Momma yɛnhwehwɛ wo CK level no ho nsɛm. Dɛn ne saa Creatine Kinase (CK) yi?

Ɛtɔ da bi a, sɛ wokɔ oduruyɛfo nkyɛn a, ɔka kyerɛ wo sɛ yɛ mogya mu nhwehwɛmu bi, ɛnte saa? Wɔn mu biako ne sɔhwɛ yi a wɔfrɛ no CK. Enti, sɛ nnipa pii te eyi a, asɛmmisa ketewaa bi ba wɔn adwenem sɛ, "Dɛn ne CK yi?" "Adɛn nti na wɔahwɛ eyi mu?" Mma ɛnhaw wo, ɛnnɛ yɛbɛka saa CK yi ho asɛm, a egyina hɔ ma Creatine Kinase, wɔ ɔkwan tiawa bi so a wubetumi ate ase.

Dɛn ne creatine kinase (CK)?

Sɛ yɛbɛka no tiawa a, CK yɛ enzyme . Enzyme yɛ protein bi a ɛma nnuru ahorow a ɛwɔ yɛn nipadua mu yɛ adwuma ntɛmntɛm na ɛboa. Saa CK enzyme yi wɔ wo koma ntini mu titiriw (kyerɛ sɛ, ntini a ɛwɔ wo koma mu), ntini a ɛbata wo nnompe ho (yɛfrɛ eyinom `nnompe ntini`, kyerɛ sɛ, ntini a ɛboa wo ma wokanyan wo nsa ne wo nan na wonantew), na kakraa bi pɛ na ɛwɔ amemene no mu

Enti, sɛ biribi sɛe saa ntini mu nkwammoaa yi, kyerɛ sɛ, koma ntini, nnompe mu ntini, anaa amemene mu nkwammoaa a, saa nkwammoaa no mu paapae na emu nsɛm no fi adi. Ɛno ne bere a CK enzyme yi fi adi kɔ mogya no mu. Mpɛn pii no, CK kakraa bi pɛ a ɛwɔ yɛn mogya mu no fi saa nnompe ntini ahorow no mu.

Fa no sɛ woateɛteɛ w’apɔw mu denneennen. Afei wo ntini betumi asɛe kakra. Wɔ mmere a ɛtete saa mu no, CK dodow nso betumi akɔ soro wɔ mogya no mu. Afei nso, sɛ ntini mu nyarewa (`Myopathies`) wɔ hɔ a, sɛ nhwɛso no, nnipa a wɔwɔ nyarewa te sɛ `Muscular Dystrophy` nso wɔ CK dodow a ɛkɔ soro.

So CK enzyme ahorow bi wɔ hɔ?

Yiw, saa CK enzyme yi ahorow atitiriw abiɛsa na ɛwɔ hɔ. Te sɛ anuanom a wɔwɔ abusua mu no, wohu ɔkwan biara so wɔ yɛn nipadua no afã horow:

• CK-MM: Saa ɔkwan yi dɔɔso sen biara wɔ wo nnompe ntini mu .
• CK-MB: Eyi dodow no ara wɔ wo koma ntini mu .
• CK-BB: Saa ɔkwan yi dɔɔso sen biara wɔ amemene no mu ntini mu .

Ɛho hia sɛ wuhu saa ahorow yi, efisɛ sɛ CK dodow kɔ soro a, sɛ wohwɛ CK ko a ɛkɔ soro a, wubetumi anya baabi a ɔsɛe no wɔ nipadua no mu ho adwene a ɛyɛ mmerɛw.

Enti, dɛn ne creatine kinase (CK) sɔhwɛ no?

Creatine kinase (CK) nhwehwɛmu kyerɛ CK dodow a ɛwɔ wo mogya mu . Saa sɔhwɛ yi betumi ahu sɛ wo CK dodow boro sɛnea ɛte daa no so anaa. Sɛ ɛte saa a, ebetumi akyerɛ sɛ biribi asɛe anaa ɔhaw bi wɔ wo nnompe mu ntini, wo koma, anaa w’amemene mu. Saa ɔsɛe yi betumi ayɛ bere tiaa mu (ɛyɛ den) anaa bere tenten (nea enni sabea).

Wɔsan frɛ saa CK sɔhwɛ yi sɛ:

• CK nyinaa
• CK creatine a wɔde yɛ aduru
• Phosphokinase CPK na ɛyɛ adwuma

Dɛn ne creatine kinase (CK) enzyme no dwumadi?

Biribi a ɛho hia ni. Abusuabɔ kɛse biara nni CK enzyme no dwumadi a ɛfata ne nea ɛka bere a CK dodow kɔ soro wɔ mogya no mu no ntam. CK enzyme no adwuma ankasa ne sɛ ɛde phosphate kuw bi bɛka ade bi a wɔfrɛ no creatine ho wɔ yɛn ntini nkwammoaa mu. Creatine yɛ biribi a ɛboa ma ntini ahorow ma ahoɔden. Enti, sɛ CK enzyme no de phosphate ka creatine yi ho a, ɛbɛyɛ molecule a ahoɔden kɛse wom a wɔfrɛ no phosphocreatine . Yɛn nipadua de saa phosphocreatine yi yɛ ahoɔden.

Enti, sɛ wo ntini, wo koma, anaa w’amemene sɛe a, saa nkwammoaa no sɛe. Afei CK enzyme a ɛwɔ saa nkwammoaa no mu ne nneɛma afoforo kɔ mogya no mu. Saa na CK dodow a ɛwɔ mogya no mu no kɔ soro. Ɛno kyerɛ sɛ CK dodow kɔ soro, ɛnyɛ sɛnea ɛyɛ adwuma sɛnea ɛsɛ nti, na mmom esiane sɛ nkwammoaa no asɛe na CK no pue kɔ mogya no mu nti.

Dɛn na wɔde CK sɔhwɛ ahorow di dwuma?

Nnuruyɛfo taa de CK nhwehwɛmu no di dwuma de hu ntini mu haw ahorow na wɔhwɛ so . Ɛne sɛ, sɛ:

• Ntini mu nyarewa (`Ntini mu nyarewa` / `Myopathies`): Eyinom ho nhwɛso ne:
• Duchenne muscular dystrophy (DMD): Eyi yɛ yare a ɛntaa nsi, a wonya fi awo mu a ɛma nnompe mu ntini yɛ mmerɛw, sɛe, na entumi nyɛ adwuma. Ɛtaa ka mmarimaa.
• Rhabdomyolysis: Eyi yɛ tebea a ɛma ntini mu ntini no sɛe ntɛmntɛm yiye. Eyi betumi afi opira a emu yɛ den, ntini mu yare, anaa tebea foforo bi mu aba.
• Ntini mu opira: Eyinom betumi ayɛ:
• Ntini a ɛyɛ den, ɛyɛ den, ɛtetew, anaa twetwe esiane akwanhyia anaa apɔw-mu-teɛteɛ a ɛboro so nti.
• Ɔhyew a ɛto so abiɛsa.
• Ɛlektrik a ɛma anyinam ahoɔden.
• Ntini mu ɔfe (Myositis): Eyi ho nhwɛso ahorow bi ne:
• Polymyositis: Eyi yɛ yare a ɛma ntini no yɛ mmerɛw. Ɛtaa ka ntini a ɛbɛn nipadua no dua no.
• Dermatomyositis: Eyi yɛ tebea a ɛntaa nsi a ɛma ntini yɛ mmerɛw na ɛma honam ani sɛe.
• Pyomyositis: Eyi yɛ ɔyare mmoawa a wɔntaa nhu ntini ahorow no. Ɛtaa de akisikuru ba.

Esiane sɛ ɛtɔ mmere bi a ntini mu sɛnkyerɛnne betumi ayɛ tebea afoforo pii ho sɛnkyerɛnne nti, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ nhwehwɛmu afoforo pii nka CK nhwehwɛmu no ho. Nhwɛsoɔ:

• Nneɛma a ɛma anyinam ahoɔden
• BUN (mogya mu urea nitrogen) .
• Creatinine a wɔde yɛ aduru
• Myoglobin a ɛwɔ nsu mu

CK nhwehwɛmu ne koma a entumi nyɛ adwuma yiye

Bere bi a atwam no, na wɔde CK nhwehwɛmu no di dwuma de hu sɛ obi anya komayare. Nanso seesei wɔntaa nyɛ. Efisɛ mprempren wɔde Troponin na edi dwuma.Sɔhwɛ foforo bi wɔ hɔ a wɔfrɛ no troponin, a eye sen CK wɔ koma a asɛe a wohu mu. Ɛno nti na mprempren, mpɛn pii no, sɛ wosusuw sɛ komayare bi , troponin ne sɔhwɛ a wɔhwɛ mu.

Dɛn nti na mihia CK sɔhwɛ?

Sɛ wowɔ ntini mu yare ho sɛnkyerɛnne a, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ CK nhwehwɛmu. Saa sɛnkyerɛnne ahorow yi bi ne:

• Ntini mu yaw ne/anaasɛ ɛyɛ den.
• Ntini mu mmerɛwyɛ.
• Ɔhaw ahorow a ɛfa nipadua a ɛkari pɛ ho.
• Ntini a ɛyɛ mmerɛw anaasɛ ɛyɛ mmerɛw.
• Nsu a ne kɔla yɛ tuntum (te sɛ kɔkɔɔ).

Afei nso, sɛ wo ntini apira anaasɛ woabɔ akisikuru a, ebia ɛho behia nso sɛ wɔyɛ sɔhwɛ yi saa bere no. Wɔ opira ahorow bi mu no, ebetumi agye nna abien ansa na CK dodow akɔ soro. Enti ebia ebehia sɛ woma wɔyɛ sɔhwɛ yi bɛboro pɛnkoro.

Hena na ɔyɛ CK sɔhwɛ no?

Mpɛn pii no, akwahosan ho dwumayɛni bi a wɔfrɛ no phlebotomist na ɔfa mogya, kyerɛ sɛ, mogya a wɔde yɛ CK nhwehwɛmu . Nanso, akwahosan ho dwumayɛni biara a wɔatete no sɛ ɔmfa mogya no betumi ayɛ eyi. Afei wɔde mogya no kɔ baabi a wɔyɛ nhwehwɛmu. Ɛhɔ no, nyansahufo bi a ɔwɔ aduruyɛdan mu siesie nhwɛsode no na ɔde mfiri a wɔde hwehwɛ nneɛma mu sɔ hwɛ .

Mɛyɛ dɛn asiesie me ho ama CK sɔhwɛ no?

Mpɛn pii no, biribiara nni hɔ a ɛsɛ sɛ woyɛ de siesie wo ho pɔtee ma CK mogya mu nhwehwɛmu.

Nanso, sɛ wo duruyɛfo rehyɛ sɛ wɔmfa CK nhwehwɛmu yi nkɔhwehwɛ ntini mu haw biara a, ɛsɛ sɛ woto w’apɔw-mu-teɛteɛ a emu yɛ den no ano hye wɔ nna a edi nhwehwɛmu no anim no mu. Nea enti a ɛte saa ne sɛ apɔw-mu-teɛteɛ nso betumi ama ntini ahorow no ayɛ basaa bere tiaa bi, na ebetumi ama CK dodow akɔ soro wɔ mogya no mu. Enti, yɛ wo dwumadi ahorow a wotaa yɛ no ara kwa.

Dɛn na ɛsɛ sɛ wohwɛ kwan bere a woreyɛ CK mogya mu nhwehwɛmu no?

Eyi ne nea ɛba bere a wode mogya ma no:

1. Wobɛtena nkongua so. Akwahosan ho dwumayɛni no behu ntini bi a ɛnyɛ den wɔ wo basa mu a obetumi atwe mogya afi mu. Mpɛn pii no, wɔpaw ntini bi wɔ wo basa no mu, wɔ ɔfã a ɛne wo nsateaa di nhwɛanim no.

2. Sɛ wohu ntini no wie a, wɔhohoro baabi a ɛwɔ no na wɔde aduru a ekum ɔyare mmoawa gu so.

3. Afei, wɔde ade ketewaa bi hyɛ saa ntini no mu na wɔfa mogya. Saa bere yi de, ebia wobɛte nka sɛ ntɛtea ketewaa bi aka wo.

4. Sɛ wɔde ade no hyɛ mu wie a, wɔbɛboaboa mogya kakra ano wɔ afiri bi a wɔde yɛ nhwehwɛmu mu.

5. Sɛ wɔfa mogya no wie a, woyi ade no na wɔde kotoku anaa gauze bi gu beae no na wɔde nhyɛso gu so na ama mogya no agyae.

6. Afei wɔde plaster gu beae no so. Ɛno ne no.

Saa adeyɛ yi nyinaa gye nea ennu simma anum.

Dɛn na ɛba wɔ CK sɔhwɛ no akyi?

Sɛ wɔfa wo mogya wie a, wɔde kɔ aduruyɛdan mu. Sɛ nhwehwɛmu no aba wie a, wo duruyɛfo no bɛma woahu nea efii mu bae.

So asiane bi wɔ CK mogya mu nhwehwɛmu mu?

Mogya mu nhwehwɛmu yɛ aduruyɛ mu nhwehwɛmu a abu so yiye, a ɛho hia. Asiane kɛse biara nni mogya a wɔde ma mu. Ebia wobɛte yaw kakra anaasɛ woapirapira baabi a wɔtwee mogya no. Nanso ɛno bɛkɔ yiye ntɛm.

Bere bɛn na mehu nea efii CK sɔhwɛ no mu bae?

Mpɛn pii no, ɛsɛ sɛ wunya wo CK sɔhwɛ no mu aba wɔ da koro anaa nnanu ntam , nanso ɛtɔ mmere bi a ebetumi agye bere tenten.

Dɛn na nea efi CK sɔhwɛ mu ba no ka kyerɛ yɛn?

Mogya mu nhwehwɛmu amanneɛbɔ, kyerɛ sɛ, CK nhwehwɛmu amanneɛbɔ, taa kura nsɛm a edidi so yi:

• Mogya mu nhwehwɛmu no din, anaa nea wɔsusuu wɔ wo mogya mu.
• Wo mogya mu nhwehwɛmu aba no dodow anaa susuw.
• Nsusuwii a ɛfata ma saa sɔhwɛ no.
• Nsɛm te sɛ sɛ ebia nea efi mu ba no yɛ nea ɛfata, ɛnyɛ nea ɛfata, ɛkorɔn, ɛba fam, ɛyɛ papa, anaasɛ ɛnyɛ papa.

Dɛn ne creatine kinase (CK) dodow a ɛfata?

CK dodow a ɛfata wɔ ɔpanyin a ɔwɔ apɔwmuden mu no betumi ayɛ soronko a egyina nneɛma pii so:

• Wo bɔbeasu .
• Wo mmirikatu no .
• Wo dwumadi dodow (kyerɛ sɛ, apɔw-mu-teɛteɛ ne nipadua mu mmɔdenbɔ dodow a woyɛ).

Afei nso, saa kwan a ɛfata yi betumi ayɛ soronko a egyina akwan a wɔfa so yɛ sɔhwɛ a lab biara fa so. Enti, hwɛ reference range a wɔde ama wɔ wo lab amanneɛbɔ so bere nyinaa. Sɛ wɔkyekyem pɛpɛɛpɛ a, mmarima wɔ CK dodow a ɛkɔ soro kakra sen mmea.

Nnipa a wɔn ntini mu duru dɔɔso (i.e., wɔn a wɔn nipadua mu srade pii) nso betumi anya CK dodow a ɛkɔ soro sen afoforo.

Dɛn na creatine kinase (CK) dodow a ɛkɔ soro no kyerɛ?

Sɛ wo CK dodow kɔ soro, anaasɛ wo CK dodow kɔ soro bere nyinaa wɔ CK nhwehwɛmu a wɔyɛ no mpɛn pii mu a, ɛtaa kyerɛ sɛ nnansa yi ara na wo ntini bi asɛe. Nanso, CK nhwehwɛmu nkutoo ntumi nhu ntini a asɛe no ankasa, anaa nea ɛde ɔsɛe no bae.

Nea ɛho hia: Sɛ wo CK dodow kɔ soro a, mma wo ho nnpopo. Ebia ɛho behia sɛ wo duruyɛfo yɛ nhwehwɛmu pii na ama wahu nea ɛde ba.

Nnuruyɛfo taa yɛ CK nhwehwɛmu ahorow de hwɛ sɛnea wo CK dodow resakra. Sɛ wo CK dodow kɔ soro na afei ɛso tew nkakrankakra a, ɛno kyerɛ sɛ wo ntini a asɛe no so retew. Nanso sɛ wo CK dodow kɔ so kɔ soro, anaasɛ ɛkɔ so yɛ kɛse a, ebetumi akyerɛ sɛ worehyia ntini a ɛkɔ so sɛe anaasɛ wo ntini mu sɛe.

Sɛ nea efi mu ba no kyerɛ sɛ wo CK dodow dɔɔso sen sɛnea ɛte daa a, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ nhwehwɛmu wɔ CK enzyme ahorow a madi kan aka ho asɛm (CK-MM, CK-MB, CK-BB) no ho na aboa ma wɔahu ntini ko a asɛe:

• CK-MM enzymes: Sɛ saa dodow yi dɔɔso a, ebetumi akyerɛ sɛ ntini mu opira anaa ntini mu yare, sɛ nhwɛso no, tebea bi te sɛ ntini mu yare anaa rhabdomyolysis.
• CK-MB enzyme: 1 .Sɛ saa dodow yi dɔɔso a, ebetumi akyerɛ sɛ wo koma ntini mu ayɛ wo hyew, anaasɛ worenya komayare anaasɛ woanya bi nnansa yi ara.
• CK-BB enzymes: Sɛ saa dodow yi dɔɔso a, ebetumi akyerɛ sɛ woanya akisikuru anaa w’amemene mu opira.

Nneɛma afoforo nti a creatine kinase (CK) dodow betumi akɔ soro

Ayaresa mu tebea horow bi ne opira a ɛne wo ntini nni abusuabɔ tẽẽ nso betumi ama CK dodow akɔ soro. Nea ɛde ba no bi ni:

• Endocrine yare, te sɛ thyroid yare, Addison yare, anaa Cushing yare.
• Oprehyɛn a wɔyɛ no bere tenten.
• Akisikuru a ɛma obi ho kyere no.
• Nyarewa (yare mmoawa, mmoawa, fungal anaa parasitic).
• Ntini a ɛka bom yɛ nyarewa, sɛ nhwɛso no, lupus ne ntini mu yare.
• Celiac yare a ɛwɔ nipadua no mu.
• Adwene mu yare a entumi nyɛ adwuma yiye.
• Atiridiinini a emu yɛ den a ɛma wowosow.
• Mogya a ɛtwetwe.
• Aduru anaa awuduru biara a ɛmma ntini ahoɔden ntumi nyɛ adwuma anaasɛ ɛma ahoɔden a wɔhwehwɛ no yɛ kɛse.
• Bere a wɔde nnuru a wɔde twitwiw nipadua no rema no.

So ɛsɛ sɛ mehaw me ho sɛ me creatine kinase (CK) dodow dɔɔso sen sɛnea ɛte daa a?

Sɛ mpo wo CK nhwehwɛmu no mu aba kyerɛ sɛ wo CK dodow kɔ soro a, ɛnkyerɛ sɛ wowɔ ayaresa tebea bi. Wo CK dodow betumi akɔ soro bere tiaa bi esiane nneɛma pii nti, te sɛ apɔw-mu-teɛteɛ, nnuru bi a wobɛnom, anaa nnuru a wɔde twitwiw wo mu. Ɛsan nso betumi aba sɛ biribi ankɔ yiye wɔ sɔhwɛ no mu.

Sɛ wo duruyɛfo resi gyinae wɔ nea ebefi mu aba no ho a, obesusuw nneɛma pii ho, te sɛ nnuru a wonom mprempren, w’asetra kwan, ne wo sɛnkyerɛnne ahorow. Ɔbɛka akyerɛ wo sɛ ebia wuhia sɔhwɛ foforo anaa.

Sɛ wowɔ nsɛmmisa bi fa nea efi mu ba no ho a, nsuro sɛ wo ne wo duruyɛfo bɛkasa.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Mpɛn pii no, ntini mu yaw ne mmerɛwyɛ yɛ bere tiaa mu de. Nanso sɛ wowɔ ntini mu haw ahorow a ɛkɔ so , ne wo duruyɛfo nka wo sɛnkyerɛnne ahorow ho asɛm. Ɔbɛhyɛ sɛ wɔnyɛ CK nhwehwɛmu ne nhwehwɛmu afoforo de bɔ mmɔden sɛ obehu nea ɛde wo sɛnkyerɛnne ahorow no ba.

Ɛyɛ ade a ɛfata sɛ wobɛte ehu nka bere a wuhu sɔhwɛ bi a ɛnyɛ ne kwan so no. Nanso kae sɛ, CK dodow a ɛkɔ soro no nkyerɛ ankasa sɛ wowɔ yare a emu yɛ den na wuhia ayaresa. Wo duruyɛfo bɛka akyerɛ wo sɛ wuhia nhwehwɛmu pii na ama woahu nea ɛde dodow a ɛnteɛ no ba anaa. Nsuro sɛ wubebisa wo duruyɛfo nsɛm. Wɔwɔ hɔ sɛ wɔbɛboa wo.

Nneɛma a ɛsɛ sɛ wokae fi asɛm yi mu (Take-Home Message) .

Okay, enti yɛaka CK ho asɛm pii nnɛ, ɛnte saa? Nneɛma kakraa bi a ɛsɛ sɛ wokae tiawa ni:

• CK yɛ enzyme a ɛboaboa ano wɔ mogya no mu bere a asɛe ntini, koma, anaa amemene no.
• CK nhwehwɛmu kyerɛ CK dodow a ɛwɔ mogya no mu. Sɛ ɛkɔ soro a, ebetumi akyerɛ sɛ ntini asɛe.
• Nneɛma pii betumi ama CK akɔ soro. Ebetumi nso afi nneɛma te sɛ apɔw-mu-teɛteɛ, nnuru bi, ne opira mu aba.
• Worentumi nhu yare bi ho asɛm yiye denam wo CK dodow a wobɛhwɛ kɛkɛ so. Wo duruyɛfo no begyina wo yare no ho sɛnkyerɛnne afoforo ne nhwehwɛmu afoforo a efi mu ba so besi gyinae.
• Sɛ wowɔ nsɛmmisa bi fa wo CK amanneɛbɔ ho a, nsuro sɛ wobɛbisa wo duruyɛfoɔ.

Enti, mewɔ anidaso sɛ saa nsɛm yi ho bɛba wo mfaso. Kɔ so nya apɔwmuden!

` Creatine Kinase, CK Sɔhwɛ, Ntini mu Ɛyaw, Ntini mu Yare, Enzymes, Mogya mu Nhwehwɛmu, Akwahosan