Chii chinonzi Gastrin? Chinokanganisa matambudziko emudumbu mako here?

Wakambozvibvunza here kuti zvinhu zvingani zvinoitika mumiviri yedu, kunyanya mushure mekudya? Tine boka remakemikari madiki mumiviri yedu anobatsira kuti zvese izvi zviitike. Tinodaidza mahormone aya. Nhasi tichataura nezveimwe hormone yakakosha kudaro. Ndiyo gastrin. Gastrin iyi yakakosha zvikuru pakushanda kwegadziriro yedu yekugaya chikafu.

Chii chaizvo chinoitwa neGastrin?

Zvakanaka, ngationei kuti shamwari iyi inonzi Gastrin inoita sei pamiviri yedu. Ine mabasa makuru akati wandei.

• Kugadzirwa kweasidhi mudumbu: Chinhu chakakosha ndechekuudza dumbu rako kuti ribudise asidhi mudumbu. Asidhi iyi yemudumbu ndiyo yatinodaidza kuti hydrochloric acid. Pasina izvi, zvakaoma kugaya chikafu.
• Kushanda kwetsandanyama dzemudumbu: Gastrin inobatsirawo tsandanyama dziri mudumbu mako kuti dzishande zvakanaka, zvinoreva kuti inokonzera kufamba kwemudumbu, izvo zvinobatsira kusanganisa nekupwanya chikafu.
• Gadzirisa Madziro Edumbu: Rutivi rutete rwedumbu redu, mucosa, runofanira kugara ruchivandudzwa. Gastrin inobatsirawo neizvi.
• Kukurudzirwa kwenyongo nepancreas: Gastrin, pamwe chete nerimwe hormone rinonzi cholecystokinin, zvinobatsira gallbladder yako nepancreas kukwenya nekuburitsa muto wekugaya.

Chii chinosiyanisa Gastrin neGastric acid?

Izvi zvinonzwika kunge zvinovhiringidza here? Zvichitaurwa zviri nyore, zvakaita seizvi. Gastrin ihormone . Zvakafanana netsamba. Tsamba iyi inoudza dumbu kuti, "Zvakanaka, zvino buritsa acid yemudumbu." Zvadaro acid yemudumbu iyi inomutsa enzyme yekugaya pepsin. Pamwe chete, izvi zviviri zvinogadzira muto wemudumbu mudumbu medu. Unonzwisisa here?

Gastrin inogadzirwa kupi?

Gastrin inogadzirwa zvakanyanya nenhengo dziri mudumbu redu. Hormone iyi inobva kurudzi rwesero runonzi G-cells. Bhii "G" rinomiririra "gastrin."

Gastrin yakawanda inobva mudumbu rako , kunyanya chikamu chezasi chedumbu rako (tinochidana kuti antrum). MaG-cell aya ari mumagland emudumbu ari mumadziro edumbu rako. Pamusoro pezvo, rimwe gastrin rinogadzirwa neduodenum, chikamu chekutanga cheura hwako hudiki, uye nepancreas.

Ndezvipi zvinhu zvinokanganisa kuburitswa kwegastrin?

Zvinoshamisa kuti gastrin inoburitswa sei kana uchifunga nezvekudya! Unozviziva sei izvozvo? Uropi hwedu nehurongwa hwekugaya zvekudya zvinogara zvakabatana kuburikidza ne network yetsinga dzinonzi vagal nerves. Ruzivo runofamba ruchidzoka nekudzoka kuburikidza netsinga idzi.

Saka, paunofunga nezvechikafu, tsinga dzemudumbu dziri muuropi hwako dzinotumira shoko kudumbu, richiti, "Zvakanaka, chikafu chiri kuuya, sunungura gastrin uye gadzirira kugaya." Zvadaro, paunotanga kudya, tsinga dziri mudumbu mako dzinoziva kuti chikafu chapinda uye dzinoburitsa gastrin yakawanda.

Zvimwe zvinhu zvinokurudzira kuburitswa kwegastrin:

• Kuwedzera kwepH yemudumbu (ndiko kuti, kana acidity yadzikira).
• Madziro edumbu anodhonzwa kana chikafu chichipinda.
• Zvimwe zvekudya , kunyanya zvine mapuroteni, zvinopinda mudumbu.

Gastrin inokonzera kuburitswa kweasidhi yemudumbu, iyo inoita kuti pepsin ishande. Pamwe chete, izvi zvinopwanya uye zvinogaya mapuroteni ari mudumbu. Gastrin inokurudzirawo kufamba kwemhasuru dziri mudumbu.

Ungamisa sei kuburitswa kwegastrin?

Sezvo chikafu chinobuda mudumbu mako chopinda muchikamu chekutanga cheura hudiki, duodenum, danho rinotevera rekugaya rinotanga. Ndipo panotanga kuburitswa gastrin. Sezvo chikafu chichibuda mudumbu uye mazinga easidhi mudumbu anowedzera, gastrin inoderera.

Kana chikafu chikapinda muduodenum, gallbladder yako nepancreas zvinoburitsa muto wazvo wekugaya. Zvadaro, sisitimu yedu yekugaya inoburitsa imwe hormone inonzi somatostatin. Iyi somatostatin inodzima mamwe mahormone (senge gastrin). Zvakafanana nekudzima switch.

Nzira yekuongorora huwandu hwegastrin?

Pane kuongororwa kweropa kwakakosha kuti uone huwandu hwemudumbu mako. Tinokudana kuti bvunzo yemudumbu. Mupi wehutano, akadai sachiremba kana mukoti, anotora ropa diki kubva mutsinga iri muruoko rwako oritumira kurabhoritari kuti riongororwe.

Sei gastrin yangu yakakosha?

Vanachiremba vanoongorora huwandu hwemudumbu wako kuti vaone kana hwakanyanya kukwira . Hunhu hwakaderera hwemudumbu hauwanzoitiki, asi huwandu hwakanyanya hwemudumbu hunogona kuratidza zvimwe zvirwere zvemudumbu.

Zvinorevei kuwedzera kwehuwandu hwemudumbu (Hypergastrinemia)?

Kana huwandu hwegastrin hwakwira, tinohudaidza kuti hypergastrinemia. Dzimwe nguva, hypergastrinemia inogona kureva kuti une bundu rinogadzira gastrin mumuviri wako, rinonzi gastrinomas. Izvi zvinogona kuitika mupancreas kana duodenum.

Dzimwe nguva, hypergastrinemia inogona kureva kuti pane chimwe chinhu chiri mudumbu mako chiri kuidzivirira kugadzira acid yemudumbu. Kana acid yemudumbu yaderera, gastrin yakawanda inoburitswa. Uyewo, zviratidzo zvinowanzo misa kugadzirwa kwegastrin zvinokanganiswa.

Chii chinoitika kana huwandu hwegastrin hukawedzera?

Kana gastrin yako yakakwira, huwandu hweasidhi yemudumbu mako neduodenum hunogona kukwira zvakanyanya. Asidi yakawandisa inogona kukanganisa jira rekudzivirira remudumbu mako neduodenum, zvichikonzera maronda, anozivikanwawo sechirwere chepeptic ulcer.

Uyewo, kuva neacid yakawanda mudumbu kunogona kukonzera chirwere chinonzi GERD (Gastroesophageal Reflux Disease), chinova chirwere chenguva refu apo acid inokwira muhuro. Kana uine chirwere chepeptic ulcer kana GERD uye zvikasapera nemishonga, chiremba wako anogona kutarisa huwandu hwegastrin yako.

Ndezvipi zvirwere zvinogona kukonzerwa nekuwedzera kwehuwandu hwemudumbu?

Kana uine gastrinomas, huwandu hwegastrin negastric acid zvinogona kunge zvakakwira. Gastrinomas rudzi rwepancreatic neuroendocrine bundu (PET) rinoburitsa gastrin. Rinogona kunge riri kenza kana kuti risiri kenza.

Zvirwere zvinokonzera gastrinoma:

• Zollinger-Ellison syndrome.
• Mhando dzakawanda dzezvirwere zve endocrine neoplasia rudzi 1 (MEN1).

Mamiriro ezvinhu apo gastrin uye gastric acid zvinowedzerwa pasina gastrinomas:

• Kutadza kushanda zvakanaka kweitsvo nguva dzose.
• Kuvharika kwenzira yekubuda nayo mudumbu (GOO).

Kana gastric acid yako yakakwira, unogona kunge uine gastrin yakawanda asi gastric acid yakaderera. Izvi zvinogona kunge zvichikonzerwa ne atrophic gastritis, inova mamiriro ezvinhu apo masero anogadzira acid mudumbu anoparadzwa.

Zvikonzero zvikuru zve atrophic gastritis:

• Utachiona hweH. pylori.
• Zvirwere zve autoimmune immune (semuenzaniso autoimmune atrophic gastritis).

Zvimwe zvinokonzera kudzikira kwekugadzirwa kweasidhi mudumbu:

• Mishonga inovhara acid, yakaita seH2 blockers kana proton pump inhibitors (PPIs).
• Kuvhiyiwa kubvisa kana kuchekwa kwetsinga yeropa.

Ndingaitei kana ndine zviratidzo zvehuwandu hwemudumbu hwakakwira?

Kana uine zviratidzo zvemudumbu, kunyanya kana zvikaitika kakawanda kana kuti zvagara zviripo kwenguva yakareba, zvakakosha kuti uone chiremba. Heano mamwe ezviratidzo zvinogona kunge zvichikonzerwa nekuwedzera kwegastrin:

• Kurwadziwa kwemudumbu kana kurwadziwa kwemudumbu.
• Kurwadziwa kwechipfuva nguva dzose uye kusagadzikana kwekugaya chikafu.
• Kubuda kweasidhi mumuviri kana chikafu chichinamira pahuro.
• Kurwadziwa kunogara kuripo pahuro uye kuchema.
• Manyoka anogara achiitika.
• Matambudziko ekugaya chikafu.

Zviratidzo izvi zvinogona kuratidza kuti une acid yakawanda mudumbu, kana kuti une atrophic gastritis, peptic ulcer disease, kana GERD. Izvi zvingave zvine chekuita negastrin kana kuti kwete. Zvisinei, zvakakosha kuongorora nekurapa zvirwere izvi nemazvo.

Yeuka, kana uine zviratidzo zvakaita seizvi, usaedze kuzviongorora nekutsvaga ruzivo pa internet. Zvakanaka kuona chiremba wowana mazano.

Mharidzo Yekuenda Nayo Kumba

Zvakanaka, ngatitarisei zvimwe zvinhu zviri nyore zvekurangarira nezve gastrin yatakataura nezvayo.

• Gastrin ihormone inokosha mukugaya kwedu .
• Basa rayo guru nderekuudza dumbu kuti ribudise acid yemudumbu .
• Kana acid yemudumbu mako yakakwira zvakanyanya kana kuti yakaderera zvakanyanya , inogona kunge iine chekuita negastrin.
• Kana uine zviratidzo zvemudumbu, kana mamiriro ezvinhu asiri kuvandudzika nekurapwa, chiremba anogona kuyedza huwandu hwemudumbu mako.
• Kuwanda kwegastrin dzimwe nguva kunogona kuva chiratidzo chechirwere, saka zvakakosha kutsvaga mazano echiremba kana uine zviratidzo.

Saka, Gastrin chinhu chidiki asi chine simba chinoshanda chinyararire mumiviri yedu. Kuziva izvi kunokosha zvikuru pahutano hwako. Kana uine mimwe mibvunzo, usazeza kubvunza chiremba wako.

Gastrin , mahormone, kugaya chikafu, acid yemudumbu, maronda emudumbu, GERD, hypergastrinemia