Mushonga wekuzvimba mudumbu uye gastritis! Ngatidzidzei chaizvo nezveProton Pump Inhibitors (PPIs)!

Unowanzo rwara nechirungurira kana kurwadziwa pachipfuva here? Kana kuti chiremba akati "gastritis"? Rudzi rwemushonga unowanzo pihwa navanachiremba muzviitiko zvakadaro unonzi `(Proton Pump Inhibitors)`. Dai taizotaura zvisina kujeka, pamwe taizotiwo "mushonga wegastritis." Saka, nhasi tichataura nezve `(Proton Pump Inhibitors)` kana kuti maPPI muchidimbu.

Sei tichida maPPI aya? Chii chinoitika kune acid yemudumbu?

Zvichitaurwa zviri nyore, `(Proton Pump Inhibitors)` rudzi rwemushonga unoderedza huwandu hweasidhi inogadzirwa mudumbu mako, kureva huwandu hweasidhi yemudumbu . Zvino ungave uchifunga kuti, "Oh, chii chine basa reasidhi yemudumbu? Hazvina kunaka." Izvozvo hazvisi zvechokwadi. Asidhi yemudumbu inokosha zvikuru kumiviri yedu. Ndiyo asidhi iyi inotibatsira kugaya chikafu chatinodya. Kwete izvozvo chete, asi asidhi yemudumbu iyi inobatsirawo kuparadza utachiona hunokuvadza hwatinodya nechikafu tisingazive.

Zvisinei, dzimwe nguva matambudziko anotanga kana huwandu hweasidhi yemudumbu hukawedzera zvakanyanya, kana kuti acid ikaenda kune imwe nzvimbo isiri iyo inofanira kunge iri. Zvakafanana nechirevo chinoti "Kana ikawedzera, nectar ichave ine chepfu." Ndipo panogona kuva nemaronda emudumbu (`ulcers`), kana sezvatinoadaidza, "gastritis ulcers". Zvimwe zvinhu zvakaita sechirungurira uye kuravira kunovava pahuro zvinogonawo kuitika. Ndipo panogonawo kuva nemishonga iyi inonzi PPIs. Inonyanya kushandiswa kumatambudziko enguva refu ane chekuita neasidhi yemudumbu.

MaPPI aya anoshandiswa kuzvirwere zverudzii?

Vanachiremba vanoshandisa mishonga iyi zvakanyanya (Proton Pump Inhibitors) kurapa zvirwere zvakaita sekukuvadzwa nekuzvimba kwezvikamu zvemudumbu, kureva ura negurokuro, zvinokonzerwa neacid yemudumbu. Ngationei kuti chii:

• GERD kana kuti Chronic Acid Reflux Disease: Unowanzo rwara nechirungurira here? Une kuravira kunovava pahuro here? Ndizvo zvakaita GERD. Zvichitaurwa zviri nyore, iasidhi iri mudumbu rako inouya mugurokuro. Izvi zvinogona kukuvadza jira regurokuro, iro rinonziwo erosive esophagitis. MaPPI anoshanda nekuderedza kugadzirwa kweasidhi mudumbu uye kupa gurokuro nguva yekupora.
• Maronda emudumbu nedumbu: Maronda emudumbu nedumbu maronda anogona kukonzerwa neacid yemudumbu, iyo inogona kukuvadza jira rinodzivirira remudumbu. Anogonawo kukonzera maronda muchikamu chekutanga cheura diki (chinonzi duodenum). MaPPI anogona kubatsira kuporesa maronda aya. Pamusoro pezvo, mimwe mishonga inoderedza marwadzo, kunyanya mishonga isingarwisi kuzvimba (NSAIDs), inobatanidzwa nenjodzi yakakura yekuva nemaronda. Zvidzidzo zvinoratidza kuti vanhu vanosvika 30% vanotora maNSAIDs vanogara vachiva nemaronda. MaPPI anogona kubatsira kudzivirira nekuporesa maronda.
• Utachiona hweH. pylori:Urwu rudzi rwebhakitiriya rinogona kugara mudumbu medu. Urwu utachiona hunogonawo kukonzera maronda emudumbu. Pakurapa hutachiona hweH. pylori, vanachiremba vanopa maPPI pamwe chete nemishonga inorwisa mabhakitiriya. Izvi zvinokonzerwa nekuti maPPI anochinja pH yemudumbu, zvichiita kuti zvive nyore kuti mishonga inorwisa mabhakitiriya iuraye.
• Zollinger-Ellison syndrome: Ichi chirwere chisingawanzoitiki. Muchirwere ichi, mamwe marudzi emabundu (`mabundu`) anokura mumuviri uye anoita kuti muviri ugadzire hormone yakawandisa inokonzera acid yemudumbu. Izvi zvinoguma neacid yemudumbu yakawandisa. MaPPI anoshandiswawo kurapa chirwere ichi.

Mishonga iyi inonzi maPPI inoshanda sei? Zvinoshamisa, handiti?

Fungidzira kuti pane "muchina" mudumbu medu unogadzira acid. Tinoti muchina uyu "hydrogen-potassium ATPase pump", kana kuti "proton pump" muchidimbu. Kungofanana nepombi yemvura inodhonza mvura, pombi iyi yeproton ndiyo inoita maitiro emakemikari anodiwa kugadzira acid mudumbu.

Saka, zvinoitwa neaya ma "Proton Pump Inhibitors" kana maPPI kumisa kushanda kweproton pump kwenguva pfupi . Kureva kuti, "vanoidzivisa", kureva kuti, vanoikanganisa. Ipapo kugadzirwa kweacid mudumbu kunoderera.

Asi izvi hazvimisi zvachose kugadzirwa kweasidhi yemudumbu, handiti? Uchiri neasidhi yakakwana yekugaya chikafu. Kana ukatora PPI kwemazuva mashanu akatevedzana, kugadzirwa kweasidhi yemudumbu kuchaderedzwa neinenge 65%. 35% yasara yeasidhi yakakwana kugaya chikafu.

Ndezvipi maPPI aya?

Mamwe emaPPI aya anogona kutengwa pasina kunyorerwa mushonga (OTC) ku pharmacy pasina kunyorerwa mushonga, asi mamwe akasimba anoda kunyorerwa mushonga nachiremba (Rx chete).

MaPPI anogona kutorwa netsamba yachiremba kana kuti asina kunyorerwa nachiremba (OTC neRx):

• Esomeprazole (Nexium®)
• Lansoprazole (Prevacid®)
• Omeprazole (Prilosec®)
• Omeprazole/sodium bicarbonate (Zegerid®)

MaPPI anowanikwa chete kana chiremba aakanyora (Rx chete):

• Dexlansoprazole (Dexilant®)
• Pantoprazole (Protonix®)
• Rabeprazole (AcipHex®)

Ndingatora mushonga uyu sei? Ndinofanira kutora mushonga wakawanda sei?

Mishonga iyi inouya muchimiro chepiritsi kana kuti chekapusule. Unoinwa nemuromo. Mamwe marudzi emakapusule ane hupfu hunogona kusanganiswa muchikafu, senge applesauce, wobva wainwa. Izvi zvinobatsira zvikuru kune vanhu vane dambudziko rekumedza mapiritsi.

Usati watora mushonga, unofanira kuverenga mirairo iri papakeji nokungwarira.Ndipo paunowana mhinduro dzakarurama. Kune mamwe maPPI aunofanirwa kunwa hafu yeawa kana awa usati wadya, usina chinhu mudumbu. Paunoatora panguva iyoyo, mushonga wacho une nguva yekushanda mudumbu mako usati watanga kugadzira acid paunodya.

Chiremba wako chete ndiye anogona kukuudza mushonga chaiwo waunoda ('dose') uye kuti unofanira kuunwa kangani pazuva. Iye achakupa mushonga unodzora zviratidzo zvako pasina mukana wekuti pave nemigumisiro yakaipa. Kune vamwe vanhu, kutora piritsi rimwe chete usati wadya kudya kwemangwanani kwakakwana. Kune vamwe, kuritora kaviri pazuva, usati wadya kwemangwanani uye usati wadya kwemanheru, kunogona kukwana. Dzimwe nguva, kuritora mazuva ese maviri kunogona kukwana.

Nekufamba kwenguva, ungangoda kuderedza mushonga wako. Chiremba wako achakupawo mazano panyaya iyi.

Zvinotora nguva yakareba sei kuti maPPI aya ashande?

Mushure mekutora mushonga wePPI, zvinogona kutora chero nguva kubva pamaawa makumi maviri nemana kusvika kumazuva mana kuti unzwe kushanda kwawo zvizere.

Kana ukangoerekana wava nechirungurira kana kurwadziwa pachipfuva uye uchida rubatsiro rwekukurumidza, zviri nani kushandisa mushonga unorwisa asidhi (wakaita seDigene, Acidex) kana mushonga unodzivisa histamine (H2 blocker) (wakaita sePepcid® kana Tagamet®) pane kushandisa maPPI. Fungidzira kuti unongoerekana wava nechirungurira mushure mekudya chikafu chine munyu. Zvadaro, kutora mushonga wakadaro kuchapa zororo mukati memaminitsi mashoma kana maawa mashoma. Zvisinei, kushanda kwawo hakugari kwenguva yakareba semaPPI.

MaPPI anobatsira kana uine matambudziko emudumbu kwenguva refu uye asingapere.

Pane migumisiro yakaipa here pakushandisa maPPI aya?

Vanhu vazhinji havana matambudziko makuru pavanotora maPPI. Zvisinei, kufanana nemishonga ipi zvayo, anogona kukonzera mamwe matambudziko. Izvi zvinosanganisira:

• Marwadzo emudumbu
• Kuzvimba
• Manyoka
• Dzungu
• Muromo wakaoma
• Musoro
• Kupindwa nechando
• Kuzvimba/Gasi
• Kureruka kwemusoro
• Kukwenya uye mapundu
• Kurutsa

Kunyange hazvo maPPI achiwanzoonekwa seakachengeteka, vaongorori vakaona kuti anogona kukonzera njodzi, kunyanya kana akashandiswa kwenguva yakareba . Ngatitarisei kuti chii:

• Utachiona hweClostridioides difficile (C. diff): MaPPI anogona kushandura kuenzana pakati pemabhakitiriya akanaka neakaipa mudumbu mako, zvichiwedzera njodzi yako yekubatwa nezvirwere zvakaita seC. diff.
• Kutyoka: MaPPI anogona kuderedza kugona kwemuviri wako kupinza calcium, mineral inobatsira kuchengetedza mapfupa edu akasimba. U.S. Food and Drug Administration (FDA) inonyevera kuti maPPI anogona kuwedzera njodzi yekutyoka muhudyu, ruoko, kana musana.
• Chirwere cheitsvo:Izvi zvinogona kuwedzera njodzi yekubatwa nechirwere cheitsvo chisingaperi (CKD), kana kuita kuti mamiriro ezvinhu aripo awedzere kuipa.
• Kushaikwa kwekudya kunovaka muviri: MaPPI anogona kuderedza kugona kweura hwako kupinza magnesium kana vhitamini B12 muropa. Magnesium imineral inobatsira tsandanyama dzedu netsinga kushanda zvakanaka. Vhitamini B12 inokosha kuhurongwa hwedu hwetsinga nemasero matsvuku eropa.

Kubatana kuripo pakati pePPI nezvinhu izvi zvine njodzi kuchiri kudzidzwa. Zvisinei, vanachiremba vanowanzo kurudzira kushandisa mushonga wakaderera uye kwenguva pfupi kusvika zviratidzo zvako zvava nani. Izvi zvinoderedza njodzi yezvinhu izvi zvine njodzi.

Ndinofanira kuona chiremba wangu rini?

Kana chiremba akakunyorera maPPI, iva nechokwadi chekubvunza chiremba wako kana uine mibvunzo nezvekutora mushonga, nguva yekurega, kana kuti ungaderedza sei mushonga wacho.

Kana uri kutora maPPIs usina kutenga kubva ku pharmacy uye uchinzwa sekuti unoada zuva nezuva kuti udzore zviratidzo zvako, unofanira kuramba uchienda kunoona chiremba. Iye anogona kukuudza nezvemushonga chaiwo uye nguva yaunofanira kutora.

Uyewo, kana ukasangana nemhedzisiro iyi ine njodzi, enda kuna chiremba nekukasika:

• Kurwara nepfungwa (mapundu eganda, kutsvuka, kuzvimba)
• Zviratidzo zvekukuvadzwa kweitsvo (kungoita weti shoma kupfuura kare, kuzvimba mumaoko netsoka, zvitsitsinho)
• Zviratidzo zvekushaikwa kwemagnesium (kudedera, kurova kwemoyo kusina kurongeka, kugwinha kwetsandanyama)
• Zviratidzo zvekushaikwa kwevhitamini B12 (kurwadziwa mumaoko netsoka, kusanzwa, kukwenya, dzungu, kuvhiringidzika)
• Kana ganda rikatsvuka, rikaita maronda, kana kuti rikaita seriri kubvuuka
• Kana uine manyoka akanyanya
• Kana uine fivha

Saka, chii chinorehwa nemashoko ekupedzisira ekuenda nawo kumba?

Kuva neacid yakawanda mudumbu, kana kuva nayo panzvimbo isiriyo, kunogona kurwadza zvikuru. Zvinogonawo kukuvadza kugaya kwako. Nerombo rakanaka, kune mishonga yakawanda inogona kubatsira kana uine zviratidzo izvi.

Kuti unzwe zviri nani kwenguva pfupi, mushonga unorwisa asidhi kana kuti H2 blocker ndiwo wakanakisa. Asi kana uchigara uchirwara nechirungurira kana kuti uine maronda emudumbu, chiremba wako anogona kukupa mhando yePPI. Mishonga iyi yave iripo kwemakore uye inoonekwa senzira yakachengeteka uye inoshanda yekurapa. Vanhu vazhinji vanowana zororo nemishonga iyi.

Chinhu chinonyanya kukosha ndechekuti mushonga uyu unofanira kushandiswa chete kana chiremba akuudza, muchiyero chakanyorwa uye kwenguva yakatarwa.Kana ukaedza kuishandisa nenzira yaunoda, matambudziko anogona kumuka. Saka, kuchenjera kugara uchiteerera zvinotaurwa nachiremba uye kunwa mushonga zvinoenderana nawo.

MaPPI , gastritis, kuzvimba kwemudumbu, acid reflux, maronda emudumbu, omeprazole, pantoprazole