Ngaba uvuka kusasa unentlungu eqinileyo, evuvukileyo, nenganyamezelekiyo kumalungu akho? Ngaba amalungu akho afana namadolo neengqiniba zakho abuhlungu? Mhlawumbi ugqirha wakho ukuxelele ukuba uqale uhlobo lonyango olubizwa ngokuba yi-'DMARDs'. Ngaba waziva usoyika kancinci xa usiva elo gama? Ngaba wacinga ukuba, 'Luhlobo luni lonyango olu?'? Ungakhathazeki. Namhlanje, siza kuthetha ngezi DMARD ngendlela elula kakhulu onokuyiqonda.
Zithini ii-DMARD ngokulula?
Khawucinge ukuba kukho umlindi okrelekrele kakhulu emzimbeni wethu. Lo mlindi simbiza ngokuba yinkqubo yomzimba yokuzikhusela . Umsebenzi wakhe ophambili kukusikhusela kwizifo ngokulwa neentsholongwane ezibangela izifo (ezifana neentsholongwane kunye neebhaktheriya) ezingena emzimbeni zivela ngaphandle.
Kodwa ngamanye amaxesha, kunqabile kakhulu, lo mlindi wethu wenza impazamo encinci. Ucinga ukuba iiseli eziphilileyo emzimbeni wakhe, ingakumbi kwiindawo ezifana namalungu ethu, zilutshaba aze aqale ukuzihlasela. Kufana nokuphosa amatye endlwini yakhe. Le meko siyibiza ngokuba sisifo sokuzikhusela komzimba .
Kulapho ke kungena khona udidi lwamayeza abizwa ngokuba yi-DMARD. I-DMARD imele 'Amayeza Okuguqula Izifo'. Eli gama lisenokuvakala lide kancinci, kodwa eneneni lilula kakhulu. Oko kwenziwa ngala mayeza kukuthomalalisa nokulawula inkqubo yomzimba yokuzikhusela, esebenza kakhulu kwaye ihlasela umzimba wayo.
Kukho iingenelo eziphambili ezininzi ezibonelelwa leli yeza emzimbeni wethu:
- Inciphisa ukudumba kunye nokudumba kwamalungu.
- Ikunceda ukulawula intlungu oyivayo.
- Iyanciphisa ukusasazeka okanye ubukhali besifo.
- Inciphisa okanye ithintela umonakalo ongunaphakade kumalungu namathambo.
- Ikunceda ukugcina amalungu akho esebenza kakuhle kwaye wenze imisebenzi yakho yemihla ngemihla.
Zeziphi izifo ezisetyenziselwa i-DMARD?
Oogqirha basebenzisa la mayeza, abizwa ngokuba yi-DMARD, ikakhulu ukulawula ukudumba okubangelwa zizifo ezizikhuselayo emzimbeni. Nazi imizekelo embalwa:
- Irheumatoid arthritis
- I-Ankylosing spondylitis
- Isifo samathambo se-Psoriatic
- I-Lupus
- Isifo samathambo esibangelwa yi-Juvenile idiopathic
- I-Scleroderma
- Isifo sokugubhuka
- Isifo sikaSjögren
- I-Myositis
- I-rheumatoid vasculitis
- Isifo samathumbu esidumbileyo - umzekelo, isifo sikaCrohn
Ukongeza, ii-DMARD zingasetyenziselwa ukunyanga ezinye iintlobo ezingaqhelekanga zomhlaza.
Ziziphi iintlobo eziphambili ze-DMARD?
Ii-DMARD zingahlulwahlulwa zibe ngamaqela amabini aphambili. Indlela ezisebenza ngayo kunye nendlela ezisetyenziswa ngayo yahlukile kancinci.
| Uhlobo lwe-DMARD | Ingcaciso elula | Imizekelo esetyenziswa rhoqo |
|---|---|---|
| IiDMARD zemveli | La mayeza achaphazela yonke inkqubo yomzimba yokuzikhusela, enciphisa ukusebenza kwayo. Olu hlobo lwamayeza ludla ngokuba lolona luqalayo. Adla ngokuza ngohlobo lweepilisi ezithathwa ngomlomo. |
|
| I-Biologics | La mayeza aluhlobo olutsha noluphucukileyo. Afana 'nomjukujelwa okhokelwayo'. Ajolise kwaye ahlasele kuphela inxalenye ethile yeeseli zenkqubo yomzimba yokuzikhusela ezibangela esi sifo, ngaphandle kokuchaphazela yonke inkqubo. Adla ngokunikezelwa njenge-IV infusion okanye njenge-subcutaneous injection. |
Ugqirha wakho uza kugqiba ukuba loluphi uhlobo kwezi zimbini aza kukunika lona, okanye ukuba uza kukunika zombini na, ngokusekwe kwimeko yakho, ubukhali bayo, kunye nokuba loluphi olusebenza kakuhle emzimbeni wakho.
Ibali eloyikwa ngumntu wonke: Ngaba kukho naziphi na iziphumo ebezingalindelekanga?
Njengalo naliphi na iyeza, ii-DMARD zinokubangela ezinye iziphumo ebezingalindelekanga. Kodwa ungoyiki olu luhlu. Asinguye wonke umntu oza kufumana zonke ezi ziphumo ebezingalindelekanga. Ugqirha wakho uza kukuphatha ngendlela eya kunciphisa lo mngcipheko.
| Uhlobo lwesiphumo esibi | Inkcazo kunye noko kufuneka ukwazi |
|---|---|
| Iziphumo ebezingalindelekanga ezinokwenzeka ziqhelekile kuzo zombini iintlobo ze-DMARD | |
| Umngcipheko ophezulu wosulelo | Ngenxa yokuba la mayeza acinezela inkqubo yomzimba yokuzikhusela, unokufumana lula izifo ezifana nomkhuhlane kunye neflu (umngcipheko uphezulu kancinci nge-biologics). Ngoko ke kubalulekile ukuhlala kude nabantu abagulayo kwiindawo ezixineneyo. |
| Ukuncipha kweeseli zegazi | Inani leeseli ezimhlophe zegazi (i-leukopenia), iiseli ezibomvu zegazi (i-anemia), kunye nenani leeplatelet (i-thrombocytopenia) zinokwehla. Yiyo loo nto ugqirha ehlala esenza uvavanyo lwegazi. |
| Ii-enzymes zesibindi eziphakamileyo | Ezinye ii-DMARD zinokuchaphazela isibindi. Oku kujongwa nangovavanyo lwegazi. |
| Iziphumo ebezingalindelekanga ezinokuthi zenzeke kwi-DMARD yendabuko | |
| Iingxaki zokugaya ukutya | Ukuphelelwa ngumdla wokutya, isicaphucaphu, ukuhlanza, iintlungu zesisu, kunye norhudo lunokwenzeka. |
| Ukuqhambuka kwesikhumba | Abanye abantu banokuba nerhashalala eluswini. |
| Iziphumo ebezingalindelekanga ezinokubakho kwi-biologics | |
| Ukuphinda kuvele usulelo oludala | Ukuba ukhe waba nezifo ezifana nesifo sephepha, i-herpes, okanye i-hepatitis ngaphambili, la mayeza angazivuselela. Ngoko ke, ugqirha wakho uza kujonga oku ngaphambi kokuba aqalise amayeza. |
| Iimpendulo kwindawo yokujova | Kusenokubakho ukubomvu, ukudumba, okanye iintlungu kwindawo yokutofa. |
Eyona nto ibalulekileyo kukwazisa ugqirha wakho ngokukhawuleza ukuba ufumanisa naziphi na iimpawu ezintsha okanye iziphumo ebezingalindelekanga.
Kuthatha ixesha elingakanani ukuba eli yeza lisebenze?
Lo ngumbuzo obaluleke kakhulu. Ii-DMARD aziloyeza olithathayo kwangoko nje ukuba ulithathe, njengeyeza lokuthomalalisa iintlungu. La mayeza athatha ixesha ukuba angene emzimbeni, alawule inkqubo yomzimba yokuzikhusela, aze abonise iziphumo.
- IiDMARD zemveli zingathatha inyanga okanye ngaphezulu ukusebenza.
- Iibhayoloji zihlala ziqala ukusebenza kwiiveki ezimbalwa .
Ungakhathazeki ukuba intlungu ayipheli kwangoko xa uqala ukuthatha eli yeza. Kuthatha ixesha ukubona iziphumo, ngoko ke kubalulekile ukuba nomonde. Ugqirha wakho uza kukunika amanye amayeza okunceda ukulawula intlungu okwangoku.
Ndifanele ndiphinde ndimbone ugqirha kwakhona?
Wakuba uqalile ukusebenzisa i-DMARD, ugqirha wakho uza kukujonga rhoqo. Ngoko ke kubalulekile ukuya ekliniki ngexesha. Uya kuhlala ufumana oku kulandelayo:
- Uvavanyo lwegazi oluqhelekileyo: Uza kucelwa ukuba wenze uvavanyo lwegazi oluqhelekileyo ukujonga ukuba amayeza asebenza kakuhle na kwaye ukuba kukho naziphi na iziphumo ebezingalindelekanga (ukubalwa kweeseli zegazi, ukusebenza kwesibindi).
- Ukuhlolwa kwezifo: Uza kuhlolwa rhoqo ukuba awunazo na izifo, ingakumbi ukuba usebenzisa i-biologics.
- Uvavanyo olufana ne-X-reyi: Uvavanyo olufana ne-X-reyi lunokwenziwa rhoqo ukujonga umonakalo kumalungu.
Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezintsha, uzive ngathi iyeza alisebenzi, okanye ukuba iimpawu zakho ziya zisiba mandundu, thetha nogqirha wakho ngoko nangoko, ngaphandle kokulinda idinga elilandelayo leklinikhi.
Nangona ii-DMARD zinokuvakala ngathi ludidi lwamayeza othusayo nolunzima, zinokukunceda ukulawula isifo sakho, zithintele umonakalo wamalungu, kwaye zikuncede uphile ubomi obuqhelekileyo. Ugqirha wakho uza kukhetha indibaniselwano efanelekileyo yamayeza. Ngoko ke ungoyiki ukubuza ugqirha wakho nayiphi na imibuzo onokuba nayo.
Umyalezo Wokuya Ekhaya
- Ii-DMARD azizizo iintlungu. Ziiziyobisi ezilawula inkqubo yomzimba yokuzikhusela esebenza kakhulu, nto leyo ebangela isifo sakho.
- Kungathatha iiveki ezininzi okanye inyanga ukuba la mayeza asebenze, ngoko ke umonde ubaluleke kakhulu.
- Nangona iziphumo ebezingalindelekanga zinokwenzeka, ugqirha wakho uza kukujonga ngokusondeleyo ngovavanyo lwegazi rhoqo.
- Ungaze uyeke ukuthatha amayeza okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha.
- Ukuba ubonakalisa iimpawu ezingaqhelekanga (umkhuhlane, ukukhwehlela, olunye usulelo), yazisa ugqirha wakho ngoko nangoko.
- Ukuba zisetyenziswa ngokuchanekileyo, ii-DMARD zinokuphucula kakhulu umgangatho wobomi bakho.
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