekunetseka nacho, asi chinonyanya kukosha ndechekuzviziva nekukurumidza uye kuwana kurapwa .

Ndiani anonyanya kubatwa neAA amyloidosis?

Kana uchifunga nezvekuti ndiani anogona kubatwa nechirwere ichi, chero munhu ane chirwere chisingaperi chekuzvimba ari panjodzi yekubatwa nechirwere cheAA amyloidosis . Izvi zvinoreva kuti, kana uine chirwere chakadaro, zvakanaka kuzivawo nezvazvo.

Chii chinokonzera AA amyloidosis?

Ngatinyatsoongororai chinokonzera izvi. AA amyloidosis rudzi rweamyloidosis. Vanachiremba vanoti amyloidosis iyi "chirwere chekusawirirana kwemapuroteni." Fungai nezvazvo, mapuroteni edu mamorekuru marefu ane maumbirwo akasiyana-siyana (3D). Mapuroteni aya anoita basa rakawanda mumiviri yedu - kubva pakupa simba, kusvika pakuyera mvura, kusvika pakubatsira kudzivirira zvirwere, kusvika pakupa chimiro chemuviri, kusvika pakufambisa zvinhu, kusvika pakudzora mashandiro emuviri, nezvimwewo.

Kazhinji, mapuroteni aya anobviswa muropa kana basa rawo rapera. Zvisinei, kana paine matambudziko apo mapuroteni aya anopetana zvisina kunaka, mapuroteni anochinja chimiro oita maumbirwo asina kujairika ayo muviri usingakwanise kushandisa kana kubvisa. MuAA amyloidosis, mapuroteni aya asina kujairika anoungana pamwe chete oumba 'amyloid deposits', kana kuti 'fibrils', munhengo dzedu.

Ongororo dzichangobva kuitwa dzakaratidza mamiriro akasiyana-siyana anogona kukonzera AA amyloidosis. Izvi zvinosanganisira mamwe marudzi ekenza yeropa, hutachiona hwebhakitiriya hwakadai semaronda asingaperi, zvirwere zverheumatic zvakaita serheumatoid arthritis, kana zvirwere zvemudumbu zvakaita seCrohn's disease kana ulcerative colitis. Dzimwe nguva, zvinogonawo kukonzerwa nemamiriro ezvinhu ekuzvarwa nawo akadai se periodic fever syndromes akadai se familial Mediterranean fever.

Ndezvipi zviratidzo zveAA amyloidosis?

Zvakanaka, ngationei zviratidzo zveAA amyloidosis. Kazhinji, inokanganisa itsvo. Inogonawo kukanganisa nhengo dzakadai sechiropa, chirebvu, nedumbu. Ona kana uine chimwe chezviratidzo izvi:

• Kuzvimba mumakumbo kana muzvitsitsinho . Izvi zvinogona kuva chiratidzo chedambudziko reitsvo. Zvinogonawo kuva chiratidzo chechirwere cheitsvo chisingaperi.
• Weti ine furo kana furo.
• Weti inobuda shoma pane yakajairika.
• Manyoka asingarapiki.
• Kukura kweitsvo.
• Kukura kwechiropa.
• Kuderera kweropa.
• Kusvotwa nekurutsa.

Vanachiremba vanoongorora sei chirwere cheAA amyloidosis?

Vanachiremba vanoongorora sei chirwere ichi? Vanoita bvunzo dzakawanda. Chinonyanya kukosha i biopsy.

• Kuongororwa kwe "fat pad" : Izvi zvinosanganisira kutora mafuta mashoma kubva pasi peganda redumbu woaongorora. Zviri nyore kwazvo.
• Kuongororwa kwemuviri : Sampuro diki yenyama inotorwa kubva kunhengo inofungidzirwa kuti yakakanganiswa yoongororwa.

Pamusoro pezvo, mimwe miedzo inogona kuitwa kuti ione kana uine imwe mhando yeamyloidosis inonzi ``AL amyloidosis.'' Nekuti zviratidzo zveAL amyloidosis neAA amyloidosis zvakafanana zvikuru, AL amyloidosis imhando yakakomba zvishoma uye inokurumidza kukura .

Ko AA amyloidosis inorapwa sei?

Iye zvino ngationei kuti mishonga yekurapa izvi ndeipi. AA amyloidosis inokonzerwa nechirwere chekuzvimba kwenguva refu chinoita kuti mapuroteni asina kujairika aungane munhengo dzako dzemuviri. Saka, vanachiremba vanorapa nekurapa chirwere chekuzvimba chiripo . Kana ukarapa chirwere chiripo woderedza kuzvimba, chirwere cheAA amyloidosis chinodzorwawo. Sezvo huwandu hwekuzvimba huchidzikira, zviratidzo zvinodzikira zvishoma nezvishoma.

Kunewo mishonga iripo pari zvino yekurapa AA amyloidosis. Vanachiremba nevatsvagiri vari kuramba vachitsvaga nzira itsva dzekurapa. Semuenzaniso, vari kutsvaga nzira dzekubvisa aya maamyloid fibrils muropa asati aungana munhengo dzemuviri, uye vari kuongororawo ma antibodies akagadzirwa murabhoritari anogona kunanga nekubvisa maamyloid fibrils akatoungana munhengo dzemuviri.

Ko AA amyloidosis inogona kudzivirirwa here?

Izvi zvinogona kudzivirirwa here? Kutaura zvazviri, kana uine chirwere chisingaperi chekuzvimba senge rheumatoid arthritis, chinogona kukonzera kuwedzera kwemapuroteni muropa uye kukonzera AA amyloidosis. Saka, nzira chete yekudzivirira izvi ndeyekuwana kurapwa nekukurumidza uye kwakakodzera kwechirwere chisingaperi chekuzvimba chaunacho .

Ko AA amyloidosis inogona kurapwa here?

Ehe, inogona kurapwa. Vanachiremba vanorapa AA amyloidosis nekurapa chirwere chekuzvimba chakakonzera. Kufanana nezvirwere zvakawanda, nzira yakanakisa yekurapa AA amyloidosis ndeyekuongorora chirwere uye kutanga kurapwa nekukurumidza .

Ndinozvitarisira sei?

Kana uine AA amyloidosis, nzira yakanakisisa yekuzvitarisira ndeyekushanda nachiremba wako kuti arape zvakanaka chirwere chekuzvimba chakakonzera. Vatsvagurudzi vakawana zvirwere zvakawanda zvinokonzera kuzvimba kwenguva refu zvakabatana neAA amyloidosis. Bvunza chiremba wako kuti chirwere chako chakakonzera sei AA amyloidosis uye kuti vanorapa sei chirwere ichocho chekuzvimba.

Zvichitaurwa zviri nyore, AA amyloidosis idambudziko risingawanzoitiki, asi rakakomba, rinokonzerwa nezvirwere zvakawanda zvinozivikanwa kana kuti zvirwere zvinozvimba. Nerombo rakanaka, vanachiremba vanogona kurapa chirwere chiripo. Kazhinji, zviratidzo zveAA amyloidosis zvinogona kuita sematambudziko akajairika awakajaira nechirwere chako chinozvimba. Asi, kufanana nezvimwe zvirwere zvakakomba, vanachiremba vanogona kuchirapa kana chikaonekwa nekukurumidza.Kana ukaona shanduko kana zviratidzo zvitsva muarthritis yako, taurira chiremba wako nekukasika . Vachaongorora zviratidzo zvako votsanangura zvazvinoreva.

Saka, ndezvipi zvinhu zvakakosha zvatinofanira kurangarira kubva munyaya iyi?

Izwi rekuti AA Amyloidosis rinotyisa zvishoma, asi zvakakosha kuti urinzwisise nemazvo.

Yeuka, izvi zvinowanzoitika sedambudziko reimwe chirwere chekuzvimba kwenguva refu.

• Kana uine chirwere chisingaperi chekuzvimba, chakadai serheumatoid arthritis, zvakakosha kutsvaga kurapwa kwakakodzera .
• Kana ukava nezviratidzo zvitsva, zvakaita sematambudziko eitsvo (kuzvimba mumakumbo, kuchinja kweweti), manyoka anoramba aripo, kana chiropa kana chiropa chakakura, zivisa chiremba wako .
• Kana AA amyloidosis ikaonekwa ikarapwa nekukurumidza, mhedzisiro yakanaka inogona kuwanikwa . Chinhu chikuru chekurapa kurapa chirwere chekuzvimba chiripo.
• Usatya, asi chenjera . Taura pachena nachiremba wako, muudze matambudziko ako. Vachakubatsira.

Saka, tinovimba kuti ruzivo urwu rwakakubatsira. Ramba uine hutano hwakanaka!

Amyloidosis , AA amyloidosis, mapuroteni, kuzvimba, chirwere cheitsvo, chirwere chisingaperi, rheumatoid arthritis