Sɛ nnuruyɛfo hu sɛ wo anaa obi a ɔbɛn wo anya kokoram a, ɛtaa ba sɛ w’adwene tu fra na wosuro mpo wɔ ayaresa a wubetumi apaw ho. Ɛnnɛ, yɛrebɛka aduru bi a ɛyɛ soronko kakra a wɔfrɛ no Avelumab a wɔde sa kokoram ahorow pii ho asɛm. Momma yɛnka nsɛmpɔw ne nneɛma a ɛsɛ sɛ wuhu fa aduru yi ho ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw na emu da hɔ so.
Dɛn ne aduru yi a wɔfrɛ no Avelumab?
Sɛ yɛbɛka no tiawa a, Avelumab (ahyɛnsode: BAVENCIO) yɛ nnuru a wɔde bɔ nkurɔfo ho ban a ɛka nnuru soronko bi a wɔfrɛ no monoclonal antibodies ho . Fa no sɛ ɔsraani a wɔatete no a ɔboa yɛn nipadua no ankasa nipadua mu ahoɔden a ɛko tia nyarewa no. Nea saa aduru yi yɛ ne sɛ ɛboa yɛn nipadua mu tumi a ɛko tia nyarewa no ma wohu kokoram nkwammoaa, tow hyɛ wɔn so, na ɛsɛe wɔn.
Wɔde saa aduru yi sa kokoram ahorow abiɛsa titiriw:
- Merkel cell carcinoma: Eyi yɛ honam ani kokoram a ɛntaa nsi nanso ɛtrɛw ntɛmntɛm.
- Renal cell cancer: Eyi yɛ kokoram bi a ɛba asaabo mu.
- Urothelial cancer: Kokoram bi a ɛba akisikuru anaa akisikuru no afã afoforo.
Nea ɛka eyi ho no, ebia wo duruyɛfo nso bɛkyerɛw saa aduru yi ama ayaresa tebea afoforo. Sɛ wowɔ nsɛmmisa bi fa ho a, bisa wo duruyɛfo.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ayaresa ase
Eyi ho hia paa. Ansa na wubefi ase de Avelumab ayaresa no, ɛho hia sɛ woka w’akwahosan ho abakɔsɛm nyinaa kyerɛ wo duruyɛfo. Mfa biribiara nsie. Hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ tebea horow a edidi so yi mu biara a.
- Sɛ wowɔ yare bi a nipadua no tumi ko tia nyarewa a: Sɛ yɛbɛka no tiawa a, eyi yɛ yare a nipadua no mu nkwammoaa a ɛko tia nyarewa no tow hyɛ nipadua no ankasa nkwammoaa a ɛte apɔw so. Sɛ nhwɛso no, nyarewa te sɛ Crohn yare, ulcerative colitis, anaa lupus.
- Sɛ woayɛ anaasɛ woreyɛ nhyehyɛe sɛ wobɛma stem cell transplant: titiriw allogeneic stem cell transplant.
- Sɛ wowɔ komayare, mogya mmoroso, anaa mogya mu srade a ɛkɔ soro a.
- Sɛ abakɔsɛm bi wɔ hɔ a ɛfa akwaa a wɔde si ananmu ho a.
- Sɛ wowɔ nyarewa a ɛfa ntini nhyehyɛe ho a: Sɛ nhwɛso no, tebea horow te sɛ `myasthenia gravis` anaa `Guillain-Barre syndrome`.
- Sɛ woanya avelumab anaa aduru foforo biara, aduan, anaa ade a wɔde yɛ ade a.
- Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaasɛ worema nufu a: Eyi ho hia yiye.
Mɛyɛ dɛn ama wo aduru yi?
Eyi nyɛ aduru a wubetumi de akɔ fie. Avelumab yɛ aduru a wɔde twitwiw wo nipadua mu nkakrankakra denam ntini bi mu (wɔde gu ntini mu) . Ɛte sɛ nea wɔde nkyene rema wo. Wɔde saa ayaresa yi ma wɔ ayaresabea anaa ayaresabea, a oduruyɛfo anaa ayarehwɛfo a wɔatete wɔn hwɛ so yiye .
Ansa na wɔbɛyɛ ayaresa biara no, wɔbɛma wo nsɛm kratasin titiriw bi (MedGuide) a ɛfa saa aduru yi ho. Ɛho hia sɛ wokenkan na wote ase yiye bere biara.
Na sɛ wonom nnuru pii nso ɛ? (Nneɛma a wɔde ma boro so) .
Wɔde eyi ma wɔ ayaresabea tebea mu enti hokwan a ɛwɔ hɔ sɛ eyi bɛba no sua koraa. Nanso, sɛ wususuw sɛ woanom aduru yi dodo a, ka kyerɛ nnuruyɛfo no ntɛm ara. Sɛ ɛnte saa a, frɛ National Poisons Information Center a ɛwɔ Colombo National Hospital , anaa kɔ Emergency Treatment Unit (ETU) a ɛwɔ ayaresabea a ɛbɛn wo no.
Nneɛma a ɛsɛ sɛ wususuw ho bere a wɔreyɛ ayaresa no
Wo duruyɛfo bɛhwɛ wo yiye wɔ w’ayaresa no nyinaa mu, na ɛda adi sɛ ɛho behia sɛ woyɛ mogya mu nhwehwɛmu daa de hwɛ sɛnea ayaresa no de ba ne ɔhaw biara a ebefi mu aba no.
Hwɛ yiye titiriw bere a wonyinsɛn ne bere a worema nufu no!
Eyi yɛ asɛm a ɛho hia paa.
- Kwati sɛ wubenyinsɛn koraa bere a worenom aduru yi ne anyɛ yiye koraa no ɔsram biako bere a woagyae ayaresa no. Ɛsɛ sɛ mmea hwɛ yiye titiriw wɔ eyi ho, efisɛ saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu kɛse.
- Afei nso, kwati sɛ wobɛma wo ba no nufu bere a worenom aduru yi ne anyɛ yiye koraa no ɔsram biako wɔ dodow a etwa to no akyi.
Sɛ wowɔ nsɛmmisa bi fa eyi ho a, ntwentwɛn wo nan ase sɛ wo ne wo duruyɛfo bɛkasa.
Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ aduru biara no, Avelumab betumi de ɔhaw ahorow aba. Nanso, ɛnyɛ obiara na onya bi. Nsunsuanso bɔne bi betumi ayɛ aniberesɛm, enti ɛho hia sɛ wohwɛ so yiye. Momma yɛnte eyinom ase yiye wɔ pon a ɛwɔ ase ha no so.
| Nsunsuanso bɔne no su | Esu |
|---|---|
| Nneɛma bɔne a anibere wom a ɛsɛ sɛ wobɔ wo duruyɛfo anaa ayarehwɛfo amanneɛ ntɛm ara | |
| Nneɛma a ɛma obi ho yɛ no hyew ne ɔhaw ahorow a ɛma nipadua no tumi ko tia nyarewa | Ɔhome a ɛyɛ den, koko a ɛyɛ den, nipadua mu yaw, atiridiinini, awɔw a wɔte nka, honam ani kɔkɔɔ, akisikuru (ebetumi nso aba ano mu), nkwaa mu yaw, ɔbrɛ a ɛtra so. |
| Nnuan a wɔyam no mu haw ahorow | Yafunu mu yaw, akisikuru a emu yɛ den (mogya anaa nsu), akisikuru, nsu tuntum anaa tarry, akisikuru, ɔfe. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ asaabo asɛe | Nsu dodow a ɛba no so tew anaasɛ ɛsakra, ɛyɛ den sɛ wobɛtow nsu, anan anaa anansoaa a ɛho ahonhon. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ mmerɛbo asɛe | Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum, aniwa anaa honam ani yɛ kɔkɔɔ, yafunu no atifi nifa so ɛyaw, aduan ho akɔnnɔ a ɛyera, na ɔte nka sɛ wayɛ mmerɛw. |
| Nsɛnkyerɛnne afoforo a anibere wom | Akyi yaw, aniwa a ɛsakra, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ, ɔtopae, fifiri a ɛboro so, mu duru a ɛso tew, ti nhwi a ɛso tew, ɔkɔm anaa sukɔm a ɛboro so. |
| Nsunsuanso bɔne a mpɛn pii no ɛnyɛ aniberesɛm, nanso sɛ ɛkɔ so a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo | |
| Apirakuru nketenkete | Tiyɛ, nnompe mu yaw, ntini mu yaw, aduan ho akɔnnɔ a ɛyera. |
Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhyia biribi soronko bi a, yɛsrɛ wo ka kyerɛ wo duruyɛfo.
Nkrasɛm a Wɔde Kɔ Fie
- Avelumab yɛ aduru titiriw bi a ɛkanyan yɛn nipadua mu ahoɔden a ɛko tia nyarewa na wɔde ma kokoram ahorow pii.
- Ansa na wubefi ayaresa ase no, ka w’ayaresa tebea, nnuru a wonom, ne nneɛma a ɛma wo ho yɛ wo hyew nyinaa kyerɛ wo duruyɛfo a wunsie biribiara.
- Ɛho hia koraa sɛ wobɛkwati nyinsɛn ne nufu a wobɛma bere a worenom aduru yi ne anyɛ yiye koraa no ɔsram biako bere a woagyae no.
- Sɛ wunya ɔhaw biara a anibere wom te sɛ ahome a ɛyɛ den, honam ani akisikuru, akisikuru a emu yɛ den, anaa aniwa a ɛyɛ kɔkɔɔ a, hwehwɛ ayaresa ntɛm ara.
- Mma wo duruyɛfo a wobɛkɔ akɔhwɛ wo no nmpa wo ti so. Sɛ wuntumi nkɔ a, di kan ma wɔnhu na yɛ nhyehyɛe foforo.
- Ɛyɛ wo hokwan sɛ wo ne wo duruyɛfo bɛkasa pefee wɔ nsɛmmisa anaa nsɛm biara a ɛhaw wo ho.
👩🏽 ⚕️ Nsɛmmisa foforo (FAQs)
💬 Dɛn na wɔde Felodipine / Plendil aduru di dwuma?
Eyi yɛ mogya mmoroso aduru a etu mpɔn kɛse na ahoɔden wom (Calcium Channel Blocker - CCB) wɔ wiase, a wɔayɛ sɛ ɛbɛhyɛ ‘mogya mmoroso a emu yɛ den’ ano! Wɔayɛ saa aduru yi sɛ ɛbɛtwetwe brɛoo paa (Extended-release), enti ɛma nhyɛso no yɛ ketewaa da mũ no nyinaa ( nnɔnhwerew 24).
💬 Sɛ yɛnom saa mogya mmoroso aduru (Felodipine) yi a, ɛma yɛn mogya so tew ntɛm ara?
Sɛ mogya ntini bi bɛtwetwe/atwetwe na nhyɛso no akɔ soro a, akyinnye biara nni ho sɛ ɛsɛ sɛ ‘Calcium’ nketenkete no hyɛn mogya ntini no mu! Sɛ saa aduru yi hyɛn mogya no mu ara pɛ a, calcium apon (L-type calcium channels) a ɛwɔ saa mogya ntini no mu nyinaa siw/toto mu 100% na wɔto mu. Esiane sɛ calcium nkɔ mu nti, mogya ntini no ntumi ntwitwiw na ɛyɛ mmerɛw kɛse (Vasodilation). Afei, mogya sen ntɛmntɛm te sɛ asubɔnten na nhyɛso no so tew.
💬 Nsunsuansoɔ bɛn na ɛyɛ ahometew a ɛwɔ saa aduru yi (Felodipine) a wɔnom mu? Dɛn nti na wɔka sɛ ɛnsɛ sɛ wodi bobe aba?
Ɔhaw kɛse ne sɛ ɛnsɛ sɛ wonom ‘Grapefruit/Grapefruit juice (akutu a ɛyɛ dɛ bi)’ da bere a worenom saa aduru yi! Sɛ wonom a, aduru no a ɛtwetwe kɔ nipadua no mu no bɛkɔ soro wɔ ɔkwan a ɛnteɛ so 100% na awiei koraa no nhyɛso no betumi akɔ fam na wubetumi ahwe ase (CYP3A4 Inhibition)! Nneɛma afoforo a ɛhyɛ abufuw kɛse ne sɛ akyinnye biara nni ho sɛ eyi bɛma ‘Swelling of the ankles/legs (Peripheral Edema)’ na koma abɔ ntɛmntɛm/ayɛ kɔkɔɔ (Flushing).
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