Uma welapha wena noma othandekayo wakho ngomdlavuza, odokotela bakunikeza imithi eyahlukahlukene. I-Ivosidenib ingenye yemithi enjalo, ikakhulukazi esetshenziselwa ukwelapha umdlavuza we-bile duct kanye neminye imidlavuza yegazi nomnkantsha. Igama lingase lizwakale lingajwayelekile. Kodwa ungakhathazeki. Kulesi sihloko, sizochaza konke ngalo muthi ngendlela elula kakhulu, exoxayo.
Kalula nje, iyini i-Ivosidenib?
Cabanga ngamaseli omdlavuza njengamaseli amabi emzimbeni wethu akhula ngokushesha kakhulu futhi angalawuleki. Lawa maseli aneprotheni ekhethekile ewasiza ukuba akhule futhi ahlukane ngokushesha. Le protheni isebenza njengokunikeza amanzi nomanyolo esihlahleni esibi.
Lo muthi obizwa ngokuthi i-Ivosidenib uvimba umsebenzi walowo phrotheni . Kufana nokuvimba umanyolo emthini omubi. Khona-ke ikhono lamaseli omdlavuza lokukhula nokusabalala liyancipha kakhulu noma limiswe ngokuphelele. Lona umsebenzi oyisisekelo walo muthi. Lo muthi uvame ukutholakala emakethe ngaphansi kwegama elithi Tibsovo .
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuthatha lo muthi
Ngaphambi kokuqala noma yimuphi umuthi, kubalulekile ukunikeza udokotela wakho incazelo ephelele yesimo sakho sempilo. Lokhu kwenzelwa ukuthi ukwazi ukukhetha ukwelashwa okufanele nokuphephile kakhulu kuwe. Ngaphambi kokuqala i-Ivosidenib, qiniseka ukuthi utshela udokotela wakho uma unezinye zezimo ezilandelayo:
| Isimo sempilo noma iqiniso | Kungani kubalulekile ukwazisa udokotela? |
|---|---|
| Isifo senhliziyo noma ukungalingani kwesigqi senhliziyo | Lo muthi ngezinye izikhathi ungathinta isigqi senhliziyo, ngakho-ke uma usuvele unesifo senhliziyo, udokotela wakho kufanele aqaphele kakhulu ngalokho. |
| Isifo sesibindi | Isibindi sidlala indima enkulu ekususeni imithi emizimbeni yethu. Uma kukhona ubuthakathaka esibindini, udokotela kungadingeka ashintshe umthamo womuthi. |
| Isifo sezinso | Imithi ikhishwa emzimbeni ngezinso. Uma kunenkinga ngezinso, udokotela kufanele akwazi lokho. |
| Amazinga e-sodium, i-potassium, ne-magnesium anciphile egazini | Izinguquko kula mazinga amaminerali zingathinta izinga lokushaya kwenhliziyo. Kubalulekile ukuhlola ukuthi lokhu kungaphakathi kwamazinga ajwayelekile ngaphambi kokuqala umuthi. |
| Izifo zesimiso sezinzwa ezifana ne-Guillain-Barre syndrome | Njengoba lo muthi ungathinta isimiso sezinzwa, kubalulekile ukwazisa isiguli uma sesivele sinesifo esinjalo. |
| Ukuzama ukukhulelwa, ukukhulelwa, noma ukuncelisa | Lokhu kubaluleke kakhulu . Lo muthi ungalimaza ingane esibelethweni. Ungadlulela enganeni ngobisi lwebele. Ngakho-ke qiniseka ukuthi ukhuluma nodokotela wakho ngalokhu. |
| Ukungezwani neminye imithi, ukudla noma izinto ezithile | Uma une-allergies ku-Ivosidenib noma ezinye izithako, sicela usazise kusenesikhathi. |
Ngiyisebenzisa kanjani ngempela le mithi?
Njengoba udokotela esho, into ebaluleke kakhulu ukuthatha umthamo ofanele ngesikhathi esifanele.
- Indlela Yokuthatha: Lokhu kuza njengephilisi. Gwinya iphilisi lonke ngengilazi yamanzi. Ungaliphuli, ulichoboze, noma ulihlafune.
- Isikhathi: Zama ukuthatha lo muthi ngesikhathi esifanayo nsuku zonke. Lokhu kuzoqinisekisa ukuthi umzimba uthola umuthi ngendlela efanayo.
- Ukudla: Ungawuthatha lo muthi nokudla noma ngaphandle kokudla. Kodwa-ke, uma uzwa ubuhlungu besisu, kungcono ukuwuthatha nokudla okuthile.
- Ukudla okufanele ukugweme: Ungawuthathi lo muthi kanye nokudla okunamafutha amaningi. Isibonelo, ukudla okuthosiwe nelayisi, ukudla okulula okunamafutha, njll. Futhi, ungaphuzi ijusi yamagilebhisi . Lokhu kungathinta ukusebenza kahle komuthi.
- Ukuma: Kungakhathaliseki ukuthi uzizwa ungakhululekile kangakanani, ungayeki ukuthatha umuthi kuze kube yilapho udokotela wakho ekuyala . Ukwelashwa komdlavuza kuyindlela ende.
Kuvamile ukuzizwa ungakhululekile futhi ungaphilile kahle lapho usebenzisa imithi yokwelapha ngamakhemikhali. Lokhu kungenxa yokuthi le mithi ithinta amangqamuzana omdlavuza kanye namanye amangqamuzana amahle emzimbeni wethu. Kodwa ungakhathazeki ngakho, yazisa udokotela wakho nganoma yimiphi imiphumela emibi bese ulandela imiyalelo yakhe.
Wenzani uma uphuthelwa umthamo wemithi?
Sonke siyakhohlwa ukuphuza imithi yethu ngezikhathi ezithile. Uma lokho kwenzeka, ungakhathazeki.
- Thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula.
- Kodwa-ke, uma kungaphansi kwamahora ayi-12 ngaphambi komthamo wakho olandelayo, ungawuthathi umthamo ongawusebenzisi. Yeqa bese uthatha umthamo olandelayo ngesikhathi esihleliwe.
- Ungalokothi uthathe imithamo emibili yemithi ngesikhathi esisodwa ukuze ubuyisele umthamo ophuthelwe.
- Futhi, uma uhlanza ngemva kokuthatha iphilisi, ungalithathi elinye iphilisi ngesikhathi esifanayo. Thatha iphilisi njengenjwayelo ngesikhathi esilandelayo esihleliwe.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe umuthi omningi kakhulu, iya eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha. Noma, shayela i-National Poisons Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Eminye imithi engase ihlangane ne-Ivosidenib (Ukusebenzisana Kwemithi)
Uma uthatha i-Ivosidenib, kudingeka uqaphele kakhulu ngokusebenzisa eminye imithi. Eminye imithi ingasebenzisana nayo futhi inciphise noma inyuse ukusebenza kahle kwe-Ivosidenib, noma ibangele imiphumela emibi eyingozi.
Imithi okungafanele ithathwe ne-Ivosidenib nganoma yisiphi isizathu:
- I-Dronedarone
- I-Pimozide
- I-Thioridazine
Futhi, uma uthatha imithi elandelayo, kufanele utshele nodokotela wakho ngayo:
- Eminye imithi yokulwa namagciwane enikezwa i-HIV noma i-Hepatitis
- Imithi yokutheleleka kwesikhunta (isib. i-fluconazole, i-itraconazole, i-ketoconazole)
- Imithi yokushaya kwenhliziyo okungajwayelekile (isib. i-amiodarone, i-quinidine)
- Imithi yokwelapha ukuxhuzula (isib. i-carbamazepine, i-phenobarbital, i-phenytoin)
- Ama-hormone e-estrogen ne-progestin (angase atholakale kumaphilisi okuvimbela inzalo)
- I-Rifampin(Umuthi wesifo sofuba)
- I-St. John's wort (isengezo semifino esithathwayo empilweni yengqondo)
Lolu hlu aluphelele. Ngakho-ke tshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini kanye nezithasiselo zemithi) . Futhi, tshela udokotela wakho uma ubhema noma uphuza utshwala.
Yimiphi imiphumela emibi engaba khona yokuphuza umuthi?
Njenganoma yimuphi umuthi, i-Ivosidenib ingaba nemiphumela emibi. Eminye iyingozi, eminye ivamile. Into ebalulekile ukuqaphela lokhu futhi uthathe isinyathelo ngokushesha uma kudingeka.
| Imiphumela emibi okufanele uyibike kudokotela wakho ngokushesha | |
|---|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo. |
| Izinguquko ekushayeni kwenhliziyo | Ukuzizwa sengathi inhliziyo yakho ishaya ngokushesha, ukushaya kwenhliziyo okungajwayelekile, isiyezi, ubuhlungu besifuba, nobunzima bokuphefumula. |
| Izimpawu ze-Differentiation Syndrome | Umkhuhlane, ukukhwehlela, ubunzima bokuphefumula, ubuhlungu bamathambo, ukukhuluphala ngokuzumayo, ukuvuvukala kwamaqakala, izandla, noma izinyawo. Lesi yisimo esibi kakhulu. |
| Izinkinga zesistimu yezinzwa | Ubuhlungu ezithweni zomzimba, ukungazweli, ubunzima bokukhuluma, ubunzima bokuhamba, ukulahlekelwa yibhalansi yomzimba, ukuxhuzula. |
| Inani eliphezulu lamaseli amhlophe egazi | Umkhuhlane, ukukhathala okukhulu, ukujuluka ebusuku, ukushintsha kwamehlo, ukwehla kwesisindo. |
| Imiphumela emibi evame ukungabi mibi kakhulu, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Izinkinga zesistimu yokugaya ukudla | Uhudo, ukuqunjelwa, isicanucanu, ukulahlekelwa yisifiso sokudla. |
| Ezinye izifo ezivamile | Ukukhathala, ubuhlungu bamalunga, izilonda emlonyeni noma emphinjeni. |
Ezinye izinto okufanele uzinake ngokukhethekile
Ukukhulelwa nokuncelisa
- Kubaluleke kakhulu ukugwema ukukhulelwa ngenkathi uthatha lo muthi, ngoba ungalimaza kakhulu ingane engakazalwa. Khuluma nodokotela wakho ngendlela yokuvimbela inzalo efanele wena.
- Ungamncelisi umntwana wakho ibele ngesikhathi uthatha lo muthi futhi inyanga eyodwa ngemuva komthamo wokugcina .
Imiphumela Ekuzaleni
Lo muthi ungathinta ukuzala kwabesilisa nabesifazane. Uma uhlela ukuba nezingane esikhathini esizayo, kubalulekile ukuxoxa ngalokhu nodokotela wakho ngaphambi kokuqala ukwelashwa.
Ungagcina kanjani imithi?
- Gcina kude nezingane nezilwane ezifuywayo.
- Gcina endaweni yokushisa yegumbi (phakathi kwama-degrees Celsius angu-20-25) kude nomswakama.
- Gcina ibhodlela lemithi livaliwe kahle. Ungalisusi iphakethe le-desiccant elingaphakathi ebhodleleni.
- Ungasebenzisi imithi ephelelwe yisikhathi. Buza udokotela wakho ukuthi ungayilahla kanjani kahle imithi esele noma ephelelwe yisikhathi.
Umlayezo Wokuya Nawe Ekhaya
- I-Ivosidenib umuthi olawula ukukhula kwamaseli omdlavuza, ikakhulukazi umdlavuza we-bile duct, igazi, kanye nomnkantsha wamathambo.
- Ngaphambi kokuqala lo muthi, tshela udokotela wakho ngazo zonke izimo zakho zempilo kanye nayo yonke eminye imithi oyithathayo.
- Thatha umuthi ngesikhathi esifanayo nsuku zonke, njengoba nje udokotela wakho ekutshelile. Ungawuphuli, ungawuchobozi, noma uwuhlafune.
- Uma uhlangabezana nemiphumela emibi kakhulu (isib. ubunzima bokuphefumula, ubuhlungu besifuba, ukuvuvukala kobuso), funa iseluleko sezokwelapha ngokushesha.
- Gwema ukukhulelwa ngenkathi uthatha lo muthi.
- Uma unemibuzo noma ukukhathazeka ngalo muthi, khuluma nodokotela wakho ngakho ngokukhululekile. Ungesabi noma wenze izinqumo wedwa.
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