Kana mumwe munhu mumhuri yako, pamwe amai vako vaunoda, baba, ambuya kana tete, vari kurwara nechirwere cheAlzheimer, tinoziva kuti zvinogona kuoma sei. Mashoko haagone kutsanangura kusuruvara uye kushaya simba kwaunonzwa sezvaunorasikirwa nendangariro dzako zvishoma nezvishoma uye zvichikuomera kuita mabasa ezuva nezuva. Kunyangwe hazvo pasina mushonga wechirwere cheAlzheimer, kune mishonga inogona kubatsira kudzora zviratidzo uye kuita kuti hupenyu huve nyore. Saka, nhasi tiri kutaura nezvekirasi yakakosha yemishonga inowanzo kurudzirwa navanachiremba pakuita izvi.
Ngatingonzwisisai kuti mushonga uyu unoshanda sei, handiti?
Kuti tinzwisise izvi, ngatitangei tatarisa mashandiro anoita pfungwa dzedu. Masero etsinga ari muuropi hwedu, anonzi ma neuron, anotaura pamwe chete uye anochinjana ruzivo kuburikidza nevatumwa vemakemikari, sezvinoita munhu anotakura tsamba.
Imwe yenhume dzakakosha iacetylcholine . Inobatsira nezvinhu zvakawanda zvakakosha zvakaita sekurangarira kwedu, kudzidza, uye kutarisisa.
Zvisinei, kana chirwere cheAlzheimer chikatanga, masero etsinga anogadzira nhume idzi anonzi acetylcholine anoparadzwa zvishoma nezvishoma. Ipapo huwandu hwenhume idzi muuropi hunoderera. Dzinosara dzinoparara zvechisikigo kana dzapedza basa radzo.
Apa ndipo panopinda mishonga inonzi Cholinesterase Inhibitors . Mishonga iyi inoshanda nekunonotsa kuputsika kweasara acetylcholine messengers. Izvi zvinoreva kuti inochengetwa uye inobvumirwa kushanda muuropi kwenguva yakareba sezvinobvira. Izvi zvinoguma nekuvandudzika kwechinguva mundangariro nehunyanzvi hwekufunga.
Zvichitaurwa zviri nyore, mishonga iyi hairapi chirwere. Asi, inodzora zviratidzo uye inopa murwere zororo kwenguva pfupi.
Mishonga inowanzoshandiswa yeCholinesterase Inhibitors
Kune mishonga yakawanda yeCholinesterase Inhibitor inotenderwa kurapa chirwere cheAlzheimer pasi rose nemuSri Lanka. Chiremba wako achasarudza mushonga wakakodzera zvichienderana nerudzi rwechirwere uye mamiriro emurwere.
| Zita remushonga (zita rechiratidzo) | Makesi ekushandisa | Migumisiro yakajairika |
|---|---|---|
| Donepezil (Aricept) | Kune varwere vane chirwere chisina kunyanya kuoma, chiri pakati nepakati, uye chakakomba. Inotorwa piritsi rimwe chete kamwe chete pazuva. | Kusvotwa, kurutsa, kuzvimba kwechiropa, kurwadziwa kwetsandanyama, kuneta, kushaya chido chekudya. |
| Rivastigmine (Exelon) | Kune varwere vane ganda rakapfava kusvika riri pakati nepakati (mapiritsi). Inowanikwawo sechigamba cheganda kune varwere vane ganda rakakomba. | Kusvotwa, kurutsa, kuzvimba kwechiropa, kurasikirwa nechido chekudya, uye kurwadziwa mudumbu (izvi hazviwanzoitiki kana uchishandisa chigamba). |
| Galantamine (Razadyne) | Kune varwere vane chirwere ichi vari pakati nepakati, tora kaviri pazuva kana sekapuleti inoshanda kwenguva refu kamwe chete pazuva. | Kusvotwa, kurutsa, kuzvimba kwechiropa, kushaya chido chekudya, musoro , dzungu. |
| Donepezil + Memantine (Namzaric) | Inogadzirwa pamwe chete nemumwe mushonga (NMDA agonist) kune varwere vane chirwere ichi vari pakati nepakati kusvika pakanyanya. | Musoro , kuvhiringidzika, dzungu, kuvimbiwa, kuda kurutsa, kurutsa. |
Ko kana ndikava nemigumisiro yakaipa pandinotanga kutora mushonga?
Vamwe vanhu vanogona kusangana nematambudziko pavanotanga kutora mushonga uyu. Asi musazvidya mwoyo. Kazhinji, matambudziko aya anozopera kana muviri wenyu wajaira mushonga wacho. Chiremba wenyu anowanzotanga nemipimo yakaderera uye anowedzera mushonga zvishoma nezvishoma.
Kana uine kuda kurutsa, kutora mushonga pamwe chete nechikafu kunogona kubatsira kudzora dambudziko racho. Chinhu chakakosha kutaura nachiremba wako nezve chero kusagadzikana kwauri kusangana nako. Iye ndiye achakwanisa kukupa mhinduro yakanakisisa.
Mushonga uyu unoshanda zvakadini zvechokwadi?
Iri idambudziko revanhu vazhinji. Kutaura chokwadi, mhedzisiro yemishonga iyi ndeyenguva pfupi. Vamwe varwere vanogona kuona kudzikira kukuru kwezviratidzo. Vanokwanisa kufunga zvakajeka, kurangarira zvinhu, uye kuita mabasa ezuva nezuva zviri nyore. Dambudziko iri rinogona kugara kwemakore akati wandei.
Asi tinofanira kunzwisisa kuti izvi zvakafanana nekuisa plaster kwenguva pfupi pamusoro petangi rinodonhedza mvura. Zvinoita kuti mvura isadonhedze kwenguva yakati, asi chigamba chacho hachizoshandi sezvo gomba riri mutangi richikura. Saizvozvowo, mishonga iyi haigone kumisa kana kugadzirisa kukuvara kweuropi kunokonzerwa nechirwere cheAlzheimer. Nekufamba kwenguva, sezvo chirwere ichi chichienderera mberi, uye kugadzirwa kweacetylcholine muuropi kunenge kwamira zvachose, mishonga iyi hainawo simba.
Pane vanhu vasingafaniri kutora mushonga uyu here?
Ehe. Mushonga uyu haukodzeri munhu wese. Mishonga inodzivirira cholinesterase inogona kuderedza kurova kwemoyo neBP. Saka, vanachiremba vanongwarira zvikuru pavanoupa kuvanhu vane mamwe matambudziko ehutano.
- Vanhu vane asthma
- Vanhu vane kutadza kushanda zvakanaka kwemoyo
- Vanhu vane chirwere cheitsvo kana chechiropa
- Vanhu vane maronda emudumbu
Kana mudiwa wako aine chimwe chezvirwere izvi, iva nechokwadi chekuzivisa chiremba wako nezvazvo.
Zvakakosha: Udza chiremba wako nezvemishonga , mavhitamini, zvekudya zvinovaka muviri, uye kunyange mishonga yeAyurvedic kana yeSinhala iri kutorwa newaunoda. Mimwe mishonga (semuenzaniso, mimwe mishonga yedzihwa uye yekurwara) inogona kushanda pamwe chete neiyi Cholinesterase Inhibitors, zvichiita kuti mishonga yese isashande zvakanaka kana kukonzera migumisiro yakaipa.
Mharidzo Yekuenda Nayo Kumba
- Mishonga inodzivirira cholinesterase haisi mushonga wechirwere cheAlzheimer. Inongodzora kwenguva pfupi zviratidzo zvine chekuita nekuyeuka nekufunga.
- Mushonga uyu unoshanda nekuwedzera huwandu hwemakemikari anonzi acetylcholine muuropi.
- Migumisiro yakadai sekusvotwa nekurutsa inogona kuitika pakutanga kwemushonga, asi inowanzo derera nekufamba kwenguva.
- Usamborega kutora mishonga kana kuchinja mwero wemushonga usina kurairwa nachiremba wako.
- Zvakakosha kuzivisa chiremba wako nezvemimwe mishonga yese iri kutorwa newaunoda.
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