Ingaba unamanqanaba aphezulu e-hormone prolactin emzimbeni wakho? Masithethe nge-hyperprolactinemia!

Ngaba wakha wazibuza ukuba kungakanani okunokwenzeka ngotshintsho oluncinci kwezinye iihomoni emzimbeni wakho? Leyo yimeko esiza kuthetha ngayo namhlanje, ebizwa ngokuba yi-hyperprolactinemia. Ngamafutshane, oku kwenzeka xa igazi lakho linehomoni eninzi ebizwa ngokuba yi-prolactin. Le homoni inoxanduva lokukhula kwamabele kunye nokuveliswa kobisi. Le meko ayisongeli ubomi, kodwa ngamanye amaxesha inokubangela iingxaki ezifana nokungazali kwaye iphazamise amandla akho okuphila ubomi obuqhelekileyo. Kodwa iindaba ezimnandi zezokuba kukho unyango lwayo.

Ixhaphake kangakanani le meko?

Enyanisweni, le meko ibizwa ngokuba yi-hyperprolactinemia ayixhaphakanga kangako. Ichaphazela ngaphantsi kwe-1% yoluntu ngokubanzi. Nangona kunjalo, abafazi banamathuba amaninzi okufumana le meko kunamadoda.

Zithini iimpawu zoku?

Khumbula, abanye abantu banokuba ne-hyperprolactinemia kodwa bangabonakalisi zimpawu, okanye iimpawu zinokuba zincinci kakhulu. Nangona kunjalo, kukho iimpawu ezimbalwa eziqhelekileyo ezinokwenzeka kule meko, nokuba umntu ungubani.

Iimpawu eziqhelekileyo ezichaphazela wonke umntu

Ezi zinokwenzeka nakubani na, kungakhathaliseki ukuba ungubani na:

• Ubunzima bokufumana abantwana (ukungazali) : Le yeyona ngxaki iphambili.
• Umoya wokuthanda izinto ezingafanelekanga : Oku kuthetha ukuncipha komdla kwizenzo zesondo.
• Ukuncipha koxinano lwamathambo (i-osteopenia) : Oku kunokubangela ukuba amathambo abe buthathaka ngokuhamba kwexesha.
• Ukuphuma kobisi oluvela kwiingono xa ungakhulelwanga okanye ungancancisi (`galactorrhea`) : Oku kusenokuvakala kungaqhelekanga, kodwa kukwaluphawu.

Iimpawu ezithile kubafazi

Kwabasetyhini, ukongeza kwezi mpawu ziqhelekileyo, ezinye iimpawu ezithile zinokwenzeka:

• Utshintsho kumjikelo wokuya exesheni olungahambelani nokuya exesheni (ukuphela kokuya exesheni ngenyanga) : Oku kuthetha ukuba ukuya exesheni kuba yinto engaqhelekanga okanye kuyeke ngokupheleleyo. Usenokungabi nayo inyanga.
• Intlungu ngexesha lokwabelana ngesondo ngenxa yokoma kwelungu lobufazi : Oku kukwayinto eyenza abafazi abaninzi bangakhululeki.

Iimpawu ezithile kumadoda

Le meko ichaphazela amadoda ngeendlela ezahlukeneyo. Nazi ezinye zeempawu eziqhelekileyo abanokuzibona:

• Ukungasebenzi kakuhle kwe-Erectile Dysfunction (ED) : Oku kuthetha ubunzima bokufumana i-erection.
• Ukwehla kwamanqanaba e-testosterone : Le yi-hormone ebalulekileyo emzimbeni wendoda.
• Ukwandiswa kwamabele (`gynecomastia`) : Ukukhula kwamabele endoda ukuze afane nawomfazi.

Kutheni oku kusenzeka? Zithini izizathu?

Kulungile, ngoku makhe sijonge ukuba kutheni amanqanaba eprolactin enyuka ngolu hlobo. Kunokubakho izizathu ezahlukeneyo.

• I-Prolactinoma: Esi sesona sizathu siphambili. `(Prolactinoma)` sisimila esingengomhlaza (esingenobungozi) (`adenoma`) esikhula kwi`(i-pituitary gland)` engqondweni yakho. Esi simila sibangela ukuba i-hormone prolactin iveliswe ngokugqithisileyo.
• Ezinye iithumba zepituitary : Ukongeza kwiprolactinoma, ezinye iithumba ezinkulu kwi-pituitary gland okanye kufutshane nazo zinokubangela amanqanaba aphezulu e-prolactin. Oku kwenzeka kuba ithumba lithintela ukukhululwa kwekhemikhali ebizwa ngokuba yi-dopamine kwi-pituitary gland. I-Dopamine yi-hormone elawula ukuveliswa kwe-prolactin.
• Amayeza athile : Ikhemikhali ebizwa ngokuba yi-dopamine inciphisa ukuveliswa kwe-prolactin. Ngoko ke, naliphi na iyeza elichaphazela ukuveliswa kwe-dopamine linokunyusa amanqanaba akho e-prolactin. Amanye ala mayeza aquka:
• Iipilisi zokulawula inzala
• Amanye amayeza okugula ngengqondo, afana neRisperidone kunye neHaloperidol
• Amayeza oxinzelelo lwegazi oluphezulu, afana ne-methyldopa kunye ne-verapamil
• Amayeza okunyanga isitshiso sentliziyo kunye nesifo se-gastroesophageal reflux (GERD) (umz. ii-antihistamines ze-H2)
• Amayeza okudakumba, anjenge-tricyclic antidepressants kunye ne-SSRIs
• Amayeza eempawu zokuya exesheni, njengonyango lwe-estrogen
• Amayeza okunyanga isicaphucaphu nokuhlanza (i-antiemetics)
• Izithomalalisi zentlungu ezinee-opioid

Kubalulekile : Ngokuqinisekileyo kufuneka uthethe nogqirha wakho ngaphambi kokuba uyeke naliphi na iyeza olisebenzisayo. Amanqanaba eprolactin adla ngokubuyela kwisiqhelo kwiintsuku ezintathu ukuya kwezine emva kokuyeka iyeza.

• Ezinye iimeko zempilo : Nokuba ingenayo i-prolactinoma, ezinye iimeko zinokubangela amanqanaba aphezulu e-prolactin. Ezi meko ziquka:
• Ukulimala eludongeni lwesifuba (umz., ukwaphuka kwembambo)
• Isifo sezintso esingapheliyo
• Isifo sesibindi esingapheliyo
• Isifo sikaCushing
• I-Hypothyroidism (i-thyroid engasebenzi kakuhle)
• I-Herpes zoster (ii-shingles), ingakumbi ukuba kuvela amadyungudyungu/amabala esifubeni
• I-Polycystic ovary syndrome (i-PCOS)

Kuthekani ukuba awukwazi ukufumana isizathu?

Ngamanye amaxesha oogqirha abakwazi ukufumana unobangela woku. Kwimeko enjalo, ibizwa ngokuba yi-"idiopathic hyperprolactinemia." Oku kudla ngokuphela ngaphandle konyango kwiinyanga ezimbalwa.

Zithini izinto ezibangela umngcipheko?

Eyona nto ibalulekileyo yomngcipheko we-hyperprolactinemia yimeko ebizwa ngokuba yi-Multiple endocrine neoplasia (MEN) type 1 (MEN1). I-MEN1 yimeko yelifa enokukhokelela ekuphuhlisweni kwe-prolactinoma.

Ukuba kukho umntu kusapho lwakho (umnakwenu, udadewenu, umzali) one-'MEN1', licebo elihle ukwenza uvavanyo lwemfuza. Oku kunokunceda ekuchongeni i-'(Prolactinoma)' kwangethuba.

Uyibona njani le nto kanye kanye?

Ukuba unezi mpawu, into yokuqala ugqirha aza kuyenza kukwenza uvavanyo lwegazi lwe-prolactin (PRL).

Ukuba iziphumo ziqinisekisa ukuba une-hyperprolactinemia, inyathelo elilandelayo kukufumana unobangela. Ugqirha wakho unokuyalela uvavanyo olongezelelweyo lwegazi kunye novavanyo lomfanekiso (olufana ne-MRI scan).

Zithini iindlela zonyango?

Unyango luxhomekeke kwisizathu. Ukuba amanqanaba akho e-prolactin aphezulu kodwa iimpawu zakho zincinci, usenokungaludingi unyango.

Unyango lweprolactinoma

Le yeyona nto ixhaphakileyo. Ngoko ke kukho iindlela ezahlukeneyo zokuyinyanga:

• Amayeza : Ii-dopamine agonists zilawula amanqanaba akho e-prolactin. La mayeza asebenza kakhulu ekunciphiseni iithumba ze-prolactinoma. Olu lolona nyango lusetyenziswa kakhulu kwi-prolactinoma.
• Utyando : Ukuba i-prolactinoma ayinciphi ngamayeza, kunokufuneka utyando ukuze isuswe.
• Unyango lwemitha : Olu lukhetho lwesithathu olungasetyenziswa rhoqo. Lusetyenziswa kuphela xa ezinye iindlela zingaphumeleli.

Ukuba kungenxa yeyeza...

Ukuba kufunyaniswe ukuba amanqanaba akho e-prolactin aphezulu ngenxa yamayeza owasebenzisayo, ugqirha wakho uya kukunika amanye amayeza angayi kuba nefuthe kangako kumanqanaba akho e-prolactin.

Zithini amathuba okuphila kwakhona?

I-Hyperprolactinemia idla ngokuba ngcono kuba unobangela wayo unyangwa ngempumelelo.

Nangona oku kungasongeli ubomi, kunokubangela iingxaki ezifana nokungazali kunye nomjikelo wokuya exesheni ongaqhelekanga, ngoko ke kubaluleke kakhulu ukufuna unyango ukuba unale meko.

Imibuzo omele uyibuze ugqirha wakho

Ukuba une-hyperprolactinemia, kunokuba luncedo ukubuza ugqirha wakho le mibuzo:

• Kutheni oku kwenzeke kum?
• Zeziphi iimvavanyo ekufuneka ndizenze?
• Ziziphi iindlela zonyango endinazo?
• Ziziphi iingenelo kunye neengxaki zokhetho ngalunye lonyango?
• Ngaba ingxaki yam yokungazali iza kusonjululwa emva kolu nyango?

I-Hyperprolactinemia inokuchaphazela umgangatho wobomi bakho kwaye iphazamise amandla akho okuba nabantwana. Kodwa eyona nto ilungileyo kukuba inokunyangeka kakuhle. Ukuba uneempawu zesi sifo, qiniseka ukuba ubona ugqirha. Emva koko uvavanyo olulula lwegazi lunokujonga amanqanaba akho e-prolactin.

Okokugqibela, yintoni ekufuneka uyikhumbule

Uyabona, i-hyperprolactinemia kukwanda kwe-hormone prolactin emizimbeni yethu. Oku kunokubangela iingxaki ezifana nobunzima bokukhulelwa abantwana, ukuncipha komnqweno wesondo, ukungahambi kakuhle komjikelo wokuya exesheni kwabasetyhini, kunye nokungabi namandla ngokwesondo kumadoda .

Eyona nto ibangela oku yi-tumor ebizwa ngokuba yi-"Prolactinoma" ekhula kwi-pituitary gland. Le meko inokubangelwa nangamayeza athile kunye nezinye izifo .

Ungakhathazeki! Kukho unyango olufanelekileyo loku. Ukuba unale mpawu, kungcono ukubona ugqirha ngokukhawuleza. Emva koko ungafumana unobangela ochanekileyo kwaye uqale unyango olukufaneleyo. Kubaluleke kakhulu ukunyamekela impilo yakho.

I- Prolactin, i-Hyperprolactinemia, i-Pituitary gland, ukungalingani kwamahomoni, ukungazali, i-Galactorrhea, i-Prolactinoma