Ingaba amalungu akho kunye nobuso bakho buyatshintsha imilo? Masithethe nge-Acromegaly!

Ngaba wakha waziva ngathi iringi ohlala uyinxiba ngoku inamathele emnweni wakho? Okanye ubungakanani bezihlangu zakho, ingakumbi ububanzi, buye baba bukhulu kunesiqhelo? Ngotshintsho oluncinci kangaka, ngaba uvakalelwa kukuba imo yobuso bakho nayo iyatshintsha kancinci kancinci? Usenokungazinaki kakhulu ezi zinto. Kodwa ezi zinokuba ziimpawu zesifo esingaqhelekanga kodwa esixhalabisayo esibizwa ngokuba yi-Acromegaly. Makhe sithethe ngale nto namhlanje.

Ngamafutshane, yintoni i-Acromegaly?

I-Acromegaly yimeko engaqhelekanga kodwa enzulu eyenzeka xa umzimba wakho une -growth hormone (GH) eninzi kakhulu. Le hormone idla ngokuveliswa yi-pituitary gland, i-gland enobukhulu be-pea efumaneka ezantsi kwengqondo yakho. Nangona kunjalo, kwi-acromegaly, le hormone iveliswa kakhulu ngenxa yethumba kwi-pituitary gland okanye kwenye indawo emzimbeni.

I-hormone yokukhula ibalulekile ebantwaneni ukuze bakhule bade baze bakhule. Kodwa xa sele sikhulile, emva kokuba iipleyiti zokukhula emathanjeni ethu zivaliwe, le hormone ayisonyusi ubude bethu. Kodwa imizimba yethu yabantu abadala nayo iyayidinga le hormone. Kukugcina ulwakhiwo olusempilweni lwamathambo ethu, i-cartilage, kunye namalungu omzimba, ukwenza imetabolism ngokufanelekileyo, kunye nokugcina amanqanaba eswekile egazini kwinqanaba elifanelekileyo.

Nangona kunjalo, ukuba i-growth hormone emzimbeni womntu omdala iyanda kakhulu, iingxaki ezininzi zinokuvela, ezinje ngotshintsho olungaqhelekanga kwimilo yamathambo, ukwanda kwamalungu omzimba, kunye nokunyuka kweswekile egazini (i-hyperglycemia).

Yintoni umahluko phakathi kwe-Acromegaly kunye ne-Gigantism?

Zombini ezi meko zibangelwa kukwanda kweHormone yoKhula (GH). Umahluko uphakathi kweqela leminyaka elichaphazelekileyo.

• I-Gigantism: Oku kwenzeka ebantwaneni. Oku kuthetha ukuba ukuba i-GH hormone iyanda ngaphambi kokuba ifikelele ebuntwini, ngaphambi kokuba ii-growth plates zamathambo zivale, abo bantwana bakhula ngokungaqhelekanga. Le yimeko engaqhelekanga nangakumbi kune-acromegaly.
• I-Acromegaly: Oku kwenzeka kubantu abadala. Njengoko bekutshiwo ngaphambili, emva kokuba ii-growth plates zivaliwe, i-GH iyanda, kodwa endaweni yoko imo yamathambo ezandleni, ezinyaweni nasebusweni iyatshintsha ize ibe nkulu.

Ngubani ofumana i-acromegaly? Ixhaphake kangakanani?

I-Acromegaly sisifo esingaqhelekanga. Ngokwezibalo, phakathi kwabantu aba-3 naba-14 kwabayi-100,000 bafunyenwe benale sifo. Nangona sinokukhula nakweyiphi na iminyaka emva kokufikisa, esi sifo sidla ngokufunyaniswa kubantu abaphakathi kweminyaka engama-40 ukuya kwengama-50.

Le meko iwuchaphazela njani umzimba?

Xa i-Growth Hormone (GH) isanda, ixelela isibindi sethu ukuba sivelise enye i-hormone. Ibizwa ngokuba yi-'Insulin-like Growth Factor 1 (IGF-1)'. Le hormone ebizwa ngokuba yi-IGF-1 yenza amathambo ethu kunye nezicubu zikhule, kwaye ilawula iswekile yegazi kunye nee-lipids. Ngoko ke, xa i-GH isanda, i-IGF-1 nayo iyanda kakhulu. Ngenxa yoko, iimeko ezinzima ezifana ne -Type 2 Diabetes, i-High Blood Pressure, kunye ne-Heart Disease zinokwenzeka.

Zithini iimpawu ze-acromegaly?

Iimpawu ze-acromegaly zibonakala kancinci kakhulu, kangangeminyaka emininzi. Ngoko ke kunokuba nzima ukuzibona kwizigaba zokuqala. Usenokubona utshintsho ebusweni bakho kuphela xa ujonge ifoto yakho endala.

Itheyibhile engezantsi ibonisa ngokucacileyo ukuba zeziphi ezi mpawu.

Ukuba unenye okanye ngaphezulu kwezi mpawu, kubaluleke kakhulu ukubona ugqirha wakho ngoko nangoko uze uthethe ngale nto.

Ifunyanwa njani i-acromegaly?

Xa ubona ugqirha, uya kumamela ngenyameko iimpawu zakho, enze uvavanyo lomzimba, aze emva koko acele iimvavanyo ezininzi ukuqinisekisa ukuba unesifo.

• Uvavanyo lwegazi: Olu lolona lubalulekileyo. Lulinganisa amanqanaba e-GH kunye ne-IGF-1 egazini lakho.
• Uvavanyo lweMifanekiso: Ukuba uvavanyo lwegazi luqinisekisa ukuba amanqanaba e-GH aphezulu, i -MRI scan ingayalelwa ukujonga ithumba le-pituitary.

Ukuba isifo siqinisekisiwe, kunokwenziwa olunye uvavanyo ukuze kubonwe ukuba sichaphazele amanye amalungu omzimba.

• I- echocardiogram yokujonga ukusebenza kwentliziyo.
• Uphononongo lokulala ukuze kubonwe ukuba uyafuthaniseka na ngelixa ulele.
• I-Colonoscopy ukujonga impilo ye-colon.
• I -X-ray okanye i-DEXA scan ukujonga impilo yamathambo.

Ziziphi iindlela zonyango lwe-acromegaly?

Kukho iindlela ezahlukeneyo zonyango lwe-acromegaly. Ugqirha wakho uya kugqiba ukuba loluphi unyango olulungele wena ngokusekwe kwimeko yakho, ubungakanani kunye nendawo yethumba.

1. Utyando: Olu lolona nyango luphambili kubantu abaninzi. Inkqubo eqhelekileyo ibizwa ngokuba yiTranssphenoidal Surgery . Oku kuquka ukususa ithumba le-pituitary gland ngempumlo. Ukuba ithumba lisusiwe ngokupheleleyo, kukho ithuba elihle lokuphiliswa ngokupheleleyo.

2. Amayeza: Ukuba utyando alukwazi ukususa ngokupheleleyo ithumba, okanye ukuba kuyimfuneko ukunciphisa ithumba ngaphambi kotyando, kusetyenziswa amayeza. La mayeza alawula amanqanaba e-GH emzimbeni. Abanye abantu banokufuna ukuthatha amayeza ixesha elide.

3. Unyango lweMisebe: Olu nyango lusetyenziselwa ukutshabalalisa naziphi na iindawo eziseleyo zethumba xa utyando kunye namayeza zingenakukwazi ukulawula isifo.

Zeziphi iingxaki ezinokwenzeka ukuba azinyangwa?

Ukuba ayinyangwa, i-acromegaly inokukhokelela kwiingxaki zempilo ezinzulu ngokuhamba kwexesha. Le yeyona nto iyingozi kakhulu kwesi sifo.

• Uhlobo lwesibini lwesifo seswekile
• Uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi oluphezulu)
• Isifo sentliziyo, ngakumbi i-cardiomyopathy
• Isifo samathambo
• Iipolyps zekholoni - Ezi zinokuguquka zibe ngumhlaza kamva.
• Ukungasebenzi kakuhle kwamalungu omzimba

Kungoko ke, kubaluleke kakhulu ukubona ugqirha ngokukhawuleza ukuba uneempawu kwaye ulandele unyango olumiselweyo ukuba isifo sifunyenwe. Ukuba amanqanaba e-GH alawulwa ngonyango, umngcipheko wezi ngxaki unokuncipha kakhulu.