Une mavara kana mapundu asingazivikanwe paganda rako here? Izvi zvinogona kunge zviri Cutaneous B-Cell Lymphoma here?

Ganda redu chinhu chakanaka, handiti? Dzimwe nguva mapundu madiki nemavanga anouya oenda. Asi dzimwe nguva ungangove uchifungira nezvenzvimbo itsva kana bundu paganda rako, kana kuti yagara kwenguva refu isati yapora. Panguva dzakadaro, tinofanira kungwarira zvishoma. Nekuti, kunyangwe zvisingawanzoitiki, shanduko dzeganda dzakadaro dzinogonawo kuva chiratidzo chechirwere chakakomba. Nhasi tichataura nezvechirwere cheganda chisingawanzoitiki, asi chakakosha kwazvo chekuziva. Icho chirwere chinonzi cutaneous B-cell lymphoma, kana `(Cutaneous B-Cell Lymphoma)`.

Chii chinonzi Cutaneous B-Cell Lymphoma?

Zvichitaurwa zviri nyore, Cutaneous B-Cell Lymphoma (CBCL) imhando yekenza inotanga paganda rako. Hazviwanzoitiki. Inowanikwa muboka rekenza inonzi lymphoma. Asi chinhu chakakosha ndechekuti inotanga kunze kwema lymph nodes edu, muganda. Ndosaka ichinzi extranodal lymphoma.

Kazhinji, `(CBCL)` iyi inoonekwa senzvimbo, mapundu, kana bundu paganda. Izvi zvinokura zvishoma nezvishoma. Zvinogona kutora mwedzi, kunyange makore, kuti zvikure. Zvakare, hazviwanzopararira kune dzimwe nhengo dzemuviri. Vamwe vanhu vanoidaidzawo kuti `(B-cell skin lymphoma)`. Saka, kana ukaona chimwe chinhu chitsva kana chakasiyana paganda rako, zvakanaka kuti unyatsoteerera.

Lymphoma iyi inokura sei? Chii chinonzi B-cells?

Zvino ungave uchishamisika kuti sei chimwe chinhu chakadai chichiitika. Kutaura chokwadi, masayendisiti haasati awana chikonzero chaicho cheizvi '(CBCL)'. Asi chimwe chinhu chiri pachena: hachigamuchirwi senhaka kana kuti chinotapuriranwa.

Zvinotanga nemasero machena eropa anonzi malymphocytes. Malymphocytes aya nhengo dzinokosha kwazvo dzemuviri wedu wekudzivirira chirwere. Akafanana neuto rinodzivirira nyika yedu. Kune mhando mbiri huru dzemalymphocytes: T-cells neB-cells. Kana maB-cells akatanga kukura zvakanyanya pasina kudzora, chirwere ichi chinonzi B-cell lymphoma chinoitika. Zvichitaurwa zviri nyore, masero edu anopenga zvishoma uye anova masero ekenza.

Ndeapi marudzi makuru eganda reB-cell lymphoma?

Kune mhando huru ina dze "(CBCL)`` idzi. Idzi dzinopatsanurwa zvichienderana nekuti masero anotaridzika sei uchishandisa maikorosikopu. Rudzi rumwe nerumwe runogona kutaridzika zvakasiyana paganda uye runogona kuda kurapwa kwakasiyana.

1. Rudzi rwekutanga rweganda runonzi follicle centre lymphoma:

• Iyi ndiyo mhando inonyanya kuonekwa ye `(CBCL)`.
• Kazhinji, zvinoitika pamusoro, pamutsipa, kana pachipfuva/muviri.
• Zvinoita semapundu matsvuku-tsvuku, akakwidziridzwa kana mapundu paganda .
• Izvi zvakakomba zvikuru, zvichikura kwemwedzi yakawanda, pamwe makore.

2. Nzvimbo huru yeganda remukati meganda B-cell lymphoma:

• Iyi imhando inokura zvakanaka zvakare.
• Kazhinji zvinoonekwa semaronda matsvuku-tsvuku, mapundu, kana bundu .
• Kazhinji kacho zvinoitika padumbu kana mumaoko.

3. Rudzi rweB-cell lymphoma, rudzi rwegumbo, runopararira paganda:

• Iyi idiki zvishoma pane dzimwe mhando mbiri, asi ine hukasha. Izvi zvinoreva kuti inokura nekukurumidza, mumavhiki mashoma kana mwedzi.
• Kazhinji inoonekwa sebundu rimwe kana akawanda kana mapundu pamakumbo, maoko, kana pachipfuva/muviri.

4. Primary cutaneous diffuse large B-cell lymphoma, zvimwe:

• Iyi mhando isingawanzoonekwi uye ine hasha.
• Chitarisiko chinogona kusiyana, asi kazhinji chinotangira pamusoro, padumbu, uye pamigumo.

Ndiani ane mukana mukuru wekuwana chirwere ichi? Chinowanikwa kakawanda sei?

Kutaura zvazviri, chirwere ichi chinonzi ``(CBCL)`` chinogona kuitika kune chero munhu. Hapana musiyano wepabonde, hapana musiyano wezera, uye chakaonekwa chichiitika mumarudzi akasiyana. Saka, zvakaoma kufunga kuti, "Izvi hazvizoitiki kwandiri."

Asi, musavhunduka. Ichi chirwere chisingawanzoitiki. Fungai nezvazvo, kana mukawana avhareji yevanhu vanosvika miriyoni imwe chete, vana chete ndivo vachava nechirwere ichi. Saka, hamufaniri kutya muchifunga kuti ichi ndicho "(CBCL)" panguva yamunoona chimwe chinhu chisinganzwisisike paganda renyu. Zvisinei, kana muine kusava nechokwadi, kuchenjera kutsvaga mazano echiremba.

Zviratidzo zvacho ndezvipi? Ona kana uine zviratidzo izvi zvakare

Chiratidzo chikuru che `(CBCL)` kuchinja kweganda. Izvi zvinogona kuoneka nenzira dzakasiyana-siyana:

• Mapundu
• Bundu kana kuti chipundu paganda
• Bundu diki (bundu kana bundu)

Izvi zvinogona kuva zvitsvuku, zvepepuru, kana zvebrown. Zvimwe zvakasimudzwa uye zvakasimba, asi zvakatsetseka. Izvi zvinonzi ma papules. Zvimwe zvakati sandara, zvakaita semapundu eganda akakora. Izvi zvinonzi ma plaques. Mapundu makuru anonziwo ma nodules kana kuti tumors.

Panogona kunge paine bundu rimwe chete rakadaro, kana kuti pangave nerakati wandei. Zvakare, zvinogona kuonekwa panzvimbo imwe chete pamuviri kana munzvimbo dzakasiyana-siyana. Zvinogona kunge zviri pedyo nepedyo, kana kuti zviri kure nepedyo.

Fungidzirai, Sekuru Sunil vaiva nekavara katsvuku paruoko rwavo kwemwedzi yakati wandei. Vaifunga kuti kaiva kakutsvuka chete. Asi kakakura zvishoma nezvishoma kakava kabundu. Ndizvo zvinogona kuva chiratidzo chekutanga cheizvi.

Kashoma, vamwe vanhu vanogonawo kusangana nezvimwe zviratidzo. Izvi zvinonziwo "zviratidzo zveB". Izvi zvinosanganisira:

• Fivha inouya pasina chikonzero.
• Kudikitira zvakanyanya husiku.
• Kuzvimba kwema lymph nodes mumutsipa, muhapwa, kana muhudyu.
• Kuderedza uremu pasina chikonzero.

Kuvapo kwe "B features" idzi zvinoreva kuti chirwere ichi chingave chakapararira zvishoma. Zvisinei, izvi hazviwanzoitiki mu `(CBCL)`.

Vanachiremba vanoongorora sei izvi?

Vanhu vazhinji vanononoka kutsvaga rubatsiro rwechiremba nekuti mavara nemapundu anoonekwa paganda muCBCL anogona kutaridzika semapundu, kurumwa nezvipembenene, allergies, mavanga, kana zvimwe zvirwere zveganda zvakaita se eczema kana psoriasis. Zvisinei, kana uine chimwe chinhu chisingawanzoitiki paganda rako chisiri kupora, unofanira kuona chiremba, kunyanya chiremba weganda.

Chiremba achatanga aongorora ganda rako zvakakwana. Achatarisa nzvimbo dzese dzemuviri wako uye achaongorora kana paine zvisina kumira zvakanaka.

Zvadaro, kuti chirwere chiongororwe zvakanaka, "biopsy yeganda" inodiwa, zvinoreva kutora ganda diki kubva panzvimbo isina kujairika woriongorora. Ganda diki iri rinoongororwa nemaikorosikopu nenyanzvi (''pathologist'') kuti vaone kana paine masero ekenza, uye kana zvakadaro, rudzii rwawo. "Biopsy" ndiyo chete nzira yekuziva kana iri "skin lymphoma" uye rudzii rwayo.

Kuti vaone kana kenza yapararira, chiremba wenyu anogona kuraira mimwe miedzo (`miedzo yekuongorora`). Izvi zvinogona kusanganisira:

• Kuongororwa kweropa.
• Miedzo yekufungidzira yakaita seCT scan kana PET scan.
• Kuongororwa kwemapfupa emumongo.
• Kuongororwa kweLymph node.

Ngatidzidzei nezvematanho uye kupararira kwechirwere ichi.

Danho rechirwere (CBCL) ndiro rinoyera kana kenza yapararira uye kuti yapararira kusvika papi. Danho iri rinokosha zvikuru nekuti ndiro rinoona marapirwo. Chiremba wako achakutsanangurira kuti chirwere chacho chiri padanho ripi uye kuti chichakanganisa sei iwe.

• Danho 1E: "E" inomiririra "extranodal," zvichireva kunze kwelymph nodes. Padanho iri, kenza inongogara paganda chete uye haina kupararira kune imwe nzvimbo. Kana pasina zvimwe zviratidzo zve "B", zvakaita sefivha kana kudzikira uremu, izvi zvinonziwo "Danho 1AE."

Kana "CBCL" yapararira, vanachiremba vanoshandisa nzira inonzi "TNM staging system".

• Bundu (T): Bhii rekuti "T" rinoreva huwandu hwemapule, mabundu, kana mapundu paganda, kuti akakura sei, uye kuti ari kupi. Izvi zvinoverengerwa kubva pa1 kusvika pa3 (kubva pane zvishoma kusvika pane zvakanyanya kuoma).
• MaNode (N):Vara rekuti "N" rinoratidza kana ma lymph nodes akanganiswa, mangani, uye kuti ari kupi. Izvi zvinoverengerwawo kubva pa0 kusvika pa3.
• Metastasis (M): Vara rekuti "M" rinoratidza kana lymphoma yapararira kupfuura ganda kana lymph nodes (`M1`) kana kuti kwete (`M0`). `(Metastasis)` zvinoreva kuti kenza yapararira kune nhengo dziri kure.

Mishonga yacho ndeipi? Inogona kurapwa here?

Kurapwa kwe `(CBCL)` kunoenderana nerudzi rwechirwere uye danho racho. Chinowanzo poreswa, kunyanya mumhando dzakanyanya kukura. Zvisinei, dzimwe nguva chirwere chinogona 'kudzoka'.

Kune nzira dzakasiyana siyana dzekurapa:

• Kutarisa chirwere ichi: Mune dzimwe nguva apo chirwere ichi chiri kukura uye chisingakonzeri matambudziko makuru, vanachiremba vanogona kushandisa nzira yekuti "tarisai uye mirirai". Kureva kuti, vanoongorora chirwere ichi kusvika chatanga kurapwa.
• Kurapa nemakemikari: Kupa mishonga inouraya masero egomarara. Iyi mishonga inogona kutorwa semapiritsi kana jekiseni.
• Mishonga inoiswa pamusoro peganda kana kuti inobayiwa jekiseni: Mishonga yakaita secorticosteroids inogona kuiswa paganda kana kubaiwa zvakananga mubundu.
• Ma antibodies eMonoclonal: Mishonga yakaita se`(Rituximab)` iri muboka iri. Iyi inoshanda senzira yekurapa yakanangana uye inoparadza masero eB.
• Kurapa nemwaranzi: Kushandiswa kwemwaranzi ine simba guru kuparadza masero ekenza. Izvi zvinowanzo shanda pamabundu ari munzvimbo imwe chete.
• Kubviswa kweganda neoparesheni: Dzimwe nguva, kana paine bundu rimwe chete, rinogona kubviswa zvachose nekuvhiyiwa.

Chiremba wako achakurukura newe nzira yekurapa yakakunakira.

Pane nzira yekudzivirira izvi kuti zvisaitike here?

Zvinosuwisa kuti, sezvo chikonzero chaicho che `(CBCL)` chisati chazivikanwa, hapana nzira dzakasimbiswa dzekudzivirira. Saka, chinhu chakanakisa chatingaita ndechekuziva nezvekuchinja kusingawanzoitika paganda redu uye kutsvaga rubatsiro rwechiremba nekukasika kana tikaona chero chinhu.

Chii chinonzi fungidziro yekupora? (Fanidziro)

Kufanotaura chirwere, kana kuti maonero, zvinoenderana nezvinhu zvakati wandei, kunyanya rudzi rwe lymphoma uye danho rechirwere.

• Mhando mbiri dzinonyanya kuzivikanwa (`Primary cutaneous follicle center lymphoma` uye `Primary cutaneous marginal zone B-cell lymphoma`): Idzi dzine mwero wekurarama kwemakore mashanu weinenge 95%. Izvi zvinoreva kuti makore mashanu mushure mekuonekwa kwechirwere ichi, 95 pa100 evarwere ava vachiri vapenyu. Iyi itsika yakanaka kwazvo.
• Mhando dzinonyanya kurwisa (`Primary cutaneous diffuse large B-cell lymphoma, leg type` uye `other`): Idzi dzine mwero wekurarama kwemakore mashanu weinenge 60%.

Nhamba idzi dzinongova avhareji. Mamiriro ako ezvinhu anogona kunge ari nani kana kuti akaipa, saka zvakanaka kutaura nachiremba wako nezvenyaya iyi.

Ndingadzoka here mushure mekurapwa?

Ehe, lymphoma yeganda inogona kudzoka mushure mekurapwa. Mapundu anogona kudzoka panzvimbo imwe chete kana munzvimbo itsva. Kazhinji, rudzi rumwe chete runodzoka. Zvisinei, kashoma, CBCL inodzoka inogona kunge iri chirwere chemuviri kana imwe mhando yelymphoma.

Saka, zvakakosha zvikuru kugara uchiongorora ganda rako ('skin checks') uye kugara uchiongororwa nachiremba weganda kana imwe nyanzvi.

Unotarisira sei hutano hwako semunhu ane CBCL?

Kana uine chirwere (CBCL) kana kuti wakambova nacho kare ndokupora, zvakakosha kuti utevedzere mirairo yachiremba wako. Uchafanira kuramba uchiongororwa kuti uone kuti chirwere chacho hachina kudzoka zvakare.

Kuti bvunzo idzi dzinoitwa kangani zvinosiyana zvichienderana nerudzi rweCBCL uye kuti dzinorwisa sei. Dzinogona kuitwa mavhiki mashoma ega ega, mwedzi mishoma yega yega, kana kamwe chete pagore. Kuongororwa uku kunogona kusanganisira kuongororwa kweganda, kuongororwa ropa, x-ray, kana biopsy.

Mibvunzo yaunofanira kubvunza chiremba wako zvechokwadi

Kana ukaonekwa uine `(Cutaneous B-Cell Lymphoma)`, usakanganwa kubvunza chiremba wako mibvunzo iyi:

• Ndechipi chidimbu che `(CBCL)` chandinacho?
• Iri danho ripi?
• Munokurudzira rudzii rwekurapwa?
• Ndezvipi migumisiro nenjodzi dzekurapa ikoko?
• Chii chandinofungidzira kuti ndicharwara?
• Zvinotora nguva yakareba sei kuti uzive kana kurapwa kwacho kwabudirira kana kuti kwete?
• Ndinofanira kukuonai kangani kuti ndive nechokwadi chekuti lymphoma haina kudzoka?

Mhinduro dzemibvunzo iyi dzichakubatsira kunzwisisa chirwere ichi zviri nani uye matanho anotevera.

Mharidzo Yekuenda Nayo Kumba Kubva Zvatave Tichitaura Nezvedu

Rudzi rwekenza yeB-Cell Lymphoma rusingawanzoitiki runotangira mumasero anonzi malymphocytes ari paganda.

• Zvirwere zvakawanda zvinokura zvishoma nezvishoma uye hazvipararire kune dzimwe nhengo dzemuviri. Zvisinei, dzimwe mhando dzinogona kuva nehasha uye kupararira.
• Kana ukaona bundu idzva, chivara, kana mapundu asingapore paganda rako, usazviregeredza . Enda kuna chiremba, kunyanya chiremba weganda, nekukasika.
• Mhando dzakawanda dzeCBCL dzinogona kurapwa nekuonekwa nekukurumidza uye kurapwa kwakakodzera.
• Nekuti chirwere chinogona kudzoka mushure mekurapwa,Zvakakosha kuongororwa panguva dzakatarwa sezvakarairwa nachiremba.

Rangarirai kuti ruzivo urwu nderwekupa ruzivo chete. Kana muine matambudziko ehutano, zvakanaka kutsvaga mazano echiremba.

Lymphoma yeB -Cell yeCutaneous, Kenza yeGanda, Lymphoma, B-Cell, Mapundu eGanda, Chirwere cheGanda