Unewo chirwere cheAlzheimer chisati chatanga here? Ngatidzidzei nezvazvo!

Dzimwe nguva unofunga here kuti, "Mazuva ano ndiri kukanganwa zvese"? Kana kuti wakaona shanduko diki mundangariro kana maitiro eshamwari yako here? Pamwe zvinhu izvi hazvisi zvekunetseka nazvo. Zvisinei, kana zvinhu izvi zvikaramba zvichiitika kunyangwe usati wakura, zvakanaka kuzviongorora zvishoma. Kunzwa zvinhu izvi kunogona kunetsa zvishoma, asi chinonyanya kukosha kuziva izvi.

Chii chinonzi Early-Onset Alzheimer's Disease?

Zvichitaurwa zviri nyore, Early-Onset Alzheimer's Disease (EOAD) imhando yechirwere cheAlzheimer's chinokura muvanhu vari pasi pemakore makumi matanhatu nemashanu. Vanachiremba dzimwe nguva vanoti chirwere cheAlzheimer's chinoitika vachiri vadiki . Kazhinji, zviratidzo izvi zvinotanga kuonekwa pakati pemakore makumi mana nemashanu nemakumi matanhatu nemana.

Chirwere cheAlzheimer chirwere chinoparadza tsinga dzeuropi . Kureva kuti, chirwere chinokuvadza nekuparadza masero ari muuropi hwedu nekufamba kwenguva. Ichi ndicho chikonzero chikuru chedementia , inova kurasikirwa nendangariro nehungwaru zvishoma nezvishoma. Zvisinei, vasingasviki 1% yevarwere vese vane Alzheimer vanotambura nedementia yekutanga (EOAD).

Pakutanga, ungaomerwa nekuona shanduko dziri mauri. Asi avo vari pedyo newe, semhuri yako neshamwari, vanogona kuona shanduko dzisiri pachena dzaungasaone. Kana ukaona shanduko dziri mundangariro dzako, mafungiro ako, kana mashandiro ako ezuva nezuva, enda kuna chiremba nekukasika.

Ndezvipi zviratidzo zveAlzheimer's yekutanga?

Zviratidzo zvechirwere cheAlzheimer chagara chiripo zvakafanana zvikuru nezvirwere zveAlzheimer. Musiyano mukuru izera iro zviratidzo izvi zvinotanga kuoneka. Chirwere ichi chinokonzera kudzikira zvishoma nezvishoma kwehunyanzvi hwepfungwa (progressive cognitive decline) . Izvi zvinoreva kuti sezvo uropi hunokuvadzwa, zviratidzo zvinowedzera nekufamba kwenguva.

Pakutanga, ungazviwana zvakaoma kuziva zviratidzo izvi iwe pachako. Asi vadikanwi vako, mhuri yako, vanogona kuona shanduko diki idzi. Kana iwe kana mumwe munhu waunovimba naye akaona chimwe chezviratidzo izvi zvekushaya pfungwa, zvakakosha kutaura nachiremba.

Chirwere ichi (EOAD) hachibate munhu wese nenzira imwe chete. Asi kazhinji, chinogona kukanganisa:

• Ndangariro
• Unyanzvi hwemutauro - kutaura nekunyora
• Kugona kufunga
• Maitiro uye hunhu
• Kuziva nezvenzvimbo - Semuenzaniso, kunzwisisa nzvimbo.

(EOAD) Zviratidzo zvinowanzotanga zvishoma uye zvinotowedzera kuipa nekufamba kwenguva. Pakutanga, unogona kuona shanduko diki dzakadai sedzinotevera:

• Kuchinja kwemaitiro ako kana hunhu hwako (kunyanya kuva nehasha, kutsamwa, kana kutsamwa kupfuura kare)(Zvingawedzera.) Fungidzira, mumwe munhu aimbove akadzikama zvikuru iye zvino ava kugumbuka nezvinhu zvidiki.
• Kuomerwa nekuwana mazwi akakodzera pakutaura kana kunyora. Zvinoita sekunge mashoko haasi kubuda mumuromo mako.
• Kurasikirwa nendangariro (semuenzaniso, kukanganwa mazita evanhu, zviso, kana zviitiko zvakaitika panguva iyoyo). Unowanzo kanganwa runyorwa rwezvinhu zvawakaudzwa kuti uuye nazvo here? Kana kuti unongoerekana wakanganwa zvawaizotaura pahurukuro?
• Zvakaoma kugadzirisa matambudziko aunowanzogona kugadzirisa zviri nyore.
• Kunyangwe zvazvo mirairo yakapihwa (sekubika zvinoenderana neresipi) , zvinogona kuoma kutarisa pane zvekuita zvinotevera uye kuita sarudzo .
• Matambudziko ekuona, kuenzana, uye kubatana (ungazviwana uchigara uchingogumburwa nefenicha kana kugumburwa).

Gare gare, unogona kuona zviratidzo zvakakomba, zvakaita se:

• Kukanganwa kuti uri kupi uye kuti wakasvika sei ikoko .
• Zvakatoipa zvikuru kurasikirwa nendangariro (kusvika pakuti unotokanganwa zvikamu zvendangariro yako yenguva refu).
• Kufungirana uye kusavimba nevadikanwi (kunyangwe avo vaunoti unovaziva zvakanaka).
• Kurasikirwa zvishoma (kana zvachose) kwekugona kutaura nekukurukura.

Ndezvipi zvikonzero zveAlzheimer's yekutanga?

Chikonzero chikuru chechirwere cheAlzheimer chisati chasvika nguva ndeyekuiswa kwemapuroteni muuropi zvisina kujairika , kunyanya mhando mbiri dzemapuroteni anonzi amyloid netau .

Unoziva, uropi hwedu hune mabhiriyoni emasero etsinga anonzi ma neuron . Masero aya etsinga ndiwo anotibatsira kufunga, kudzidza, kurangarira, uye kuronga. Saka, puroteni ye amyloid inonamatirana mukati memasero europi, ichigadzira ma clumps anonzi ma plaques . Mapuroteni eTau anobatana pamwe chete, achiumba ma tangles . Ma plaques aya ne tangles zvinodzivirira masero etsinga kushanda zvakanaka. Anovhara masaini emagetsi nemakemikari anopfuura nepakati pawo.

Kana mapuroteni e-amyloid ne-tau akaungana muuropi, anouraya masero etsinga zvishoma nezvishoma. Izvi ndizvo zvinokonzera kukuvara kusingaperi kunokonzera zviratidzo zvechirwere cheAlzheimer. Masero etsinga anotanga kufa mune chimwe chikamu cheuropi, ozopararira kune zvimwe zvikamu. Kazhinji, EOAD inotanga muchikamu cheuropi chinodzora ndangariro dzedu - hippocampus .

Nyanzvi dzichiri kuedza kutsvaga kuti sei mapuroteni aya achiungana. Vaongorori vanofunga kuti kuungana uku kwemapuroteni kunoitika kare zviratidzo zvisati zvaonekwa. Zvinogona kutora makore gumi usati watanga kuona zviratidzo.

Ko chirwere cheAlzheimer chinokonzerwa nemajini here?

Ehe, chirwere cheAlzheimer chinoitika nguva isati yakwana chirwere chinokonzerwa nemajini.Zvinogoneka. Zvizhinji zvezvirwere izvi (chirwere cheAlzheimer's chepakutanga ) zvakawanikwa zvichibatanidzwa nekuchinja kwemajini mumachromosomes 1, 14, kana 21. Zvakare, kuva nejini rinonzi (APOE e4 gene) kunowedzera njodzi. Asi havasi vese vane jini re (APOE e4) vachawana chirwere cheAlzheimer's. Ndicho chinhu chimwe chete chinogona kuwedzera njodzi yacho.

Chirwere cheAlzheimer chinogonawo kuitika mumhuri. Izvi zvinoreva kuti kana vabereki vako kana vanun'una vako vaine chirwere ichi, uri panjodzi huru yekuchibata. Kana vaviri vevanun'una vako kana vabereki vako vese vaine chirwere ichi, njodzi yako yakakura.

Ndezvipi zvinhu zvinokonzera njodzi?

Vatsvakurudzi vachiri kudzidza nezvezvikonzero zvinokonzera chirwere cheAlzheimer kukura panguva yezera iri. Zvimwe zvinhu zvinogona kukonzera njodzi zvinosanganisira:

• Kuva nechirwere cheAlzheimer mumhuri yepedyo (vabereki, vanun'una kana hanzvadzi).
• Zvinhu zvakatipoteredza (chimwe chinhu chiri munharaunda yaunogara, unoshanda, kana yaunogara uchigara).
• Kukuvara kwakanyanya mumusoro (kukuvara kwehuropi kunorwadza) .
• Kusvuta.
• Hutano hwako hwese.

Mamwe matambudziko ehutano anogona kuwedzera njodzi yeAlzheimer's, kusanganisira:

• Chirwere chemwoyo
• Chirwere cheshuga
• Down syndrome inokonzerwa ne (Trisomy 21)
• Kukwira kweropa
• Kolesteroli yakakwira
• Kufuta

Ndezvipi zvinetso zvinokonzerwa neAlzheimer's yekutanga?

Dambudziko guru rinokonzerwa nechirwere cheAlzheimer's chinoitika munhu asati aberekwa kukuvara kwachinokonzera kuuropi hwako. Chinogona kukonzera shanduko dzisingaperi pamafungiro ako, mashandisiro aunoita muviri wako, uye hunhu hwako. Sezvo chirwere ichi chichienderera mberi, unogona kusangana nematambudziko, mamwe acho anogona kuisa hupenyu panjodzi.

Izvi zvinogona kuonekwa sematambudziko:

• Kuora kwehutano hwemuviri.
• Utachiona (semuenzaniso , pneumonia kana hutachiona hweganda).
• Kubatwa nepfungwa dzakaipa .
• Kutadza kufema zvakanaka.
• Kuoma kumedza.

Kana usingakwanise kudzora muviri wako, unogona kuva panjodzi huru ye:

• Zvironda zvepamubhedha .
• Kushaya mvura mumuviri kana kushaya chikafu chakakwana .
• Kudonha, kutyoka mapfupa, uye mamwe maronda akakomba.
• Kutadza kudzora weti uye kusakwanisa kudzora ura .
• Kuora kwezino, maburi, nezvimwe zvinetso zvemazino.

Chirwere cheAlzheimer cheEarly-Onset chinowanikwa sei?

Vanachiremba vanoongorora EOAD nenzira imwe chete yavanoongorora nayo chirwere cheAlzheimer. Vanoita ongororo yakakwana yemuviri uye bvunzo yetsinga.Zvadaro, vanobvisa zvimwe zvirwere zvinogona kukonzera matambudziko akafanana ekurangarira nezvimwe zviratidzo.

Chiremba wako achakubvunza mibvunzo kuti anzwisise hutano hwako nehupenyu hwako hwezuva nezuva. Vachataurawo newe nezve shanduko dzaungasaona, asi dzakaonekwa nemumwe munhu ari pedyo newe. Chiremba wako anogona kubvunza nezve:

• Hutano hwako hwese.
• Nhoroondo yako yezvekurapa .
• Ndeipi mishonga kana ma supplements auri kutora parizvino?
• Kuchinja kwemanzwiro ako, maitiro ako, uye hunhu hwako.
• Kugona kwako kuita mabasa ako emazuva ese.

Chiremba achaitawo bvunzo dzakati wandei dzakadai se:

• Miedzo yekuziva .
• Kuongororwa kweCT .
• Kuongororwa kweMRI yeuropi .
• Kuongororwa kwePET .
• Kuongororwa kweropa.
• Kuongororwa kweweti.

Hapana bvunzo imwe chete inogona kusimbisa kana kuona chirwere cheAlzheimer chisati chatanga. Zvisinei, neruzivo rwakaunganidzwa kubva mubvunzo imwe neimwe iyi, chiremba anogona kubvisa zvimwe zvirwere zvinogona kukonzera zviratidzo zvakafanana.

Ndeipi mishonga yekurapa chirwere cheAlzheimer chisati chatanga?

Chiremba wako achakurudzira kurapwa kunononotsa kufambira mberi kwechirwere chako chepfungwa , icho chiri kurasikirwa nendangariro nehungwaru. Hapana mushonga wechirwere cheAlzheimer's . Zvisinei, kurapwa kunogona kubatsira kudzora zviratidzo uye kunonotsa kufambira mberi kwechirwere.

Kutanga kurapwa nekukurumidza ndiyo nzira yakanakisisa yekuchengetedza hutano hwehuropi muhupenyu hwako hwese. Zvisinei, hapana kurapwa kuripo kunogona kudzosera shure kukuvara kwehuropi kana kudzikira kwepfungwa.

Chiremba wako angangonyora mishonga yakajairika yeAlzheimer's yeEOAD. Ungangoda mishonga yakaita seiyi:

• (Mishonga inodzivirira cholinesterase)
• (Donanemab)
• (Lecanemab)
• (Vapikisi veNMDA)

Aducanumab mushonga mutsva weEOAD. Nyanzvi dzichiri kudzidza nezvawo. Inoderedza mapuroteni e-amyloid anoungana muuropi.

Mishonga yekudzora zviratidzo chaizvo

Chiremba wako anogonawo kukupa mushonga wekudzivirira zvimwe zviratidzo. Semuenzaniso:

• Mishonga yekuderedza kushungurudzika : Mishonga iyi inogona kurapa zvinhu zvakaita sekuzvidya mwoyo, kusagadzikana, kuchinja-chinja kwemanzwiro, uye kuora mwoyo.
• (Mishonga yekurwisa pfungwa (neuroleptics)) : Izvi zvinogona kukonzera kutya, kuona zvinhu zvisipo, uye kushushikana.Zvinhu zvakadaro zvinogona kurapwa.
• (Mishonga yekudzivirira pfari) : Mishonga iyi dzimwe nguva inogona kurapa kushanduka-shanduka kwemanzwiro.

Miedzo yekiriniki

Masayendisiti anogara achitsvaga EOAD uye mishonga inogona kutorwa. Bvunza chiremba wako kana paine miedzo yekiriniki inogona kukubatsira. Iyi miedzo kana zvidzidzo zvinosanganisira vanozvipira vane chirwere cheAlzheimer's chisati chatanga. Izvi zvinogona kukupa mukana wekuedza mishonga mitsva isati yawanikwa zvakanyanya.

Munhu ane chirwere cheAlzheimer's anotanga kurwara kwenguva yakareba sei anofanira kurarama hupenyu hwakadii?

Chirwere cheAlzheimer chisati chasvika nguva chinokanganisa munhu wese zvakasiyana. Vamwe vanhu vanorarama kwemakumi emakore. Vamwe vanofa mukati memakore gumi mushure mekuonekwa kuti vane chirwere ichi. Kureba kwenguva yaunogona kurarama kunoenderana nezvinhu zvakaita se:

• Mwero uri kudzikira kugona kwako kufunga (kudzikira kwekufunga) .
• Zera rako pawakaongororwa chirwere ichi.
• Hutano hwako hwese pamwe nezvimwe zvirwere zvaungave nazvo.

Chirwere cheAlzheimer chinokurumidza kukura chinowanzo wedzera nekukurumidza kupfuura chirwere cheAlzheimer chakajairika. Izvi zvinoreva kuti unogona kutanga zviratidzo zvakakomba nekukurumidza kupfuura munhu akaonekwa mushure memakore 65. Taura nachiremba wako nezvekurarama nechirwere cheAlzheimer chinokurumidza kukura (EOAD). Iye anogona kukubatsira kuisa zvinangwa zvinokwanisika uye zvaunotarisira.

Unoita sei kuti urarame nechirwere cheAlzheimer's chisati chatanga?

Kurarama nechirwere cheAlzheimer chisati chatanga kunogona kuoma zvikuru. Vanhu vanotanga chirwere cheAlzheimer chisati chatanga (EOAD) vanowanzova vachiri kushanda, uye vanogona kunge vaine mhuri dzechidiki dzine vana vadiki . Izvi zvinogona kukonzera matambudziko ayo vanhu vane chirwere cheAlzheimer chisati chatanga vasingasangana nawo. Izvi zvinogona kuva dambudziko guru, asi yeuka, hausi wega parwendo urwu.

Une kodzero yekutsvaga rubatsiro rwaunoda kubasa kwako. Chiremba wako anogonawo kukuudza nezvezvimwe zvinhu zvinogona kukubatsira. Unogona kutanga kuronga remangwana zviratidzo zvako zvisati zvanyanya kuipa. Semuenzaniso, ungangoda kufunga nezvemirairo yepamusoro , zvirongwa zvemutemo uye zvemari.

Kana uchida rubatsiro, taura nenyanzvi yehutano hwepfungwa . Zvakajairika kuti vanhu vane chirwere cheAlzheimer's chisati chatanga pamwe nemhuri dzavo vanzwe kushushikana, kuzvidya mwoyo, uye kusuruvara zvakanyanya , kunyanya mushure mekuonekwa kuti vane chirwere ichi. Manzwiro iwayo ndeechokwadi uye ane musoro, asi haafanire kudzora hupenyu hwako. Nyanzvi yehutano hwepfungwa inogona kukubatsira kunzwisisa mafungiro ako nemanzwiro ako uye kukubatsira kurarama nawo.

Ndinofanira kuona chiremba rini?

Kana ukasangana nematambudziko nepfungwa dzako kana kufunga, enda kuna chiremba nekukasika .

Uchafanira kuongororwa nachiremba wako nguva nenguva. Iye achaongorora kufambira mberi kwechirwere chako uye achagadzirisa marapirwo ako sezvinodiwa.

Unogonawo kubvunza chiremba wako mibvunzo yakaita seiyi:

• Ndezvipi zviratidzo kana shanduko zvatinofanira kutarisa nemhuri yangu?
• Pane nzira here yekufungidzira kuti chirwere ichi chichakurumidza sei kukura?
• Ndeipi nzira yakanakisisa yekurapa?
• Mungandipa mazano here ekubatsira mhuri yangu kuti ijairane nemamiriro ezvinhu aya?

Munhu wese anokanganwa zvinhu zvidiki nguva nenguva, kana kuti anongoerekana akanganwa zvaaida kutaura paanenge achitaura. Hazvisi zvekunetseka nazvo. Hapana anoziva pfungwa dzako nemuviri wako kupfuura iwe. Asi kana uchinetseka kuti ndangariro dzako kana kufunga kwako kuri kuchinja zvakanyanya—kunyanya kana zvichingoitika kamwe kamwe—ona chiremba.

Saka, ndezvipi zvinhu zvinonyanya kukosha zvatinoda kudzidza kubva munyaya ino?

Chirwere cheAlzheimer chinowanzoitika panguva yekukurumidza chirwere chakakomba chinogona kubata vanhu vari pasi pemakore makumi matanhatu nemashanu. Zvakakosha kutsvaga rubatsiro rwechiremba nekukasika kana ukaona zviratidzo zvepakutanga zvakaita sekukanganwa, kunetseka kuwana mazwi, uye kuchinja maitiro .

Kunyange hazvo pasina mushonga wechirwere ichi, kuongororwa nekukurumidza uye kurapwa kunogona kubatsira kudzora zviratidzo uye kunonoka kufambira mberi kwechirwere. Yeuka, hausi wega. Kune vanachiremba, nyanzvi dzehutano hwepfungwa, uye mapoka ekutsigira anogona kukubatsira iwe nemhuri yako kutarisana nedambudziko iri.

Chengetedza hutano hwehuropi hwako. Kana ukaona shanduko, usadziregeredza.

` Alzheimer's, kukanganwa, ndangariro, chirwere cheuropi, chirwere chetsinga, dementia, EOAD