Ebia wo duruyɛfo akyerɛw wo anaa w’abusua mu obi aduru bi a wɔfrɛ no Chlorpromazine. Sɛ wote saa din yi a, ebia wobɛte nka sɛ ehu aka wo kakra anaa wopɛ sɛ wuhu. Ɛyɛ ade a ɛfata sɛ wobisa nsɛm te sɛ, ‘Dɛn ne aduru yi? Dɛn nti na wɔde eyi rema me?’ sɛ ɛbɛba w’adwene mu. Esiane sɛ eyi yɛ aduru a wɔtaa de ma adwenemyare nti, adwene a ɛnteɛ ahorow betumi aba nkurɔfo mu. Enti ɛnnɛ, momma yɛnka chlorpromazine aduru yi ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw a wubetumi ate ase so.
Dɛn ankasa ne Chlorpromazine?
Sɛ yɛbɛka no tiawa a, chlorpromazine yɛ aduru a wɔde sa adwenemyare ahorow pii. Ɛka nnuru bi a wɔfrɛ no nnuru a ekum adwene mu yare ho . Dopamine yɛ nnuru bi a ɛwɔ amemene no mu a ɛboa ma yɛdi nneɛma te sɛ yɛn adwene ne yɛn nkate so. Saa aduru yi yɛ adwuma denam dopamine yi dodow a ɛkari pɛ wɔ amemene no mu no so.
Nanso, ɛnyɛ adwenemyare nko na wɔkyerɛw saa aduru yi ma. Nnuruyɛfo de di dwuma wɔ tebea afoforo pii mu. Nhwɛsoɔ:
- Adwene mu nyarewa te sɛ adwenemhaw ne adwenemhaw a ɛma obi yɛ ade tra so.
- Di akisikuru ne ɔfe so.
- Wɔ hiccups a akɔ so akyɛ na wontumi nsiw ano no nti.
- Wɔ yare a wɔfrɛ no porphyria no bi ho.
- Ma ntini ahorow no dwo bere a tetanus renya no.
- Ma ɔyarefo no dwo ansa na wɔayɛ no oprehyɛn anaa aduruyɛ mu nhwehwɛmu biara.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom saa aduru yi
Ansa na wubefi saa aduru yi ase no, ɛho hia yiye sɛ wode w’akwahosan ho nkyerɛkyerɛmu a edi mũ ma wo duruyɛfo. Efisɛ ɛsɛ sɛ wɔde ahwɛyiye de saa aduru yi di dwuma wɔ nnipa a wɔwɔ ayaresa tebea horow bi mu. Sɛ wowɔ tebea horow a wɔabobɔ din wɔ ase ha no bi a, hwɛ hu sɛ wobɛka ho asɛm akyerɛ wo duruyɛfo.
| Tebea/ntease a ɛfa ho | Nkyerɛmu |
|---|---|
| Ayaresa tebea horow a ɛwɔ hɔ dedaw | Amemene mu akisikuru, adwenemhaw, asikreyare, atiridiinini, ti a opira, komayare, abakɔsɛm a ɛkyerɛ sɛ koma bɔ ntɛmntɛm, asaabo anaa mmerɛbo mu yare, mogya mmoroso a ɛba fam, ahurututu mu yare te sɛ ayamtu, Parkinson yare, prostate yare, akisikuru. |
| Nipadua mu a ɛyɛ mmerɛw | Ɛyɛ den sɛ ɔbɛmene aduan, ɛyɛ den sɛ wobedi dwensɔtwaa so, ɛyɛ den sɛ wobɛtow nsu, ne dwensɔtwaa a ɛsiw. |
| Ɔhaw ahorow a ɛfa mogya ho | Tebea horow te sɛ mogya mu nkwammoaa fitaa a ɛba fam, mogya mu nkwammoaa kɔkɔɔ, anaa mogya mu nkwammoaa kɔkɔɔ. |
| Asetra kwan ne suban ahorow | Sɛ woyɛ obi a ɔtaa nom nsa a. |
| Nneɛma a ɛma obi ho yɛ no hyew | Sɛ wo ho yɛ wo hyew wɔ chlorpromazine, sulfites, nnuru afoforo, nnuan, nnuru a wɔde yɛ nneɛma anaa nneɛma a wɔde siesie nneɛma ho a. |
| Mmere titiriw | Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaa worema nufu a. |
Ɔkwan bɛn so na wɔde aduru yi ma?
Eyi nyɛ aduru a wubetumi de akɔ fie. Chlorpromazine yɛ aduru a wɔde twitwiw nipadua mu a oduruyɛfo bi de ma wɔ ayaresabea anaa ayaresabea . Wɔde ma nipadua no denam nea wɔde gu ntini bi mu anaasɛ wɔde gu ntini bi mu so.
Ɛsɛ sɛ wɔhwɛ yiye titiriw bere a wɔde aduru yi rema mmofra no. Ɛwom sɛ wɔkamfo kyerɛ wɔ nsɛm titiriw bi mu ma mmofra a wɔadi boro asram 6 de, nanso ɛho hia sɛ wodi ahwɛyiye a ɛfata akyi.
Overdose - Ɛho hia yiye!
Sɛ wususuw sɛ woanom aduru yi dodo a, mmu w’ani ngu so da. Kɔ ayaresabea Emergency Unit (ETU) ntɛm ara. Sɛ ɛho hia a, wubetumi afrɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ akɔhwehwɛ afotu.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Ɛho hia yiye sɛ woka nnuru a worenom nyinaa kyerɛ wo duruyɛfo, efisɛ chlorpromazine tumi ne nnuru afoforo pii di nkitaho.
| Mfa chlorpromazine nka eyinom ho da. | |
|---|---|
| Cisapride na ɔkyerɛwee | Pimozide a wɔde yɛ nnuru |
| Dronedarone a wɔfrɛ no Dronedarone | Saquinavir a wɔde di dwuma |
| Metoclopramide a wɔde di dwuma | Thioridazine a wɔde ma |
| Hwɛ yiye titiriw efisɛ ɔhaw ahorow betumi asɔre wɔ eyinom nso ho. | |
| Nsaden | Lithium a wɔde yɛ nneɛma |
| Nnuru a ekum akisikuru a wɔde sa akisikuru, ɔfe, ne atiridiinini | Nnuru a wɔde sa mogya mmoroso |
| Nnuru a wɔde sa adwennwen, dadwen, anaa nna | Nnuru a wɔde ko tia akisikuru (Phenobarbital, Phenytoin) . |
| Nnuru a wɔde sa Parkinson yare (Levodopa) . | Nnuru a wɔde yɛ nnubɔne |
| Nnuru a wɔde ma obi da bere a wɔreyɛ oprehyɛn no | Nnuru a ɛma mogya yɛ mmerɛw te sɛ Warfarin |
Saa nsɛm a wɔahyehyɛ yi nwiei, enti hwɛ hu sɛ wobɛka nnuru, vitamin, anaa aduru biara a worenom ho asɛm akyerɛ wo duruyɛfo.
Nneɛma a ɛsɛ sɛ wususuw ho bere a worenom nnuru no
W’aduruyɛ kuw no bɛhwɛ wo tebea no yiye bere a worenya saa aduru yi, nanso ɛho hia sɛ wuhu saa nokwasɛm ahorow yi.
Dae a obi da ne adwenemhaw
Ebia saa aduru yi bɛma woate nka sɛ woada, wo ti ayɛ wo yaw, anaasɛ w’ani nhu ade yiye . Enti kwati nneɛma a asiane wom te sɛ karka anaa mfiri a wode bedi dwuma kosi sɛ wubehu sɛnea aduru yi ka wo. Hwɛ yiye bere a woresɔre anaa wotena ase mpofirim no , titiriw sɛ woabɔ akwakoraa a. Eyi betumi atew hokwan a ɛwɔ hɔ sɛ obi bɛtotɔ piti na wahwe ase no so. Nsã a wɔnom betumi ama saa nna yi asɛe kɛse.
Nipadua mu hyew a wɔhwɛ so
Saa aduru yi betumi aka sɛnea wo nipadua no tumi hwɛ ɔhyew so. Ebia wim tebea a ɛyɛ nwini a wutumi gyina ano no so bɛtew, na ɔhyew a wutumi gyina ano no so bɛtew. Enti, hyɛ ntade a ɛyɛ hyew wɔ nna a awɔw wom. Nna a ɛyɛ hyew no, to owia a wobɛkɔ so, apɔw-mu-teɛteɛ, na nom nsu pii ano hye.
Owia ho nkate a ɛma obi te nka
Ebia saa aduru yi bɛma wo honam ani ayɛ mmerɛw wɔ owia ho. Enti bɔ wo ho ban fi owia ho. Sɛ ɛsɛ sɛ wupue kɔ owia mu a, hyɛ ntade a ɛkata wo nipadua so na fa aduru a ɛbɔ wo ho ban fi owia ho di dwuma .
Ano a ɛyɛ nwunu
Ano a ɛyɛ mmerɛw yɛ ade a ɛtaa ba wɔ aduru yi mu. Wobetumi adi eyi ho dwuma denam anom a asikre nnim a wɔbɛwe, ahwiesa a wɔannom, ne nsu pii a wɔbɛnom so.
Dɛn ne nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ aduru biara no, chlorpromazine betumi anya nkɛntɛnso bɔne. Ebi yɛ aniberesɛm, ebi nso abu so. Ɛho hia sɛ wohu eyinom.
| Nneɛma bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo anaa ayaresabea amanneɛ ntɛm ara | |
|---|---|
| Nneɛma a ɛma obi ho yɛ no hyew | Honam ani akisikuru, ɛyaw, anim, anofafa, tɛkrɛma anaa menewa a ɛho ahonhon. |
| Neuroleptic Malignant Syndrome a Ɛyɛ Fɛ a Ɛyɛ Fɛ | Atiridiinini a ano yɛ den mpofirim, ntini a ɛyɛ den, fifiri a ɛboro so, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ, adwene a ɛyɛ basaa. |
| EPS ho sɛnkyerɛnne (Extrapyramidal Nsɛnkyerɛnne) . | Nipadua akwaa a wontumi nhyɛ so (titiriw anim, ano), ntini a ɛyɛ den, wosow, kari pɛ a ɛnkari pɛ, ahomegye a enni hɔ. |
| Mmerɛbo a ɛsɛe | Ɛyaw a ɛba yafunu nifa so atifi, aduan ho akɔnnɔ a ɛyera, akisikuru, honam ani anaa aniwa a ɛyɛ kɔkɔɔ, nsu a ɛyɛ kɔkɔɔ/biribiri tuntum, ne nsu a ɛyɛ kɔla a ɛyɛ hann. |
| Nsɛnkyerɛnne afoforo a anibere wom | Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare mmoawa (atiridiinini, atiridiinini, ɔfe, menewa mu yaw), mogya mmoroso a ɛba fam (atiridiinini, akisikuru). |
| Nneɛma a mpɛn pii no ɛnyɛ aniberesɛm, nanso sɛ ɛkɔ so a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo | |
| Ayamtim | Ano a ɛyɛ nwunu |
| Dae a ɛma obi da | Mu duru a ɛkɔ soro |
| Adwene a ɛyɛ basaa | |
Sɛ wuhu sɛnkyerɛnne foforo biara a ɛyɛ soronko a wɔanka ho asɛm wɔ saa nsɛm yi mu a, wo ne wo duruyɛfo nkasa mfa ho nso.
Nkrasɛm a Wɔde Kɔ Fie
- Chlorpromazine yɛ aduru a wɔde bɔ nkurɔfo ho ban a wɔde ma wɔ ayaresabea anaa ayaresabea nkutoo wɔ oduruyɛfo hwɛ ase.
- Hwɛ hu sɛ wobɛka nnuru afoforo a wonom nyinaa, aduruyɛ mu tebea foforo biara a wowɔ, ne nneɛma biara a ɛma wo ho yɛ wo hyew ho asɛm akyerɛ wo duruyɛfo.
- Hwɛ yiye bere a woreyɛ nnwuma a ɛhwehwɛ sɛ woma w’ani da hɔ, te sɛ karka, efisɛ ebia nna ne adwenemhaw betumi aba bere a worenom aduru no. Kwati nsa a wobɛnom.
- Sɛ wunya ɔhaw biara a emu yɛ den te sɛ atiridiinini a ano yɛ den, ntini a ɛyɛ den, nipadua a ɛkeka ne ho a wuntumi nni so, anaa honam ani a ɛyɛ kɔkɔɔ a, hwehwɛ aduruyɛfo afotu ntɛm ara.
- Sɛ wowɔ aduru yi ho dadwen anaa ehu bi a, wo ne wo duruyɛfo nka ho asɛm pefee.
👩🏽 ⚕️ Nsɛmmisa foforo (FAQs)
💬 Chlorpromazine Injection / Thorazine yɛ aduru a ano yɛ den paa a wɔde sa yareɛ bɛn?
Eyi nyɛ aduru a wɔde di dwuma ɔkwammɔne so! Eyi yɛ aduru a egye ntɛmpɛ a akyɛ sen biara na tumi wom sen biara (First-Generation Antipsychotic) a wɔde ma ɔyarefo no dwo ntɛm ara na wɔde no da kɛse (a ɛma ɔda no dwo) wɔ nsɛm a ‘adwene mu abɔdamfo’ a emu yɛ den (Severe Psychosis/Agitation) a adwenemhaw, adwenemhaw a ɛma obi yɛ ade tra so, ne nnuru de ba no mu, bere a ɔyarefo no ayɛ basaa a ontumi nni so, na ɔyɛ wɔ asiane kɛse mu sɛ obepira afoforo anaa n’ankasa ho.
💬 Sɛ woreteɛteɛm/woreteɛteɛm te sɛ ɔkraman a, ɔkwan bɛn so na saa injection (Chlorpromazine) yi boa w’amemene no yare/da?
Wohu/ɛhaw nneɛma a ɛte saa a ɛyɛ nwonwa kɛse bere a nnuru ‘Dopamine (Dopamine / D2)’ a ɛwɔ amemene no mu no boro so no! Saa vaccine yi siw/to mu koraa na ɛto ‘Dopamine receptors’ a ɛwɔ amemene no mu nyinaa (Dopamine antagonist). Bio nso, ɛsan dum mfiri ahorow no wɔ ‘Histamine (H1)’ ne ‘Adrenaline (Alpha-1)’ fã no mu, enti ɔyarefo no yɛ komm na ɔtra ase dinn/da wɔ simma kakraa bi mu.
💬 Dɛn ne nsunsuanso bɔne a ebetumi akum obi (Black Box Warnings) a ɛwɔ saa vaccine (Thorazine) a ɛsɛe amemene kɛse yi mu?
Asiane kɛse ne sɛ, sɛ wɔde eyi ma wɔn a wɔn mfe akɔ anim a wɔwɔ adwenemhaw (Dementia-related psychosis) a, wobetumi agyae ahome mpofirim na wɔawuwu (Increased mortality)! Adeɛ foforɔ a ɛyɛ hu paa ne sɛ yei bɛtumi ama ɔyarefoɔ no atɔ coma mu ɛnam ‘Fatal Hypotension / Orthostatic’ nti. Afei nso, ntini mu yare a emu yɛ den a ɛmma wontumi ntra hɔ dinn, na ɛma akwaa no wosow te sɛ ɔkraman na kɔn/aniwa no tu (Extrapyramidal Symptoms / EPS / Tardive Dyskinesia) betumi aba ampa.
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