Unowanzonzwa usina simba uye mapfupa ako achirwadza here? Kana kuti chiremba wako akaongorora mushumo weropa ndokuti, "Calcium yako yakakwira zvishoma"? Pamwe chikonzero cheizvi chirwere chatisingataure zvakawanda nezvacho, asi chakakosha zvikuru. Nhasi, ngatitaurei nezvechirwere ichi chinonzi hyperparathyroidism nenzira iri nyore yaunogona kunzwisisa.
Chii chinonzi hyperparathyroidism?
Zvichitaurwa zviri nyore, hyperparathyroidism inoitika kana rimwe kana akawanda emagland ako eparathyroid akashanda zvakanyanya uye achigadzira parathyroid hormone (PTH) yakawandisa. Izvi zvinokonzera kuti calcium muropa rako ikwire. Mukurapa tinoti izvi hypercalcemia .
Fungidzira, kuseri kwegland re thyroid mumutsipa wedu, kune gland ina diki dzine saizi yemupunga. Idzi dzinonzi parathyroid glands. Kungofanana nebhora rinodzora huwandu hwemvura mutangi redu remvura kumba, basa guru regland idzi nderekudzora huwandu hwecalcium ne phosphate muropa redu pahuwandu hwakakodzera.
Aya ndiwo mashandiro azvinoita:
- Kana huwandu hwecalcium muropa hukadzikira, magland aya anogadzira hormone inonzi PTH.
- Homoni iyi yePTH inotumira chiratidzo kumapfupa edu kuti "abudise calcium muropa."
- Inoudzawo itsvo kuti "dzikise huwandu hwecalcium inobuda muweti uye irambe iri mumuviri."
- Zvadaro, itsvo dzinoita kuti vhitamini D ishande uye dzinoitumira muura hwedu . Zvadaro, ura hunotora calcium iri muchikafu chatinodya zvakanaka.
Iyi inzira yakaringana zvikuru. Zvisinei, mu hyperparathyroidism, hormone yePTH inogadzirwa yakawandisa, zvichiita kuti mapfupa arambe achiburitsa calcium, zvichiita kuti ave matete uye atetepe. Pamusoro pezvo, calcium yakawandisa inoungana muropa inogona kuiswa muitsvo (inogona kuumba matombo), mitsipa yeropa, mwoyo, nedzimwe nhengo dzemuviri, zvichikonzera matambudziko akasiyana-siyana ehutano.
Ndeapi marudzi makuru echirwere ichi?
Hyperparathyroidism inogona kukamurwa kuita mhando nhatu huru, idzo dzinorongwa zvichienderana nekuti dzinoitika sei.
| Rudzi | Zvichitaurwa zviri nyore... |
|---|---|
| Hyperparathyroidism yekutanga | Dambudziko riripo panyaya iyi ndere parathyroid gland pachayo. Bundu (rinowanzova rekenza) mugland kana kukura kwegland kunoita kuti muviri ugadzire PTH hormone kunyangwe usingaidi. |
| Hyperparathyroidism yechipiri | Haisi mhosva yemagland pano. Chimwe chirwere (chinowanzova Chronic Kidney Disease) chinoita kuti huwandu hwecalcium mumuviri hudzike. Zvichitevera izvi, magland eparathyroid anotanga kushanda kwenguva yakareba kuti atsive kushomeka kwecalcium mumuviri. |
| Hyperparathyroidism yepamusoro | Izvi zvinoitika kana chirwere chechipiri chisina kurapwa kwenguva yakareba. Matumbu anoramba achishanda nesimba, achikura uye achigadzira hormone yePTH isingadzoreki. |
Zviratidzo zvacho ndezvipi?
Vanhu vazhinji vane chirwere ichi havana zviratidzo . Kuwanda kwecalcium muropa kunowanzoonekwa netsaona panguva yekuongororwa kweropa nekuda kwechimwe chikonzero. Zvisinei, vamwe vanhu, kunyanya kana calcium yavo yakakwira zvakanyanya, vanogona kusangana nezviratidzo zvinotevera:
- Kurwadziwa kwemapfupa nemajoini
- Kushaya simba kwetsandanyama
- Kuneta nguva dzose uye kuneta
- Kuora mwoyo
- Kuomerwa nekutarisa pane chimwe chinhu
- Kuda kudya
- Kusvotwa nekurutsa
- Kuvhiringidzika, kukanganwa zvinhu
- Kunzwa nyota yakanyanya uye kuda kuita weti kakawanda
- Kuzvimba
Yeuka kuti zviratidzo izvi zvinowanzoitika. Havasi vese vane zviratidzo izvi vane hyperparathyroidism. Asi kana zviratidzo izvi zvikaramba zviripo, zvakanaka kuti uone chiremba.
Chii chinokonzera izvi?
Ngatitarisei zvikonzero zvemarudzi matatu atakurukura kare zvakasiyana.
Zvinokonzera Hyperparathyroidism Yekutanga
- Adenoma: Iri bundu risiri rekenza rinoumbwa muparathyroid gland. Ichi ndicho chikonzero chinowanzoita kuti pave neprimary hyperparathyroidism.
- Hyperplasia: Apa ndipo apo imwe ye parathyroid glands inokura.
- Kenza:Kenza yemagland eparathyroid idambudziko risingawanzoitiki .
Zvinokonzera Hyperparathyroidism Yechipiri
Chikonzero chikuru cheizvi iChronic Kidney Disease (CKD) . Kana itsvo dzisiri kushanda zvakanaka, huwandu hwephosphate mumuviri hunowedzera uye huwandu hwevhitamini D hunoderera. Izvi zvinoita kuti huwandu hwecalcium muropa huderere. Saka, kuti zvikwanisike kushaikwa kwecalcium uku, parathyroid glands inoburitsa PTH hormone yakawandisa.
Uyezve, kushomeka kwakanyanya kwevhitamini D (nekuda kwekushaya zuva kana kushomeka kwekudya kunovaka muviri) kunogonawo kukonzera izvi.
Ungaziva sei chirwere ichi?
Chiremba wako achateerera zviratidzo zvako, okuongorora, uye okutumira kune dzimwe bvunzo kana vachifungidzira kuti une chirwere ichi.
| Bvunzo | Uri kuonei? |
|---|---|
| Kuongororwa kweRopa | Kuwanda kwecalcium muropa, PTH hormone, vhitamini D, phosphate, uye mashandiro eitsvo (Creatinine) zvinoongororwa. |
| Kuedzwa kweWeti kwemaawa makumi maviri nemana | Huwandu hwecalcium muweti hunounganidzwa mukati memaawa makumi maviri nemana hunoyerwa. |
| Kuskena Parathyroid | Izvi zvinogona kubatsira kuona kuti ndeipi gland iri kushanda zvakanyanya. Izvi zvakakosha zvikuru usati wavhiyiwa. |
| Kuskena kweUltrasound | Inoshandiswa kutarisa mamiriro egland neitsvo mumutsipa. |
| Kuongororwa Kwekuwanda Kwemapfupa | Kuongororwa uku kunoitwa kuti kuonekwe kana mapfupa arasikirwa necalcium uye apera simba (Osteoporosis). |
Inorapwa sei?
Nzira dzekurapa dzinoenderana nekuti une rudzi rwekutanga here kana kuti rwechipiri uye kuti chirwere chacho chakakomba zvakadini.
Kurapa kweprimary hyperparathyroidism
Mhinduro yakanakisisa uye inogara iripo yeizvi ndeyekuvhiya (parathyroidectomy) kubvisa gland kana magland anonyanya kushanda. Mushure mekuvhiya uku, vanhu vanopfuura 90% vanodzokera padanho recalcium muropa.
Kana uri pasi pemakore makumi mashanu, uine zviratidzo, uine calcium yakawanda, uine matombo muitsvo, kana uine mapfupa matete, chiremba wako achakurudzira kuvhiyiwa.
Muzviitiko zvisiri zvakakomba uye zvisingade kuvhiyiwa, chiremba wako achagara achitarisa mamiriro ako ezvinhu. Anogona zvakare:
- Bisphosphonates: Mishonga iyi inodzivirira kuburitswa kwecalcium mumapfupa uye inoasimbisa.
- Calcimimetics: Mishonga iyi "inonyengera" magland eparathyroid kuti aderedze kugadzirwa kwehomoni yePTH.
- Kuchinja mararamiro: Unogona kukurudzirwa kurega kushandisa mimwe mishonga (semuenzaniso, thiazide diuretics, lithium) uye kuchinja zvekudya.
Kurapa kwe hyperparathyroidism yechipiri
Chinokosha apa ndechekurapa chinokonzera chirwere ichi , zvakaita sekudzora chirwere cheitsvo uye kurapa kushomeka kwevhitamini D.
- Munhu ane chirwere cheitsvo angada dialysis kana kuisirwa itsvo.
- Mishonga yakaita se phosphate binders inopiwa kuderedza huwandu hwe phosphate muropa.
- Vitamini D nemishonga ye calcimetic inoshandiswawo pachinangwa ichi.
Kana kurapwa uku kusingakwanise kudzora mamiriro acho ezvinhu, kuvhiyiwa kunogona kudiwa.
Chinonyanya kukosha ndechekuti, usangotora mapiritsi evhitamini D kana calcium wega. Gara uchibvunza chiremba wako uye shandisa mapiritsi aya chete sezvawakarairwa. Dzimwe nguva izvi zvinogona kuita kuti zvinhu zvinyanye kuipa.
Mharidzo Yekuenda Nayo Kumba
- Hyperparathyroidism chirwere chinokonzerwa nekuwedzera kwecalcium muropa nekuda kwekugadzirwa kwakanyanya kwehomoni yePTH neparathyroid glands.
- Kazhinji, hapana zviratidzo chaizvo. Unogona kusangana nezviratidzo zvakaita sekuneta uye kurwadziwa kwemapfupa.
- Rudzi rwekutanga runokonzerwa nedambudziko riri mugland pacharo, nepo chikonzero chikuru cherudzi rwechipiri chiri chirwere cheitsvo chisingaperi.
- Chirwere ichi chinoonekwa kuburikidza neropa, kuongororwa kweweti, uye kuskena.
- Kurapa kwakanakisa kwerudzi rwekutanga kubvisa gland rakakanganiswa nekuvhiyiwa.
- Gara uchibvunza chiremba wako usati washandisa chero mushonga kana vhitamini.
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