Ubusazi na ngemithambo yegazi emincinci (ii-capillaries ezixineneyo) ezinee-'windows' emzimbeni wakho?

Ngaba wakha wazibuza ukuba ibaluleke kangakanani imithambo yegazi emincinci engaphakathi emizimbeni yethu, ebizwa ngokuba yi-capillaries? Ezinye ii-capillaries zinemingxuma emincinci efana 'neefestile' kuzo. Yiloo nto siyibiza ngokuba yi-fenestrated capillaries. Namhlanje, masithethe ngale mithambo yegazi imangalisayo, ukuba yintoni, iphi, yenza ntoni, kwaye singayigcina njani isempilweni.

Zithini ezi capillaries zifakwe i-fenestrated?

Kulungile, makhe sijonge ukuba zeziphi ezi capillaries zi-fenestrated. Igama lesiLatini elithi 'fenestrae' lithetha 'ifestile.' Ngoko ke le mingxunya mincinci kwezi capillaries, njengeefestile, ivumela amasuntswana amakhulu kunye neeproteni, njengegazi, ukuba zidlule ziye kwizitho zethu ezibalulekileyo kunye namadlala. Ngamafutshane, zisebenza njengenkqubo ekhethekileyo yokucoca . Zilapho imizimba yethu itshintshiselana khona oko ikudingayo nalapho ingafuniyo.

Ziphi ezi zinto emizimbeni yethu? Yintoni umsebenzi wazo?

Ngoku usenokuba uzibuza, 'Ziphi ezi zinto emizimbeni yethu? Zenza ntoni?' Ii-capillaries ezine-fenestrated zifumaneka ngobuninzi kwizintso zethu, emathunjini amancinci , kwi-pancreas, nakwii -endocrine glands . Ezi zitho zihlala zifuna ukutshintshiselana ngezondlo kunye nemveliso emdaka phakathi kwee-capillaries kunye nezicubu. Ii-pores kwezi capillaries zenza olu tshintshiselwano lube lula kakhulu.

Iyintoni indima yezi zinto kwizintso?

Ii-Capillaries ezine-Fenestrated zibaluleke kakhulu kwizintso zethu. Izintso zineyunithi zokucoca ezibizwa ngokuba zii-nephrons . Khawucinge nje, kukho malunga nesigidi sezi-nephrons kwintso enye! Ayimangalisi loo nto? Ngaphakathi kwi-nephron nganye kukho iqela lee-capillaries ezine-fenestrated eziqokelelwe ndawonye njengebhola. Oku kubizwa ngokuba yi-glomerulus . Oku kusebenza njengesihluzo esiphambili .

Ayipheleli apho, kodwa kukwakho nezinye ii-capillaries ezine-fenestrated ezijikeleze imijelo engaphakathi kwi-nephrons. Zidibene, ezi zinceda izintso ukuba zihluze inkunkuma egazini, zenze umchamo, kwaye ziphinde zifunxe izondlo ezifunekayo emzimbeni. Kufana nesihluzo samanzi endlwini yethu, kodwa siyinkimbinkimbi ngakumbi.

Ezi zinto zinceda njani ezinye izivamvo?

• Kwithumbu elincinci: Ezi capillaries zinceda ekufunxeni izondlo ekutyeni esikutyayo. Ezi mingxunya zivumela izinto ezifana neevithamini kunye neeminerali ukuba zingene lula egazini.
• Ukuba uthatha i-pancreas: Kubalulekile ukongeza ii-enzymes kunye nee-hormones egazini ezinceda ekugayeni ukutya, ingakumbi iswekile namafutha.
• Kwi-endocrine glands:Ezi gland zithumela iihomoni emzimbeni wethu wonke. Ezi homoni zilawula izinto ezininzi, kuquka imeko yethu yeemvakalelo kunye nokukhula. Ezi capillaries nazo zifuna uncedo kuloo nto.

Zibukeka njani ezi capillaries ezine-fenestrated?

Cinga ngendlela ezi zincinci ngayo ezi capillaries. Uninzi lwee capillaries lububanzi obuyi- 3 okanye i-4 micrometers kuphela. Oko kufana nobukhulu be spider web! Ithambile kakhulu, akunjalo? Zinee-layers ezimbini zeeseli.

Umaleko ongaphakathi weeseli ubizwa ngokuba zii-endothelial cells . Umaleko ongaphandle ubizwa ngokuba zii-epithelial cells . Ngamanye amaxesha oogqirha babiza oku ngokuba yi-basement membrane .

Ii-capillaries ezine-fenestrated zibonakaliswa yimingxunya emincinci kumaleko wazo wangaphakathi. Umngxuma ngamnye (okanye 'ifestile') une-membrane encinci. Isebenza njenge -diaphragm , isiciko esincinci esinokuvulwa sivalwe. Le membrane ivumela amasuntswana amakhulu (afana neeminerali) ukuba adlule kule mingxunya ngokulula.

Ziziphi izifo ezichaphazela la ma-capillaries?

Ngoko ke, nee-capillaries ezine-fenestrated, ezenza umsebenzi obaluleke kangaka, ngamanye amaxesha zinokuba nezifo.

• Isifo Sezintso Esingapheliyo (CKD): Abantu abanale meko badla ngokuba neengxaki ngezi capillaries. Ngokukodwa, ii-peritubular capillaries ezikwizintso zinokonakala. Ezi zinto zinceda ekuhluzeni imveliso engcolileyo evela kwizintso. Ukunqongophala kweVithamin D, ukudumba, kunye nezifo ezahlukeneyo zingonakalisa ezi capillaries kwaye zinciphise uxinano lwazo. Oogqirha babiza le meko ngokuba yi-capillary rarefaction . Xa oku kusenzeka, ii-capillaries zakho azisebenzi kakuhle. Oku kunokukhokelela kwi -hypertension , okukuxinzelelo lwegazi oluphezulu, kunye nezinye iingxaki zempilo.
• Ezinye izifo zezintso: Ezinye izifo zezintso, ezifana ne -glomerulonephritis, nazo zinokuchaphazela yonke inkqubo yokuhluza izintso. Isifo sezintso sixhaphake kakhulu. Ukuba asinyangwa ngokufanelekileyo, sinokukhokelela ekungasebenzini kwezintso .

Akukho namnye kuthi ofuna ukuba neengxaki zezintso, ngoko ke kubalulekile ukuba uzazi ezi zinto.

• I-Systemic Capillary Leak Syndrome (SCLS): Le yimeko engaqhelekanga kakhulu, kodwa enokuba yingozi ebomini. Ibangela umonakalo eludongeni lwee-capillaries. Oku kunokubangela ukwehla ngequbuliso koxinzelelo lwegazi.

Sizigcina njani ezi capillaries ziqinileyo ziphilile?

Ngoku usenokuba ucinga, 'Kulungile, ukuba ezi zinto zibaluleke kangaka, sizigcina njani ziphilile?' Enyanisweni, ukuze sigcine ezi capillaries ziqinileyo ziphilile, kufuneka sinikele ingqalelo kwimpilo yethu iyonke . Ezi capillaries zinceda iinkqubo ezininzi emzimbeni wethu zisebenze kakuhle. Ziyinxalenye yenkqubo yethu yokujikeleza kwegazi . Loo nkqubo iquka yonke eminye imithambo yegazi, imithambo yegazi, kunye nemithambo yegazi.

Iintlobo ngeentlobo zezifo zemithambo yegazi , okanye izifo ezinxulumene nemithambo yegazi, zinokuchaphazela ukusebenza kwazo zonke iintlobo zee-capillaries. Ngoko ke, kukho izinto ezimbalwa esinokuzenza ukuzikhusela kwezi zifo nakwezinye iingxaki zempilo:

• Kubalulekile ukuzilolonga nokuhlala usebenza. Ukuzilolonga yonke imihla kubaluleke kakhulu.
• Ukutya ukutya okunesondlo, ukunciphisa utywala, nokukhetha ukutya okunempilo kwintliziyo. Le yinto ethethwa ngumntu wonke kule mihla, kodwa ibaluleke kakhulu.
• Ukugcina ubunzima bakho busempilweni. Ukuba utyebile kakhulu okanye utyebile kakhulu , zama ukunciphisa umzimba.
• Ukuba unezifo ezingapheliyo ezifana nesifo seswekile kunye noxinzelelo lwegazi oluphezulu , kubalulekile ukuzilawula kakuhle. Kufuneka ulandele imiyalelo kagqirha ngononophelo.
• Ukuba ungumtshayi, yeka. Oku akuyonto ifanele ithathwe lula, yimbangela yezifo ezininzi.

Sifanele siye kugqirha nini malunga nezi capillaries?

Asisoloko siye kugqirha sicinga ngee-capillaries. Nangona kunjalo, ukuba kuvela iimpawu ezithile, kusenokwenzeka ukuba kungenxa yengxaki yezi capillaries zixineneyo.

Iimpawu zesifo sezintso:

Kufuneka ufune iingcebiso zonyango ngokukhawuleza, ingakumbi ukuba ubonisa iimpawu zesifo sezintso. Jonga ukuba unazo na ezi mpawu:

• Utshintsho kumchamo: Oku kungabandakanya igazi kumchamo (hematuria) , iproteni kumchamo (proteinuria) , okanye isidingo sokuchama rhoqo.
• Ukudinwa rhoqo, ubunzima bokugxila, okanye ubunzima bokulala.
• Ukutya akunancasa.
• Ukuba kukho ukudumba okanye ukudumba okujikeleze amehlo kangangeentsuku ezingaphezu kwezimbalwa.
• Ukuqaqamba kwemisipha.

Ukuba unenye okanye ngaphezulu kwezi mpawu, nceda ubone ugqirha ngokukhawuleza. Nangona ezi ziqhelekile ngamanye amaxesha, kubalulekile ukuqaphela ingxaki yezintso kwangethuba.

Iimpawu zeSystemic Capillary Leak Syndrome (SCLS):

Loo meko ingaqhelekanga kakhulu ekhankanyiweyo ngaphambili, iSystemic Capillary Leak Syndrome (SCLS), apho uxinzelelo lwegazi luyehla ngequbuliso. Le yingxamiseko yezonyango. Ukuba uxinzelelo lwakho lwegazi luyehla ngequbuliso kwaye unezinye zeempawu ezilandelayo, kufuneka ubone ugqirha ngoko nangoko okanye uye kwigumbi likaxakeka:

• Intlungu yesisu kunye nesicaphucaphu.
• Ukukhohlela nokuziva ngathi isifuba siqinile.
• Ukudumba (ukudumba), ingakumbi emilenzeni nasezingalweni.
• Ukudinwa kakhulu.
• Intloko ebuhlungu.
• Ukudinwa, isiyezi kunye nokuquleka.

Umyalezo esifuna ukuwuthatha ekhaya

Kulungile, ngoko ke ndicinga ukuba uyaqonda kakuhle la ma-capillaries ane-fenestrated esithethe ngawo namhlanje. Khumbula, la mithambo yegazi mincinci 'enefestile' iyinxalenye ebaluleke kakhulu kwinkqubo yethu yokujikeleza kwegazi. Ibalulekile ekuhluzeni inkunkuma evela kwizintso zethu, ekwenzeni umchamo, ekufunxeni izondlo emathunjini ethu, nasekuthumeleni iihomoni emzimbeni wethu wonke.

Ngoko ke, ukuze sigcine la ma-capillaries mancinci kodwa anamandla ephilile, kufuneka sikhathalele impilo yethu iyonke . Yitya ukutya okunesondlo, ugcine ubunzima obusempilweni, uhlale usebenza, kwaye ufumane uhlolo rhoqo njengoko kucetyisiwe ngugqirha. Ezi zinto ziya kuba luncedo olukhulu 'kwiifestile' zethu ezincinci kunye nomzimba wethu wonke. Uyayazi?

Ukuba unemibuzo engaphezulu malunga noku, ungathandabuzi ukuthetha nogqirha wakho wosapho. Uya kukwazi ukukunika ulwazi oluthe kratya.

IiCapillaries ezineFenestrated, iiCapillaries, izintso, iiNephrons, ukuhamba kwegazi, impilo