Ngaba wakha wazibuza ukuba umzimba wakho ugcina njani amanqanaba eswekile egazini lakho elungelelene ngokugqibeleleyo? Umdlali ophambili kule nkqubo yinto ebizwa ngokuba yiglucagon. Cinga ngayo njengeqhawe elincinci ngaphakathi kwenkqubo yakho, elisebenza ngokungakhathali ukuqinisekisa ukuba iswekile yakho egazini ayiweli phantsi kakhulu. Namhlanje, siza kuhlola indlela esebenza ngayo iglucagon, ngokucacileyo nangokulula apha eNirogi Lanka.
Yintoni iGlucagon?
Ngamafutshane, i-glucagon yi-hormone yendalo eveliswa ngumzimba wakho . Ngokukodwa, yenziwa ziiseli ze-alpha ezikwi-pancreas yakho. Umzimba wakho ukhupha i-glucagon nanini na xa amanqanaba eglucose egazini lakho ehla—njengaxa uzila ukutya ixesha elide, uzilolonga kakhulu, okanye emva kokutya isidlo esineeproteni ezininzi.
Cinga ngeglucose njengomthombo oyintloko wamafutha emzimbeni wakho, owufumana kwiicarbohydrates ekutyeni okutyayo. Njengepetroli yemoto, le glucose inika amandla abalulekileyo afunekayo ukuze amalungu akho, izihlunu, kunye nenkqubo yemithambo-luvo isebenze. Umzimba wakho ugcina ibhalansi entsonkothileyo nethambileyo yokugcina la manqanaba eswekile ekwinqanaba elifanelekileyo; ukuba aya phezulu kakhulu okanye asezantsi kakhulu, kunokukhokelela kwiingxaki ezahlukeneyo zempilo.
Iinaliti zeGlucagon kunye neeSpray zempumlo
Ukongeza kwi-glucagon eyenziwa ngumzimba wakho, kukho iintlobo zokwenziwa ezikhoyo njengezitofu okanye izitshizi zeempumlo ezomileyo. Usenokuba uzibonile ezi zisetyenziswa, ingakumbi ngabantu abanesifo seswekile sohlobo loku-1 , njengonyango olungxamisekileyo lwe-hypoglycemia enzima (iswekile yegazi ephantsi kakhulu). Xa inikwa, le glucagon isebenza ngokukhuthaza isibindi sakho ukuba sikhuphe i-glucose egciniweyo egazini lakho, nto leyo ebonelela ngempumelelo 'ngokunyusa' amanqanaba eswekile yakho ngokusindisa ubomi.
IGlucagon Ichaphazela Njani Umzimba Wakho?
Xa ipancreas yakho isebenza ngokuchanekileyo, ilawula ngononophelo iglucose egazini lakho isebenzisa iihomoni ezimbini eziphambili: iglucagon kunye ne-insulin . Xa amanqanaba eswekile egazini lakho eqala ukwehla kakhulu (i-hypoglycemia), ipancreas yakho ikhupha iglucagon engakumbi ukuze ibuyisele amanqanaba kwakhona ngeendlela ezahlukeneyo:
- Okokuqala, i-glucagon iya esibindini sakho ize iguqule i-glucose egciniweyo—eyaziwa ngokuba yi -glycogen —ibe yindlela esebenzisekayo, ethi emva koko isibindi siyikhuphele egazini lakho.
- Okwesibini, i-glucagon ixelela isibindi sakho ukuba siyeke ukugcina i-glucose, nto leyo eqinisekisa ukuba ininzi into ekhoyo egazini lakho.
- Okwesithathu, i-glucagon inceda umzimba wakho ukuba uvelise i-glucose entsha evela kweminye imithombo, njengee -amino acids .
Khumbula, oku kufana ne-seesaw: xa iswekile yegazi iphantsi, i-glucagon iyasebenza; xa iswekile yegazi iphezulu, i-insulin iyakhokela!
Ziziphi iimeko ezichaphazela umsebenzi weGlucagon?
Ukuba umzimba wakho unengxaki yokulawula i-glucagon ngokufanelekileyo, oko kunokukhokelela kwimingeni yempilo.
Ukuba unesifo seswekile, umzimba wakho usenokusokola ukukhupha i-glucagon eyaneleyo xa iswekile yegazi isihla. Oku kukubeka kwindawo engaqhelekanga.umngcipheko ophezulu we-hypoglycemia exhaphakileyo okanye enzima, ingakumbi ukuba uthatha i-insulin okanye amayeza athile afana ne-sulfonylureas.
Kwabanye abantu abanesifo seswekile sohlobo lwesibini, amanqanaba e-glucagon anokuba phezulu kunesiqhelo, nto leyo enokubangela ukuba iswekile yegazi inyuke.
Nangona iingxaki ngemveliso ye-glucagon ngaphandle kwesifo seswekile zinqabile, zinokwenzeka ngenxa yezi zinto zilandelayo:
- I-Pancreatitis: Ukuba ukudumba okungapheliyo kwe-pancreas kubangela isifo seswekile, unokujongana nokungabikho kwe-glucagon, nto leyo eyandisa umngcipheko wakho wokuba neswekile ephantsi egazini.
- I-Glucagonoma: Ithumba elingaqhelekanga kakhulu kwi-pancreas elivelisa i-glucagon eninzi, nto leyo ekhokelela kwiswekile ephezulu egazini, amaqhakuva athile eluswini, kunye nokwehla kobunzima.
- I-Multiple Endocrine Neoplasia (MEN): Imeko engaqhelekanga yemfuza apho amadlala amaninzi kwinkqubo yakho ye-endocrine evelisa iithumba, ezinokuquka i-pancreas.
- Utyando lwePancreatectomy: Ukuba inxalenye okanye yonke ipancreas yakho isusiwe ngotyando, unokulahlekelwa ziiseli ezivelisa iglucagon kunye ne-insulin.
Iimpawu zeengxaki ezinxulumene neGlucagon
Njengoko kuxoxiwe, ukungaqhelekanga kwi-glucagon kunokukhokelela kwi-hypoglycemia (iswekile ephantsi yegazi) okanye i-hyperglycemia (iswekile ephezulu yegazi). Nantsi indlela onokuzibona ngayo ezi mpawu.
Iimpawu zeHypoglycemia (Iswekile Ephantsi Egazini)
Ukuba wena okanye umntu omthandayo unesifo seswekile, kubalulekile ukuqaphela iimpawu zokwehla kweswekile egazini. Usenokuziva uqhaqhazela ngequbuliso, ubila, okanye unesizungu, kwaye ube nobunzima bokuthetha okanye ukugxila. Oku kungaba luphawu lweswekile ephantsi egazini.
Iimpawu eziqhelekileyo ziquka:
- Ukungcangcazela okanye ukungcangcazela
- Ukubila nokuziva ubanda
- Isiyezi okanye ukuba nentloko ebuhlungu
- Ukubetha kwentliziyo ngokukhawuleza
- Indlala ngequbuliso
- Ukudideka okanye ubunzima bokugxila
Kubalulekile: Ukuba ufumana ezi mpawu, kubalulekile ukuba utye into equlethe iswekile okanye iicarbohydrates ngoko nangoko . Oku kunceda ukubuyisela amanqanaba eswekile egazini lakho. Ukuba oku kwenzeka rhoqo, kufuneka udibane nogqirha wakho ngokukhawuleza.
Iimpawu ze-High Blood Sugar (i-Hyperglycemia)
Iswekile ephezulu egazini (i-hyperglycemia) idla ngokubangelwa kukungabikho kwe-insulin, kunokuba ibe yingxaki ephambili nge-glucagon. Nangona kunjalo, iingxaki ezingaqhelekanga ezinxulumene ne-glucagon zinokubangela iswekile ephezulu egazini. Iimpawu zokuqala ziquka:
- Ukomelela kakhulu kunye/okanye indlala engapheliyo
- Umbono ofipheleyo
- Ukuchama rhoqo
- Intloko ebuhlungu
Ukuba uhlangabezana nezi mpawu, kubaluleke kakhulu ukubonana nengcali yezempilo.
Zeziphi iimvavanyo ezisetyenziswa ukujonga amanqanaba eGlucagon?
Ukuba ubonakalisa iimpawu ezithile, ugqirha wakho unokuyalela uvavanyo lwegazi ukujonga amanqanaba akho e-glucagon. Ngexesha lale nkqubo, ugqirha okanye umongikazi uza kuqokelela isampuli yegazi emthanjeni esebenzisa inaliti, ize ithunyelwe kwilebhu ukuze ihlolwe.
Zithini iiGlucagon eziqhelekileyo?
Ngokwesiqhelo, uluhlu oluqhelekileyo lweglucagon egazini lakho luphakathi kwama -picogram angama-50 kunye nama-100 kwi-milliliter nganye (pg/mL) . I-picogram yi-trillionth enye yegram—umlinganiselo wokwenyani!
Khumbula ukuba la manqanaba okubhekisela anokwahluka kancinci phakathi kweelabhoratri ezahlukeneyo. Ukongeza, iziphumo zakho zinokuchaphazeleka bubude bexesha ozila ukutya kunye namanqanaba akho eswekile egazini ngexesha lovavanyo. Ke ngoko, soloko uthelekisa iziphumo zakho kunye namanqanaba okubhekisela anikezelweyo kwingxelo yakho yelabhoratri ethile . Ukuba unemibuzo, yixoxe nogqirha wakho eNirogi Lanka.
Ufanele uye nini kugqirha malunga namanqanaba akho eGlucagon?
Ukuba unesifo seswekile kwaye uhlala ufumana iziqendu zeswekile ephantsi okanye ephezulu egazini, kubalulekile ukubonana nogqirha wakho. Nangona amanqanaba eglucagon engajongwa rhoqo kubo bonke abantu abanesifo seswekile, isicwangciso sakho sokulawula isifo seswekile sinokufuna uhlengahlengiso ukuze kuncitshiswe olu tshintsho.
Nangona ezinye iingxaki ezinxulumene neglucagon zinqabile, ukuba uhlangabezana neempawu, ukufumana unobangela kubalulekile. Soloko ubeka phambili ukubhukisha idinga nomboneleli wakho wezempilo.
Yintoni umahluko phakathi kweGlucagon kunye neGlycogen?
Ezi zimbini zahlukile. I-Glycogen luhlobo olugciniweyo lwe-glucose (iswekile). Umzimba wethu ngokuyintloko ugcina i-glycogen kwisibindi nakwimisipha.
I-Glucagon yi-hormone. Isebenza njengesixhobo sokunika imiqondiso, ixelela isibindi ukuba siguqule i-glycogen egciniweyo ibe yi-glucose, ize ikhutshwe iye egazini ukuze inike umzimba wakho amandla.
Kwenzeka ntoni kwiGlucagon xa uzila ukutya?
Xa uzila ukutya, i-glucagon ibalulekile ekuthinteleni ukuba iswekile yakho yegazi ingabi phantsi kakhulu, kuba umzimba wakho awufumani iswekile ekutyeni.
Ngexesha lokuzila ukutya ixesha elide, i-glucagon ivuselela ukuveliswa kwe-glucose kwimithombo engeyiyo i-carbohydrate, efana nee-lipids, ii-amino acids, kunye neeproteni. Le nkqubo ibizwa ngokuba yi-gluconeogenesis .
Umyalezo Wokugqibela Wokuya Ekhaya
Njengoko ubona, i-glucagon yi-hormone ebalulekileyo esebenza ngasese ukugcina amanqanaba eswekile egazini esempilweni. Ukuba awunaso isifo seswekile, iingxaki ze-glucagon aziqhelekanga.
Nangona kunjalo, ukuba uhlala ufumana iimpawu zeswekile ephantsi okanye ephezulu egazini, nceda udibane nogqirha wakho. Banokuchonga unobangela oyintloko baze bakunike unyango olufunekayo. Ukubeka impilo yakho phambili lelona nyathelo libalulekileyo onokulithatha.
👩🏽⚕️ Imibuzo Ebuzwa Rhoqo (Ii-FAQ)
💬 Ingaba i-glucagon liyeza elifana ne-insulin elihlisa iswekile egazini?
Hayi, kuchasene ngokupheleleyo! I-Glucagon yi-hormone efumaneka emzimbeni wakho esebenza njenge-insulin. Nangona i-insulin yenzelwe ukunciphisa iswekile egazini lakho, i-glucagon isebenza njengendlela yokuhlangula; xa iswekile yegazi lakho isihla iye kumanqanaba aphantsi kakhulu (hypoglycemia), i-glucagon ixelela isibindi sakho ukuba sikhuphe i-glucose egciniweyo (glycogen) egazini lakho, nto leyo ebuyisela amanqanaba akho kwinqanaba elikhuselekileyo.
💬 Kutheni i-glucagon igcinwa njengonyango olungxamisekileyo?
Ukuba umntu onesifo seswekile ufumana i-hypoglycemia enzima—ekhokelela ekudidekeni okanye ekulahlekelweni zingqondo—akanakukwazi ukuginya iswekile ngokukhuselekileyo, njengoko enokuminxeka. Kule mizuzu ibalulekileyo, inaliti yeglucagon (okanye ipeni) efakwa ethangeni okanye engalweni engaphandle inokunyusa amanqanaba eswekile egazini kwimizuzu embalwa, incede isigulana ukuba siphinde siqonde. Ukuba oku kuyenzeka, soloko unxibelelana neenkonzo zongxamiseko (911) emva nje kokuthatha.
💬 Ngaba kulula ukufaka inaliti yeglucagon ekhaya?
Ewe. Njenge-EpiPen esetyenziselwa i-allergies ezinzima, ezi zixhobo zongxamiseko zenzelwe amalungu osapho okanye abanakekeli ukuba bazisebenzise lula ekhaya. Ezinye iindawo zikwabonelela ngee-spray zeempumlo (ezifana neBaqsimi). Ukuba umntu ohlala ekhaya usebenzisa i-insulin, ukugcina isixhobo songxamiseko se-glucagon sifumaneka lula yindlela ebalulekileyo yokhuseleko enokusindisa ubomi. Soloko unxibelelana nomboneleli wakho wezempilo waseNirogi Lanka malunga nokusetyenziswa ngokufanelekileyo.
Amagama angundoqo: i-glucagon, iswekile yegazi, i-hypoglycemia, i-hyperglycemia, isifo seswekile, i-pancreas, i-hormone
