Mwana wako ari kurwadziwa nemudumbu here? Zvingave zviri chirwere cheHemolytic Uremic Syndrome (HUS)!

Mwana wako anga achirwara nemanyoka here nedumbu kwemazuva mashoma? Ungatoona ropa mariri. Zvakajairika kuti iwe, semubereki, uzvidye mwoyo zvakanyanya kana izvozvo zvikaitika. Kana uine zviratidzo zvakaita seizvi, zvinogona kunge zvinopfuura kurwadziwa kwemudumbu chete. Nhasi tichataura nezvechirwere chinogona kuva chakakomba, asi chinorapika zvikuru kana chikaonekwa nekukurumidza. Izvozvo (Hemolytic Uremic Syndrome) , kana (HUS) muchidimbu.

Chii chinonzi Hemolytic Uremic Syndrome (HUS)? Ngatizvinzwisise zviri nyore.

Zvakanaka, ngationei kuti chii ichi (HUS). Zvichitaurwa zviri nyore, idambudziko apo tsinga diki dzeropa dziri muitsvo dzedu dzinovharika . Funga nezvazvo sepombi yemvura inovharika uye mvura inomira kuyerera. Kuvharika uku kunokonzera zvinhu zvitatu zvikuru kuitika:

1. Masero ako matsvuku eropa anoparadzwa: Mukurapa, izvi zvinonzi hemolytic anemia . Masero matsvuku eropa ndiwo anotakura okisijeni mumiviri yedu yese. Saka kana aparadzwa, huwandu hweokisijeni hunodiwa nemuviri hunoderera.

2. Huwandu hwemaplatelet muropa hunoderera: Chirwere ichi chinonzi thrombocytopenia . Maplatelet masero madiki anobatsira kuti ropa redu rigwambe kana tichibuda ropa. Kana izvi zvikadzikira, zvinova zvakaoma kumisa kubuda ropa, uye mavanga anogona kuitika mumuviri wese.

3. Kukuvadzwa kweitsvo: Ichi ndicho chinhu chine njodzi zvikuru. Kana itsvo dzikasashanda zvakanaka, hadzikwanise kubvisa tsvina inoungana mumuviri. Izvi zvinonziwo (Acute Kidney Injury - AKI) .

Kunyangwe HUS ichigona kukanganisa chero munhu, inowanzo kukonzerwa nehutachiona hwebhakitiriya , kunyanya Escherichia coli , inozivikanwa seE . coli . Utachiona uhwu ndihwo hunokonzera manyoka, kunyanya manyoka ane ropa. Zvisinei, chirwere ichi muunganidzwa wezviratidzo, uye HUS inogonawo kuitika nekuda kwezvimwe zvikonzero zvisiri E. coli.

Chirwere ichi (HUS) chinogona kukanganisa kwete itsvo chete, asi dzimwe nguva dzimwe nhengo dzakadai semwoyo nehuropi. Zvisinei, chinowanzo kanganisa itsvo.

Chinonyanya kukosha: Kana iwe kana mwana wako muine manyoka ane ropa kana kuti manyoka kwemazuva anopfuura matatu, iva nechokwadi chekuona chiremba. Kana akasarapwa, HUS inogona kuva yakanyanya uye inotoisa upenyu panjodzi.

Kune mhando dzakasiyana dzeHUS here?

Ehe, kune mhando huru dzakawanda dze (HUS). Ngatidzidzei zvishoma nezvadzo:

1. "Yakajairika" (HUS): Iyi ndiyo mhando inonyanya kuwanikwa . Inowanzo kukonzerwa nehutachiona hwebhakitiriya, kunyanya E. coli, hunokanganisa ura hwedu hudiki neura.

2. "Asymptomatic" (HUS) (aHUS): Izvi hazviwanzoitiki.Izvi zvinowanzokonzerwa nezvikonzero zvemajini, zvichireva kuti zvinotorwa kubva kuvabereki kuenda kuvana.

3. "Secondary" (HUS): Rudzi urwu runoitika pamwe chete nezvimwe zvirwere. Semuenzaniso, zvinogona kukonzerwa nemishonga yakati, zvimwe hutachiona, kana pamuviri.

Ngatidzidzei zvishoma nezve "Atypical" (HUS) (aHUS)

(aHUS) chirwere chisingawanzoitiki. Chinogonawo kukonzera zviratidzo zvakafanana nechapfuura:

• Kuderera kwehuwandu hwemasero matsvuku eropa.
• Kuderera kwehuwandu hwemaplatelet.
• Kutadza kushanda kweitsvo kamwe kamwe (kutadza kushanda kweitsvo zvakanyanya) .
• Kukwira kweropa (BP) kana kutadza kudzora BP.

Chirwere ichi (aHUS) chinowanzova chirwere chemajini . Kureva kuti, chinokonzerwa nekuchinja kwakasiyana - siyana mumajini edu. Zvisinei, kunyangwe chirwere ichi chemajini chiripo, chinokonzerwa nehutachiona, chirwere, kana chimwe chinhu chiri munharaunda.

HUS (HUS) yakajairika zvakadii?

Pakati pe5% ne15% yevanhu vanobatwa nemanyoka anokonzerwa nebhakitiriya (E. coli) vanozobatwa neHUS . Rudzi rwechirwere chinonzi (aHUS) haruwanzoitiki. Runowanikwa muvanhu vanosvika mumwe chete pavanhu miriyoni imwe chete.

Ndezvipi zviratidzo zvikuru zve (HUS)?

Zvakakosha kuti uzive nezvezviratidzo izvi.

Zviratidzo zvekutanga zvinoonekwa:

• Manyoka: Anowanzo perekedzwa neropa.
• Kurwadziwa kwemudumbu.
• Kusvotwa nekurutsa.
• Musoro .
• Kutonhora nefivha.

Zvimwe zvinhu zvinoonekwa:

• Kukuvara kuri nyore.
• Ganda rakachenuruka (rakachenuruka): Mukati memhino uye kunyange mukati memuromo zvinogona kuchenuruka.
• Kuvhiringidzika.
• Kubatwa nechirwere.
• Zvirwere zvakafanana nestroke.
• Kumhanya kwemoyo nekukurumidza (arrhythmia).

Kana chirwere che (HUS) chikanyanya kuipa, masero matsvuku eropa akaparadzwa anogona kukonzera kuungana kweropa uye kukuvadza nhengo dzakadai seitsvo. Ipapo itsvo hadzigone kusefa tsvina zvakanaka. Izvi ndizvo zvatinodaidza kuti (Acute Kidney Injury - AKI) . Heano zviratidzo zvayo:

• Ropa muweti (hematuria).
• Kuwedzera kwehuwandu hwechepfu muropa: Izvi zvinogona kukonzera kusagadzikana uye kunzwa sekunge uri kurwara.
• Kukwira kweropa.
• Kutadza kufema zvakanaka (dyspnea).
• Kuzvimba: Kuzvimba kunogona kuitika, kunyanya mumakumbo nemuzviziso.
• Kuderera kwehuwandu hweweti (oliguria).

Ndezvipi zvikonzero zvikuru zve (HUS)?

Zvizhinji zvezvirwere zveHUS zvinokonzerwa nemamwe marudzi ebhakitiriya reE. coli. Mabhakitiriya aya anogadzira chepfu inonzi Shiga toxin . Chepfu iyi inokuvadza mudumbu medu uye inokonzera manyoka. Chepfu iyi inopindawo muropa, ichiparadza masero matsvuku eropa uye ichikuvadza itsvo.

Une mukana mukuru wekuwana hutachiona hweE. coli kubva:

• Nyama dzisina kubikwa zvakanaka: kunyanya nyama yemombe, nyama yakakuyiwa.
• Mukaka nezvinwiwa zvemichero zvisina kupiswa: Kupisa zvinyoro nyoro kunouraya zvinhu zvinokuvadza zvakaita semabhakitiriya.
• Michero nemiriwo zvisina kugezwa, zvakasviba.

Marudzi aya eE. coli anogadzira chepfu anonziwo Shiga toxin-producing E. coli (STEC) . Marudzi eSTEC anonyanya kuwanikwa muNorth America iE . coli O157:H7 .

Kashoma, mimwe mishonga nezvimwe zvinhu zvinogona kukonzera "secondary (HUS)". Mienzaniso:

• Mishonga yekurapa nemakemikari: yakaita se (bleomycin), (cisplatin), (gemcitabine).
• Mishonga inodzvinyirira muviri: yakaita se (cyclosporine), (tacrolimus).
• Quinine: Mushonga wemarariya.
• Mimwe mishonga : (oxymorphone), (ecstasy), (cocaine).

(HUS) inotapurirana here?

Kwete, HUS haitapurirani.

Zvisinei, mabhakitiriya eE. coli anogona kutapuriranwa. Mabhakitiriya aya anogona kutapuriranwa kuburikidza nechikafu kana zvinwiwa zvakasviba, kana nekubata tsvina yemunhu kana mhuka ine manyoka ane E. coli. Saka, zvakakosha kungwarira zvakanyanya nezvehutsanana.

Ndiani ane mukana mukuru wekuva nechirwere ichi (HUS)?

Kunyange zvazvo chero munhu achigona kuwana HUS, vanhu vanotevera vari panjodzi huru:

• Kune vana vari pasi pemakore mashanu.
• Kune avo vane masoja emuviri asina simba (asina simba rekudzivirira muviri).
• Kana mumwe munhu mumhuri mako akambova neHUS (kunyanya aHUS).
• Kana ukabatwa nechirwere cheE. coli: Kunyanya kubva pazvinhu zvakaita senyama isina kubikwa zvakanaka uye mukaka usina kupiswa.
• Kusangana zvakananga nemunhu ane manyoka anokonzerwa neE. coli.

Unoziva sei kana uine (HUS)? (Kuongororwa)

Kana ukaona chiremba, iye achaita zvinhu zvinotevera:

• Bvunza nezvenhoroondo yako yezvekurapa .
• Bvunza nezvenhoroondo yezveutano hwemhuri yako.
• Kuongororwa kwemuviri kunoitwa.

Kana zvinhu izvi zvikaita kuti pave nekufungira kuti pane chirwere cheHUS, chiremba acharaira kuti pave nekuongororwa kwakawanda.

Ndedzipi mhando dzebvunzo dzinoitwa?

• Kuongororwa kweweti: Muenzaniso weweti yako unotorwa woongororwa kana uine mapuroteni kana ropa.
• Kuongororwa kweropa: Kuongororwa kweropa kunotorwa kuti kuonekwe zvinhu zvakaita sehuwandu hwemasero matsvuku eropa, huwandu hwemaplatelet, uye kuti itsvo dzako nechiropa zviri kushanda zvakanaka sei.
• Kuongororwa kwetsvina: Sampuro yetsvina inotorwa yoongororwa kuti hapana mabhakitiriya anokonzera HUS, akadai seE. coli O157.
• Kuongororwa kwemajini: Dzimwe nguva, sampuro yeropa rako inogona kutumirwa kunoongororwa majini. Izvi zvinogona kubatsira kuona kana uine chirwere chemajini chakadai seaHUS uye kuti ndeipi mishonga yakakunakira.
• Kuongororwa kweitsvo: Izvi zvinosanganisira kutora chidimbu chidiki cheitsvo wochiongorora uchishandisa maikorosikopu kuti uone kuti itsvo dzakuvara zvakadii uye kuti chii chakakonzera izvi. Havasi vese vanoda izvi.

Kuongororwa kungaratidza sei kuti une HUS?

• Kubva pakuongororwa kweweti: Kana muweti muine ropa kana mapuroteni.
• Kuongororwa kweropa: Kana mazinga emasero matsvuku eropa nemaplatelet ari pasi, kana kana zviratidzo zvinoratidza kushanda kweitsvo (senge creatinine) zvakakwira.
• Kuongororwa kwetsvina: Kana mabhakitiriya akaita se (E. coli O157) akawanikwa.
• Kuongororwa kweitsvo: Kukuvadzwa kwakananga kweitsvo kunogona kuonekwa.

(HUS) inorapwa sei?

Kana ukaonekwa uine HUS, uchafanirwa kuenda kuchipatara uye kurapwa. Nzira dzekurapa dzinosanganisira:

• Kudyisa mwana nepamutsinga (IV) mvura uye/kana kudyisa mwana nepachubhu (kudya kunovaka muviri): Izvi zvinobatsira kudzivirira kupera mvura mumuviri uye kupa chikafu chinodiwa.
• Mishonga:
• Vanoedza kuderedza kukuvara kweitsvo nekupa mishonga inoderedza BP (mishonga inoderedza BP) .
• Vanhu vane aHUS vanogona kupihwa mishonga chaiyo yakaita seeculizumab kana ravulizumab . Usati watanga mishonga iyi, zvakakosha kuti upihwe majekiseni ekudzivirira zvirwere zvemeningococcal nepneumococcal , sezvo mishonga iyi ichiwedzera njodzi yekubata zvirwere izvozvo.
• Ungangoda kutora mishonga inorwisa mabhakitiriya kwemavhiki maviri kana kupfuura.
• Kuwedzerwa ropa: Kupa masero matsvuku eropa nemaplatelet kumunhu ane (HUS) kwakakosha zvikuru. Masero matsvuku eropa anoderedza zviratidzo zveanemia, zvakaita sekushaya mweya uye kurova kwemoyo nekukurumidza. Maplatelet anobatsira kuti ropa rigwambe zvakanaka, zvichideredza kubuda ropa uye mavanga.

Kana itsvo dzikakuvara zvakanyanya, dialysis ingangodiwa kuti ropa richeneswe kusvika itsvo dzapora. Kana itsvo dzikatadza kushanda zvachose nekuda kweHUS, itsvo inogona kudiwa kuti ibviswe .

HUS inogona kurapwa zvizere here?

Ehe, vanhu vazhinji vanopora kubva kuHUS vasina kukuvara zvachose kuhutano hwavo.

Zvisinei, vamwe vanhu, kunyanya vana vadiki, vanogona kubatwa nechirwere cheitsvo chisina kunyanya kuoma (CKD) mu20% kusvika 50%. Chirwere cheitsvo chekupedzisira (ESK) chinogona kubatwa ne3% kusvika 5%. Ongororo dzinoratidza kuti CKD inobata vanhu vakuru vanosvika 45%.

Vanhu vanopfuura 85% vanowana HUS vanopora zvizere mashandiro eitsvo dzavo. Zvisinei, kunyangwe vakapora zvachose, pane mukana mudiki wekuti vachawana BP yakakwira kana mamwe matambudziko eitsvo mune ramangwana.

HUS inogona kudzivirirwa here?

Heano zvimwe zvinhu zvaunogona kuita kudzivirira hutachiona hweE. coli, chikonzero chikuru cheHUS. Izvi zvakakosha zvikuru kwauri nemhuri yako:

• Dzivisa kushambira munzvimbo dzakasviba (madziva, nzizi), kunyanya kana uchifunga kuti mvura yacho ine mabhakitiriya akawanda.
• Kana uine manyoka, usashambire.
• Dzivisa kunwa zvinwiwa zvisina kucheneswa (zvisina kucheneswa) (mukaka, muto wemichero).
• Gara uchichenesa midziyo yemukicheni zvakanaka (mapanga, maforogo, zvipunu) nenzvimbo dzekugadzirira chikafu (makaunda, mabhodhi ekuchekera, ndiro).
• Bika mazai nenyama dzakakuyiwa zvakanaka kusvika patembiricha yemukati inosvika 71 degrees Celsius (160 degrees Fahrenheit), uye huku kusvika patembiricha yemukati inosvika 74 degrees Celsius (165 degrees Fahrenheit).
• Kana uchinyungudutsa nyama, isa mu microwave kana mufiriji. Usainyungudutsa munzvimbo yekugadzirira chikafu kana mumvura inopisa.
• Chengeta chikafu chisina kubikwa nechekare.
• Geza maoko ako nesipo nemvura inopisa usati wadya, wapedza kushandisa chimbuzi, wapedza kuchinja manapukeni evana vadiki, uye wapedza kubata zvipfuyo zvepapurazi.

Chimbofunga, nekutevera matanho aya ari nyore, unogona kuzvidzivirira kubva mumamiriro ezvinhu akaoma akadai.

Chii chaungatarisira kana uine (HUS)?

Kana vakaongororwa uye vakarapwa zvakanaka, vanhu vazhinji vane HUS vanopora zvizere vasina kukuvara zvachose kuhutano hwavo. Zvisinei, pane njodzi yekurwara neBP kana zvimwe zvirwere zvinokanganisa itsvo mune ramangwana.

Nyaya dzakakomba dzeHUS, kunyanya kana dzikakanganisa dzimwe nhengo dzemuviri, dzakadai seuropi, dzinogona kuuraya kana dzikasarapwa.

Mikana yekupona (HUS) ndeipi?

Kana vanhu vakaongororwa uye vakarapwa zvakanaka, vanhu vanopfuura 90% vanopona HUS. Saka zvakakosha kuti usatye uye usatsvage rubatsiro rwechiremba nekukurumidza kana uine zviratidzo.

Ndinozvitarisira sei?

Kana iwe kana mwana wako muine manyoka akanyanya, zvakakosha zvikuru kuedza kudzosera mvura mumuviri wenyu.Zvinwiwa zvekudzosera mvura mumuviri, zvakaita seJeevani, zvinogona kubatsira kutsiva maelectrolyte akarasika. Vacheche nevana vadiki vangangoda kupihwa mukaka wezamu kana mukaka wemushonga. Bvunza chiremba kuti ndeipi nzira yakanakisisa yekuchengetedza mwana wako aine mvura mumuviri.

Ndinofanira kuona chiremba rini?

Enda kuna chiremba nekukasika kana uine zviratidzo izvi:

• Manyoka ane ropa.
• Manyoka anogara kwemazuva anopfuura matatu.
• Kuzvimba kwemuviri.
• Ganda rinokwenya nyore.
• Kuneta kwakanyanya.

Mibvunzo ipi yandinofanira kubvunza chiremba?

Unogona kubvunza chiremba mibvunzo iyi:

• Ungazvisimbisa sei kana ndine Hemolytic Uremic Syndrome?
• Ndakawana sei Hemolytic Uremic Syndrome?
• Kana ndisina Hemolytic Uremic Syndrome, ndechipi chimwe chirwere chandingawana?
• Ndeapi marapirwo amunokurudzira?
• Itsvo dzangu dzichakuvara zvachose here?
• Ndichazotanga kuva neBP yakakwira here kana mamwe matambudziko eitsvo mune ramangwana?

Chii chinonzi triad yeHemolytic Uremic Syndrome?

Triad musanganiswa wezviratidzo zvikuru zvitatu zvinoratidza chirwere chakati.

Hemolytic Uremic Syndrome triad inosanganisira:

1. Kukuvadzwa kwemasero matsvuku eropa (microangiopathic hemolytic anemia) .

2. Kudzikira zvishoma nezvishoma kwehuwandu hwemaplatelet muropa rako (thrombocytopenia) .

3. Kukuvara kwakanyanya kweitsvo.

Kana ndiine manyoka, zvinoreva here kuti ndine Hemolytic Uremic Syndrome?

Kungoti une manyoka hazvirevi kuti une Hemolytic Uremic Syndrome. Zvisinei, kana uine manyoka ane ropa, kana kuti manyoka ako akanyanya (kusvika pakubuda manyoka ane mvura yakawanda kana kuti anogara kwemazuva anopfuura matatu), unofanira kuona chiremba.

Ndeupi musiyano uripo pakati pe (Hemolytic Uremic Syndrome) ne (Thrombotic Thrombocytopenic Purpura - TTP)?

Hemolytic Uremic Syndrome (HUS) neThrombotic Thrombocytopenic Purpura (TTP) zvirwere zviviri zvakafanana. MuTTP, ropa rinogwamba mutsinga diki dzeropa. Kunyangwe vanachiremba vaimbobatanidza HUS neTTP pamwe chete, ikozvino zvinoonekwa sezvirwere zvakasiyana.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Manyoka anowanzova mamiriro enguva pfupi, asi asingafadzi. Anowanzova nani muzuva rimwe kana maviri. Zvisinei, kana uine manyoka ane ropa, kana kuti uine manyoka kwemazuva anopfuura matatu, pamwe chete nekuneta, kucheneruka, kana kuita weti shoma paunoenda kuchimbuzi, inguva yekuona chiremba nekukasika.

Chirwere chinonzi Hemolytic Uremic Syndrome chinogona kukuvadza itsvo dzako zvakanyanya uye kukanganisa dzimwe nhengo dzemuviri.Kana ukangokurumidza kurapwa izvi, mikana yako yekukuvara kweitsvo kwenguva refu hainyanyi kukura. Saka, ziva zviratidzo, chengetedza hutsanana hwakanaka, uye tsvaga mazano echiremba kana uine zvinokunetsa. Hutano hwako hwakakosha zvikuru kwauri!

` Hemolytic Uremic Syndrome, HUS, Chirwere cheItsvo, Manyoka, E. coli, Masero Matsvuku eRopa, Maplatelet, Hutano hweVana