Mahormone akafanana nenhume diki dzinobatanidza mabasa akasiyana-siyana mumuviri wedu. Fungidzira, mahormone aya anowedzerwa muropa redu negland riri mumuviri wedu. Zvadaro, mahormone aya anofamba nemuropa opa mashoko kunhengo yega yega, akadai sekuti "ita izvi" uye "rega izvi". Kutaura zvazviri, muviri wedu haugone kushanda zvakanaka pasina mahormone. Asi dzimwe nguva, nhume idzi dzakanaka dzinobatsirawo mamwe masero ekenza "kukura zvakanaka nekukasira". Ndipo panotanga kukosha kurapwa nemahormone kwatiri.
Saka kurapwa kwemahormone uku kunoshanda sei?
Zvichitaurwa zviri nyore, kurapwa kwemahormone kunoshanda nekudzivirira nzira iyo masero ekenza anowana mahormone aanoda kuti akure. Izvi zvinogona kuitwa nenzira dzakasiyana-siyana. Chiremba wako ndiye achasarudza nzira yekushandisa zvichienderana nemamiriro ako ezvinhu.
- Kumisa kugadzirwa kwemahormone: Mamwe masero ekenza anokwanisa kumira kugadzira mahormone anoabatsira kukura. Mune zvimwe zviitiko, mahormone anogadzira mahormone aya angatoda kubviswa nekuvhiyiwa.
- Kuvhara mashandiro emahormone: Munzira iyi, kunyangwe muviri uchigadzira mahormone, masero ekenza anodziviswa 'kushandisa' mahormone iwayo. Funga nezvesero rekenza seimba, uye hormone sekiyi. Kurapa uku kwakafanana nekuvhara gomba rekiyi rinokodzera kiyi. Zvadaro, kunyangwe kiyi iripo, musuwo haugone kuvhurwa.
- Kurapa kwekuchinja mahormone: Dzimwe nguva, panzvimbo pemahormone echisikigo ari mumiviri yedu, tinopa miviri yedu mhando yehormone yakagadzirwa murabhoritari (Bioidentical hormones). Mahormone aya ekugadzira haagone kushandiswa nemasero ekenza kuti akure. Nemamwe mashoko, panzvimbo pehormone inodiwa nemasero ekenza, anoapa hormone 'yenhema' yaasingakwanise kushandisa, asi inotaridzika zvakafanana.
Chinhu chakakosha ndechekuti kurapwa nemahormone kushande nekubvisa mafuta anowanikwa mumasero ekenza. Izvi zvinogona kuitwa wega kana pamwe chete nedzimwe nzira dzekurapa dzakadai sekuvhiyiwa, chemotherapy, kana radiation therapy.
Mushonga uyu unoshandiswa pamhando dzipi dzegomarara?
Kurapa nehomoni hakushandiswi pamhando dzese dzegomarara. Kunonyanya kushandiswa pagomarara rinoenderana nemahomoni. Mamwe acho anosanganisira:
- Kenza yeprostate
- Kenza yemazamu
- Kenza yeOvarian
- Kenza yechibereko
Ngationei kuti kurapwa nemahormone kunokanganisa sei mhando dzegomarara idzi zvakasiyana.
Kurapa nehomoni yekenza yeprostate
Masero ekenza yeprostate anowanzoda mahormone echirume, kunyanya testosterone, kuti akure. Saka chinangwa chikuru chekurapa uku ndechekuderedza huwandu hwemahormone aya kana kuamisa kushanda. Mune zvimwe zviitiko, kubviswa kwechende rimwe chete kana ese ari maviri, ayo anogadzira testosterone, (orchiectomy) kunotoitwa sechikamu chekurapa uku.
Kana mishonga ikashandiswa, mishonga inotevera inogona kushandiswa zvakanyanya.
| Rudzi rwemushonga | Mashandiro azvinoita |
|---|---|
| Abiraterone acetate | Mushonga uyu unomisa kugadzirwa kwemahormone echirume (androgens) mukati memasero ekenza yeprostate. Unowanzo kunyorerwa varume vasingapindure kune mamwe marapirwo emahormone. |
| Mishonga yeLHRH agonists | Mishonga iyi inozivisa gland repituitary riri muuropi hwedu kuti rirege kuburitsa hormone inoudza machende kuti agadzire testosterone. Saka, kana testosterone yamira, masero ekenza anomira kukura. |
| Mishonga inorwisa androgens | Izvi zvinoshanda nekudzivirira testosterone inogadzirwa mumuviri kuti isasungane nemasero ekenza. Izvi zvinoreva kuti kunyangwe kana hormone iripo, sero rekenza harigone kubatsirwa nayo. |
Migumisiro inogona kuitika
Mimwe migumisiro inogona kuitika kana uchitora mushonga uyu. Zvisinei, izvi hazviitike kune wese munhu uye vamwe vanhu vangasasangana nemhedzisiro. Zvakanaka kutaura nachiremba wako nezveizvi.
- Kuwedzera uremu.
- Kuderera kana kurasikirwa nechido chebonde.
- Kusashanda zvakanaka kwenhengo dzesikarudzi.
- Kuderera kwehuwandu hwemapfupa (Osteoporosis).
Kurapa nehomoni yekenza yemazamu
Makondombera emazamu anosvika masere pagumi anoenderana nemahormone. Zvichitaurwa zviri nyore, estrogen, hormone yechikadzi, inobatsira masero ekenza aya kukura. Funga nezvemasero ekenza seane 'antenna' shoma pamusoro pawo anogona kubatana nemahormone. Tinodaidza aya mahormone receptors. Kana estrogen yakabatana nemaantenna aya, sero rekenza rinogamuchira chiratidzo chekukura. Tinodaidza aya makenza e'hormone receptor-positive' .
Kurapa nehomoni kunoshanda nekuderedza huwandu hweestrogen mumuviri kana kudzivirira hormone estrogen kuti isasungane nemasero ekenza. Kurapa uku kunowanzoitwa mushure mekuvhiyiwa kuderedza njodzi yekuti kenza idzoke zvakare.
| Rudzi rwemushonga | Mashandiro azvinoita |
|---|---|
| Zvinodzivisa Aromatase | Mishonga iyi inoderedza huwandu hweestrogen mumuviri nekuvharira enzyme inonzi aromatase, iyo inoshandura mamwe mahormone kuita estrogen. Inowanzopihwa vakadzi vakambosvika panguva yekuguma kwemwedzi. |
| MaSERM (Selective estrogen receptor modulators) | Mishonga iyi inodzivirira hormone inonzi estrogen kuti isasungane nema receptors ari pamasero ekenza yemazamu, saka masero ekenza haagamuchire chiratidzo chekuti akure. |
| ERDs (Estrogen receptor down controllers) (Zvinodzora estrogen receptor pasi) | Izvi zvinovhara kushanda kweestrogen uye zvinoderedza huwandu hweestrogen receptors pamasero ekenza, zvichiita kuti asakwanise kubatana neestrogen. |
Migumisiro inogona kuitika
- Kurwadziwa kana kuomarara kwemajoini.
- Kuneta.
- Kusvotwa nekurutsa.
- Kuwedzera uremu.
- Kuderera kwechido chepabonde.
- Kupisa kunopisa.
- Kurwadziwa kwezamu kana kuzvimba.
Kurapa mahormone ekenza yemazamu nekenza yechibereko
Kurapa nemahormone kunoshandiswa kune dzimwe mhando dzisingawanzoitiki dzekenza yemuchibereko nekenza yemuchibereko. Mukenza yemuchibereko, mushonga unonzi progestin, unoshanda sehormone progesterone, unonyanya kushandiswa. Izvi zvinononotsa kukura kwemasero ekenza.
Mishonga yakaita seLHRH agonists, tamoxifen, uye aromatase inhibitors inogona kushandiswawo kurapa mhando dzese dzegomarara.
Migumisiro inogona kuitika
- Kupisa kunopisa.
- Kuoma kwechikadzi.
- Kuderera kwehuwandu hwemapfupa (Osteoporosis).
- Kurwadziwa kwemajoini netsandanyama.
- Kuwedzera uremu.
- Kudikitira husiku.
Ndedzipi nzira dzekurapa nenjodzi dzacho?
Kurapa nemahormone kunopiwa nenzira mbiri huru. Imwe ndeyekunwa mapiritsi kana makapisi nemuromo (mishonga inonwiwa) . Imwe ndeyekubaya jekiseni . Nzira iyi inosiyana zvichienderana nerudzi rwekurapwa kwawakapihwa.
Kufanana nechero kurapwa kwegomarara, kurapwa nemahormone kune njodzi yemigumisiro yakaipa. Zvisinei, izvi zvinosiyana zvikuru kubva kumunhu kusvika kumunhu. Zvinhu zvakawanda zvinokanganisa izvi, kusanganisira hutano hwako hwese uye rudzi rwekurapwa nemahormone kwaunowana.
Chinhu chinonyanya kukosha ndechekutaura pachena nachiremba wako nezvemigumisiro inogona kuitika uye maitiro ekuzvidzora usati watanga kurapwa. Iye achakutsanangurira zvese.
Ndezvipi zvakanakira uye mwero wekubudirira kwekurapwa kwemahormone?
Kubatsira kukuru kwekurapa nehomoni ndekwekuti kunobatsira kumisa kana kuderedza kukura kwegomarara. Kunoshanda zvakanyanya kana kukashandiswa pamwe chete nedzimwe nzira dzekurapa. Dzimwe nguva, kunogona kushandiswa kuderedza bundu risati ravhiyiwa uye kudzivirira gomarara kuti risadzoke mushure mekuvhiyiwa.
Zvakaoma kutaura kuti kurapa uku kunoshanda sei chaizvo. Zvinoenderana nezvinhu zvakawanda, kusanganisira rudzi rwegomarara raunaro, kuti rapararira zvakadii, zera rako, uye hutano hwako hwese. Ruzivo rwakanakisisa nezvechirwere chako runogona kuwanikwa chete kuna chiremba wako ari kurapa. Saka usatya kumubvunza nezvazvo.
Kana uri kugamuchira kurapwa kwemahormone, zvakakosha zvikuru kuenda kumakiriniki uye kuongororwa nenguva sezvakarairwa nachiremba wako.
Mharidzo Yekuenda Nayo Kumba
- Mahormone inhengo dzemakemikari dzinodzora mabasa akasiyana-siyana mumuviri wedu.
- Mamwe marudzi egomarara, akadai seprostate nezamu, anoenderana nemahormone kuti akure.
- Kurapa nemahormone kunoshanda nekubvisa mahormone anodiwa nemasero ekenza kana kudzivirira mashandiro awo.
- Kurapa uku kunopihwa semapiritsi kana majekiseni.
- Migumisiro inogona kuitika, asi inosiyana kubva kumunhu kuenda kumunhu uye inogona kugadziriswa.
- Zvakakosha zvikuru kutaura pachena nachiremba wako nezvemibvunzo kana zvinokunetsa.
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