Ingabe uvame ukuba nomkhuhlane nokukhwehlela? Noma uzizwa sengathi ugula ngokushesha kunabanye? Mhlawumbe udokotela wakho uhlole ukuhlolwa kwegazi lakho wathi unezinga eliphansi le-IgA emzimbeni wakho. Uma uzwa leli gama, ungase wesabe bese ubuza, "Yisiphi lesi sifo?" Kodwa ungakhathazeki. Namuhla, sizoxoxa nje ngokuthi ukuntuleka kwe-IgA kuyini nokuthi ngabe kusibangela izinkinga ngempela yini.
Okokuqala, ake sibone ukuthi iyini le IgA?
Kalula nje, imizimba yethu inohlelo lokuzivikela oluvimbela izifo. Lokhu sikubiza ngokuthi uhlelo lokuzivikela . Lolu hlelo lufana nebutho ezweni lakithi. Umsebenzi waleli butho ukusivikela ngokuhlonza nokulwa nezitha zakwamanye amazwe njengamagciwane, amagciwane kanye namagciwane.
Ngakho-ke, elinye lamasosha akhethekile kuleli butho libizwa ngokuthi ama-antibodies . Elinye igama lala ma-antibodies yi-immunoglobulins. Kunezinhlobo eziningana zalawa. Elinye lawo libizwa ngokuthi i-immunoglobulin A. Silibiza ngokuthi i-IgA ngamafuphi.
Umsebenzi oyinhloko wamasosha e-IgA ukuvikela ulwelwesi lwamafinyila emgudwini wethu wokuphefumula (impumulo, umphimbo, amaphaphu), umgudu wokugaya ukudla (kusukela emlonyeni kuya emathunjini), amehlo, izindlebe, njll. Lezi yizindlela amagciwane angangena ngazo kalula emzimbeni. Ngakho-ke i-IgA iqapha la masango, ivimba izitha ezingenayo ngaphambi kokuba zingene.
Ngakho-ke kuyini ukuntuleka kwe-IgA?
Ukuntuleka kwe-IgA kusho ukuthi amasosha omzimba wakho awakwazi ukukhiqiza amasosha akhethekile abizwa ngokuthi i-IgA ngokwanele. Abanye abantu bawakhiqiza kancane kakhulu. Abanye bangase bangawakhi nhlobo.
Isizathu salokhu ukuthi uhlobo lweseli elimhlophe legazi emzimbeni wethu elibizwa ngamaseli e-B alusebenzi kahle. Lawa maseli e-B afana nezimboni ezenza ama-antibodies afana ne-IgA. Ngakho-ke uma kukhona iphutha kula mafektri, ukukhiqizwa kuyancipha.
Cabanga uhlanganisa iphazili enkulu, kodwa ishoda ngezingcezu ezimbalwa. Ngisho noma ungahlanganisa isithombe sonke, kusenezikhala lapha nalaphaya. Yilokho okwenzekayo ohlelweni lwethu lokuzivikela komzimba lapho i-IgA ilahleka. Kunomkhawulo omncane ohlelweni lokuzivikela komzimba.
Kodwa nansi into okufanele uyazi ngokuqinisekile. Iningi labantu abanesifo se-IgA abasoze babhekana nanoma yiziphi izimpawu noma izinkinga empilweni yabo yonke. Kunethuba elihle lokuthi ungaphila impilo enempilo ngokuphelele ngaphandle kokwazi ukuthi unalesi simo.
Ngakho-ke ziyini izimpawu zalokhu?
Njengoba sishilo ngaphambili, abantu abaningi abanazo izimpawu. Kodwa abanye abantu, ikakhulukazi labo abanamazinga aphansi kakhulu e-IgA, bangaba nezinkinga ezithile. Into eyinhloko ukuthi bathola izifo kaningi kunabanye. Ngenxa yokuthi umlindi emnyango ubuthakathaka, amagciwane angangena kalula.
| Izifo ezivamile | Incazelo |
|---|---|
| Ukutheleleka kwesistimu yokuphefumula | Izimo ezifana nomkhuhlane ovamile, izifo zama-sinus, izifo zomphimbo, i-bronchitis, kanye ne-pneumonia. |
| Ukutheleleka kwendlebe namehlo | Ukutheleleka kwendlebe okuvamile kanye nezifo zamehlo (ikakhulukazi amehlo apinki). |
| Ukutheleleka komgudu wokugaya ukudla | Izimo ezinjengokuhlushwa yisisu njalo kanye nesifo sohudo esingamahlalakhona zingase zibe khona. |
Ngaphezu kwalokho, abanye abantu abanesifo se-IgA basengozini encane yokuthuthukisa ezinye izimo zempilo.
- Isifuba somoya
- Ukungezwani komzimba okuhlukahlukene (Ukungezwani komzimba)
- Izifo zesistimu yokugaya ukudla, isibonelo isifo sikaCrohn noma i-ulcerative colitis .
Kungani umuntu eba nokuntuleka kwe-IgA?
Lokhu kuvame ukuba yisimo sofuzo . Okusho ukuthi, sidluliselwa kusuka kubazali kuya ezinganeni ngokusebenzisa izakhi zofuzo. Uma othile emndenini wakho enalesi simo, nawe usengozini enkulu yokuba naso.
Akuvamile kakhulu ukuthi amazinga aphansi e-IgA angaba nomthelela omubi wokusebenzisa imithi ethile. Isibonelo :
- Ezinye izidakamizwa zokucindezela amasosha omzimba
- I-Phenytoin
- I-Sulfasalazine
Ingabe ukuntuleka kwe-IgA kungabangela ezinye izinkinga?
Futhi, abantu abaningi abanazo izinkinga. Inkinga enkulu kwabanye ukugula njalo.
Kodwa-ke, abantu abanesifo sokuntuleka kwe-IgA basengozini enkulu kancane yokuthola izifo ezithile zokuzivikela komzimba kunezinye. Isifo sokuzivikela komzimba yilapho uhlelo lwethu lokuzivikela lomzimba lungasebenzi kahle futhi luqala ukuhlasela amangqamuzana ethu aphilile esikhundleni sokuhlasela abahlaseli bakwamanye amazwe.
| Izifo ezingenzeka zokuzivikela komzimba |
|---|
| I-rheumatoid arthritis: Isimo esibangela ukuvuvukala nobuhlungu emalungeni. |
| I-Lupus: Isifo esingathinta izingxenye ezahlukene zomzimba. |
| Isifo se-Celiac: Ukuzwela komzimba ku-gluten, iphrotheni etholakala kufulawa kakolweni. |
Uzizwa ukhathele ngenxa ye-IgA ephansi?
Ukuntuleka kwe-IgA ngokwakho akukubangeli ukukhathala. Kodwa-ke, uma unesifo sokuzivikela komzimba esifana ne-rheumatoid arthritis, ungase uzwe ukukhathala njengophawu lwaleso sifo. Uma uhlala uzizwa ukhathele futhi ukhathele, kubalulekile ukukhuluma nodokotela wakho ngakho.
Udokotela usithola kanjani lesi simo?
Lokhu kuvame ukutholakala ngengozi. Uma uhlolwa igazi lesinye isimo, umbiko ungase ubonise ukuthi amazinga akho e-IgA aphansi.
Noma, uma ugula njalo, noma wazi ukuthi othile emndenini wakho unalesi simo, udokotela wakho angase abe nokungabaza futhi acele ukuhlolwa kwegazi okukhethekile ukuze kuhlolwe amazinga akho e-IgA.
Yiziphi izindlela zokwelapha lokhu?
Akukho ukwelashwa noma ikhambi elithile lokuntuleka kwe-IgA. Iningi labantu alinazo izinkinga ngakho futhi alidingi ukwelashwa. Ukwelashwa kunqunyelwe ezimpawini noma ezifweni eziba khona ngenxa yalokho.
- Ukwelashwa kwezifo: Uma ungenwa yigciwane, udokotela wakho uzokunikeza ama-antibiotic afanele.
- Ukuqinisa amasosha omzimba: Akuvamile kakhulu, odokotela bangase banqume ukunikeza umuntu ovame ukuba nokutheleleka okukhulu umjovo obizwa nge-IVIG (intravenous immunoglobulin) ukuze aqinise amasosha omzimba.
- Ukwelashwa kwezinye izifo: Uma unesifo sokuzivikela komzimba esihambisana naso, kuzonikezwa ukwelashwa okufanele.
Lesi simo asikwazi ukwelapheka ngokuphelele, kodwa ezinye izingane zingase ziphinde zikwazi ukuthola okunye kokukhiqizwa kwazo kwe-IgA njengoba zikhula.
Kufanele ngimbone nini udokotela?
Uma uzizwa sengathi uhlala ugula, noma uma uthatha isikhathi eside ukululama ekuguleni okuncane, qiniseka ukuthi ubona udokotela ukuze akunike iseluleko. Akuvamile ukugula ngaso sonke isikhathi. Kubalulekile ukuthola imbangela.
Uma kukhona emndenini wakho onesifo se-IgA, tshela udokotela wakho ngakho.
Umlayezo Wokuya Nawe Ekhaya
- Ukuntuleka kwe-IgA kuyisimo esivamile esenzeka ohlelweni lwethu lokuzivikela komzimba.
- Iningi labantu abanalesi simo lingaphila impilo ejwayelekile nenempilo ngaphandle kwezimpawu .
- Abanye abantu bangase babe sengozini yokutheleleka njalo (ikakhulukazi uhlelo lokuphefumula).
- Nakuba kungekho ikhambi lalokhu, izifo ezenzekayo zingelashwa ngempumelelo.
- Uma unokungabaza noma ukwesaba ngalokhu, khuluma nodokotela wakho ngakho ngokukhululekile. Asikho isizathu sokwesaba.
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