Utachiona hweC. diff (Clostridioides difficile): Ngatizivei kuti kurwadziwa kwemudumbu uku kunokonzerwa nei.

Dzimwe nguva unomborwadziwa nemudumbu kana manyoka zvinogara kwemazuva mashoma here? Tinowanzo funga kuti, 'Aa, chikafu ichi chinofanira kunge chaive chine chepfu zvishoma' kana kuti 'Inofanira kunge iri furuwenza yehutachiona.' Asi dzimwe nguva zviratidzo izvi zvinogona kukonzerwa nehutachiona hwakakomba hunogona kukuvadza ura hwedu. Humwe hwehutachiona hwakadaro ndiC. diff (Clostridioides difficile).

Chii chinonzi C. diff (Clostridioides difficile)?

Zvichitaurwa zviri nyore, C. diff rudzi rwebhakitiriya. Zita chairo ndi `(Clostridioides difficile)`. Bhakitiriya iri rinogona kukonzera hutachiona muura hwako hukuru, kureva `(colon)`. Ndipo panotanga zviratidzo zvisingafadzi zvakaita semanyoka. Zvino, ngationei, zvakajairika kuti ura hwedu hukuru huwane hutachiona hwebhakitiriya. Huwandu hwacho hahuna kunyanya kuipa. Asi hutachiona hweC. diff uhwu hwakanyanya kuipa. Chikonzero ndechekuti bhakitiriya iyi `(Clostridioides difficile)` inoburitsa chepfu. Chepfu idzi dzinokuvadza masero ari mukati meura hwedu. Izvi zvinokonzera kuzvimba kwemukati meura neura hukuru, kureva, kuzvimba (colitis). Kana ukava nezviratidzo uye kuti zvakakomba sei zvinoenderana nehukuru hwekukuvadzwa kunokonzerwa nehupfu uhwu. Dzimwe nguva chirwere ichi chinogona kutotyisidzira hupenyu. Bhakitiriya iyi yaimbonzi `(Clostridium difficile)`. Iye zvino zita idzva ndi `(Clostridioides difficile)`.

Utachiona hweC. diff hwakajairika zvakadii?

Chirwere cheC. diff, kana kuti CDI, idambudziko rehutano pasi rose. Zvisinei, hapana nhamba chaiyo yekuti chakapararira sei pasi rose. MuUnited States, zvinofungidzirwa kuti kune vanhu vanosvika 500,000 vanobatwa nechirwere ichi pagore, uye vanhu vanosvika 15,000 vanofa. Saka ichi hachisi chinhu chekurerutsa.

Ndezvipi zviratidzo zvehutachiona hweC. diff?

Chiratidzo chekutanga uye chinowanzoonekwa manyoka ane mvura. Muzviitiko zvisina kusimba, manyoka anoitika katatu pazuva, uye panogona kuva nekurwadziwa mudumbu. Sezvo hutachiona hweC. diff huchienderera mberi, kuwanda kwemanyoka kunowedzera. Anogona kuitika kusvika ka10-15 pazuva. Unogonawo kuona ropa mutsvina yako. Zvimwe zviratidzo zvinosanganisira:

• Kuva nekurwadziwa kwemudumbu nguva dzose
• Dumbu razara uye rakazvimba.
• Kusvotwa nekurutsa
• Kuda kudya
• Kupindwa nechando
• Kuwedzera kwekurova kwemoyo

Pakutanga, zviratidzo zveC. diff zvinogona kunge zvakaita sechepfu yechikafu kana furuu yemudumbu. Kana uri kutora mishonga inorwisa mabhakitiriya, unogona kufunga kuti manyoka acho anokonzerwa nemishonga.

Asi yeuka, dzimwe nguva hutachiona hweC. diff hunogona kuitika pasina manyoka .

Tsvina inotaridzika sei kana uine C. diff? Inonhuhwirira sei?

Manyoka eC. diff anowanzova nechimiro chakafanana nepaste, kwete mvura zvachose. Dzimwe nguva anogona kunge ari matema, asi izvi zvinogonawo kuitika kune mamwe mabhakitiriya. Kashoma, ropa, madzihwa, kana matumbu zvinogona kuonekwa mutsvina. Vanhu vazhinji vanotaura kuti manyoka eC. diff ane hwema hwakasiyana . Vanoti ane hunhu husina kujairika uye ane kuravira kunotapira kunoshamisa. Izvi zvinogona kunge zvichikonzerwa nekuti C. diff inowedzera huwandu hwe bile acids mutsvina.

Chii chinokonzera hutachiona hweC. diff?

Kazhinji, munhu ane immune system ine hutano anochengetedza mabhakitiriya eC. diff mudumbu make, kuitira kuti asakonzere hutachiona. Dambudziko nderekuti mabhakitiriya aya paanotanga kukura zvakanyanya pasina kudzora kwakadaro. Chikonzero cheizvi ndechekuti kuenzana pakati pemabhakitiriya "akanaka" nemabhakitiriya "akaipa" mudumbu medu kunorasika. Munhu wese ane mabhakitiriya mudumbu make. Mabhakitiriya aya akanaka anobatsira kuchengetedza mamwe mabhakitiriya akaita seC. akasiyana mudumbu make. Chikonzero chikuru chehutachiona hweC. diff kushandiswa kwe `(antibiotics)`. Kana maantibiotics ashandiswa, kuenzana pakati pemabhakitiriya akanaka neakaipa mudumbu medu (`(gut microbiome)` kunokanganiswa. Ipapo mabhakitiriya eC. diff anogona kuva nesimba uye kukura zvakanyanya.

C. diff inotapuriranwa sei?

Clostridium difficile inopararira nekuburitsa spores. Spores idzi diki kwazvo uye dzinogona kuwanikwa paganda redu, pazvinhu zvakatikomberedza, uye pamusoro pematafura nezvigaro. Izvi zvinoreva kuti kana ukabata chimwe chinhu chine spores idzi, wobva wadya nacho kana kubata muromo wako, unogona kuwana C. diff.

Sei C. diff ichipararira nekukurumidza kudaro?

Kunze kwemiviri yedu, mabhakitiriya eC. diff anogadzira spores. Mabhakitiriya aya akaoma kuuraya, mukati nekunze kweura. Haapindi kupisa, acid, mishonga inorwisa mabhakitiriya yakawanda, uye mishonga inouraya utachiona. Anogonawo kurarama pamusoro pemvura kwemwedzi yakati wandei. Vaongorori vanofungidzira kuti vanhu vanosvika 5% vane mabhakitiriya eC. diff mumatumbu avo vasingakonzere zviratidzo. Izvi zvinoreva kuti kunyangwe uine C. diff pasi pekudzora, unogona kuparadzira kune vamwe.

Unogona here kushamwaridzana nemunhu ane chirwere cheC. diff?

Ehe, unogona. Asi chete kana ukatevera matanho ekuchengetedza. Kuti uderedze kupararira kwehutachiona, unofanira kuita zvinotevera:

• Gara uchigeza maoko ako nesipo zvakanaka.
• Dzivisa kubata mhino yako, muromo, nemaziso.
• Bvisa utachiona panzvimbo dzakapoteredza.
• Magurovhosi, masiki ekumesoShandisa midziyo yekudzivirira, yakadai semagown (kunyanya kana uchitarisira murwere).

Ndiani ari panjodzi huru yekubatwa nechirwere cheC. diff?

Kune mamwe matambudziko ehutano anogona kuderedza dziviriro yemuviri wako kubva kuhutachiona hweC. diff. Izvi zvinosanganisira:

• Chirwere cheInflammatory Utumbo ( IBD ): Zvirwere zvemudumbu zvinogara kwenguva refu, zvakaita seCrohn's disease neulcerative colitis, zvinoderedza simba remudumbu nekufamba kwenguva. Izvi zvinokuvadza mucosa, jira remudumbu, uye zvinoderedza dziviriro yemuviri kuzvirwere zvemudumbu.
• Kusasimba kwemuviri : Kana uine chirwere chekushaya simba kwemuviri kana chimwe chirwere chisingaperi chinokanganisa muviri wako, chakadai sekenza, HIV , chirwere cheitsvo, kana chirwere cheshuga, muviri wako wese unogona kunge usina simba, kwete ura hwako chete. Izvi zvinonyanya kuitika kana uri kutora mishonga inodzvinyirira muviri.

Zvimwe zvinhu zvine njodzi zvinosanganisirwa nehutachiona hweC. diff zvinosanganisira:

• Zera: Vanhu vane makore anopfuura 65 vane njodzi huru yekubatwa neC. diff. Izvi zvinogona kunge zvichikonzerwa nekuti vane masoja emuviri asina simba, vari kutora mishonga yakawanda panguva imwe chete, kana kuti vanogara muzvipatara kana mudzimba dzevakwegura. Vana vadiki vanogonawo kubata C. diff.
• Kupinda muchipatara kana munzvimbo dzine vanhu vakawanda (semuenzaniso, majeri): C. diff inopararira zviri nyore munzvimbo dzine vanhu vakawanda. Mabhakitiriya anogona kugara kwemwedzi yakawanda panzvimbo dzakafanana. Inogona kupararira kubva kumunhu kuenda kune mumwe kuburikidza nenzvimbo dzinoshandiswa nevanhu vakawanda, dzakadai sedzimba dzekugezera.

Asi dzimwe nguva hapana chikonzero chakajeka chehutachiona hweC. diff. Kunyange zvazvo paine zvinhu zvakawanda zvinogona kukanganisa masoja emuviri wako, zvakakosha kuziva kuti unogona kuwana hutachiona uhwu kunyangwe pasina zvinhu zvinokuvadza .

Ndezvipi zvinetso zvinogona kuitika nekuda kwehutachiona hweC. diff?

Matambudziko anogona kuitika kana utachiona hwacho hwanyanya kuoma. Kuti hutachiona hwako hwakanyanya sei zvinoenderana nezvinhu zvakati wandei, kusanganisira rudzi rwebhakitiriya raunaro, uye simba remasoja emuviri wako. Vanhu vane zvinhu zvinokonzera hutachiona hweC. diff vari panjodzi huru yekuwana hutachiona hwakanyanya kana kuva nehutachiona hunodzokororwa. Izvi zvinogona kukonzera kukuvara kwakawanda nekufamba kwenguva. Matambudziko akajairika anosanganisira:

• Utachiona hunodzokororwa: Vanhu vanosvika 20% vanohuwana zvakare mukati memavhiki maviri kusvika masere mushure mekupedza kurapwa. Mushure meizvozvo, vamwe 40% vanogona kuhuwana zvakare.
• Kushaya mvura mumuviri uye kurasikirwa nema electrolytes:Kana ukarasikirwa nemvura nemaelectrolyte mumuviri wako nekukurumidza kupfuura zvaunogona kutsiva, unogona kuva nemigumisiro ine njodzi senge kushaya ropa rakawanda, BP yakaderera, uye kutotadza kushanda zvakanaka kweitsvo muzviitiko zvakakomba.
• Pseudomembranous colitis: Iyi imhando yecolitis yakanyanya. Mumamiriro ezvinhu aya, membrane yakakora, ine goko inogona kuumbwa pamusoro peura rako.

Sezvo kukuvara kunokonzerwa nehupfu muura kuchiwedzera, mamwe matambudziko anogona kuitika:

• Kubuda kwemvura: Mvura inogona kutanga kubuda kubva muura wako ichienda mudumbu rako (izvi zvinonzi ascites), zvichiita kuti dumbu rako rizvimbe. Unogonawo kurasikirwa nemapuroteni kubva muura wako, zvichiita kuti mazinga e albumin adzike. Izvi zvinogona kukonzera zviratidzo zvakaita sekuzvimba uye kuneta.
• Reactive arthritis: Utachiona hwakakomba hunogona kukonzera chirwere chinonzi "reactive arthritis." Izvi zvinogona kukonzera kuzvimba, kuzvimba, uye kurwadziwa mumajoini ako nedzimwe nhengo dzemuviri wako.
• Megacolon ine chepfu: Megacolon ine chepfu chirwere chisingawanzoitiki asi chine njodzi zvikuru. Izvi zvinoitika kana kuzvimba kunokonzerwa nekuzvimba kwacho kwakanyanya zvekuti ura hunotanga kusashanda zvakanaka. Izvi zvinogona kupedzisira zvakonzera sepsis (chepfu muropa).

Utachiona hweC. diff hunoonekwa sei?

Kana chiremba wako achifungidzira kuti une hutachiona hweC. diff zvichienderana nezviratidzo zvako, achatora sampuli yetsvina yako oitumira kurabhoritari kuti iongorore chepfu yeC. diff. Kana zvabuda muongororo yako zvikaonekwa kuti zvine chepfu, zvichireva kuti une hutachiona, chiremba wako anogona kuita mimwe miedzo kuti aone kuoma kwehutachiona. Izvi zvinogona kusanganisira kuongororwa kweropa uye bvunzo dzemifananidzo kuti aone mukati meura rako.

Utachiona hweC. diff hunorapwa sei?

Utachiona hweC. diff hunorapwa zvichienderana nekuoma kwahwo. Kana wakatanga kushandisa C. diff uchitora mishonga inorwisa mabhakitiriya, chiremba wako anogona kutanga arega kutora mushonga wacho. Kune vamwe vanhu, ndizvo chete zvinodiwa. Masoja avo emuviri anozotanga kushanda zvakare uye anotonga hutachiona. Kana zvikasadaro, chiremba wako anogona kunyora mamwe marudzi emishonga inorwisa mabhakitiriya inogona kumisa C. diff. Mamwe marudzi emishonga inorwisa mabhakitiriya eC. diff anosanganisira:

• `(Metronidazole)`
• `(Vancomycin)`
• `(Fidaxomicin)`

Kana uine hutachiona husina kunyanya kuoma, unogona kuenda kumba wonotora mushonga wako. Vanhu vazhinji vanotanga kupora mumazuva mashoma. Asi kana hutachiona hwacho hwakanyanya, uchafanira kugara muchipatara. Muchipatara, chiremba wako achakupa mishonga inorwisa mabhakitiriya, pamwe kuburikidza netsinga (IV - intravenous). Vachakupawo zvinhu zvakaita semunyu kudzivirira kupera mvura mumuviri. Mune zvimwe zviitiko, mushonga wacho unogona kupihwa zvakananga muura se enema.

Chii chekuita nehutachiona hweC. diff hwakaoma?

Kana uine matambudziko akakomba, ungangoda kurapwa muchikamu chevanorwara zvakanyanya. Kashoma, vanachiremba vanogona kukurudzira kuvhiyiwa kwechimbichimbi (colectomy) kubvisa kwakabva hutachiona muura hwako. Kana ukapora asi ukaramba uchiwana hutachiona hunoramba huchidzoka mushure mekurapwa, sarudzo dzako ndeidzi:

• Kurapwa nemishonga inorwisa mabhakitiriya zvakare: Chiremba wako anogona kukupa mushonga wakasiyana, kana mushonga mumwe chete kwenguva yakareba. Mushure mekushandisa mishonga inorwisa mabhakitiriya, chiremba wako anogonawo kukurudzira kutora mishonga inorwisa mabhakitiriya kuti ubatsire kudzoreredza mabhakitiriya ari mudumbu mako.
• Kudyara Fecal Microbiota Transplant (FMT): Nzira iyi yakaratidzwa kuti inoshanda zvikuru mukudzivirira kudzoka kwezvirwere zveC. diff mushure mekunge kurapwa nemishonga inorwisa mabhakitiriya kwakundikana. Inosanganisira kutamisa sampuro yetsvina kubva kumunhu ane hutano kuenda muura hune chirwere. Sampuro iyi inoshandiswa kugadzirisa microbiome yemudumbu mako. Funga nezvazvo sekuwedzera ivhu rakanaka mubindu rine zvirimwa zvisina kunaka uye kudyara zvirimwa zvakanaka.

Ndezvipi matanho ekuchengetedza anogona kutorwa kudzivirira kupararira kweC. diff?

Vashandi vezvehutano vanotora matanho akakosha ekudzivirira kana vachibata nehutachiona hweC. diff kuti vabatsire kudzivirira kupararira kwechirwere ichi chinotapukira zvikuru. Unogona kutevedzera muenzaniso wavo kudzivirira vamwe:

• Kuzviparadzanisa: Kana uine hutachiona, zvakanaka kuzviparadzanisa mukamuri rako wega. Munhu wese anouya mukamuri kuzokutarisira anofanira kupfeka magirovhosi anoraswa, uye anofanira kuabvisa paanobuda mukamuri. Sezvo hutachiona hwacho huchipararira netsvina yako, unofanira kudzivisa kushandisa zvimbuzi nevamwe vanhu. Kana uchifanira kushandisa chimbuzi, geza mubato, chigaro chechimbuzi, nenzvimbo yakapoteredza nechinhu chinochenesa chine bleach mushure mekuchishandisa.
• Kugeza maoko: Nekuti C. diff haikanganisike ne sanitizer yemaoko, zvakakosha kugeza maoko ako nguva nenguva nesipo nemvura inopisa. Izvi zvakakosha kune wese munhu waunosangana naye.
• Kuuraya utachiona: Mishonga yakawanda yekuuraya utachiona haishande paC. diff. Asi mishonga ine bleach inogona. Zvakakosha kubvisa utachiona pane chero nzvimbo dzaunobata, kunyanya muimba yekugezera.
• Kutora mishonga inorwisa mabhakitiriya sezvakarairwa: Usatore mishonga inorwisa mabhakitiriya yevamwe vanhu, uye usachengete mishonga inorwisa mabhakitiriya kuti uzoishandisa gare gare.

Chii chaungatarisira kana ukawana C. diff?

Utachiona hwakawanda hweC. diff hunononoka uye hunopera kana ukarapa. Zvisinei, zvirwere zvinokonzera C. diff zvinogona kupararira nekukurumidza. Utachiona hweC. diff hunogona kungoerekana hwavapo uye hwakanyanya. Kana uine zvinhu zvinokonzera C. diff, une mukana wekutapukirwa nehutachiona hwakakomba, kana kuti ungave nehutachiona hunodzokorora hunoda kurapwa kwakawanda.

Ko C. diff inopera yoga here?

Ehe, kana mabhakitiriya ako emudumbu akagwinya akakwanisa kudzokera pakare uye kurwisa, unogona kuzvigadzirisa wega. Izvi zvinowanzoitika kana mabhakitiriya ako emudumbu akasimba uye usina matambudziko ehutano kwenguva refu ari kuaderedza simba. Kana hutachiona hwacho hwakakonzerwa nekutora mishonga inorwisa mabhakitiriya, unogona kuzvigadzirisa kana warega kuatora. Asi usamirire kwenguva yakareba. Kana usinganzwe zviri nani mukati memazuva mashoma, enda kuna chiremba nekukasika.

Kana wangowana C. diff, inogara iripo here?

Mushure mekurapwa, mamwe mabhakitiriya anogona kuramba aripo. Asi unogona kugara kwenguva yakati usina hutachiona. Chero bedzi mabhakitiriya akanaka ari mudumbu aripo, anobatsira kudzora Clostridium difficile. Kana ukawana hutachiona hunodzokororwa, imhaka yekuti mamwe mabhakitiriya aya haasati adzokera pahunhu hwawo. Kudzokororwa kwehutachiona kunogona kudzokorora hutachiona hwepakutanga, asi handizvo zvinoitika nguva dzose. Dzimwe nguva hutachiona hutsva.

Pane matambudziko enguva refu here mushure mehutachiona hweC. diff?

Dambudziko rinowanzoitika kwenguva refu hutachiona hunoramba huripo kana kuti hunodzokororwa neClostridium difficile. Izvi zvinoitika kana ura hwako huchiomerwa nekupora zvachose. Hura hwako hunogona kunonoka kupora nekuda kwezvikonzero izvi:

• Kana wakambova nechirwere chakakomba chakakuvadza ura hwako.
• Kana waifanira kutora mishonga inorwisa mabhakitiriya kwenguva yakareba, kana kuti waifanira kutora mishonga inorwisa mabhakitiriya yeC. diff mushure mekutora mimwe mishonga inorwisa mabhakitiriya.
• Kana uine chirwere chehutano chinogara kwenguva refu chinokanganisa ura hwako kana masoja emuviri.
• Kana une makore anopfuura makumi matanhatu nemashanu ekuberekwa.

Kashoma kuti vamwe vanhu vabatwe nezvirwere zve autoimmune mushure mekubatwa nechirwere chakakomba. Izvi zvinoreva kuti masoja avo ekudzivirira muviri anoramba achiita sekunge pane chirwere, kunyangwe chirwere chacho chapera. Zvirwere zve autoimmune zvinogona kutanga mushure mekubatwa nechirwere cheC. diff zvinosanganisira post-infectious IBS (irritable bowel syndrome) uye reactive arthritis.

Mibvunzo ipi yaunofanira kubvunza chiremba wako nezvechirwere cheC. diff?

Unogona kubvunza mibvunzo yakaita seiyi:

• Utachiona hwangu hwakaipa zvakadii?
• Ndiri panjodzi yekusangana nematambudziko here?
• Ndingaziva sei kana C. diff iri kuvandudzika?
• Ndinofanira kukufonerai riini? Ndinofanira kuenda kuchipatara riini?
• Ndinofanira kuona gastroenterologist here?
• Ndezvipi zvingasarudzwa zvekurapa hutachiona hunodzokororwa?

Clostridium difficile ibhakitiriya yakajairika inogona kugara muura hwako isingakuvadzi. Asi kana ikatanga kusimba zvakanyanya, inogona kuva yakakomba zvikuru. Unganzwa uchinetseka nezvekuva nemanyoka nguva dzese uye kuti ari kukanganisa sei hupenyu hwako. Unganzwawo kunyara kutaura nezvechirwere chinokanganisa kufamba kwedumbu rako. Asi usarega manzwiro iwayo achikudzivisa kutsvaga rubatsiro.Vanhu vazhinji havaiti matambudziko anokonzerwa neC. diff, uye inopera nekukurumidza uye zvachose. Asi kana uri panjodzi yakakura nekuda kwezvimwe zvinhu zvinogona kukonzera njodzi, inogona kuva yakanyanya. Inotapukirawo zvakanyanya, inogona kuramba iripo, uye inogona kudzoka kakawanda. Kana ukaita manyoka mushure mekutora mishonga inorwisa mabhakitiriya, udza chiremba wako nekukasika. Usatore mishonga inomisa manyoka, sezvo isingabatsire uye inogona kutowedzera kuipa. Kana uchifungidzira kuti une C. diff, enda kuna chiremba nekukasika.

Saka, ndezvipi zvinhu zvatinofanira kurangarira kubva munyaya iyi?

C. diff ibhakitiriya inogona kukonzera hutachiona muura hwedu hukuru. Izvi zvinokonzera zviratidzo zvakaita semanyoka uye kurwadziwa kwemudumbu.

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Izvi zvinowanzoitika kana mishonga inorwisa mabhakitiriya inouraya mabhakitiriya akanaka ari mudumbu, zvichiita kuti C. diff ikure.

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Izvi zvinotapuriranwa zvakanyanya, saka kugeza maoko ako nekuchengetedza hutsanana kwakakosha zvikuru.

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Vakwegura, avo vane masoja emuviri asina simba, uye avo vari muchipatara vane mukana mukuru wekuwana chirwere ichi.

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Kana uine zviratidzo, tsvaga rubatsiro rwechiremba nekukasika. Nekuti, kana ukarapwa zvakanaka, unogona kupora kazhinji. Zvisinei, kana ukasarapwa, matambudziko anogona kuitika.

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Zvakakosha kutora mushonga wako sezvakarairwa nachiremba wako uye nenguva.

Saka, ndinovimba ruzivo urwu ruchakubatsira. Ramba uine hutano hwakanaka!