Wakambonzwa nezvezita rekuti 'Chordoma' here? Pamwe kwete. Nekuti chirwere chisingawanzoitiki, kureva kuti, chirwere chakaipa chisingawanzoonekwi. Bundu iri regomarara rinokura munzvimbo mbiri dzakakosha mumuviri wedu. Imwe musana wedu, uye imwe ndiyo hwaro hwedehenya redu. Zvine musoro kunzwa kutya zvishoma kana izwi rekuti gomarara rataurwa munzvimbo yakadaro. Asi musazvidya mwoyo. Tichataura nezvese nenzira iri nyore, yakajeka, uye inonzwisisika kwauri.
Zvichitaurwa zviri nyore, chii chinonzi Chordoma?
Chordoma igomarara rinokura mumapfupa edu. Kutaura chokwadi, iri muboka regomarara rinonzi sarcomas. Igomarara rinokura zvishoma nezvishoma. Izvi zvinoreva kuti rinogona kuramba risina zviratidzo kwenguva yakareba.
Kenza iyi inogona kuitika chero kupi mumusana, asi pane nzvimbo nhatu dzinonyanya kuwanikwa:
- Nzvimbo yakaderera yemusana (Sacrum): Inenge 35% yema chordomas ese anokura munzvimbo iyi.
- Hwaro hwedehenya: Vamwe vanhu vanosvika 35% vanoonekwa pano. Pfupa panguva iyi rinonzi 'clivus'. Rudzi urwu runonziwo 'clival chordomas'.
- Mamwe ma vertebrae emusana: 30% yasara inowanikwa mune dzimwe nzvimbo dzemusana. Anonyanya kuwanikwa mu cervical vertebra yechipiri, ichiteverwa ne lumbar ne thoracic vertebrae.
Dambudziko guru regomarara iri nderekuti, kunyangwe richikura zvishoma nezvishoma, rinopinda muzvikamu zvakakosha zvetsinga dzakapoteredza. Izvi zvinoreva kuti rinogona kukuvadza nzvimbo dzinonzwa zvakanyanya dzakadai seuropi nemusana.
Chimwe chinhu ndechekuti ine katsika kekudzoka, kunyangwe mushure mekurapwa. Inowanzo dzoka panzvimbo imwe chete yayaive kare. Zvakare, muzviitiko zvinenge 30% - 40%, kenza iyi inogona kupararira (metastasize) kune dzimwe nhengo dzemuviri. Kana ikadaro, inowanzo pararira ku:
- Kumapapu
- Kuma lymph nodes akapoteredza
- Kune mamwe mapfupa
- Kuchiropa
- Kuganda
Kune mhando dzeChordoma here?
Ehe, World Health Organization (WHO) yakaona mhando nhatu huru dzegomarara iri. Kupatsanurwa uku kwakavakirwa pamaitiro anoita masero egomarara pasi pemaikorosikopu (histology). Ngationei kuti ndeapi.
| Rudzi rweChordoma | Tsananguro iri nyore |
|---|---|
| Chordoma Yekare/Yakajairika | Rudzi urwu ndirwo rwakanyanya kuwanda. Runobata 80%-90% yevarwere. Masero aro anoita se "mabhuru" pasi pemaikorosikopu. Chondroid chordoma, inoumbwa pasi pedehenya, imhando yerudzi urwu. |
| Chordoma Yakabviswa Musiyano | Izvi hazviwanzoitiki (zvisingasviki 5%). Zvinoratidzwa nekuunganidzwa kwemasero kusina kujairika. Zvinokura nekukurumidza kupfuura rudzi rwemazuva ese, zvine hukasha, uye zvine njodzi yakakura yekupararira (metastasizing) kune dzimwe nhengo dzemuviri. |
| Chordoma Yakasiyana Zvisina Kunaka | Izvi hazviwanzoitiki. Nyaya dzinosvika makumi matanhatu dzakataurwa muzvinyorwa zvekurapa. Rudzi urwu runoratidzwa nekurasikirwa kwejini rinonzi SMARCB1 kana INI1 mumasero. Rudzi urwu runonyanya kuwanikwa muvana nevechidiki . |
Ndiani ane mukana mukuru wekuwana chirwere ichi? Chinowanikwa kakawanda sei?
Kunyange zvazvo chondroma ichigona kukura chero pazera ripi zvaro, inonyanya kuitika muvanhu vakuru vari pakati pemakore makumi mashanu nemakumi masere. Chikamu chidiki, chinosvika 5%, chinoibata muvana. Uyewo, varume vane mukana wekuwana chirwere ichi kanenge ka1.5 kupfuura vakadzi.
Izvi hazviwanzoitiki zvekuti munhu mumwe chete pavanhu miriyoni (100,000) muvanhu vanowana chirwere ichi gore rega rega . Izvi zvinoreva kuti kunyangwe munyika yakaita seyedu, vanhu vashoma vanobatwa nechirwere ichi gore rega rega.
Chinhu chinonyanya kukosha ndechekuti Chordoma chirwere chinouraya nguva dzose. Hapana rudzi rusina kenza.
Ndezvipi zviratidzo zveizvi?
Sezvo chordoma ichikura, inoisa kumanikidzwa pauropi hwakapoteredza kana musana. Kumanikidzwa uku kunokonzera zviratidzo. Zvakare, zviratidzo zvinogona kusiyana zvichienderana nenzvimbo yebundu.
Ngationei mutafura iri pazasi kuti zviratidzo zvinosiyana sei zvichienderana nenzvimbo yebundu.
| Nzvimbo yeTumor | Zviratidzo Zvinogona Kuitika |
|---|---|
| Zviratidzo zvinowanzoonekwa | Kurwadziwa, kushaya simba, uye/kana kusanzwa simba kumusana, maoko, kana makumbo. |
| Mazita Ekutanga eDehenya | - Kuona kaviri (diplopia) - Kuona kusina kujeka - Musoro - Kunzwa kusanzwa kana kurwadziwa kwechiso |
| Pazasi pemusana (Tailbone/Sacrum) | - Bundu rinogona kunzwikwa nepaganda - Kutadza kuita weti kana kuita tsvina (kutadza kudzora muviri) - Marwadzo muhudyu kana pasi pemusana |
Sei rudzi urwu rwegomarara ruchikura? Chii chinokonzera?
Vaongorori vachiri kutadza kuziva chikonzero chaicho, asi vanotenda kuti kuchinja kwemajini kunonzi TBXT kunobatanidzwa.
Funga nezvazvo, mwana paanotanga kukura mudumbu raamai vake, musana usati wakura, mapfupa madiki anonzi notochord anoumbwa. Izvi ndizvo zvinozokura kusvika pamuzongoza. Kazhinji, notochord iyi inonyangarika zvachose mwana paanosvika mavhiki masere ekuberekwa.
Asi kashoma, mamwe emasero aya anogona kuramba ari pasi pedehenya kana mumapfupa emusana. Zvinotendwa kuti gare gare, kana paine shanduko mujini reTBXT ratakataura nezvaro, masero aya asara anogona kutanga kukura zvisingadzoreki uye kuita kenza yechondroma.
Uyewo, vanhu vane chirwere chemajini chinonzi tuberous sclerosis vari panjodzi yakakura zvishoma yekubatwa nechordoma.
Nzira yekuziva chirwere ichi? (Kuongororwa)
Kana uine zviratidzo zvakanyorwa pamusoro apa, unofanira kutanga waona chiremba wako. Chiremba achakubvunza nezvezviratidzo zvako uye nhoroondo yako yehutano. Zvadaro, vachakuongororwa muviri uye kuongororwa kwetsinga.
Kana ukafungidzira kuti une bundu rekenza, chiremba achakutumira kuti uitwe mifananidzo.
- X-ray
- Kuongororwa kweComputed Tomography (CT)
- Kuskena kweMagineti Resonance Imaging (MRI)
Mushure mekuongororwa uku, ungangoendeswa kuna chiremba ane hunyanzvi mukurapa kenza yemapfupa. Mimwe miedzo ingangodiwa kuti usimbise chirwere ichi uye kuti chionekwe kana chapararira kune dzimwe nhengo dzemuviri.
Nzira chete yekuziva zvizere nezvechirwere ichi ndeyekuita biopsy , iyo inosanganisira kutora sampuli diki yenyama kubva mubundu uchishandisa tsono diki woiongorora pasi pemaikorosikopu.
Inorapwa sei?
Kurapa kukuru uye kwakanakisa kwechordoma kuvhiyiwa. Mhedzisiro yakanakisisa kumurwere inowanikwa nekubvisa bundu rekenza rakawanda sezvinobvira (en bloc resection).
Zvisinei, izvi hazvisi nyore sezvazvinoita nekuti, sezvatakambokurukura, mabundu aya anoumba pedyo nenhengo dzakakosha uye tsinga dzinonzwa zvakanyanya.
- Mamota ari pasi pedehenya: Izvi zvakaoma kubvisa zvachose nekuti zviri pedyo nepfungwa, tsinga dzinokosha, uye mitsipa yeropa.
- Mabundu emusana: Aya anogona kupinda mumusana, tsinga, uye tsinga huru dzeropa. Kana izvi zvikakuvara panguva yekuvhiyiwa, kuremara zvachose kana kutofa kunogona kuitika.
Saka, vanachiremba vepfungwa vanoedza kubvisa bundu iri zvakanyanya sezvinobvira vasingakuvadzi murwere.
Kenza yeChordoma inowanzo tadza kupindura zvakanaka kana yashandiswa nemwaranzi uye chemotherapy, saka izvi hazviwanzo shandiswa senzira huru dzekurapa. Zvisinei, kurapwa nemwaranzi kunoitwa mushure mekuvhiyiwa kuti kuparadze masero ekenza asara uye kuderedza njodzi yekuti kenza idzoke zvakare.
Vaongorori vari kuongorora nzira dzemazuva ano dzekurapa dzakadai sekurapa kwakanangana nezvirwere uye immunotherapy.
Chii chinonzi fungidziro yechirwere ichi?
"Kufanotaura" kufanotaura mukana wekupora uye kupona kubva kuchirwere. Kana uri chirwere chechondroma, izvi zvinoenderana nezvinhu zvakati wandei:
- Nzvimbo yebundu uye kuti rakabviswa zvakadii panguva yekuvhiyiwa: Kana bundu racho rakabviswa zvachose, mhedzisiro yacho inenge iri nani.
- Kana kenza yapararira (yakapararira nemasero eropa):Kana ikapararira kune nhengo dziri kure mumuviri, mwero wekurarama kwayo unoderera.
- Zera rekuongororwa kwechirwere: Mhedzisiro inogona kunge yakaderera zvishoma kune vanhu vane makore anopfuura makumi matanhatu.
- Rudzi rwegomarara: Mhando dzegomarara dzakajairika dzine mhedzisiro iri nani pane mhando dzegomarara dzakadai se "Dedifferentiated" dzatakataura nezvadzo.
Sekureva kweimwe ongororo, mwero wekurarama kwevarwere vane chordoma ndewekuti:
- Mushure memakore matatu: 80.5%
- Mushure memakore mashanu: 68.4%
- Mushure memakore gumi: 39.2%
Asi musavhundutswa nenhamba idzi. Idzi ingori avhareji kubva kuboka guru revarwere. Mhedzisiro yenyu inogona kusiyana zvikuru zvichienderana nemamiriro enyu ezvinhu, marapirwo emuviri wenyu, uye kuti muviri wenyu unopindura sei. Chikwata chenyu chezvekurapa chete ndicho chinogona kukupai ruzivo rwakanakisisa nezvenyaya iyi. Saka musatya kuvabvunza mibvunzo.
Chirwere ichi chinogona kudzivirirwa here? Ndinofanira kuona chiremba riini?
Hapana chatingaita kudzivirira kukura kwechondroma. Zviitiko zvakawanda zvinoitika zvisina tsarukano. Kana mumwe munhu mumhuri mako aine chondroma kana tuberous sclerosis, zvakakosha kuti ugare uchiongororwa nachiremba.
Chinhu chinonyanya kukosha ndechekutevera kurapwa kwenguva refu mushure mekurapwa. Chondroma igomarara rinogona kudzoka kunyangwe mushure memakore akawanda ekurapwa. Saka, zvakakosha kuti ugare uchiongororwa sezvakataurwa nechikwata chako chekurapa.
Kana ukaona zviratidzo zvitsva kana kuti zviratidzo zvako zvikawedzera, enda kuna chiremba wako nekukasika.
Zvakajairika kuti unzwe kutya uye kuomerwa kana ukanzwa nezvegomarara risingawanzoitiki kudaro. Asi yeuka kuti timu yako yezvekurapa ichashanda newe kugadzira hurongwa hwakanakisa hwekurapa kwako uye kuita zvese zvavanogona kuti uvandudze hupenyu hwako.
Mharidzo Yekuenda Nayo Kumba
- Chordoma rudzi rwegomarara rusingawanzoitiki runokura mumapfupa emusana kana pasi pedehenya.
- Zviratidzo zvinoenderana nenzvimbo yegomarara uye zvinogona kusanganisira musoro, kuona kaviri, kurwadziwa kwemusana, uye kusanzwa simba mumakumbo.
- Kurapa kukuru kubviswa bundu nekuvhiyiwa, asi izvi zvinogona kuoma zvichienderana nenzvimbo yaro.
- Kunyangwe mushure mekurapwa, pane mukana wekuti kenza idzoke zvakare, saka kuteverwa kwenguva refu nachiremba wako kwakakosha.
- Usatye nenhamba dziripo. Murwere wega wega akasiyana. Taura nechikwata chako chekurapa kuti uwane ruzivo rwakanyatsojeka nezvemamiriro ako ezvinhu.
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