Wo mmerɛbo no reyɛ dɛn? Momma yɛnka Liver Function Tests (LFTs) ho asɛm!

Mmɛn yɛ akwaa a ɛho hia paa wɔ yɛn nipadua mu, ɛnte saa? Ɛte sɛ adwumayɛbea ketewaa bi wɔ yɛn nipadua mu. Enti mogya mu nhwehwɛmu titiriw bi wɔ hɔ a wɔyɛ de hwɛ sɛ adwumayɛbea yi reyɛ adwuma yiye anaasɛ ɛnte saa. Ɛno ne nea yɛfrɛ no ‘mrɛbo mu dwumadi ho sɔhwɛ’ anaa mmerɛbo dwumadi ho sɔhwɛ (LFTs) . Eyi betumi ama yɛn nnuruyɛfo anya nsɛm a ɛho hia pii afa wo mmerɛbo akwahosan ho.

Dɛn nti na wɔyɛ mmerɛbo mu dwumadi ho nhwehwɛmu (LFT) yi?

Okay, afei ebia woresusuw ho sɛ, ‘Dɛn nti na wɔyɛ LFT yi?’ Ebetumi aba sɛ nneɛma pii nti na ɛte saa.

Ebia wo duruyɛfo bɛpɛ sɛ ɔhwɛ sɛ wowɔ mmerɛbo mu yare bi te sɛ hepatitis a wususuw sɛ wowɔ anaa. Anaasɛ, sɛ wowɔ mmerɛbo mu yare bi dedaw a, nhwehwɛmu yi betumi aboa ma woahu sɛnea akɔ so yiye, anaasɛ sɛ ebia ayaresa no reyɛ adwuma anaa. Ade foforo nso ne sɛ nnuru bi betumi aka mmerɛbo no. Sɛ worenom nnuru a ɛtete saa a, wɔde saa LFT ahorow yi nso di dwuma de hwɛ sɛ ebia ɛrenya wo mmerɛbo so nkɛntɛnso anaa.

Dɛn ne mmerɛbo dwumadi mu nhwehwɛmu ahorow atitiriw?

Sɛ yɛbɛka no tiawa a, saa LFT nhwehwɛmu yi susuw nneɛma pii fi wo mogya bi mu. Sɛ wonya mogya biako mpo a, ebetumi ama wɔanya enzyme ne protein ahorow a mmerɛbo no yɛ ho nsɛm. Ma yɛnhwɛ nea wɔsusuw nneɛma atitiriw no?

Mmɛn mu enzymes ho nhwehwɛmu

Saa sɔhwɛ yi hwɛ enzyme ahorow pii a ɛwɔ wo mmerɛbo mu. Sɛ nhwɛso no, enzyme ahorow te sɛ alkaline phosphatase (ALP) , alanine transaminase (ALT) , aspartate aminotransferase (AST) , ne gamma-glutamyl transferase (GGT) ne nea ɛwɔ hɔ titiriw. Sɛ mmerɛbo no sɛe anaa apira a, saa enzymes yi dodow bɛkɔ soro wɔ mogya no mu.

Protein nyinaa ho sɔhwɛ

Eyi kyerɛ protein dodow a ɛwɔ wo mogya mu. So wunim? Protein a yɛn nipadua hia no, mmerɛbo no na ɛyɛ. Enti, sɛ protein dodow no sua a, ebetumi akyerɛ sɛ mmerɛbo no ntumi nyɛ adwuma yiye.

Bilirubin nhwehwɛmu

Bilirubin yɛ ade a wɔsɛe no. Mmɛn no de kɔ akisikuru no mu. Ne dodow a ɛkɔ soro no kyerɛ sɛ ebia biribi asɛe wɔ mmerɛbo no ho.

LDH sɔhwɛ

Lactate Dehydrogenase (LDH) nso yɛ enzyme bi. Ɛwɔ yɛn nipadua mu ntini pii mu, a mmerɛbo ka ho. Ne dodow nso ka biribi fa mmerɛbo no akwahosan ho.

Prothrombin Bere (PT) nhwehwɛmu

Saa sɔhwɛ yi susuw bere tenten a egye ansa na wo mogya a wɔde ayɛ nhwɛsode no ayɛ kɛse. Mmɛn no nso yɛ protein ahorow a ehia na ama mogya atɔ. Enti sɛ egye bere tenten a, ɛno nso betumi akyerɛ mmerɛwyɛ bi wɔ mmerɛbo no dwumadi mu.

Te sɛ nhwehwɛmu ahorow yi nyinaa no, ɛtɔ mmere bi a wɔde ka mogya mu nhwehwɛmu a wɔfrɛ no Comprehensive Metabolic Panel a wɔtaa yɛ no fã.

Dɛn na yebetumi asua afi sɔhwɛ ahorow yi mu?

Fa LFT amanneɛbɔ yi sɛ detective asɛm. Wo duruyɛfo betumi aka pii akyerɛ wo denam gyinapɛn ahorow ne nsusuwii ahorow a ɛwɔ mu a ɔbɛhwɛ so. Nhwɛsoɔ:

• So wowɔ hepatitis, mmerɛbo mu ɔfe?
• Sɛ ɔfe a ɛte saa wɔ hɔ a, so nsa a wɔnom na ɛde ba, anaasɛ efi biribi foforo a ɛma nipadua no yɛ adwuma?
• So ɔhaw no wɔ mmerɛbo no ankasa mu, anaasɛ ntini a ɛma mogya tu no mu?
• So mmerɛbo no ntumi nyɛ adwuma yiye? Sɛ saa a, ɛnde akodu he?
• So akwanside bi wɔ bile a ɛsen no mu? Sɛ saa a, ɛte sɛn?
• So nnuru a wonom no bi aka wo mmerɛbo? Sɛ saa a, ɛnde akodu he?

Saa LFT ahorow yi ma yenya nneɛma pii ho nsɛnkyerɛnne.

Ɔkwan bɛn so na wɔyɛ mmerɛbo mu nhwehwɛmu (LFT) yi?

Ɛyɛ mmerɛw yiye. Wogye mogya ketewaa bi fi ntini bi a ɛwɔ wo basa mu mu. Afei wɔde kɔ lab bi na wɔsɔ hwɛ. Ɛhɔ no, wɔhwɛ sɛ ebia nneɛma ahorow dodow kɔ soro anaasɛ ɛba fam wɔ ɔkwan a ɛnteɛ so anaa. Mpɛn pii no, wɔde enzyme anaa protein ahorow dodow nso toto ho. Efisɛ sɛ wɔsakra saa kari pɛ no a, ɛnyɛ den sɛ wobɛte ase sɛ biribi asɛe wɔ mmerɛbo no ho.

Dɛn na ɛba bere a wɔreyɛ sɔhwɛ no?

Wubetumi ama wɔayɛ nhwehwɛmu yi wɔ ayaresabea anaa adwumayɛbea titiriw bi a wɔyɛ nhwehwɛmu. Mfiridwumayɛfo no bedi kan apaw ntini a ɛfata wɔ wo basa mu na wahohoro baabi a ɛwɔ no ho. Ebia wɔde compression band nso bɛhyɛ abasa no atifi na aboa ma ntini no ada nsow yiye. Afei, wɔde ade ketewaa bi hyɛ ntini no mu na wɔboaboa mogya dodow a ɛho hia ano wɔ toa ketewa bi mu. Eyi gye simma kakraa bi pɛ, na ɛnyɛ bere tenten. Mma ɛnhaw wo, ɛbɛyɛ te sɛ nea ntɛtea ketewa bi rewe wo, ɛno ara ne no.

Sɔhwɛ no akyi?

Sɛ wɔtwe mogya no wie a, wɔde nhwɛsode no kɔ aduruyɛdan bi mu ma wɔyɛ mu nhwehwɛmu. Sɛ lab no wɔ ayaresabea anaa asoɛe koro no ara mu a, ebia wobenya nea efi mu ba no ntɛm. Ebia wobetumi anya bi wɔ nnɔnhwerew kakraa bi anaa nna kakraa bi mpo mu. Sɛ woante nka sɛ wo totɔ piti bere a wode mogya ama wo akyi a, wubetumi akɔ fie, anom nnuru a wotaa de di dwuma no, na woadidi anaa woanom.

Mɛyɛ dɛn ate nea ɛwɔ me LFT amanneɛbɔ mu no ase?

Sɛ wonya wo LFT amanneɛbɔ a, wobɛhunu nneɛma ahodoɔ ho gyinapɛn. Wubetumi de atoto nea ɛfata ho na woahwɛ sɛ wo gyinapɛn ahorow no korɔn anaasɛ ɛba fam anaa. Nanso dɛn na akontaabu ahorow yi kyerɛ ankasa?Egye osuahu kakra ansa na yɛate saa asɛm no ase. Enti, wo duruyɛfo bɛkyerɛkyerɛ nea ebefi mu aba no mu akyerɛ wo na wakyerɛ wo sɛnea wobɛkenkan. Mfa nea efi mu ba yi nkutoo nsi gyinae akɛse da, ɛyɛ? Ɛyɛ papa sɛ wo ne oduruyɛfo bɛkasa.

"Nea ɛho hia ne sɛ, LFT amanneɛbɔ yɛ ahodwiriwde no fã biako pɛ. Ebia oduruyɛfo no behia nsɛm pii na ama wahu mfonini no nyinaa."

Dɛn ne mmerɛbo mu nhwehwɛmu a ɛfata? (Dɛn ne ranges a ɛyɛ daa ma LFTs?)

Eyi nso ho hia. Nnipa dodow a wɔtaa yɛ no betumi ayɛ soronko wɔ onipa biara ho. Wei kyerɛ sɛ saa gyinapɛn ahorow yi betumi ayɛ soronko kakra a egyina nneɛma te sɛ ɔbarima anaa ɔbea, nipadua kɛse, ne mpo wɔ lab biara so. Enti, ɛsɛ sɛ wode wo gyinapɛn ahorow toto ‘normal range’ a wɔakyerɛw wɔ w’amanneɛbɔ no so no ho.

Nanso, gyinapɛn ahorow bi a ɛwɔ hɔ nyinaa ni (eyinom yɛ nsɛm a ɛfa nneɛma nyinaa ho nkutoo , yɛsrɛ wo hwɛ ‘Normal Range’ pɔtee a ɛwɔ w’amanneɛbɔ no so):

• Alanine Transaminase (ALT): 0 kosi 45 IU/L (Amanaman Ntam Nkyekyɛm wɔ Lita biara mu) .
• Aspartate aminotransferase (AST): Ɛyɛ 0 kosi 35 IU/L
• Alkaline phosphatase (ALP): Ɛyɛ 30 kosi 120 IU/L
• Gamma-glutamyl transferase (GGT): 0 kosi 30 IU/L
• Bilirubin: Micromoles 2 kosi 17/L (micromoles wɔ lita biara mu) .
• Prothrombin bere (PT): Sikɔne 10.9 kosi 12.5
• Albumin: 40 kosi 60 g/L (gram lita biara) .
• Protein a ɛwɔ mu nyinaa: 6.3 kosi 8.0 g/dL (gram wɔ deciliter biara mu) .

Dɛn na AST ne ALT a ɛkɔ soro kyerɛ?

Sɛ enzymes AST ne ALT dodow kɔ soro a, ɛda adi sɛ mmerɛbo no asɛe kakra. Sɛ mmerɛbo no wɔ adwennwen mu a, saa enzymes yi na ɛda adi kɛse sɛ ɛbɛkɔ mogya no mu. Sɛ wɔma abien no nyinaa kɔ soro pɛpɛɛpɛ a, ɛda adi sɛ biribi foforo a ɛnyɛ nsa na asɛe mmerɛbo no (sɛ nhwɛso no, ɔyare mmoawa, awuduru foforo). Nanso, sɛ AST dodow no boro ALT dodow no so bɛyɛ mmɔho abien a, ɛtaa kyerɛ sɛ mmerɛbo no sɛe esiane nsa nti. Nanso, eyinom yɛ nsɛm a wɔka kyerɛ ara kwa, na ɛsɛ sɛ oduruyɛfo na ɔka no yiye.

Tebea ahorow bɛn na mmerɛbo mu dwumadi ho nhwehwɛmu (LFT) betumi aboa ma wɔahu?

Ebia mogya mu nhwehwɛmu ahorow yi nkutoo rentumi nhu mmerɛbo mu yare ko a wowɔ no yiye. Nanso, wobetumi aboa wo duruyɛfo no ma wapow tebea afoforo. Ebia wubehia nhwehwɛmu foforo na ama woahu yare no awiei koraa. Sɛ nhwɛso no, mfoninitwa nhwehwɛmu, mmerɛbo mu nhwehwɛmu, anaa wo mmerɛbo no fã ketewaa bi mu nhwehwɛmu.Anaasɛ nneɛma te sɛ mogya mu nhwehwɛmu de hu mmoawa pɔtee bi.

Tebea horow a saa LFT ahorow yi betumi akyerɛ no bi ni:

• Mmerɛbo mu yare a srade wom
• Hepatitis a awuduru wom
• Hepatitis a nipadua no tumi ko tia nyarewa
• Mpɔtorɔ mu yare a ɔyare mmoawa (A, B anaa C) .
• Hemochromatosis - dade a ɛboro so a ɛboaboa ano wɔ nipadua no mu
• Wilson yareɛ - kɔbere a ɛboro so a ɛboaboa ano wɔ nipadua no mu
• Alpha-1 antitrypsin a enni nipadua no mu
• Nsu mu akisikuru a edi kan (PBC) .
• Cirrhosis - mmerɛboɔ a ɛyɛ den na ɛyɛ akuru
• mmerɛbo mu kokoram

Nea etwa to no, nneɛma a ɛsɛ sɛ wokae (Take-Home Message) .

Enti, mmerɛbo dwumadi ho nhwehwɛmu, anaa LFT, yɛ ɔkwan a ɛyɛ mmerɛw yiye a wo ne wo duruyɛfo betumi afa so ahu wo mmerɛbo akwahosan ho ade. Sɛ́ ebia ɛyɛ mmerɛbo mu yare a worehwehwɛ anaasɛ wobɛhwɛ sɛ ebia aduru bi a wonom no renya nkɛntɛnso no, mogya ketewaa yi betumi ama woanya nsɛm pii.

Kae sɛ ebia LFT nkutoo rennɔɔso sɛ ɛbɛma wɔahu yare no koraa. Nanso, nsɛm a wubenya afi sɔhwɛ yi mu no betumi aboa kɛse ma woasi anammɔn a ɛsɛ sɛ woyɛ akyi no ho gyinae. Enti, sɛ wo duruyɛfo kamfo LFT kyerɛ a, nyansa wom sɛ wobɛyɛ a wunsuro. Wo mmerɛbo te sɛ w’adamfo paa, na ɛyɛ w’asɛyɛde sɛ wobɛhwɛ so yiye!

` Mmerɛbo, Mmerɛbo mu nhwehwɛmu, Mmerɛbo Dwumadi Ho Nhwehwɛmu, LFT, Mogya mu nhwehwɛmu, Mmerɛbo mu yare, Hepatitis