Momma yɛnhwehwɛ ammonia dodow a ɛwɔ wo mu no ho asɛm. So eyi betumi ayɛ nea asiane wom?

Nneɛma pii kɔ so wɔ yɛn nipadua mu, ɛnte saa? Nneɛma a yedi ne nea yɛnom no yam, ahoɔden ba, na nwura nso ba. Enti, saa ammonia yi yɛ nwura a ɛte saa no mu biako a ɛba yɛn nipadua mu. Nanso sɛ wɔannyi eyi afi mu yiye a, ebetumi de ɔhaw ahorow bi aba. Ɛnnɛ, momma yɛnka ammonia yi ho asɛm, nea enti a ebetumi ayɛ asiane, ne sɛnea wobedi so.

Dɛn ne ammonia? Sɛ yɛbɛka no tiawa a...

Sɛ yɛbɛka no tiawa a, ammonia, anaa (NH3), yɛ nwura a mmoawa a wɔwɔ yɛn dwensɔtwaa mu yɛ bere a yɛyam protein a yedi no. Fa no sɛ biribi a aka wɔ aduan a wɔyam mu. Enti, wunim nea ɛtaa si? Saa ammonia yi kɔ yɛn mmerɛbo mu . Mmɛn te sɛ adwumayɛbea a ɛyɛ nwonwa wɔ yɛn nipadua mu. Ɛhɔ no, wɔyɛ ammonia yi ho adwuma na wɔdan no nwura foforo a wɔfrɛ no urea . Afei, saa urea yi kɔ yɛn asaabo mu , baabi a ɛkɔ nsu mu. Wɔfrɛ saa adeyɛ yi nyinaa urea kyinhyia .

Nanso, susuw ho sɛ ɔhaw bi wɔ urea kyinhyia yi fã biara mu, sɛ́ ɛyɛ mmerɛbo, asaabo, anaa biribi foforo a ɛboa saa adeyɛ yi a, ɛnde wɔnyɛ ammonia no ho adwuma yiye na wɔayi afi mu. Sɛ ɛba saa a, ammonia no fi ase boaboa ano wɔ mogya no mu. Sɛ ɛboaboa ano pɛ a, ebetumi nso afi mogya no mu akɔ amemene no mu. Ammonia dodow a ɛsɛ sɛ ɛwɔ yɛn mogya mu no sua koraa . Sɛ ɛkɔ soro kakra mpo, kyerɛ sɛ, sɛ tebea bi a wɔfrɛ no hyperammonemia ba a, ɛyɛ awuduru kɛse ma yɛn ntini a ɛwɔ mfinimfini (CNS). Ɛne sɛ, asiane wom.

Ɛsɛ sɛ ammonia dodow ahe na ɛwɔ nipadua no mu?

Afei, ammonia dodow a ɛsɛ sɛ ɛwɔ obi a ɔwɔ apɔwmuden mogya mu no gu ahorow bere a mfe a obi nyin no. Nkokoaa a wɔawo wɔn foforo no dɔɔso kakra sen mpanyimfo. Afei nso, sɛ́ ebia wɔwoo akokoaa no wɔ ne bere mu anaasɛ ntɛm nso ka no.

• Nkokoaa a wɔawo wɔn a wɔwɔ apɔwmuden : Bɛyɛ 45±9 micromoles wɔ lita biara mu / micromol/L. Mpɛn pii no, anohyeto a ɛwɔ soro no yɛ 80 kosi 90 micromol/L.
• Nkokoaa a wɔawo wɔn ansa na bere aso : Bɛyɛ 71±26 micromol/L. Eyi so tew kodu sɛnea ɛte daa wɔ bɛyɛ nnanson akyi.
• Mmofra a wɔadi boro ɔsram biako : Ennu 50 micromol/L.
• Mpanyimfo : Ennu 30 micromol/L.

Nanso ade biako a ɛsɛ sɛ yɛma ɛtra yɛn adwenem. Saa gyinapɛn ahorow yi betumi ayɛ soronko kakra wɔ lab biara mu. Enti, ɛbɛyɛ papa sɛ wode bɛtoto gyinapɛn ahorow a ɛwɔ wo lab amanneɛbɔ mu no ho. Sɛ ɔhaw bi wɔ hɔ a, .Hwɛ hu sɛ wubebisa wo duruyɛfo anaa ɔyarehwɛfo.

Ammonia dodow a ɛkɔ soro no yɛ nea asiane wom dɛn?

Ammonia yɛ ade a awuduru wom kɛse . Mpɛn pii no, ammonia dodow a ɛwɔ ɔpanyin a ɔwɔ apɔwmuden mogya mu no nnu micromoles 50 wɔ lita biara mu (micromol/L). Nanso, sɛ eyi kɔ soro kodu micromoles 100 pɛ wɔ lita biara mu (100 micromol/L) mpo a, nsakrae betumi afi ase aba wɔ n’adwene mu. Eyi kyerɛ sɛ ɛbɛyɛ den sɛ wode w’adwene besi biribi so, na ebia w’adwene betu afra kakra. Sɛ ammonia dodow a ɛwɔ mogya no mu no kɔ soro kodu 200 micromol/L a, ebia wobɛkɔ koma mu na wo ho popo. Eyi yɛ asiane kɛse na ebetumi de nkwa ato asiane mu.

Ɔkwan bɛn so na wɔbɛhwɛ sɛnea ammonia dodow wɔ nipadua no mu?

Wo duruyɛfo betumi de mogya mu nhwehwɛmu asusuw wo ammonia dodow . Wɔ mpanyimfo fam no, wɔtaa yɛ eyi denam mogya kakraa bi a wogye fi ntini bi a ɛwɔ wo nsa mu no so. Wɔ mmofra a wɔawo wɔn foforo fam no, oduruyɛfo bɛhohoro akokoaa no nan ase, de ade ketewaa bi abɔ no, na wagye mogya kakraa bi. Afei, wɔde aduru ketewaa bi a wɔde kyekyere baabi no gu baabi. Eyi te sɛ mogya mu nhwehwɛmu a wɔyɛ no daa ara pɛ.

Dɛn ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ ammonia dɔɔso?

Sɛ ammonia dodow a ɛwɔ wo mogya mu no kɔ soro a, ebia wubehu sɛnkyerɛnne ahorow te sɛ:

• Adwene a ɛyɛ basaa ne adwene a ɛyɛ basaa
• Dae a ɛtra so, ɛyɛ den sɛ wobɛsɔre
• Nsakrae a ɛba n’adwene mu, ɛtɔ mmere bi mpo a nhumu a ɛyera
• Adwene a ɛsakra, abufuw, ne adwene a ɛsakra
• Nsa a ɛwosow, titiriw bere a woretrɛw wo nsa no mu akɔ w’anim no
• Coma - Tebea a obi ntumi nhu hwee na ontumi nyɛ hwee

Eyi ho hia yiye: sɛ wo anaa obi a ɔbɛn wo wɔ saa sɛnkyerɛnne ahorow yi a, nsɛe bere na frɛ ambulance adwumayɛbea 1990, anaa kɔ ayaresabea a ɛbɛn wo no dwumadibea a wɔhwɛ ntɛmpɛ so ntɛm ara sɛnea wubetumi. Ammonia dodow a ɛkɔ soro no betumi de nkwa ato asiane mu, enti ɛho hia sɛ wɔkɔ ayaresabea ntɛm ara.

Akokoaa a wɔawo no foforo ho sɛnkyerɛnne

Sɛ akokoaa a wɔawo no foforo da saa sɛnkyerɛnne ahorow yi bi adi wɔ awo akyi nna kakraa a edi kan no mu a, oduruyɛfo betumi asɔ ammonia dodow ahwɛ:

• Ahomegye a enni hɔ bere nyinaa, su a wɔtaa su, ne ɔpɛ a wonni sɛ wɔbɛnom nufusu (Irritability) .
• Ɔfe a wɔfe
• Dae, ɔbrɛ, ɛyɛ den sɛ wobɛsɔre
• Akisikuru a ɛma obi ho kyere no

Sɛ akokoaa bi wɔ saa sɛnkyerɛnne ahorow yi a, mmu w’ani ngu so. Kɔ oduruyɛfo nkyɛn ntɛm ara.

Dɛn nti na ammonia dodow a ɛwɔ nipadua no mu no kɔ soro saa?

Nneɛma pii nti na ammonia dodow a ɛwɔ mogya no mu betumi akɔ soro. Momma yɛnhwɛ nea wɔyɛ:

• Mmɛn mu yare: .Eyi ne ade titiriw nti a ɛte saa . Sɛ wo mmerɛbo no asɛe, te sɛ nea ɛwɔ mmerɛbo mu a, mmerɛbo no ntumi nyi ammonia no mfi hɔ yiye. Eyi taa ba wɔ mmerɛbo mu yare a emu yɛ den ho. Nanso, ɛtɔ mmere bi a, sɛ mmerɛbo mu yare no mu yɛ den mpo a, sɛ biribi si wɔ yafunu anaa dwensɔtwaa mu, te sɛ yafunu mu mogya, anaasɛ anyinam ahoɔden a ɛnkari pɛ a, ammonia dodow betumi akɔ soro mpofirim.

• Mogya a ɛkɔ mmerɛbo no mu a ɛso tew: Sɛ mmerɛbo no nnya mogya a ɛdɔɔso a, ammonia nni ɔkwan biara a ɛbɛfa so akɔ mmerɛbo no mu na ɛho tew. Afei, ammonia boaboa ano wɔ mogya no mu.

• Hepatic encephalopathy: Eyi yɛ nea ɛyɛ den kakra. Sɛ yɛbɛka no tiawa a, sɛ mmerɛbo no yare anaa asɛe na entumi nyi ammonia mfi hɔ yiye a, ammonia boaboa ano wɔ mogya no mu na ɛkɔ amemene no mu. Eyi betumi ama adwene atu afra, adwene atu afra, na wakɔda. Ɛtɔ mmere bi a, ebetumi akum obi.

• Reye yare: Eyi yɛ tebea a ɛntaa nsi nanso emu yɛ den yiye a ɛka mogya, amemene, ne mmerɛbo. Mpɛn pii no ɛma mogya mu ammonia dodow kɔ soro na ɛma mogya mu glucose dodow so tew. Ɛtaa ba mmofra ne mpanyimfo nkumaa a wɔanom aspirin de anya yare no ho sɛnkyerɛnne bere a wɔrenya ahoɔden afi ɔyare mmoawa te sɛ akisikuru anaa atiridiinini (atiridii) mu no so. Wonnim nea ɛde Reye yare no ba ankasa. Nanso, esiane asiane yi nti, ɛnsɛ sɛ mmofra ne mpanyimfo nkumaa nom aspirin gye sɛ oduruyɛfo kamfo kyerɛ wɔn pɔtee.

• Asaabo / adwene mu yareɛ: Sɛ w’asaabo ntumi nyɛ adwuma yie, a ɛkyerɛ sɛ ɛreyɛ adwuma yie a, ɛntumi nyi urea mfi hɔ yie. Eyi ma ammonia boaboa ano wɔ mogya no mu.

• Awosu mu nyarewa a ɛwɔ urea kyinhyia no mu: Awosu mu nyarewa a wɔntaa nhu koraa wɔ hɔ. Eyinom fi enzyme ahorow a ɛho hia ma urea kyinhyia no biako a enni awosu mu. Wɔtaa hu eyi wɔ awo mu.

• Hemolytic disease of the newborn: Eyi ba bere a ɛna a onyinsɛn yɛ nnuru a ɛko tia ne ba mogya mu nkwammoaa no. Wobetumi asiw tebea yi ano. Sɛ wo nni Rh-negative na wonnya nyɛɛ wo nkate dedaw a, wubetumi anom aduru bi a esiw wo antibodies no kwan sɛ ɛne wo ba no Rh-positive nkwammoaa no nyɛ adwuma.

Dɛn ne ayaresa ahorow a wɔde sa ammonia dodow a ɛkɔ soro?

Ayaresa a wɔde sa ammonia dodow a ɛkɔ soro no gyina nea ɛde ba no so. Sɛ nhwɛso no, wɔ ɔpanyin mu no, ebetumi afi mmerɛbo mu yare anaa mmerɛbo mu amemene mu yare, bere a wɔ abofra a wɔawo no foforo mu no, ebetumi afi awo mu tebea bi a ɛsɛe urea kyinhyia no.

Sɛ wɔresa acute hyperammonemia a, nea wɔde wɔn adwene si so titiriw ne ammonia dodow a wɔbɛtew so na wɔadi nsɛnnennen te sɛ amemene mu edema ne intracranial hypertension so.

Sɛ abofra a wɔawo no foforo ammonia dodow kɔ soro a, nnuruyɛfo gyae protein a wɔde ma no (efisɛ bere a wɔayam protein no na wonya ammonia). Mmom no, wɔma wɔn glucose ano aduru na ama wɔanya ahoɔden. Wɔde aduru bi a wɔfrɛ no hemodialysis nso di dwuma de yi ammonia fi akokoaa no mogya mu. Nea ɛka eyi ho ne sɛ wɔde afiri titiriw bi a wɔfrɛ no dialysis afiri ne afiri a wɔde yiyi mogya mu te sɛ asaabo a wɔde nsa ayɛ bɛhohoro mogya no ho .

Sɛ wɔresa mmerɛbo mu amemene mu yare a, botae no ne sɛ wɔbɛtew ammonia a ɛba dwensɔtwaa mu no so. Ayaresa a edi kan ne nnuru a wɔnom a wɔfrɛ no lactulose ne lactitol . Saa asikre ahorow yi brɛ ammonia a ɛba dwensɔtwaa mu no ase na ɛtwetwe.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn fa me ammonia dodow ho asɛm?

Eyi da adi pefee. Sɛ wo anaa obi a ɔbɛn wo rehu sɛnkyerɛnne ahorow a ɛkyerɛ sɛ ammonia dɔɔso wɔ mogya mu, te sɛ adwene a ɛyɛ basaa a yɛadi kan kaa ho asɛm no, nna a ɔdae bere nyinaa, ne nsakrae a ɛba w’adwene mu a, frɛ 911 ntɛm ara, anaa kɔ ayaresabea dan a ɛbɛn wo a wɔhwɛ ntɛmpɛ so ntɛm ara sɛnea wubetumi. Eyi nyɛ biribi a ɛsɛ sɛ wɔtwentwɛn so.

Sɛ wowɔ mmerɛbo mu yare a, ɛsɛ sɛ wokɔ wo duruyɛfo nkyɛn daa na ama woahwɛ ahu sɛ wo mmerɛbo no retu ammonia yiye. Eyi bɛboa wo ma woahu ɔhaw biara ntɛm.

Enti, nneɛma bɛn na ɛho hia paa a ɛsɛ sɛ yɛkae fi saa asɛm yi mu?

Ɛwom sɛ ɛyɛ ade a ɛfata sɛ yɛn nipadua yɛ ammonia sɛ ade a wɔsɛe no de, nanso sɛ ɛboaboa ano wɔ mogya no mu boro so a, ebetumi ayɛ asiane kɛse.

Sɛ wo anaa obi a ɔbɛn wo wɔ ammonia dodow a ɛdɔɔso ho sɛnkyerɛnne ahorow (sɛ nhwɛso no, adwene a ɛyɛ basaa, nna a ɛtra so, suban mu nsakrae) a, kɔ ayaresabea a ɛbɛn wo ntɛm ara a wontwentwɛn wo nan ase. Eyi betumi ayɛ nkwa anaa owu tebea.

Ɛho hia titiriw sɛ wuhu saa sɛnkyerɛnne ahorow yi sɛ wowɔ mmerɛbo mu yare a, efisɛ eyi betumi ama asiane a ɛwɔ hɔ sɛ ammonia dodow bɛkɔ soro no ayɛ kɛse.

Sɛ wowɔ nsɛmmisa bi fa asiane a ɛwɔ ammonia dodow a ɛkɔ soro mu, anaa biribi foforo biara a wopɛ sɛ wuhu ho a, ntwentwɛn wo nan ase sɛ wo ne wo duruyɛfo bɛkasa. Wɔwɔ hɔ sɛ wɔbɛboa wo na wɔabua wo nsɛmmisa. Apɔwmuden a wobɛkɔ so atra hɔ no ne ade a ɛho hia sen biara!

` Ammonia, Ammonia dodow, Mmerɛbo, Asaabo, Urea Kyinhyia, Mmenewa mu Mmene mu Yare, Reye Yare, Mogya mu Nhwehwɛmu, Hyperammonemia