Ngaba umzimba wakho uvelisa i-insulin? Masifumanise ngovavanyo lwe-C-peptide!

Ubusazi na ukuba kukho uvavanyo olunokusixelela ulwazi oluninzi olubalulekileyo malunga nokukwazi komzimba wethu ukuvelisa ihomoni ebizwa ngokuba yi-insulin? Lubizwa ngokuba luvavanyo lwe-C-peptide. Usenokuba awuzange uve ngolu vavanyo ngaphambili. Kodwa lunokuba lubaluleke kakhulu kumntu onesifo seswekile okanye okrokrela ukuba unesifo seswekile. Makhe sithethe ngovavanyo lwe-C-peptide namhlanje, akunjalo?

Yintoni i-C-peptide? Kutheni ibalulekile kuthi?

Ngamafutshane, i-C-peptide yinto encinci eveliswa yipancreas yethu, ilungu esilibiza ngokuba yi-"Pancreas" ngesiNgesi, xa lenza i-hormone insulin. Ifana nemveliso encinci ephuma kumzi-mveliso xa kwenziwa imveliso ephambili. Ngoko ke, zombini i-C-peptide kunye ne-insulin ziveliswa ngokulinganayo yipancreas yethu.

Ngoku usenokuba uzibuza, "Ngoko ke yintoni i-insulin?" I-insulin yi-hormone ebaluleke kakhulu elawula inqanaba leswekile, okanye i-glucose, egazini lethu. I-insulin yiyo enceda iiseli zomzimba wethu zisebenzise i-glucose esiyifumanayo xa sisitya njengamandla.

Ngoku khangela, abantu abanesifo seswekile sohlobo loku-1 abakwazi ukwenza i-insulin kwaphela. Ngoko ke kufuneka bafake i-insulin ngaphandle. Kodwa abantu abanesifo seswekile sohlobo lwesibini bayayenza i-insulin, kodwa nokuba ubungakanani bayo abwanele, okanye iiseli zomzimba aziphenduli ngokufanelekileyo kuloo insulin (sikwabiza oku ngokuthi "ukuxhathisa i-insulin"). Ngamanye amaxesha abantu abanesifo seswekile sohlobo lwesibini nabo baba nokwehla kwemveliso ye-insulin ngokuhamba kwexesha kwaye kufuneka bathathe i-insulin ngaphandle.

Kulapho uvavanyo lwe-C-peptide luba lubalulekile khona. Kuba, nokuba umntu uthatha i-insulin ngaphandle, i-C-peptide ayizi naloo insulin. I-C-peptide iveliswa kuphela xa i-insulin iveliswa ngaphakathi emzimbeni. Ngoko ke, ngolu vavanyo, oogqirha bethu banokufumanisa ukuba ingakanani na i-insulin eveliswa ngaphakathi emzimbeni wakho, kwi-pancreas yakho. Oko kukuthi, inokuchaza umahluko phakathi kwe-insulin eveliswa ngumzimba (i-insulin engaphandle) kunye ne-insulin ethathwa njengeyeza (i-insulin engaphandle).

Olu vavanyo lukwabizwa ngokuba:

• Ukudibanisa i-peptide insulin
• I-insulin C-peptide
• I-Proinsulin C-peptide

Amanqanaba e-C-peptide anxulumene njani nesifo seswekile?

Into enye ekufuneka uyikhumbule kukuba uvavanyo lwe-C-peptide lodwa alunakukwazi ukuxelela ngokuqinisekileyo ukuba umntu unesifo seswekile okanye akanaso. Lukuxelela kuphela ukuba ipancreas yakho iyakwazi na ukuzenzela i-insulin yayo, okanye ingakanani.

Ukuze wazi ngokuqinisekileyo ukuba unesifo seswekile, ugqirha uza kukucela ukuba wenze uvavanyo lweglucose egazini, okanye uvavanyo lwe-A1c, olulinganisa amanqanaba akho eswekile egazini kwiinyanga ezintathu ezidlulileyo.

Kutheni ke oogqirha becebisa olu vavanyo lwe-C-peptide?

Kukho izizathu ezahlukeneyo zokuba ugqirha wakho angacebisa uvavanyo lwe-C-peptide. Makhe sijonge ukuba zeziphi ezi zinto:

• Cacisa uhlobo lwesifo seswekile onaso: oko kukuthi, misela ukuba luluhlobo 1 okanye uhlobo 2 (oku kwenziwa kunye nezinye iimvavanyo).
• Qinisekisa ukuba unyango lwakho lwesifo seswekile lusebenza kakuhle.
• Qinisekisa ukuba umzimba wakho uvelisa i-insulin eyaneleyo na, okanye ngaba udinga inaliti ye-insulin okanye ipompo ye-insulin.
• Fumana izizathu zokuba iswekile yegazi iphantsi: Oku sikubiza ngokuba yi-hypoglycemia.
• Qonda umahluko phakathi kwe-insulin eveliswa ngaphakathi kunye ne-insulin efakwa ngaphandle.
• Kunqabile kakhulu, oku kunokunceda ekunikeni ulwazi malunga nomhlaza wepancreatic.

Ngubani ovavanya i-C-peptide? Yenziwa njani?

Ngokwesiqhelo, umboneleli wakho oyintloko okanye ingcali ye-endocrinologist iya kucebisa uvavanyo lwe-C-peptide. Olu vavanyo ludla ngokwenziwa ngumongikazi okanye ingcali yelebhu.

I-C-peptide idla ngokulinganiswa ngokuthatha isampuli yegazi . Kwiofisi kagqirha, eklinikhi, okanye elebhu, umongikazi uza kufaka inaliti encinci emthanjeni osengalweni yakho aze aqokelele igazi elincinci kwityhubhu. Usenokuva intlungu encinci xa inaliti ifakwa, kodwa ayimbi kangako.

Ngamanye amaxesha olu vavanyo lunokwenziwa ngesampulu yomchamo . Kodwa xa usenza loo nto, kufuneka uqokelele wonke umchamo wakho kangangeeyure ezingama-24. Ukuba kunjalo, ugqirha wakho uza kukunika isitya sawo aze akunike imiyalelo yokuba ungawuqokelela njani uze uwubuyisele njani. Kusenokufuneka ugcine isitya kwindawo epholileyo, njengefriji. Kodwa oogqirha abasoloko besenza olu vavanyo lomchamo.

Ngaba kufuneka ndizile ukutya ngaphambi kolu vavanyo lwe-C-peptide?

Ewe, ukuba wenza olu vavanyo lwegazi, ungacelwa ukuba uzile ukutya iiyure ezisi-8 ukuya kwezili-12 (amanzi nje alungile) . Oku sikubiza ngokuba yi-"Fasting". Nangona kunjalo, ngamanye amaxesha, ugqirha wakho unokufuna ukujonga amanqanaba akho e-C-peptide emva kokuba utye into ethile kwaye i-pancreas yakho ivuselelwe. Rhoqo, amanqanaba eglucose egazini nawo ajongwa kunye namanqanaba e-C-peptide.

Kwakhona, ugqirha wakho angakucela ukuba uyeke okwethutyana ukuthatha amayeza athile. Kungoko ke, kungcono ukubuza ugqirha wakho kanye into ekufuneka uyenze ngaphambi kovavanyo.

Ngaba kukho naziphi na iingozi ngolu vavanyo?

Enyanisweni, uvavanyo lwegazi alunangozi ingako. Uvavanyo lomchamo alunangozi ingako. Ngoko ke akukho sizathu sokoyika.

Kuthatha ixesha elingakanani ukufumana iziphumo zovavanyo lwe-C-peptide?

Iziphumo zolu vavanyo, oko kukuthi, ingxelo, zingathabatha naphi na ukusuka kusuku olunye ukuya kwezintlanu ukufika. Oku kunokwahluka ngokuxhomekeke kugqirha nakwilabhoratri.

Ithini ixabiso eliqhelekileyo lovavanyo lwe-C-peptide?

Uluhlu olusempilweni lovavanyo lwe-C-peptide ludla ngokuthathwa njengoluphakathi kwe-0.5 ng/mL ukuya kwi-2.0 ng/mL (okanye ukusuka kwi-0.17 ukuya kwi-0.83 nmol/L) . Nangona kunjalo, khumbula ukuba la maxabiso anokwahluka kancinci kwilabhoratri nganye, ngoko ke kubalulekile ukuthelekisa iziphumo zakho noluhlu oluqhelekileyo kwingxelo yakho.

Zithetha ukuthini iziphumo zovavanyo lwe-C-peptide?

Kulungile, ngoku masibone ukuba amaxabiso akule ngxelo yovavanyo athini.

Ukuba inqanaba le-C-peptide liphantsi (i-C-peptide ephantsi)

Ukuba inqanaba lakho le-C-peptide liphantsi, kunokubakho izizathu ezininzi:

• Xa amanqanaba eswekile egazini lakho ephantsi kwaye ungatyanga kutshanje, kunokuba yinto eqhelekileyo ukuba i-C-peptide ibe phantsi.
• Nangona kunjalo, oku kunokuthetha ukuba umzimba wakho awuvelisi i-insulin eyaneleyo .
• Okanye, ukuba ufaka i-insulin ngaphandle, i-C-peptide inokuncipha (kuba i-C-peptide ayizi ne-insulin enikwa ngaphandle).
• Le meko, ingakumbi ukuba amanqanaba eswekile egazini lakho aphezulu, inokunxulunyaniswa nezi meko zilandelayo zonyango:
• Uhlobo 1 lweswekile : Oku kungenxa yokuba ipancreas yaba bantu ayivelisi i-insulin.
• Uhlobo lwesibini lwesifo seswekile : Oku kwenzeka xa ipancreas ingakwazi ngokupheleleyo ukuvelisa i-insulin.

Enye into enokuthethwa ngamanqanaba aphantsi e-C-peptide kukuba unyango lwesifo seswekile alusebenzi ngokwaneleyo .

Kukho nezinye iimeko apho amanqanaba e-C-peptide nawo ehla njengoko amanqanaba eswekile egazini ehla:

• Isifo sika-Addison : Le yimeko apho amadlala akho e-adrenal engavelisi ngokwaneleyo iihomoni ze-cortisol kunye ne-aldosterone. Oku kudla ngokubangela ukuba iswekile yegazi ibe sezantsi.
• Isifo sesibindi .
• Ukunika i-insulin ngaphandle (inaliti/ukuphefumla) `(i-insulin yangaphandle)` .

Amanqanaba aphezulu e-C-peptide

Ngoku makhe sibone ukuba kuya kwenzeka ntoni ukuba ingxelo ibonisa ukuba inqanaba le-C-peptide yakho liphezulu kunesiqhelo. Oku kunokuthetha ukuba umzimba wakho uvelisa i-insulin eninzi kakhulu . Nazi ezinye zeemeko ezinokubangela oku:

• Isifo sikaCushing: Oku kwenzeka xa umzimba wakho uvelisa i-hormone cortisol eninzi kakhulu.
• Ukumelana ne-insulin : Kule nto, nangona kukho i-insulin emzimbeni, iiseli aziphenduli kakuhle kuyo. Ngoko ke umzimba wenza i-insulin engakumbi.
• Amanqanaba aphantsi e-potassium egazini (i-Hypokalemia) .
• Uhlobo lwesibini lweswekile : Oku kunokwenzeka, ingakumbi kumanqanaba okuqala, xa umzimba uzama ukwenza i-insulin engaphezulu.
• Ithumba le-pancreatic : Umzekelo, i-insulinoma.
• Ukungasebenzi kakuhle kwezintso : Ngenxa yokuba i-C-peptide isuswa emzimbeni ngezintso, xa izintso zingasebenzi kakuhle, amanqanaba e-C-peptide egazini anokunyuka.

Kubalulekile: Ukuba uvavanyo lwe-C-peptide alubonisi ukuba kukho i-C-peptide konke konke, oko kuthetha ukuba kuya kufuneka uyithathe ngaphandle i-insulin. Oku kungenziwa nge-insulin injections okanye i-insulin pump.

Umyalezo Wokuya Ekhaya

Kulungile, ngoko ke ndiyathemba ukuba ngoku uyiqonda ngcono i-C-peptide test ebesithetha ngayo.

• I-C-peptide yinto elinganisa ubungakanani be-insulin eveliswa yimizimba yethu.
• Oku kunceda ukwahlula phakathi kwesifo seswekile sohlobo 1 kunye nesohlobo 2 .
• Ikwasetyenziselwa ukubona ukuba unyango lwesifo seswekile lusebenza njani .
• Oku kunceda nasekuxilongeni ezinye izifo .

Ukuba ugqirha wakho ucele ukuba wenze olu vavanyo lwe-C-peptide, qiniseka ukuba umbuza kanye kanye ukuba wenze ntoni kwaye ungayenzi ntoni ngaphambi kovavanyo. Musa ukoyika nantoni na, olu luvavanyo olulula olunika ulwazi oluxabisekileyo malunga nempilo yakho. Eyona nto ibalulekileyo kukuthetha nogqirha wakho ngayo yonke into kwaye ubuze imibuzo yakho.

I- C-peptide, isifo seswekile, i-insulin, i-pancreas, uvavanyo lwegazi, iihomoni, impilo