Ungave uine dzihwa kana ronda riri kuzvimba, paunoenda kuna chiremba, vanokupa mhando dzakasiyana dzemishonga inorwisa mabhakitiriya, handiti? Mamwe anouya ari muchimiro chemakapisi, mamwe anonyungudutswa otorwa, uye mamwe anopihwa sejekiseni. Saka nhasi tichataura nezveboka rakasiyana, rakasimba zvishoma remishonga inorwisa mabhakitiriya. Aya anonzi lincosamides. Ungave usina kunzwa nezvezita iri, asi chiremba angave akakunyorera imwe yemhando idzi dzemishonga.
Zvichitaurwa zviri nyore, chii chinonzi lincosamides idzi?
MaLincosamides iboka remishonga inorwisa mabhakitiriya, kana kuti sezvatinoadaidza, mishonga inorwisa mabhakitiriya. Funga nezvawo seimwe mhando yemishonga, senge penicillin. Anoshandiswa kurapa
hutachiona hunokonzerwa nemabhakitiriya . Yeuka, haabatsiri
padzihwa nefuruu, izvo zvinokonzerwa nemavhairasi. Kune mhando dzakasiyana dzemaLincosamides dziri kushandiswa pari zvino.
- Clindamycin: Iyi ndiyo lincosamide inonyanya kushandiswa pakati pedu. Vanachiremba vanokurudzira kuti ishandiswe pazvinhu zvakawanda, zvinosanganisira hutachiona hweganda , mapundu, uye matambudziko emadzimai .
- Lincomycin: Kunyangwe yaishandiswa kare, ikozvino haichanyanyi kushandiswa.
- Pirlimycin: Iyi haipiwi kuvanhu, asi inoshandiswa mukurapa mhuka.
Mushonga uyu unopinzwa sei mumuviri?
Nzira yaunopa mushonga uyu inosiyana zvichienderana nemamiriro ako ehutano. Unogona kushandisa imwe neimwe yeiyi nenzira yayo.
| Nzira yakashandiswa | Tsananguro iri nyore |
|---|
| Kunwa nemuromo | Tora sema capsules, mapiritsi, kana mvura. |
| Pamusoro penyaya | Kuisa kirimu, gel, kana mvura pamusoro peganda (semuenzaniso, pamapundu). |
| Mutsinga dzetsandanyama | Kubaiwa jekiseni pafudzi kana pamatako. |
| Nemutsinga (IV) | Jekiseni muropa. Nzira iyi inoshandiswa kana paine hutachiona hwakakomba. |
| Kupinza munhengo yemukadzi (Intraginally) | Inoshandiswa sekirimu kana piritsi rekudzivirira hutachiona hwepanhengo yekubereka. |
Ndeapi marudzi ehutachiona anorapwa ne lincosamides?
Rudzi urwu rwemishonga runonyanya kutarisana nemhando mbiri dzemabhakitiriya. 1.
Mabhakitiriya ane Gram-positive: Funga nezvayo se "Gram stain". Iri iboka remabhakitiriya anosvibisa bhuruu/pepuru uye ane madziro emasero akakosha. 2.
Mabhakitiriya asina simba: Aya akakosha zvikuru. Nekuti anogona kurarama nekukura
kunyangwe munzvimbo dzisina oxygen . Semuenzaniso, anogona kuwanikwa mumaronda akadzika, akakomberedza matadza, uye mukati medumbu. Nekuda kwechikonzero ichi, vanachiremba vanowanzo kurudzira rudzi urwu rwemushonga kune zvirwere zvakaita se:
- Zvirwere zveganda nenyama yakapfava: Kune zvirwere zveganda zvakaita semapundu ne cellulitis.
- Utachiona hweMRSA: `Methicillin-resistant Staphylococcus aureus (MRSA)` ibhakitiriya rakakura risingaurayiwe nemishonga yakawanda inorwisa mabhakitiriya. MaLincosamides anowanzo shandiswa kurapa.
- Utachiona hwemuromo nemazino: Utachiona hwakanyanya hwemazino nemidzi yemazino.
- Utachiona hwevakadzi: Kune zvinhu zvakaita sechirwere chemuchiuno chinozvimba (PID).
- Pumbu: Chirwere chekuti mapundu akaita semapundu anoumbwa mukati memapapu.
- Utachiona hweropa: Matambudziko akakomba anokonzerwa nehutachiona hunopinda muropa, senge septicemia.
- Mapundu akakomba: Kune zvirwere zvepundu zvakakomba zvisingapindure kurapwa kwakajairika.
- Maronda emudumbu akadzika: Kumisa kupararira kwehutachiona muzviitiko zvekukuvara kwemudumbu, senge maronda ekubaiwa nebanga.
- Kune vanhu vane HIV vane pneumonia nechirwere chemwoyoIzvi zvinoshandiswawo kudzivirira endocarditis.
Chinhu chinonyanya kukosha ndechekuti mushonga uyu ushandiswe pazvirwere zvakaoma uye zvakakomba zvisina kupindura kune mamwe maantibiotic ari nyore.
Mushonga uyu unoshanda sei?
Zviri nyore kwazvo. Kuti mabhakitiriya akure uye apararire, anofanira kugadzira mapuroteni. Zvinoitwa ne lincosamides
kumisa mabhakitiriya kugadzira mapuroteni aya . Zvakafanana nekubvisa simende pakuvaka imba. Kana mabhakitiriya asingakwanise kugadzira mapuroteni, haakwanise kukura, uye dzimwe nguva anofa. Saka mushonga uyu une simba rekumisa kukura kwemabhakitiriya (bacteriostatic) uye simba rekuparadza mabhakitiriya zvachose (bacteriacidal).
Ndezvipi zvingakonzera migumisiro yakaipa?
Kufanana nemishonga chero ipi zvayo, lincosamides inogona kukonzera migumisiro yakaipa, uye matambudziko ekugaya ndiwo anonyanya kuitika.
Migumisiro inowanzoonekwa Zviratidzo zvakakomba zvinofanira kuziviswa kuna chiremba nekukasika
| Rudzi rwemhedzisiro yakaipa | Hunhu |
|---|
| Matambudziko ekugaya chikafu | Kurwadziwa kwemudumbu, kuda kurutsa uye kurutsa, manyoka (kuzvimba). |
| Zvimwe zvirwere zvidiki | Dzungu , kuneta, kubuda ropa kubva muchibereko kana kuvaviwa. |
| Manyoka akanyanya | Manyoka ane ropa kana kuti akawandisa. |
| Kutadza kufema zvakanaka (Dyspnea) | Kufema zvishoma kana kunzwa kubatwa muchipfuva. |
| Mapundu eganda | Mapundu, maronda, kana kuvaviwa zvinopararira mumuviri wese. |
| Kuoma kumedza (Dysphagia) | Kunzwa kubatwa kana kurwadziwa pahuro kana uchimedza chikafu kana chinwiwa. |
| Jaundice | Kutsvuka kwemaziso neganda. |
Pane njodzi dzakakomba here?
Ehe, kunyangwe zvisingawanzoitiki, kune dzimwe njodzi dzakakomba dzinogona kuitika nemushonga uyu. Zvakakosha kuziva izvi.
- Pseudomembranous colitis: Ichi ndicho chirwere chakakomba chinokonzerwa ne lincosamides. Mushonga uyu unoparadza mabhakitiriya akanaka muura uye unobvumira kukura kwebhakitiriya rakaipa rinonzi Clostridium difficile. Izvi zvinogona kukonzera manyoka ane ropa, fivha, uye kurwadziwa mudumbu.
- Anaphylaxis: Kurwara kwakanyanya kunogona kuisa upenyu panjodzi.
- Stevens-Johnson syndrome (SJS): Iyi idambudziko guru, rinouraya vanhu. Ganda rinoputika uye rinobuda, sekunge rapiswa.
- Kukuvara kwechiropa kana itsvo.
Kana ukaona chimwe chezviratidzo izvi zvakakomba, rega kutora mushonga uye enda kuna chiremba wako nekukasika . Kana zvichidikanwa, usazeza kuenda kuEmergency Department (ETU).
Zvinhu zvekurangarira kana uchishandisa mushonga uyu
- Madzimai ane pamuviri uye anoyamwisa: Kana uine pamuviri, uchiedza kuva nepamuviri, kana kuti uchiyamwisa, unofanira kuudza chiremba wako usati watora mushonga uyu.
- Zvimwe zvirwere: Kana uine chirwere chechiropa, itsvo, kana chemudumbu (semuenzaniso chirwere cheCrohn ), zivisa chiremba wako nezvazvo zvakare.
- Mimwe mishonga: Udza chiremba wako nezvemimwe mishonga yauri kutora, kunyanya mimwe mishonga inorwisa mabhakitiriya. Mimwe mishonga inogona kushanda pamwe chete.
- Chipimo: Inwa mushonga sezvawakarairwa nachiremba wako, kwenguva yese. Usarega kutora mushonga nekuti zviratidzo zvako zvadzikira. Kuita izvi kunogona kukonzera kuti hutachiona hudzoke zvakare.
- Chirwere cheshuga neshuga yeropa: Imwe tsvakiridzo yakaratidza kuti panogona kunge paine hukama pakati pekushandiswa kwe lincosamide nenjodzi yekubatwa nechirwere cheshuga. Zvisinei, izvi hazvisati zvanyatsojeka. Kana uine chirwere cheshuga, taura nachiremba wako nezvazvo futi.
Mharidzo Yekuenda Nayo Kumba
- MaLincosamides rudzi rwemishonga inorwisa mabhakitiriya ine simba inoshandiswa kurapa hutachiona hwakakomba husingarapike nemishonga yechinyakare.
- Zvakakosha kutora mushonga wakanyorwa kwenguva yakatarwa sezvakarairwa nachiremba wako. Pedzisa mushonga kunyangwe zviratidzo zvako zvikadzikira.
- Zvikanganiso zvidiki zvakaita sekurwadziwa kwemudumbu nemanyoka zvinogona kuitika. Zvisinei, kana ukaona zviratidzo zvakaita semanyoka ane ropa, kunetseka kufema, kana mapundu eganda akanyanya, enda kuna chiremba nekukasika.
- Udza chiremba wako nezvemimwe mishonga yauri kutora uye chero zvimwe zvirwere zvaunazvo (kunyanya matambudziko echiropa, itsvo, kana ura) usati wanyora mushonga wacho.
- Usagovane mushonga uyu nemumwe munhu kana kushandisa chero mushonga wasara. Gara uchishandisa mushonga uyu chete sezvawakarairwa nachiremba wako.
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