Sɛ yɛte asɛmfua kokoram mpo a, yɛn nyinaa nya ehu kɛse wɔ yɛn adwene mu. Nanso ɛnnɛ, aduruyɛ ho nyansahu anya nkɔso kɛse. Wɔahu ayaresa akwan a ɛyɛ nwonwa a wɔfa so ko tia kokoram nkwammoaa. Ɛnnɛ yɛrebɛka ayaresa kwan titiriw a ɛte saa no biako ho asɛm. Sɛ yɛbɛka no tiawa a, wɔde eyinom di dwuma de sɛe kokoram akisikuru no aduannuru, kyerɛ sɛ, mogya a wɔde ma, na ɛma wɔn nyin brɛoo.
Dɛn ankasa ne saa Angiogenesis Inhibitors yi?
Sɛ yɛbɛte eyi ase a, momma yɛmfa nhwɛso ketewaa bi. Fa no sɛ, sɛ dua biara nyin kɛse a, ehia sɛ enya nsu ne aduannuru bere nyinaa. Saa ara na sɛ akisikuru betumi anyin ayɛ kɛse na atrɛw akɔ nipadua no afã afoforo a, mogya pa ho hia.
Kokoram akisikuru sua koraa mfiase no. Saa bere no, ɛtwe aduannuru a ehia fi ntini a ɛwɔ apɔwmuden a atwa ne ho ahyia no mu. Nanso sɛ akisikuru no nyin bɛyɛ milimita 1-2 a, ɛsɛ sɛ ɛyɛ n’ankasa mogya ntini nhyehyɛe foforo. Sɛnea afifide nyin nkorabata foforo no ara pɛ. Ɛyɛ mogya ntini foforo yi mu na kokoram akisikuru no ‘ma aduan’, enyin kɛse mpo, na efi ase trɛw.
Saa nnuru titiriw yi a wɔfrɛ no Angiogenesis Inhibitors , yɛ adwuma denam kokoram nkwammoaa no a esiw mogya ntini foforo a ɛmma ɛnkɔ so no so. Eyi ma kokoram nkwammoaa no nyin brɛoo, na ɛtɔ mmere bi mpo a nkwammoaa no tumi tew. Ɛwom sɛ saa ayaresa yi ntumi nsa kokoram no koraa de, nanso ebetumi asiw kokoram no nyin so na ama woatumi ne w’adɔfo atra akyɛ kakra.
Ɔkwan bɛn so na saa aduru yi yɛ adwuma?
Saa nnuru yi siw adeyɛ bi a wɔfrɛ no Angiogenesis a ɛkɔ so wɔ yɛn nipadua mu no ano. Mpɛn pii no, eyi yɛ adeyɛ a ɛho hia yiye ma yɛn nipadua. Fa no sɛ wo nsa ho apirapira. Afei saa nkwammoaa a wɔapirapira no ma sɛnkyerɛnne titiriw bi (SOS sɛnkyerɛnne) a ɛka sɛ, ‘Boa yɛn!’. Esiane saa sɛnkyerɛnne yi nti, mogya ntini foforo fi mogya ntini a atwa kuru no ho ahyia no mu, na ɛma kuru no nya mogya a ɛho hia na ɛsa.
Afei ade a enye koraa wɔ ha ne sɛ kokoram nkwammoaa nso de adeyɛ pa yi di dwuma wɔ yɛn nipadua mu ma ɛso ba wɔn mfaso. Wɔsan nso de nsɛnkyerɛnne koro no ara kɔma na wɔyɛ mogya ntini foforo de di wɔn ho aduan.
Nea Angiogenesis Inhibitors yɛ ne sɛ ɛhaw saa sɛnkyerɛnne kwan so nhyehyɛe no.
- Nsɛnkyerɛnne titiriw a ɛwɔ saa nsɛnkyerɛnne nhyehyɛe yi mu ne protein bi a wɔfrɛ no VEGF (Vascular Endothelial Growth Factor) .
- Sɛ protein yi, VEGF, kyekyere nneɛma a ɛma mogya tu wɔ nkwammoaa ani a, ɛde nkrasɛm no kɔ ma mogya ntini foforo hyehyɛ.
- Saa nnuru yi gyae adeyɛ yi wɔ akwan horow so.
| Sɛnea ɛyɛ adwuma | Nnuru ahorow ho nhwɛso ahorow |
|---|---|
| Ɛkyekyere VEGF protein no na esiw no kwan sɛ ɛnkyekyere nneɛma a ɛma nipadua no nya nkwaadɔm no. | Nnuru a wɔde ko tia nyarewa a ɛyɛ monoclonal te sɛ Bevacizumab (Avastin®). |
| Ɛsiw nsɛnkyerɛnne a efi VEGF agyefo mu no kwan tẽẽ. | Nnuru a esiw Tyrosine Kinase ano te sɛ Sorafenib (Nexavar®) ne Sunitinib (Sutent®). |
| Ɛsiw nsɛnkyerɛnne nhyehyɛe afoforo a ɛka mogya ntini a ɛba wɔ kokoram akisikuru mu no ano. | Nnuru a ɛma nipadua no tumi ko tia nyarewa te sɛ Thalidomide ne Lenalidomide (Revlimid®). |
Tebea bɛn na wɔde saa aduru yi di dwuma?
Nnuruyɛfo taa kamfo saa ayaresa yi kyerɛ kokoram a akɔ anim anaasɛ asan aba bio wɔ ayaresa akyi. Nhwɛsoɔ:
- Amemene mu kokoram
- Nufu mu kokoram
- Awotwaa mu kokoram
- Kokoram a ɛwɔ akyi berɛmo mu
- Asaabo mu kokoram
- mmerɛbo mu kokoram
- Ahurututu mu kokoram
- Lymphoma ne Multiple Myeloma
- Kokoram a ɛwɔ dwensɔtwaa mu
- Yafunu mu kokoram
- Thyroid kokoram
- Awotwaa mu kokoram
Nea ɛka ho no, wɔde saa aduru yi a wɔfrɛ no VEGF inhibitors nso sa aniwa mu nyarewa bi a mogya ntini nyin a ɛnteɛ wɔ aniwa mu de ba.
Dɛn na ɛba bere a wɔreyɛ ayaresa no?
Wɔntaa mfa nnuru yi nkutoo mma. Wɔtaa de ka kokoram ayaresa afoforo te sɛ nnuru a wɔde sa yare anaasɛ nipadua no mu tumi a ɛko tia nyarewa ho. Sɛ yɛbɛka no tiawa a, nnuru a esiw kokoram a ɛma mogya tu no ma ɔkɔm de kokoram no denam aduan a ɛmma onnya so, bere a ayaresa afoforo kunkum kokoram nkwammoaa no tẽẽ no.
Ɛdenam aduru ko a wɔde ma wo so no, wobetumi de ama wo sɛ aduru pɛnkoro anaa mprenu da biara, anaasɛ wobetumi de ahyɛ ntini mu (IV) a nkyene wom pɛnkoro nna kakraa biara.
Bere tenten a wɔde sa yare no gyina aduru ko a wɔde ma wo ne w’ayaresa tebea so. Nnipa binom kɔ so nom aduru no bere tenten a ɛyɛ adwuma no. Ɛsɛ sɛ afoforo gyae bere a wontumi nnyina nea efi mu ba no ano no. Wɔnam wo duruyɛfo a wo ne wo bɛkasa na woasusuw mfaso ne ɔhaw ahorow a ɛwɔ ayaresa no mu so na esi eyi nyinaa ho gyinae.
Asiane ne nsunsuanso bɔne bɛn na ɛwɔ mu?
Ɛho hia paa sɛ wudi kan hu asiane ne nsunsuanso bɔne a ɛwɔ aduru yi a wode bedi dwuma mu, sɛnea ɛbɛyɛ a wubetumi ahu nsakrae biara a ɛba wo nipadua mu ntɛm.
Nnuru yi mu nsunsuanso bɔne bi betumi ayɛ asiane, enti ɛho hia sɛ wuhu eyi.
| Nsunsuanso bɔne/asiane a ɛwɔ mu | Nea ɛsɛ sɛ wuhu |
|---|---|
| Mogya mmoroso | Ɛho hia sɛ wohwɛ wo mogya mmoroso daa bere a wɔreyɛ ayaresa no. |
| Mogya a ɛtɔ gu nipadua no mu | Hwɛ yiye wɔ sɛnkyerɛnne ahorow te sɛ nipadua no baabiara a akuru ne mogya a ɛwɔ nsu mu no ho. |
| Akuru a ɛkyɛ | Oduruyɛfo no hwɛ yiye titiriw wɔ nnuru yi a ɔde bɛma ansa na wɔayɛ oprehyɛn anaa bere a wɔayɛ no oprehyɛn akyi no ho. |
| Yafunu mu a ɛyɛ tokuru | Ɛwom sɛ eyi ntaa nsi koraa de, nanso sɛ wo yafunu mu yɛ wo yaw mpofirim a, bɔ wo duruyɛfo amanneɛ ntɛm ara. |
| Mogya a ɛtwetwe | Eyi yɛ tebea a ɛyɛ hu yiye na ebetumi de tebea horow te sɛ komayare anaa akisikuru aba. |
| Nneɛma afoforo a ɛde ba | Thyroid dwumadi a ɛso tew ne mmerɛbo a asɛe nso betumi aba. |
Ebia eyinom bɛyɛ te sɛ nea ɛyɛ hu, nanso wo duruyɛfo bɛhwɛ w’akwahosan ne wo mogya mu nhwehwɛmu bere nyinaa, enti wobetumi ahu asiane ahorow yi na wɔadi ho dwuma kɛse.
Mɛyɛ dɛn ahwɛ me ho? Bere bɛn na ɛsɛ sɛ mefrɛ oduruyɛfo no?
Ade a ɛho hia sen biara a wubetumi ayɛ ne sɛ wubehu nneɛma bɔne a ebetumi afi mu aba no yiye ansa na woafi aduru yi ase. Afei, sɛ wuhu nsakrae bi wɔ wo nipadua mu a, wubetumi ahu ntɛm ara na woaka akyerɛ wo duruyɛfo. Wo duruyɛfo betumi ama wo nnuru afoforo a wode besiw saa nsunsuanso bɔne no so, anaasɛ ɔbɛsesa nnuru a worenom no dodow.
Sɛ wuhu yare no ho sɛnkyerɛnne biara a ɛyɛ soronko mpofirim a, hwehwɛ ayaresa ntɛm ara. Titiriw sɛ wuhu sɛnkyerɛnne ahorow a ɛkyerɛ sɛ woayɛ akisikuru anaa komayare (e.g., wo koko mu yaw kɛse, ɛyɛ den sɛ wobɛhome, w’anim anaa wo ntini a ɛyɛ mmerɛw) a, kɔ ayaresabea a ɛbɛn wo no Dwumadibea a Ɛhwɛ Ntɛmntɛm (ETU) ntɛm ara.
So nneɛma bi wɔ hɔ a efi awosu mu ma saa adeyɛ yi gyae?
Yiw, nneɛma bi wɔ nnuan bi mu a ebetumi asiw nsɛnkyerɛnne a ɛka ho wɔ saa ntini a ɛma mogya tu yi mu no bi kwan. Wɔtaa hu saa nnuan yi wɔ Mediterraneafo aduan mu. Nhwɛsoɔ:
- Green tii a wɔde yɛ aduan
- Ngodua ngo
- Bobe kɔkɔɔ
- Atoko a wɔde yɛ atoko
- Asparagus a wɔde yɛ aduan
Nnuruyɛfo de abɔde mu nneɛma yi reyɛ nnuru foforo ho nhwehwɛmu, nanso saa nhwehwɛmu no da so ara wɔ ne mfiase.
Ɛho hia sɛ wokae biribi a ɛho hia wɔ ha. Saa nnuan yi a wobedi no rensa kokoram anaasɛ ɛremma kokoram akisikuru no nnyin. Eyinom nyɛ nea wɔde besi kokoram nnuru a oduruyɛfo akyerɛw ama obi ananmu da.
Nanso, aduan a ahoɔden wom a obi di no betumi aboa kɛse ma obi a ɔrefa kokoram ayaresa mu no akɔ so ayɛ den. Enti, hwɛ hu sɛ wubedi aduan a ɛkari pɛ.
Nkrasɛm a Wɔde Kɔ Fie
- Angiogenesis inhibitors yɛ aduru bi a esiw mogya ntini a ɛde mogya kɔ kokoram akisikuru mu no ano, na ɛhwɛ wɔn nyin so.
- Ɛwom sɛ eyinom ntumi nsa kokoram koraa de, nanso ebetumi aboa ma wɔadi yare no nkɔso so na ama nkwa nna akyɛ.
- Mpɛn pii no, wɔde nnuru yi ka ayaresa afoforo te sɛ nnuru a wɔde sa yare ho.
- Esiane sɛ nneɛma bɔne a ɛyɛ hu te sɛ mogya mmoroso ne mogya a ɛtɔ gu nipadua mu betumi aba nti, ka sɛnkyerɛnne biara a ɛyɛ soronko a ɛba bere a wɔreyɛ ayaresa no ho asɛm kyerɛ wo duruyɛfo ntɛm ara.
- Mfa abɔde mu nnuan a wɔde ka ho nni dwuma da sɛ nea wode besi aduruyɛ ananmu. Di wo duruyɛfo afotu akyi bere nyinaa.
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