Tinofanira kudzidza nezve H2 Blockers yekurwadziwa kwemoyo uye gastritis here?

Dzimwe nguva unonzwa kuwedzera kweasidhi mudumbu, chirungurira, kana kusagadzikana mudumbu mushure mekudya here? Kana kuti une chirwere chakadai segastritis here? Saka pamwe wakambonzwa nezvemhando yemushonga unonzi H2 blockers. Nhasi, ngatitaurei nezvemhando yemishonga iyi inonzi H2 blockers, mashandiro ayo, uye mumamiriro ezvinhu anoshandiswa.

Chii chinonzi H2 blockers (H2 antagonists)?

Zvichitaurwa zviri nyore, H2 blockers rudzi rwemushonga unoderedza huwandu hweasidhi inogadzirwa mudumbu mako. Iye zvino ungave uchishamisika kuti asidhi yemudumbu chii. Asidhi yemudumbu inokosha pakugaya chikafu chatinodya. Zvisinei, matambudziko anotanga kana asidhi iyi yakawandisa. Ipapo nyama dzakatetepa dzemudumbu medu (GI - gastrointestinal tract) dzinogona kukuvara. Ndokusaka zviratidzo zvakaita sekurwadziwa mudumbu uye chirungurira zvichiitika. Dzimwe nguva, kudya chikafu chine munyu kunogona kuoma zvekuti ungafunga kuti, "Oh, sei ndakadya izvozvo?"

Saka, kana uri munhu ane zviratidzo zvinokonzerwa nekuwedzera kweacid mudumbu, ungangoda kufunga nezvekushandisa H2 blocker.

Ndezvipi zvirwere zvinorapwa neH2 blockers?

Mishonga yeH2 blockers inonyanya kushandiswa kurapa zvirwere zvine chekuita nekuwanda kweacid mudumbu. Asi chinhu chimwe chete chekurangarira: Kana mishonga iyi ikaramba ichishandiswa, kushanda kwayo kunogona kudzikira zvishoma nezvishoma nekufamba kwenguva.

Kana uine chirwere chisingaperi uye chinogara kwenguva refu chinosanganisira acid yakawanda mudumbu, ungangoda kufunga nezvemhando yemushonga unonzi proton pump inhibitor (PPI) . Kunyange hazvo maPPI asingashande nekukurumidza semaH2 blockers, anoderedzawo kugadzirwa kweasidhi mudumbu uye anogona kushandiswa kwenguva yakareba kupfuura maH2 blockers. MaPPI imhando yemushonga une simba rekudzora acid kupfuura maH2 blockers.

Ngatitarisei mamwe ematambudziko makuru anorapwa neH2 blockers:

Maronda emudumbu uye maronda emudumbu

Kana acid yemudumbu yakakwira zvakanyanya, inogona kukanganisa dumbu uye kukonzera maronda. H2 blockers inoderedza kugadzirwa kweacid yemudumbu, zvichiita kuti maronda aya awane nguva yekupora.

Uyewo, acid yemudumbu dzimwe nguva inogona kufamba ichipinda muchikamu chekutanga chemudumbu wedu mudiki (duodenum) ichikonzera maronda ipapo. Tinodaidza kuti maronda emudumbu aya kuti duodenal ulcers . Kunyange zvazvo maPPI ari iwo mushonga unoshanda zvikuru weizvi, maH2 blockers anogonawo kurapa chirwere ichi. US Food and Drug Administration (FDA) yakabvumidza maH2 blockers ekurapa kwenguva pfupi kudzivirira maronda matsva kuti asaumbe. Chiremba wako anogona kutaura newe nezvekurapa kwakakodzera uye nzira yekuchengetedza iwe.

Acid reflux uye GERD

Iri idambudziko rine vanhu vazhinji. Kudzoka kweacid mumuviri.Zvinoreva kuti acid iri mudumbu inodzoka kumusoro, ndiko kuti, inokwira, yopinda muhuro kuburikidza nepauropu yedu (chikafu). Izvi ndizvo zvinokonzera chirungurira. Kana chirwere ichi chikaramba chiripo, kuzvimba kweuropu (esophagitis) kunogonawo kuitika. H2 blocker inogona kupa zororo kune dzimwe nguva acid reflux. Asi kana uine chirwere chenguva refu cheacid reflux, kureva GERD (Gastroesophageal Reflux Disease) , zvingave nani kushandisa PPI.

Chirwere cheZollinger-Ellison

Ichi chirwere chisingawanzoitiki. Chinoitika kana mamwe mabundu mumiviri yedu achikonzera kuti mudumbu medu mubudise acid yakawandisa. H2 blockers inogona kubatsira nekudzivisa kugadzirwa kweacid mudumbu. Zvisinei, muchiitiko ichi, chiremba wako angangokunyorera PPI.

Zviratidzo zvinoderedzwa neH2 blockers

Mishonga iyi inogona kubatsira kubvisa zviratidzo zvinotevera:

• Kuzvimba, kusagadzikana mudumbu
• Kurwadziwa kwedumbu
• Chirungurira uye kudzoka kweropa
• Kusvotwa nekurutsa
• Dumbu rinovava, kuravira kunovava pahuro

MaH2 blockers anoshanda sei?

Rimwe zita rema H2 blockers ihistamine-2 (H2) antagonists . Zita iri rinotipa pfungwa diki yekuti mishonga iyi inoshanda sei. Ungave wakadzidza nezvebasa re'antagonist' mukirasi yeChirungu pawaiva kuchikoro. Mumutsara, antagonist chimwe chinhu chinokonzera kuvharika. Nenzira imwecheteyo, H2 antagonists inovhara kugadzirwa kweasidhi yemudumbu.

Funga nezvazvo nenzira iyi. Mushure mekudya, muviri wako unoburitsa kemikari inonzi H2. H2 iyi inoenda yonamatira panzvimbo dzakatarwa (H2 receptors) pamasero ari mumadziro edumbu rako. Kubatanidzwa uku ndiko kunoita kuti dumbu rako ribudise acid.

Kana ukatora mushonga weH2 antagonist, kana kuti H2 blocker, mushonga unoenda kumaH2 receptors H2 isati yagona kuasunga. Zvichitaurwa zviri nyore, maH2 blockers "anovhara" H2 kuti isasungane nemareceptor iwayo. Izvi zvinoderedza kugadzirwa kweasidhi mudumbu.

Izvi hazvizokanganisi kugaya kwako chikafu. Asi zvinoderedza huwandu hweasidhi yakawedzerwa inokonzera zviratidzo izvozvo zvinorwadza. Wanzwisisa here?

Ndedzipi mhando dzemishonga inovhara H2? (Mishonga iripo pamusika)

Kune mhando dzakasiyana dzemishonga yeH2 blockers. Dzimwe dzaunogona kutenga kunze kwechitoro chemishonga (OTC) ku pharmacy usina kunyorerwa mushonga (Rx). Dzimwe dzinoda mushonga kubva kuna chiremba. Izvi zvinosiyana zvichienderana nerudzi rwemushonga uye chiyero chawo.

Mhando dzeH2 blockers dziripo parizvino ndeidzi:

• Cimetidine ( zita rechiratidzo, semuenzaniso, Tagamet®) - Iyi inowanikwa muOTC neRx.
• Famotidine(Zita rekambani, semuenzaniso, Pepcid®) - Izvi zvinowanikwawo muOTC neRx.
• Nizatidine (zita rechiratidzo, semuenzaniso, Axid®) - Izvi zvinongowanikwa chete neRx.

Ungave wakambonzwa nezveRanitidine ( inozivikanwa nezita rekuti Zantac®). Ndiyo yaive yekutanga H2 blocker yakatenderwa neFDA muna 1983. Zvisinei, muna Kubvumbi 2020, FDA yakaraira vagadziri kuti vabvise Ranitidine pamusika. Chikonzero cheizvi ndechekuti bvunzo dzeFDA dzakaona kuti kana Ranitidine yachengetwa kwenguva yakareba, huwandu hwekenza inogona kukonzera kenza (nitrosodimethylamine, kana NDMA) hwakawedzera kusvika padanho risina kuchengetedzeka. Vaongorori vakawanawo kuti huwandu hweNDMA hwakawedzera kana Ranitidine yachengetwa pakupisa kwakanyanya.

Mushonga uyu ungashandiswa sei?

Mishonga yakawanda yeH2 blockers inouya iri muchimiro chemapiritsi kana makapisi aunonwa nemuromo. Dzimwe nguva inouyawo muchimiro cheupfu hwaunogona kusanganisa nemvura wonwa kune vanhu vanonetseka nekumedza mapiritsi.

Mamwe maH2 blockers anogonawo kupiwa netsinga (IV) , kunyanya kana uri muchipatara uye usingakwanise kutora mushonga nemuromo.

Ndeipi nguva yakanakisisa yekutora H2 blocker?

Kana uchiziva kuti uchadya chimwe chinhu chausingade, senge chikafu chine munyu, zvakanaka kutora mushonga weH2 blocker kwemaminitsi angangoita makumi matatu kusvika makumi matanhatu usati wadya. Nenzira iyi, mushonga wacho une nguva yekutanga kushanda. Hazvina kuipa kuutora wapedza kudya, asi zvinogona kutora kusvika awa kuti zviratidzo zvako zviderere.

Sekurapa kwenguva pfupi kwechirwere chakadai seronda remudumbu, chiremba wako anogona kukuudza kuti utore mushonga uyu seizvi:

• Kamwe chete pazuva, usati warara husiku.
• Kana kamwe chete mangwanani uye kamwe chete husiku.

Chinhu chinonyanya kukosha ndechekuti kana uchida kushandisa H2 blocker kweanopfuura mavhiki maviri kuti udzore zviratidzo zvako, unofanira kuona chiremba. Hazvina kunaka kushandisa H2 blockers kwenguva yakareba usina kutaura nachiremba.

Zvinotora nguva yakareba sei kuti mishonga inovhara H2 ishande? Yakasiyana sei nemimwe mishonga?

Zvinotora inenge awa kuti unzwe kurerukirwa kubva kuzviratidzo mushure mekutora mushonga weH2 blocker. Mhedzisiro yacho inowanzogara kubva pamaawa mana kusvika gumi . Kushanda nekukurumidza uku kunoita kuti ive sarudzo yakanaka kana uchida kuzorora nekukasika kana kuti kana uchingonzwa chirungurira dzimwe nguva.

Kana uchida rubatsiro rwekukurumidza, unogona kuedza mushonga unorwisa asidhi . Mishonga inorwisa asidhi inoderedza acid iri mudumbu mako. Inotanga kushanda nekukurumidza kupfuura mushonga unodzivisa H2, asi mhedzisiro yayo haizogari kwenguva yakareba seyemushonga unodzivisa H2.

Kana zviratidzo zvako zvichigara kwenguva refu, kunyanya kana mushonga weH2 blocker usingape zororo rakakwana, ungangoda kutora PPI. PPI inogona kutora zuva rimwe kusvika mana kuti ishande zvizere, asi inogara kwenguva yakareba kupfuura mushonga weH2 blocker.

Ko ma H2 blockers ane mhedzisiro yakaipa here?

Mishonga inovhara H2 inopa zororo nenjodzi shoma yemigumisiro yakaipa. Zvisinei, semushonga upi zvawo, migumisiro midiki inogona kuitika.

Migumisiro yakajairika

• Kurwadziwa kwedumbu
• Kurwadziwa kwetsandanyama
• Kuzvimba
• Manyoka (kuzvimba kwedumbu)
• Muromo wakaoma
• Kuneta
• Musoro

Zvinhu zvekunyatsoteerera

Kunyangwe zvisingawanzoitiki, mishonga yeH2 blockers inogona kukonzera zviratidzo zvetsinga (semuenzaniso, kuvhiringidzika, kutaura zvisina kujeka) mune mamwe mapoka ane njodzi huru. Unogona kusangana nezviratidzo izvi kana uine makore anopfuura makumi mashanu uye uine kusashanda zvakanaka kweitsvo kana chiropa . Zvisinei, zviratidzo izvi zvinowanzopera mukati memazuva mashoma mushure mekumira kushandisa mushonga.

Panogona kuva nematambudziko nemimwe mishonga here?

Mamwe maH2 blockers (semuenzaniso, cimetidine) anogona kudzivirira mimwe mishonga yauri kutora kuti isashande zvakanaka. Semuenzaniso, cimetidine inogona kuderedza kushanda kwemamwe maSSRI (rudzi rwemishonga inoshandiswa kurapa zvirwere zvepfungwa zvakaita sekuora mwoyo) uye warfarin (mushonga unodzivirira kuumbwa kweropa).

Saka, usati watanga mushonga mutsva, zvakakosha kutaura nachiremba wako kuti uone kana paine kusawirirana nemishonga yauri kutotora.

Zvakachengeteka here kushandisa H2 blockers panguva yekuzvitakura nekuyamwisa?

Panodiwa tsvakurudzo yakawanda kuti paonekwe kuchengetedzeka kwekushandisa H2 blockers panguva yekuzvitakura, asi vaongorori vanoziva kuti mushonga uyu unopinda mumukaka wemuzamu .

Kana uri kutora mushonga weH2 blocker uye une mimba, iva nechokwadi chekutaura nachiremba wako. Mubvunze kana zvakachengeteka kutora mushonga uyu panguva yekuzvitakura kana panguva yekuyamwisa.

Unofanira kuona chiremba rini?

Sezvatakambotaura, kana uchifanira kushandisa H2 blockers kweanopfuura mavhiki maviri kuti udzore zviratidzo zvako, unofanira kuona chiremba. Zvakakosha kuti uzive chaizvo chiri kukonzera zviratidzo zvako. Ungangoda mushonga wenguva refu, sePPI.

Zvakare, udza chiremba wako kana uine chero kusawirirana nemishonga kana kuti ukaona chero migumisiro. Muyero wako ungada kuchinjwa kana kuti ungada kuchinja kune mumwe mushonga.

Ndeipi H2 blocker yakachengeteka? Ndeipi yakanakira GERD?

Mishonga inovhara H2 inotenderwa neFDA yakafanana zvakanyanya maererano nekuchengetedzeka kwayo uye kushanda kwayo.

Zvisinei, kana uri kutora mimwe mishonga uye uri kufunga kushandisa H2 blocker, zvakanaka kutaura nachiremba wako. Zvakakosha kusarudza mushonga usingakanganisi kushanda kwemishonga yauri kutora.

Kune GERD, chero H2 blocker inogona kubatsira kuderedza zviratidzo zveacid reflux. Zvisinei, kana acid reflux yako isingarapiki (sezvakaita GERD), zvingave nani kusiya zvachose H2 blockers wosarudza PPI. Taura nachiremba wako nezveizvi futi.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Zvakanaka, saka tataura zvakawanda nezve H2 blockers nhasi, handiti?

Mishonga inodzivisa acids yeH2, mishonga inorwisa acids, uye maPPIs ese anoshandiswa kurapa zvirwere zvinokonzerwa ne acid yakawanda mudumbu. Dzimwe nguva, nesarudzo dzakawanda kudaro, zvinogona kuvhiringidza kuziva kuti ndeipi yekusarudza.

Funga nezvazvo seizvi: Kana uchitsvaga rubatsiro rwenguva pfupi runogara kwemaawa mashoma, mishonga inovhara H2 ingave ndiyo sarudzo yakanakira iwe. Kunyanya kana uchiziva kuti ungangobatwa nechirungurira mushure mekudya chimwe chinhu chine munyu, zvakanaka kutora mushonga weH2 blocker usati watanga.

Rangarirai, kana muine mimwe mibvunzo nezvemushonga uyu, musatya kubvunza chiremba wenyu. Zvakakosha zvikuru kuziva nezvehutano hwenyu!

Mishonga inodzivisa H2 , gastritis, kuzvimba kwemudumbu, acid yemudumbu, kuzvimba kwechipfuva, maronda emudumbu, zvinyorwa zvekurapa zveSinhala