Yenim sɛ kokoram ayaresa a wɔbɛkɔ no betumi ayɛ adwuma a ɛyɛ den. Ɛtaa ba sɛ nsɛmmisa bɛba w’adwenem bere a wo duruyɛfo ka aduru foforo bi ho asɛm no. Ɛnnɛ, yɛbɛka aduru pɔtee bi a ɛte saa a ɛko tia kokoram, Aldesleukin, ho asɛm. Ɛtɔ mmere bi nso a wɔfrɛ no IL-2. Ma yɛnhwɛ nea saa aduru yi yɛ, nea ɛyɛ, ne nea ɛsɛ sɛ wuhu fa ho bere a worenom no.
Aduru bɛn na Aldesleukin yɛ?
Sɛ yɛbɛka no tiawa a, Aldase yɛ kokoram aduru. Nanso ɛnte sɛ nnuru a wɔde sa yare a yɛtaa te ho asɛm no. Ɛyɛ aduru a ɛma nipadua no tumi ko tia nyarewa ankasa . Ɛno kyerɛ sɛ sɛ́ anka ebekum kokoram nkwammoaa tẽẽ no, ɛkanyan w’ankasa nipadua no mu tumi a ɛko tia nyarewa no na ɛma no ahoɔden de ko tia kokoram nkwammoaa . Ɛte sɛ nea yɛtete "asraafo" (immune cells) a wɔwɔ yɛn nipadua mu no na yɛsoma wɔn ma wɔko tia ɔtamfo a wɔfrɛ no kokoram no.
Wɔde saa aduru yi (aduru din: Proleukin) di dwuma titiriw ma:
- Wɔ adwene mu nkwammoaa mu kokoram a emu nyɛ den anaasɛ ɛkɔ akyiri ho .
- Wɔ melanoma a ɛkɔ akyiri, honam ani kokoram a emu yɛ den ho.
Wɔ tebea horow bi mu no, ebia nnuruyɛfo nso bɛkamfo aduru yi akyerɛ wɔ kokoram ahorow afoforo ho.
Nneɛma a ɛho hia sen biara a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ayaresa ase
Ansa na wubesi gyinae sɛ ebia saa ayaresa yi fata wo no, ɛho hia sɛ wobɔ wo duruyɛfo amanneɛ wɔ w’akwahosan ho abakɔsɛm a edi mũ ho. Hwɛ hu sɛ wobɛka tebea horow a edidi so yi mu biara ho asɛm akyerɛ wɔn, titiriw:
- Sɛ wowɔ mogya mu haw biara (e.g. mogya a ɛtwetwe, mogya a ɛtɔ kɔ nipadua mu).
- Sɛ wote nka bere nyinaa sɛ woabrɛ anaasɛ woabrɛ a .
- Sɛ wowɔ atiridii anaa tebea foforo a ɛde ɔyare mmoawa ba nipadua no mu dedaw a.
- Sɛ wowɔ koma, ahurututu, asaabo anaa mmerɛbo mu yare biara a.
- Sɛ wowɔ ɔhaw afoforo a ɛfa nipadua no mu tumi a ɛko tia nyarewa ho a .
- Sɛ wowɔ adwenemyareɛ (e.g. adwenemhaw) anaasɛ worenom nnuru ama no a.
- Sɛ wɔadi kan ayɛ wo akwaa foforo a .
- Sɛ wowɔ akisikuru a .
- Sɛ wowɔ yafunu mu haw anaa aduan mu nyarewa a.
- Sɛ wowɔ thyroid haw ahorow a .
- Sɛ wo ho yɛ wo hyew wɔ aldesleukin anaa aduru foforo biara, aduan, anaa ade a wɔde yɛ ade ho a .
- Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaasɛ woyɛ ɛna a ɔma nufu a .
Saa nsɛm yi ho hia yiye ma w’ahobammɔ, efisɛ egyina saa nsɛm yi so na oduruyɛfo no besi ayaresa a ɛfata na ahobammɔ wom sen biara ama wo ho gyinae.
Ɔkwan bɛn so na wɔde saa aduru yi bɛma wo?
Eyi nyɛ aduru a wubetumi de akɔ fie. Wɔde aldase ma wɔ ayaresabea anaa ayaresabea, a nnuruyɛfo ne ayarehwɛfo hwɛ so yiye . Wɔtaa de ma sɛ nea wɔde gu ntini mu (wɔde fa ntini mu anaa wɔde fa IV mu) . Ɛtɔ da bi nso a wobetumi de ama sɛ aduru a wɔde twitwiw honam ani (subcutaneous injection).
Esiane sɛ wɔde saa ayaresa yi ma wɔ ayaresabea nti, ɛnsɛ sɛ wohaw wo ho sɛ wobɛyera dodow bi anaasɛ wobɛnom boro so. Aduruyɛ kuw no bɛhwɛ so kɛse.
Sɛ wususuw sɛ woanom nnuru a ɛboro so wɔ akwanhyia mu a, ka kyerɛ oduruyɛfo anaa ɔyarehwɛfo ntɛm ara. Wɔ tebea biara a egye ntɛmpɛ mu no, wubetumi akɔ ayaresabea no Emergency Treatment Unit (ETU) , na sɛ awuduru ho haw bi ba a, wubetumi afrɛ National Poisons Information Center a ɛwɔ Colombo National Hospital .
Hwɛ yiye wɔ nnuru afoforo a wonom ho.
Sɛ worenom aldesleukin a, ɛho hia sɛ woka nnuru afoforo a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo. Nnuru bi betumi ne saa ayaresa yi adi nkitaho. Enti, ɛsɛ sɛ wofa:
- Nnuru afoforo a wɔde ko tia kokoram (e.g. doxorubicin, methotrexate) .
- Nnuru a ekum ɔyare mmoawa, titiriw aminoglycosides
- Nnuru a wɔde sa mogya mmoroso (e.g. beta blockers) .
- Adwene mu akwahosan ho nnuru (ma adwenemhaw, dadwen) .
- Steroid ahorow (sɛ nhwɛso no, prednisone, cortisone) .
- Nnuru a wɔde kum ɛyaw, titiriw NSAID (e.g. ibuprofen, naproxen) .
- Nnuru a wɔde da
- Nnuru afoforo a ɛma nipadua no tumi ko tia nyarewa te sɛ interferon alfa
Wɔ saa nsɛm a wɔahyehyɛ yi akyi no, mma wo werɛ mmfi sɛ wobɛka vitamin biara, nhabannuru a wɔde ma, ne sɛ wonom sigaret anaa wonom nsa biara ho asɛm akyerɛ wo duruyɛfo .
Nneɛma a ɛsɛ sɛ wohwɛ so titiriw bere a wɔreyɛ ayaresa no
- Hwɛ a wobɛkɔ so: Nnuruyɛfo ne ayarehwɛfo bɛhwɛ wo yiye wɔ bere a wɔde saa ayaresa yi nyinaa mu.
- Mogya mu nhwehwɛmu: Ɛho behia sɛ woyɛ mogya mu nhwehwɛmu daa na ama woahu sɛnea w’ayaresa no rekɔ so na woahu nea efi mu ba ntɛm.
- Ahobammɔ a wɔde bɔ nipadua no ho ban fi nyarewa ho: Saa aduru yi betumi atew tumi a nipadua no wɔ sɛ ɛko tia nyarewa no so bere tiaa bi. Enti,Bɔ mmɔden sɛ wobɛtwe wo ho afi nnipa a wɔwɔ atiridii anaa atiridiinini ho. Sɛ wunya atiridii anaa ɔyare mmoawa bere a worenom aduru no a, nnyɛ wo ho aduru na bɔ wo duruyɛfo amanneɛ ntɛm ara.
- Nneɛma a ɛtaa yɛ yaw: Ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ wo ho nyɛ wo dɛ kakra anaasɛ woyare bere a worenom aduru yi. Eyi yɛ ayaresa no fã. Nanso, ka sɛnkyerɛnne anaa ɔhaw foforo biara a wubenya ho asɛm kyerɛ wo duruyɛfo.
Dɛn ne nnuru no mu nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ aduru biara no, aldesleukin betumi de ɔhaw ahorow aba. Eyinom bi hwehwɛ sɛ wɔde wɔn kɔ ayaresabea ntɛm ara, bere a afoforo nso nyɛ aniberesɛm kɛse.
| Nneɛma bɔne a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo/ɔyarehwɛfo ntɛm ara | |
|---|---|
| Nsɛnkyerɛnne a ɛkyerɛ | Nkyerɛmu |
| Nneɛma a ɛma obi ho yɛ no hyew a emu yɛ den | Wora mu akisikuru, ɛyaw, anim, ano anaa tɛkrɛma a ɛho ahonhon. |
| Ɔhome a ɛyɛ den | Ɔhome a ɛyɛ den, nnyigyei a ɛyɛ hu a efi koko mu ba. |
| Koma mu haw ahorow | Koko mu yaw, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnyɛ daa. |
| Adwene mu nsakrae | Adwene a ɛyɛ basaa, ahomegye a enni hɔ, dadwen, nneɛma a ɛnyɛ nokware a wohu anaa ɔte (hallucinations). |
| Asaabo mu haw ahorow | Nsu a ɛtɔ so tew, nsu a ɛyɛ kɔkɔɔ tuntum anaa bruu. |
| mmerɛbo mu haw ahorow | Aniwa ne honam ani a ɛyɛ kɔkɔɔ. |
| Nsɛnkyerɛnne afoforo a anibere wom | Adwene a ɛyɛ den, nna a ɛyɛ den, mogya anaa akuru a ɛyɛ soronko, nipadua a ɛho ahonhon (titiriw anim ne anan), ɔbrɛ a ɛtra so, ɔfe, atiridiinini, atiridiinini, menewam yaw. |
| Nneɛma a mpɛn pii no ɛnyɛ aniberesɛm, nanso sɛ ɛkɔ so a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo | |
|---|---|
| Bloating (akisikuru) . | Abofono |
| Dae a ɛma obi da | Akɔnnɔ |
| Ano mu akuru | Yafunu mu yaw |
Sɛ wunya sɛnkyerɛnne foforo biara a ɛyɛ soronko a wɔanka ho asɛm wɔ saa nsɛm yi mu a, yɛsrɛ sɛ ka ho asɛm kyerɛ wo duruyɛfo anaa ɔyarehwɛfo nso.
Nkrasɛm a Wɔde Kɔ Fie
- Aldesleukin/IL-2 yɛ aduru titiriw bi a ɛboa ma wɔko tia kokoram denam w’ankasa nipadua mu ahoɔden a ɛko tia nyarewa a ɛkanyan no so, sen sɛ ebekum kokoram nkwammoaa tẽẽ.
- Wɔde saa ayaresa yi ma wɔ ayaresabea, wɔ aduruyɛfo hwɛ ase, enti ɛnsɛ sɛ wohaw wo ho wɔ dodow a wode bɛma anaasɛ wode aduru no sie ho.
- Ansa na wubefi ayaresa ase no, hwɛ hu sɛ wobɛka nyarewa foforo biara a wowɔ ne nnuru biara a worenom (a vitamin ne nhabannuru ka ho) akyerɛ wo duruyɛfo.
- Sɛ wunya ɔhaw biara a anibere wom bere a wɔreyɛ wo aduru, te sɛ atiridiinini, ahome a ɛyɛ den, wo koko mu yaw, anaa wo hohoro kɛse a, bɔ nnuruyɛfo amanneɛ ntɛm ara.
- Saa ayaresa yi betumi ayɛ den, nanso ɛnyɛ wo nkutoo. W’aduruyɛfo kuw no ayɛ krado bere nyinaa sɛ wɔbɛboa wo. Nsuro sɛ wo ne wɔn bɛkasa afa nsɛmmisa anaa dadwen biara ho.
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