Dɛn na wo ALT sɔhwɛ amanneɛbɔ no ka? (Alanine Aminotransferase - ALT) a ɛyɛ adwuma wɔ ɔkwan a ɛyɛ mmerɛw so.

So woahu mogya mu nhwehwɛmu amanneɛbɔ bi a nkyerɛwde abiɛsa ne nɔma wɔ so pɛn? Ebia oduruyɛfo no aka akyerɛ wo sɛ bo a ɛsom no korɔn sen dodow a ɛfata. Ɛyɛ ade a ɛfata sɛ wobɛte ehu ne ehu nka kakra wɔ bere a ɛte sɛɛ mu. "Oh, dɛn ne ALT yi? So ɛyɛ yare a emu yɛ den sɛ ɛkɔ soro a?" Ebia wubesusuw ho. Nanso mma ɛnhaw wo. Ɛnnɛ, momma yɛnka nea ALT yi yɛ ne nea sɔhwɛ yi ka ankasa fa yɛn nipadua ho no ho asɛm tiawa na emu nna hɔ.

Sɛ yɛbɛka no tiawa a, dɛn ne ALT Sɔhwɛ yi?

ALT nhwehwɛmu yɛ mogya mu nhwehwɛmu a ɛnyɛ den koraa a ɛhwɛ sɛ ebia wo mmerɛbo no asɛe anaa . Ɛwom sɛ yɛde ne din tiawa frɛ no ALT de, nanso ne din mũ nyinaa ne Alanine Aminotransferase . Bere bi a atwam no, na wɔsan frɛ no SGPT (serum glutamic-pyruvic transaminase) . Ebia woahu saa wɔ w’amanneɛbɔ dedaw no mu.

Enti saa ALT yi yɛ enzyme a ɛwɔ yɛn nipadua mu. Sɛ yɛbɛka no pɛpɛɛpɛ a, saa enzyme yi wɔ yɛn mmerɛbo mu nkwammoaa mu kɛse. Wohu kakraa bi pɛ nso wɔ mmeae te sɛ asaabo ne ntini. Mpɛn pii no, ALT wɔ yɛn mogya mu wɔ dodow a ɛba fam koraa mu.

Fa mmerɛbo no sɛ kɛntɛn a nkesua pii wom. Bere tenten a nkesua no yɛ nea asiane biara nni ho no, ɔhaw biara nni ho. Nanso sɛ kɛntɛn no sɛe anaa ɛwosow a, nkesua no bi bɛbubu na apue, ɛnte saa? Saa na ɛte. Sɛ mmerɛbo mu nkwammoaa sɛe esiane yare, nnuru, akwanhyia, anaa biribi foforo nti a, ALT enzyme a ɛwɔ saa nkwammoaa no mu no fi mogya no mu. Ɛno ne bere a mogya mu nhwehwɛmu kyerɛ sɛ ALT dodow akɔ soro.

Dɛn nti na mmerɛbo ho hia yɛn nipadua saa?

Ɛnyɛ sɛ mmerɛbo yɛ akwaa akɛse a ɛwɔ yɛn nipadua mu no mu biako nko, na mmom ɛte sɛ yɛn nipadua no "adwumayɛbea titiriw" nso. Adwuma a ɛyɛ no nyɛ ade ketewaa bi.

• Bile a ɛba: Bile a ɛboa ma yɛyam nnuan a srade wom a yedi no, mmerɛbo no na ɛyɛ.
• Mogya a wɔtew ho: Mmɛn no yi nwura ne awuduru a yɛmpɛ (te sɛ nsa) fi yɛn mogya mu, te sɛ nsu a wɔde yiyi mu.
• Mogya a ɛboa ma mogya tu: Mmɛn no ma protein ahorow a ehia na ama mogya atɔ bere a obi apira no.
• Aduannuru a wɔde sie: Wɔkora nneɛma te sɛ vitamin ne minerals so na wɔkora so kosi sɛ nipadua no behia.
• Asikre dodow a wɔhwɛ so: Wɔkora asikre a ɛboro so wɔ mogya no mu na wɔsan dan no ahoɔden bere a ɛho hia no.

Enti, esiane sɛ ɛyɛ nneɛma a ɛho hia pii nti, ɛho hia paa sɛ yɛhwɛ mmerɛbo no akwahosan so.

Tebea bɛn mu na oduruyɛfo bɛka akyerɛ wo sɛ yɛ nhwehwɛmu yi?

Nneɛma pii nti na wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ ALT nhwehwɛmu. Ebetumi aba sɛ esiane sɛ wowɔ sɛnkyerɛnne ahorow a ɛfa mmerɛbo mu yare ho nti, anaasɛ ebetumi aba sɛ esiane sɛ wowɔ asiane mu sɛ mmerɛbo no bɛsɛe nti.

Ɛtɔ mmere bi a, esiane ntease pɔtee biara nti, wobetumi ayɛ ALT nhwehwɛmu no sɛ wo afe afe aduruyɛ mu nhwehwɛmu no fã. Wɔde di dwuma nso de hwɛ sɛnea ayaresa reyɛ adwuma yiye sɛ wowɔ mmerɛbo mu yare dedaw a.

So ahosiesie bi wɔ hɔ ansa na wɔayɛ sɔhwɛ no?

Mpɛn pii no, sɛ wɔyɛ ALT sɔhwɛ no nkutoo a, ɛho nhia sɛ wɔyɛ ahosiesie titiriw biara. Nanso, wɔtaa yɛ nhwehwɛmu yi de ka mmerɛbo mu nhwehwɛmu afoforo (liver panel) ho. Ebia sɔhwɛ ahorow yi bi bɛhwehwɛ sɛ wudi mmuada nnɔnhwerew kakraa bi. Enti, bisa wo duruyɛfo sɛ ɛsɛ sɛ wokwati adidi anaa anonne ansa na woayɛ nhwehwɛmu no anaa.

Afei nso, hwɛ hu sɛ wobɛka nnuru, vitamin, anaa nnuru foforo biara a wode bɛma wo ho asɛm akyerɛ wo duruyɛfo. Nnuru bi betumi aka nea efi sɔhwɛ yi mu ba no. Afei nso, apɔw-mu-teɛteɛ kɛse da a edi sɔhwɛ no anim no betumi ama ALT dodow akɔ soro bere tiaa bi. Enti ɛyɛ papa sɛ wobɛbɔ wo duruyɛfo amanneɛ wɔ ɛno nso ho.

Sɛ amanneɛbɔ no ba a, ɛkyerɛ dɛn?

Wo nsa bɛka sɔhwɛ no aba wɔ nnɔnhwerew kakraa bi anaa nna kakraa bi mu. Amanneɛbɔ no bɛkyerɛw wo ALT dodow ne ne dodow a ɛfata .

ALT dodow a ɛkorɔn

ALT dodow a ɛkɔ soro kyerɛ sɛ mmerɛbo mu nkwammoaa no ayɛ hyew anaasɛ asɛe bi. Nanso, ɛno nkutoo nkyerɛ sɛ wowɔ mmerɛbo mu yare a emu yɛ den.

Nneɛma pii betumi ama ALT dodow akɔ soro:

• Mmerɛbo mu yare a srade wom: Eyi yɛ tebea a mprempren wɔtaa hu wɔ ɔmanfo mu.
• Nyarewa a efi mmoawa mu te sɛ Hepatitis A, B, ne C: Eyinom ka mmerɛbo no tẽẽ.
• Nsã a wɔnom boro so: Nsã yɛ awuduru ma mmerɛbo no.
• Nnuru bi mu nsunsuanso bɔne: Nnuru bi a wɔde kum ɛyaw, nnuru a ɛma mogya mu srade so tew, ne nnuru a ekum ɔyare mmoawa betumi ama ALT dodow akɔ soro.
• Cirrhosis a ɛwɔ mmerɛbo mu: Akuru a ɛba mmerɛbo mu.
• Mogya a ɛkɔ mmerɛbo no mu a ɛso tew.
• Hemochromatosis: Dade a ɛboro so wɔ nipadua no mu.
• Nyarewa afoforo a efi mmoawa mu, te sɛ mononucleosis (mono).

ALT dodow a ɛba fam

Wɔntaa nhu eyi. Mpɛn pii no, ALT dodow a ɛba fam no nyɛ ade a ɛhaw adwene. Nanso, ɛntaa nsi koraa sɛ wobetumi de abata tebea horow te sɛ vitamin B6 a enni nipadua mu anaasɛ asaabo mu yare a enni sabea ho. Sɛ wo dodow sua a, ɛda adi sɛ wo duruyɛfo bɛhyɛ sɛ wɔnyɛ nhwehwɛmu foforo bi.

Nhwehwɛmu afoforo bɛn na wɔyɛ na ama wɔanya mmerɛbo akwahosan ho mfonini a edi mũ?

ALT sɔhwɛ no yɛ ahodwiriwde no fã biako pɛ. Sɛ wubehu mfonini no nyinaa a, wo duruyɛfo no behia asinasin kakraa bi bio. Ɛno nti na wɔtaa yɛ ALT sɔhwɛ no sɛ sɔhwɛ ahorow a wɔfrɛ no "Liver Function Tests" (LFTs) no fã.

Enzyme foforo a ɛho hia wɔ sɔhwɛ ahorow a ɛtoatoa so yi mu ne AST (Aspartate Aminotransferase) . Te sɛ ALT no, saa enzyme yi nso wɔ mogya no mu bere a mmerɛbo mu nkwammoaa asɛe no. Nanso, AST nso wɔ dodow a ɛkɔ soro sen ALT wɔ mmeae te sɛ koma ne ntini mu.

Wo duruyɛfo no de wo AST ne ALT dodow (AST/ALT ratio) bɛtoto ho . Saa nsusuwii yi ma wo duruyɛfo nya biribi a ɛho hia a ɛkyerɛ sɛnea mmerɛbo no sɛe ne nea ɛde ba.

Bio nso, LFT sɔhwɛ ntoatoaso no nso betumi ayɛ nea edidi so yi:

• Bilirubin a wɔde di dwuma
• Albumin a wɔde yɛ adwuma
• Alkaline phosphatase (ALP) a wɔde yɛ aduru a wɔfrɛ no phosphatase (ALP) .
• Protein a ɛyɛ ne nyinaa
• Gamma-glutamyl a wɔde fa nneɛma mu (GGT) .

Sɛ wo duruyɛfo no ka nsɛm a efi nhwehwɛmu ahorow yi nyinaa mu bom a, obetumi aka wo mmerɛbo akwahosan ho asɛm pɛpɛɛpɛ.