Dɛn ne Burkitt Lymphoma? Momma yɛnka ho asɛm tiawa!

Ebia woahu sɛ yafunu mu ayɛ wo yaw wɔ wo ba ketewa no mu, anaasɛ akisikuru bi wɔ ne kɔn anaa ne nsateaa mu, na ebia na ɛhaw wo kakra. Mpɛn pii no, eyinom yɛ ade a ɛfata. Nanso, kokoram bi wɔ hɔ a ɛntaa nsi koraa a ebetumi atrɛw ntɛmntɛm wɔ nipadua no mu nyinaa . Ɛno na yɛrebɛka ho asɛm nnɛ. Wɔfrɛ no Burkitt Lymphoma. Mma wo ho nnsuro bere a wote din no, efisɛ nea ɛho hia sen biara ne sɛ wubehu ho nsɛm yiye.

Dɛn ankasa ne Burkitt Lymphoma?

Sɛ yɛbɛka no tiawa a, Burkitt lymphoma yɛ kokoram a enyin ntɛmntɛm yiye a ɛba B-cells , mogya mu nkwammoaa fitaa bi a ɛwɔ yɛn nipadua mu no mu. Ɛka kokoram kuw a wɔfrɛ no lymphoma ho, na ɛyɛ kokoram bi a ɛnyɛ Hodgkin lymphoma . Wɔtaa hu no wɔ mmofra nkumaa ne mpanyimfo nkumaa mu. Nnipa binom nso frɛ no Burkitt yare, Burkitt lymphoma, anaa Burkitt akisikuru.

Mpɛn pii no efi ase wɔ ntini a ɛwɔ wo yafunu anaa wo hwene mu no mu. Nanso ebetumi atrɛw ntɛmntɛm akɔ wo nipadua no afã afoforo te sɛ:

• Yafunu (yafunu no fã) .
• Nnompe mu ntini
• Yafunu mu ntini a ɛwɔ yafunu mu
• Jaw mpɔtam hɔ
• Akisikuru a ɛwɔ akyi
• Menem
• Tonsil ntini ahorow

Esiane sɛ ɛkɔ so ntɛmntɛm nti, ɛtɔ mmere bi a ebetumi de nkwa ato asiane mu. Nanso nea eye sen biara ne sɛ sɛ wofi ase sa yare ntɛm a, wobetumi asa nnipa dodow no ara yare koraa . Ɛno kyerɛ sɛ sɛnkyerɛnne no kɔ na wubetumi akɔ so anya apɔwmuden a ɛrensan mma bio. Yɛfrɛ eyi kɔ `bere tenten fafiri`.

Burkitt Lymphoma ahorow atitiriw bɛn na ɛwɔ hɔ?

Eyi yɛ ahorow atitiriw abiɛsa:

1. Endemic type: Eyi abu so kɛse wɔ Afrika mmeae bi. Wɔahu sɛ ɛne mmoawa bi a wɔfrɛ no Epstein-Barr mmoawa (EBV) wɔ abusuabɔ .

2. Sporadic type: Wohu eyi wɔ aman te sɛ United States mu, titiriw wɔ mmofra nkumaa mu. Saa ɔkwan yi na ɛma mogya a ɛnyɛ Hodgkin lymphoma bɛboro 40% ba mmofra mu.

3. Ɛfa nipadua no mu tumi a ɛko tia nyarewa ho: Eyi ba nnipa a wɔn nipadua mu tumi a ɛko tia nyarewa no ayɛ mmerɛw, esiane nyarewa te sɛ HIV/AIDS anaa nneɛma afoforo nti.

Eyi abu so dɛn? Hena na ɔtaa nya bi?

Burkitt lymphoma yɛ kokoram a ɛntaa nsi ankasa. Sɛ nhwɛso no, wɔ United States no, nea ɛba bere ne bere mu no ba mmofra ɔpepem biara a wonnii mfe 16 biara mu bɛyɛ baanan mu.Ɛyɛ mogya mu nkwammoaa a ɛma mogya tu nyinaa mu 1% kosi 2% wɔ mpanyimfo mu.

Eyi taa ba mmofra nkumaa mu kɛse , a mpɛn pii no wɔadi fi mfe 3 kosi 12.

Dɛn ne sɛnkyerɛnne ahorow no? Wobɛyɛ dɛn ahu eyi?

Nsɛnkyerɛnne betumi ada adi mpofirim. Nea ɛka ho ne:

• Yafunu mu yaw, akisikuru, ɔfe
• Atiridiinini, adwenemhaw, fifiri a ɛba anadwo
• Aduan ho akɔnnɔ a ɛyera ne mu duru a ɛso tew mpofirim
• Ntini a ɛho ahonhon (ebetumi ada adi sɛ akuru wɔ mmeae te sɛ kɔn, abasa, ne asen) .

Fa no sɛ wo ba no nwiinwii wɔ yafunu mu yaw ho nna pii, sɛ ontumi nnidi, na ne ho fifiri retu no kɛse anadwo. Ebia wubesusuw sɛ eyi yɛ atiridiinini a ɔyare mmoawa de ba a ɛfata ara kwa. Nanso sɛ saa sɛnkyerɛnne ahorow yi mu yɛ den da biara da a, akyinnye biara nni ho sɛ ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn. Efisɛ Burkitt lymphoma akisikuru no betumi ayɛ kɛse mmɔho abien wɔ nna kakraa bi pɛ mu. Ɛno nti na ɛho hia sɛ yɛyɛ ho biribi ntɛm no.

Dɛn nti na saa yare yi ba? Dɛn na ɛde ba?

Nnuruyɛfo da so ara nnim nea ɛde Burkitt lymphoma ba ankasa. Nanso, wɔahu sɛ ɛne nsakrae a ɛba awosu mu abɔde bi a wɔfrɛ no MYC a ɛhwɛ yɛn nkwammoaa nyin so no wɔ abusuabɔ. Saa MYC awosu mu abɔde yi betumi ayɛ adwuma dodo esiane awosu mu sintɔ titiriw bi a wɔfrɛ no translocation nti .

Wɔ Sri Lanka, sɛnea ɛte wɔ aman afoforo so wɔ wiase nyinaa no, nnipa binom a wɔanya Epstein-Barr mmoawa (EBV) no nya Burkitt lymphoma. Nanso, ɛho hia sɛ yɛkae sɛ ɛnyɛ obiara a ɔwɔ EBV no na obenya saa kokoram yi.

Nsɛnnennen bɛn na ebetumi afi tebea yi mu aba?

Saa kokoram yi betumi de nsɛnnennen bi aba, a nea ɛka ho ne:

• Mogya mu nkwammoaa dodow a ɛso tew (nemia, mogya mu nkwammoaa fitaa dodow, mogya mu nkwammoaa dodow). Ebia eyi bɛhwehwɛ sɛ wɔde mogya ma.
• Tumor Lysis Syndrome : Eyi yɛ tebea a egye ntɛmpɛ a nipadua no mu nnuru a ɛkari pɛ no sɛe denam nneɛma a efi kokoram nkwammoaa mu bere a wowuwu ntɛmntɛm no so.
• Nkwammoaa a ɛko tia nyarewa a ɛyɛ mmerɛw (ɛnyɛ den sɛ ɔyare bɛba).

Sɛ ɛyɛ den ma wo anaa wo ba sɛ wubedi saa sɛnkyerɛnne ahorow yi so a, ka kyerɛ wo duruyɛfo ntɛm ara.

Ɔkwan bɛn so na nnuruyɛfo hu eyi pɛpɛɛpɛ?

Sɛnea ɛbɛyɛ na woahu no yiye sɛ wowɔ Burkitt Lymphoma no, ebia wo duruyɛfo no bedi kan ayɛ lymph node biopsy , a nea ɛka ho ne sɛ wobɛfa lymph node a ahonhon ketewaa bi na ɔde afiri a wɔde hwɛ nneɛma nketenkete ahwɛ.

Nea ɛka ho no, wobetumi ayɛ sɔhwɛ ahorow a edidi so yi:

• CT scan: Wɔde hwɛ sɛ akisikuru bi wɔ koko, yafunu, ne akyi berɛmo mu.
• PET scan: Saa scan yi twe adwene si nipadua no mmeae a kokoram wɔ so pɔtee.
• Bone marrow biopsy: Sɛnea ɛbɛyɛ a wobehu sɛ kokoram no atrɛw akɔ nnompe mu ntini no mu anaa.
• Lumbar puncture: Sɛnea ɛbɛyɛ a wɔbɛhwɛ sɛ kokoram nkwammoaa wɔ nsu a ɛwɔ akyi berɛmo no mu no mu.

Ɔkwan bɛn so na wohu kokoram no fã ahorow?

Nnuruyɛfo de saa akwan yi di dwuma de hu baabi a kokoram no atrɛw akodu:

• Ɔfã I (1): Kokoram no wɔ beae biako pɛ, anaasɛ ntini biako pɛ.
• Ɔfã II (2): Kokoram wɔ mmeae abien anaa nea ɛboro saa wɔ diaphragm , ntini a ɛboa yɛn ma yɛhome no fã koro.
• Ɔfã III (3): Kokoram wɔ ahurututu no afã abien no nyinaa.
• Ɔfã IV (4): Kokoram no atrɛw wɔ ntini a ɛma mogya tu no akyi, akɔ mmeae te sɛ mmerɛbo, ahurututu, ne nnompe mu ntini.

Dɛn ne ayaresa ahorow no?

Esiane sɛ Burkitt Lymphoma trɛw ntɛmntɛm nti, ɛsɛ sɛ wofi ase sa yare ntɛm ara sɛnea wobetumi. Ayaresa atitiriw a wobetumi apaw ne:

• Nnuru a wɔde sa yare: Eyi ne ayaresa titiriw. Mpɛn pii no, wɔde nnuru a ano yɛ den paa ma, na bere a wɔahu yare no ara pɛ na wofi ase.
• Nkwammoaa a ɛko tia nyarewa no ayaresa: Eyi yɛ adwuma denam boa a ɛboa wo nipadua no ankasa nipadua mu tumi a ɛko tia nyarewa no ma wohu kokoram nkwammoaa na ɛsɛe no so.
• Mframa a wɔde sa yare: Ɛtɔ mmere bi a wɔde di dwuma ne nnuru a wɔde sa yare, nanso wɔtaa de ma mpanyimfo.
• Stem cell transplant: Sɛ kokoram no san ba bere a wɔasa no yare awie a, eyi betumi aboa.
• Oprehyɛn: Wɔntaa mfa eyi nni dwuma. Sɛ nhwɛso no, wɔ nsɛm a akisikuru bi asiw dwensɔtwaa no kwan mu.

Bere bɛn na ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn?

Wo duruyɛfo bɛyɛ nhyehyɛe sɛ wobedi w’akyi de ahwɛ w’akwahosan. Saa mmere yi mu no, obetumi ayɛ mogya mu nhwehwɛmu ne CT scan nso.

Sɛ wo anaa wo ba wɔ saa sɛnkyerɛnne yi bi a, kɔ oduruyɛfo nkyɛn ntɛm ara :

• Koko mu yaw anaasɛ ɛyɛ den sɛ wobɛhome
• Sɛ atiridiinini no boro digrii Celsius 38 (100.4 Fahrenheit) a .
• Mogya a efi hwene mu anaasɛ mogya a ɛretu wɔ anom
• Ɛyaw a ɛba bere nyinaa
• Wora a ɛyɛ mmerɛw anaasɛ ɛnyɛ den sɛ ɛbɛpirapira

Nsɛm bɛn na ɛsɛ sɛ wubisa oduruyɛfo no?

Sɛ wuhu sɛ wo anaa wo ba wɔ Burkitt Lymphoma wie a, ebia wobɛpɛ sɛ wubisa wo duruyɛfo nsɛm te sɛ eyinom:

• Ɛhe na kokoram no wɔ?
• Ɔkwan bɛn so na eyi wɔ?
• Ayaresa bɛn na wokamfo kyerɛ?
• So me/me ba no betumi akɔ adwuma/sukuu?
• So ɛsɛ sɛ woyɛ sɔhwɛ pii?
• Dɛn na yebetumi ahwɛ kwan wɔ daakye (nsusuwii) ho?

Sɛ wunya Burkitt Lymphoma a, dɛn na wubetumi ahwɛ kwan?

Burkitt Lymphoma yɛ kokoram a wobetumi asa wɔ nsɛm dodow no ara mu.. Ɛyɛ n’ade yiye wɔ ayaresa ho, titiriw wɔ mmofra nkumaa ne mpanyimfo nkumaa mu. Mmofra tumi gyina nnuru a wɔde sa yare ano yiye sen mpanyimfo. Ebia mpanyimfo benya akwahosan ho haw afoforo, enti ebia ayaresa bɛyɛ den kakra.

Dɛn ne dodow a wɔn ho bɛtɔ wɔn?

Ɛwom sɛ Burkitt Lymphoma yɛ yare a emu yɛ den a ɛtrɛw ntɛmntɛm de, nanso nnipa dodow no ara yɛ wɔn ade yiye wɔ ayaresa ho. Sɛ wɔkyekyem pɛpɛɛpɛ a, nnipa dodow a wonya nkwa te sɛ nea edidi so yi:

• Mfiase: Mmofra bɛboro 90% ho tɔ wɔn wɔ bere tenten mu.
• Wɔ mmofra a wɔn mfe akɔ anim mu no: Wɔn mu 80% kosi 90% na wɔn ho tɔ wɔn.
• Mpanyimfo: Nsɛnkyerɛnne bɛboro 50% kɔ wɔ ayaresa akyi (`remission`).

Eyinom yɛ gyinapɛn ahorow a wɔkyekyem pɛpɛɛpɛ ara kwa. Ebia wo tebea no bɛyɛ soronko. Enti, wo ne wo duruyɛfo nkasa na woasua pii afa w’ankasa wo tebea no ho. Nsuro, ɛho hia paa sɛ wunya akokoduru.

Nneɛma bɛn na wubetumi ayɛ? (Afotu a ɛfa sɛnea wobɛhwɛ wɔn ho) .

Ayaresa bere no betumi ayɛ den kakra, nanso nneɛma bi wɔ hɔ a ebetumi aboa wo ma woagyina ano:

• Hwehwɛ mmoa: Sɛ wo ne nnipa a wɔafa osuahu a ɛte saa ara mu bɛkasa a, ebetumi ayɛ ahoɔden fibea kɛse. Mmoa akuw bi wɔ hɔ a nnipa te sɛ wo betumi anya mmoa.
• Gye w’ahome pii: Ma wo nipadua no bere ma ɛsa yare.
• Didi yiye: Hwehwɛ afotu fi aduan ho ɔbenfo hɔ na di nnuan a ɛbɛma wo nipadua anya ahoɔden bere a wɔreyɛ ayaresa no.
• Di kan yɛ nhyehyɛe: Bisa wo duruyɛfo nea wobɛhwɛ kwan.
• Nya mmoa fi w’adɔfo hɔ: Abusuafo ne nnamfo ayɛ krado sɛ wɔbɛboa wo.
• Boa wo ba: Nnuruyɛfo atitiriw bi wɔ hɔ a wobetumi aboa mmofra ma wɔadi yare yi fã a ɛfa nkate ho no ho dwuma (e.g., mmofra asetra ho ɔbenfo).

Nea etwa to no, nneɛma a ɛsɛ sɛ yɛkae

Ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ woayɛ basaa na woahaw bere a wuhu sɛ wo anaa wo ba wɔ Burkitt Lymphoma no. Ebia wowɔ nsɛmmisa ne ehu pii. Nanso ɛnyɛ wo nko ara.

Ɛwom sɛ kokoram yi trɛw ntɛmntɛm de, nanso ayaresa a wobetumi apaw no tu mpɔn yiye. W’aduruyɛfo kuw no befi ayaresa ase ntɛm na wɔaboa wo wɔ anammɔn biara a wobɛtu. Enti, ɛho hia paa sɛ wususuw nneɛma pa ho na wudi afotu a wo nnuruyɛfo de ma no akyi.

` Burkitt lymphoma, kokoram, mmofraberem kokoram, lymphoma, sɛnkyerɛnne, ayaresa, B nkwammoaa