Akwankyerɛ a Ɛyɛ Mmerewa a Ɛfa Nkwammoaa a Ɛnyɛ Nea Ɛtaa Yɛ a Ɛwɔ Abasa ne Nan Ho: Nea Ɛsɛ sɛ Wuhu Fa Clear Cell Sarcoma Ho | Nirogi Lanka na ɔkyerɛwee

So woahyɛ akuru anaa ade bi a ɛyɛ soronko wɔ wo nsa anaa wo nan ho were ase a ɛrenkɔ kɛkɛ no nsow? Ebia wubehu sɛ sɛ woka wo a, ɛmma wo yaw biara, nanso sɛ wote nka sɛ ɛrenyin nkakrankakra a, ɛho hia sɛ wohwɛ yiye. Ɛnnɛ, wɔ Nirogi Lanka , yɛpɛ sɛ yɛka kokoram bi a ɛntaa nsi nanso ɛho hia a ebetumi de saa sɛnkyerɛnne ahorow yi aba pɛpɛɛpɛ ho asɛm. Ɛyɛ tebea bi a wɔfrɛ no Clear Cell Sarcoma , na yegye di sɛ ɛho hia sɛ wunya ho nsɛm yiye.

Dɛn ne Clear Cell Sarcoma?

Sɛ yɛbɛka no tiawa a, Clear Cell Sarcoma yɛ kokoram a ɛntaa nsi koraa a efi wo nipadua mu ntini a ɛyɛ mmerɛw no mu. Ɛyɛ sarcoma abusua no dea. Saa akisikuru yi taa ba wo nan mu, titiriw wɔ baabi a ɛbɛn ntini —ntini a ɛyɛ den a ɛka wo ntini ne wo nnompe —ne ntini a ɛyɛ mmerɛw a atwa wo ntini ho ahyia no.

Te sɛ kokoram ahorow afoforo pii no, sɛ wuhu ntɛm a, ɛyɛ ade titiriw a ɛbɛma woanya ayaresa no yiye ansa na atrɛw akɔ wo nipadua no afã afoforo. Nnuruyɛfo taa de oprehyɛn , a mpɛn pii no wɔde mframa a wɔde sa yare ne, wɔ tebea horow bi mu no, nnuru a wɔde sa yare ka ho di tebea yi ho dwuma . Nea ɛyɛ awerɛhow no, kokoram a ɛte sɛɛ no ​​tumi san ba bio bere a wɔasa no yare mpo akyi. Esiane eyi nti, aduruyɛ mu nhwehwɛmufo a wɔwɔ Nirogi Lanka ne wiase nyinaa reyɛ adwuma bere nyinaa de ahu ayaresa akwan a etu mpɔn kɛse.

Ɔkwan bɛn so na Clear Cell Sarcoma ka wo nipadua?

Clear Cell Sarcoma taa fi ase wɔ ntini a ɛyɛ mmerɛw a ɛbɛn wo ntini , ntini, anaa fascia no mu tɔnn —ntini a ɛyɛ tratraa a ɛyɛ den a ɛka bom a ɛyɛ adwuma te sɛ ade a ɛboa a ɛkata wo ntini ne wo nhyehyɛe ahorow ho.

Mfiase no, ebia worenhu yare no ho sɛnkyerɛnne biara. Nanso, bere a akisikuru no nyin no, ebia wobɛte nka sɛ akisikuru a ɛyɛ den wɔ wo nan anaa wo nan ho were no ase pɛɛ. Bere a eyi betumi ayɛ te sɛ nea ɛyɛ akuturuku a efi opira dedaw bi mu no, nsonsonoe titiriw no ne sɛ bere kɔ so no, saa akisikuru yi nyera . Clear Cell Sarcoma taa nyin brɛoo paa, nanso bere a ɛbɛyɛ nea wotumi de wɔn nsa ka wɔ wo honam ani no, ebia na afi ase retrɛw akɔ nipadua no mmeae afoforo dedaw.

Sɛ wuhu sɛ akuru bi wɔ wo nan so na woka kyerɛ wo ho sɛ, "Ebia ɛyɛ opira ara kwa" a, yɛsrɛ wo yɛ ahwɛyiye. Sɛ saa akuru no kɔ so adapɛn anaa asram pii—anaasɛ efi ase nyin—ntwɛn. Hwehwɛ aduruyɛ mu afotu fi w’akwahosan ho ɔyaresafo hɔ ntɛm ara.

Ɛhe na Clear Cell Sarcoma betumi atrɛw?

Clear Cell Sarcoma betumi akɔ nipadua no afã afoforo, nea ɛda nsow kɛse ne:

• Wo yafunu mu ntini
• W’ahurututu
• Wo lymphatic system , a wo lymph nodes ne lymph vessels ka ho.

So eyi yɛ tebea a abu so?

Dabi, ɛho yɛ na koraa. Sarcomas mpo sɛ kuw no ntaa mma. Sɛ nhwɛso no, wɔ United States no, nnipa foforo bɛyɛ 1,600 na wohu sɛ wɔwɔ ntini a ɛyɛ mmerɛw sarcoma afe biara, na ɛyɛ mpanyimfo kokoram a wohu nyinaa mu bɛyɛ 1% pɛ. Clear Cell Sarcoma gyina hɔ ma saa nsɛm a wɔntaa nhu no mu bɛyɛ 1% pɛ. Eyi si sɛnea tebea yi nyɛ nea ɛtaa ba ankasa so dua.

Hena na ɔwɔ asiane mu kɛse?

Bere a Clear Cell Sarcoma betumi aba wɔ mfe biara mu no, wɔtaa hu no wɔ mmerante ne mmabaa a wɔadu mpanyin afe so a wɔadi fi mfe 15 kosi 40 mu , na ɛdɔɔso sen biara wɔ wo mfe 20 ne 30 mu.

Dɛn ne sɛnkyerɛnne ahorow no?

Sɛnea yɛaka no, sɛnkyerɛnne a ɛtaa ba ne akisikuru a ɛyɛ den na ɛkɔ so tra hɔ wɔ wo nan anaa wo nan honam ani. Ebia saa akuru yi bɛyɛ yaw anaasɛ ɛrenyɛ yaw. Nanso, sɛ ɛkɔ so tra hɔ na ɛte sɛ nea ɛrenyin a, ɛno ne kɔkɔbɔ sɛnkyerɛnne titiriw.

Wɔ akyiri yi mmere mu no, wubetumi nso ahu:

• Ɔbrɛ a ɛkɔ so daa, a wontumi nkyerɛkyerɛ mu
• Mu duru a ɛso tew a wontumi nkyerɛkyerɛ mu
• Anadwo fifiri a ɛba

Dɛn na ɛde Clear Cell Sarcoma ba?

Nea ɛde ba ankasa no yɛ nea emu yɛ den. Aduruyɛ mu nhwehwɛmu ada no adi sɛ Clear Cell Sarcoma fi awosu mu mfomso bi a ɛma nkwaboaa abien afã horow sesa mmeae, na ɛde awosu mu nkwaadɔm a wɔaka abom ba .

Ne titiriw no, bere a nkwammoaa mu mpaapaemu no, chromosomes tumi bubu na ɛsesa afã horow. Ne titiriw no, wɔsesa afã horow a EWSR1 ne ATF1 awosu mu nkwaadɔm wom. Mpɛn pii no, EWSR1 awosu mu abɔde no de ne ho hyɛ nkwammoaa mu nhyehyɛe mu, bere a ATF1 boa ma wɔhwɛ nkwammoaa nyin so. Sɛ saa chromosomes yi san bata ho a, wɔde awosu mu nneɛma a wɔaka abom no si hɔ wɔ ɔkwan a ɛnteɛ so. Nnuruyɛfo frɛ eyi sɛ ade foforo a wɔde kɔ baabi foforo . Nea enti a mfomso yi ba ara kwa no da so ara yɛ asɛm a nyansahu mu nhwehwɛmu kɔ so.

Sɛ nsakrae a ɛkɔ chromosome foforo mu yi ba pɛ a, awosu mu nkwaadɔm a wɔasan asiesie no bom yɛ awosu mu abɔde a wɔaka abom a wɔfrɛ no EWSR1/ATF1 . Nhwehwɛmufo gye di sɛ saa awosu mu abɔde pɔtee a wɔaka abom yi ne ade titiriw a ɛma nkwammoaa a emu da hɔ sarcoma ba.

Ɔkwan bɛn so na nnuruyɛfo hu nkwammoaa a emu da hɔ sarcoma?

Sɛ wokɔ wo duruyɛfo nkyɛn a akuru bi a ɛda adi wɔ hɔ a, wɔbɛyɛ nipadua mu nhwehwɛmu de ahwɛ beae a ɛwɔ, ne kɛse, ne ne su. Ebia wɔbɛkra nso sɛ wɔnyɛ MRI (Magnetic Resonance Imaging) scan na ama wɔahwɛ no yiye.

Nanso, wɔfa biopsy , a wogye ntini ketewaa bi fi akuru no mu si so dua sɛ wobetumi ahu nkwammoaa a emu da hɔ sarcoma no pɛpɛɛpɛ . Nyarewa ho animdefo—abenfo a wɔhwehwɛ ntini mu wɔ aduruyɛdan mu—bɛhwehwɛ nhwɛsode yi mu wɔ afiri a wɔde hwɛ nneɛma nketenkete mu ahwehwɛ EWSR1/ATF1 fused gene a yɛadi kan aka ho asɛm no pɔtee.

Ɔkwan bɛn so na wɔsa nkwammoaa a emu da hɔ sarcoma?

Wo nnuruyɛfo kuw no botae titiriw ne sɛ wobesiw kokoram no ano na antrɛw akɔ wo nipadua no afã afoforo. Mpɛn pii no, ade a edi kan ne oprehyɛn a wɔde yi akisikuru no nyinaa . Sɛ adanse wɔ hɔ a ɛkyerɛ sɛ kokoram no adu ntini a ɛbɛn hɔ a, wobeyi eyinom nso afi hɔ. Mpɛn pii no, wɔde aduru a ɛboa , a mpɛn pii no wɔde mframa a wɔde sa yare , di eyi akyi de sɛe kokoram nkwammoaa biara a aka.

Nhwehwɛmufo a wɔwɔ Nirogi Lanka ne akyirikyiri de nsiyɛ rehwehwɛ akwan foforo a wɔfa so sa yare no mu. Sɛ nhwɛso no, wɔresusuw sɛnea nipadua no mu tumi a ɛko tia nyarewa no yɛ adwuma yiye no howɔ nkwammoaa a emu da hɔ sarcoma a wɔhwɛ so mu. Bio nso, nnuruyɛ mu sɔhwɛ ahorow reyɛ nhwehwɛmu sɛ ebia nnuru a wɔde di dwuma mprempren ma kokoram ahorow afoforo betumi aboa ma wɔagyae tebea yi a ɛkɔ so no anaa.

Ɛho hia sɛ yɛte ase sɛ nkwammoaa mu sarcoma a emu da hɔ no wɔ su a ɛsan ba bio. Sɛ eyi ba a, ebia ɛho behia sɛ wɔyɛ oprehyɛn foforo anaa mframa a wɔde sa yare. Esiane sɛ kokoram a ɛte sɛɛ betumi atrɛw ntɛmntɛm nti, wo nnuruyɛfo bɛyɛ nhyehyɛe akɔhwɛ wo daa akɔhwɛ wo yiye sɛ ebia akisikuru foforo biara nyin anaa.

So metumi atew asiane a ɛwɔ hɔ sɛ menya nkwammoaa a emu da hɔ sarcoma no so?

Nea ɛyɛ awerɛhow no, ɔkwan biara nni hɔ a wonim a wɔbɛfa so atew asiane a ɛwɔ hɔ sɛ obi benya saa tebea yi so. Mprempren, nhwehwɛmufo ntumi nhu nneɛma pɔtee bi a ɛde asiane ba —su anaa tebea horow a ɛma yare no a ebetumi aba no yɛ kɛse —ma nkwammoaa mu sarcoma a emu da hɔ.

So wobetumi asa nkwammoaa a emu da hɔ sarcoma koraa?

Bere a nnuruyɛfo betumi asa nkwammoaa a emu da hɔ sarcoma denam akisikuru a woyi fi hɔ na wɔhwɛ sɛnea ɛtrɛw so no, mprempren wonsusuw sɛ ɛyɛ tebea a wobetumi asa koraa . Mpɛn pii no, ebedu bere a wobehu kokoram no, ebia na atrɛw akɔ nipadua no afã afoforo dedaw, na ama ayaresa no ayɛ den kɛse. Bio nso, sɛnea ɛbɛyɛ yiye sɛ ɛbɛsan aba bio no da so ara yɛ ade titiriw a ɛhaw adwene.

Nkwa nna bɛn na obi a ɔwɔ cell sarcoma a emu da hɔ betumi adi?

Nkwa nna yɛ akontaabu a egyina nnipa dodow ho nsɛm so, a wosusuw w’akwahosan nyinaa ne ankorankoro tebea horow ho. Nhwehwɛmu bi a US National Cancer Database yɛe wɔ afe 2018 mu no kyerɛe sɛ ankorankoro a wohui sɛ wɔwɔ clear cell sarcoma no mu 50% da so te ase wɔ mfe anum akyi , na 38% da so te ase wɔ mfe du akyi .

Bere a yɛreka nkwagye ho akontaabu ho asɛm no, ɛho hia sɛ yɛkae sɛ eyinom yɛ akontaabu ara kwa, na ɛnyɛ nkɔmhyɛ ahorow a ɛfa w’asɛm pɔtee no ho. Nnipa akuw akɛse so na ɛma wonya nkwa; nneɛma pii nya nea ebefi ankorankoro bi mu so nkɛntɛnso. Sɛ wɔahu sɛ wowɔ clear cell sarcoma a, wo duruyɛfo ne nea eye sen biara a obenya nsɛm a ɛfa wo nkɔmhyɛ pɔtee ne nea wohwɛ kwan ho.

So nkwammoaa a emu da hɔ sarcoma betumi akum obi?

Yiw, ebetumi akum nnipa. Mpɛn pii no, ankorankoro a wɔn kokoram atrɛw akɔ nipadua no afã afoforo no hyia nkɔmhyɛ a anibere wom sen wɔn a wɔsa wɔn yare ansa na kokoram no akɔ mmeae afoforo no.

Bere bɛn na ɛsɛ sɛ mekɔ me duruyɛfo nkyɛn?

Esiane sɛ Clear Cell Sarcoma wɔ asiane sɛ ɛbɛsan aba bio wɔ ayaresa akyi mpo nti, ebia wo duruyɛfo bɛhwehwɛ sɛ wokɔ hɔ asram abiɛsa biara wɔ mfe abien a edi kan wɔ w’ayaresa a edi kan no akyi, a egyina wo tebea pɔtee no so. Ɛda so ara ho hia sɛ wotoa saa bere a wɔahyɛ sɛ wobɛkɔ akɔhwɛ wo yi so wɔ saa bere no akyi mpo.

Nsɛm bɛn na ɛsɛ sɛ mibisa me duruyɛfo?

Clear Cell Sarcoma yɛ tebea soronko a ɛntaa nsi a ebetumi de nkwa ato asiane mu. Sɛ wɔahu sɛ wowɔ saa tebea yi a, nsɛmmisa bi a ebia wobɛpɛ sɛ wubisa w’akwahosan ho ɔyaresafo ni:

• Ɛhe na akisikuru no wɔ, na ne kɛse te dɛn?
• So akisikuru no atrɛw akɔ me nipadua no afã foforo biara?
• Ayaresa nhyehyɛe bɛn na wokamfo kyerɛ me?
• Dɛn ne ayaresa ahorow a wɔkamfo kyerɛ no mu nsunsuanso bɔne a ebetumi afi mu aba?
• Sɛ wɔyɛ me oprehyɛn a, asiane bɛn na ɛwɔ hɔ sɛ akisikuru no bɛsan aba?
• So nnuruyɛ mu sɔhwɛ ahorow bi wɔ hɔ a ɛsɛ sɛ misusuw ho?

Nsɛm a Wɔaboaboa Ano ne Nkrasɛm a Wɔde Kɔ Fie

Clear Cell Sarcoma yɛ yare a ɛyɛ den, a wɔntaa nhu a ɛka ankorankoro kakraa bi pɛ afe biara. Ɛtaa nyin nkakrankakra, na ebetumi ama tebea bi aba a kokoram no atrɛw dedaw bere a wubehu nipadua mu nsakrae biara no.

Nanso, yɛsrɛ sɛ kae sɛ nnuruyɛfo ayɛ nhyehyɛe ahorow a wɔde bedi Clear Cell Sarcoma ho dwuma na wɔasa, na mpɛn pii no ɛfa oprehyɛn a wɔyɛ de yi akisikuru no na wɔde ayaresa a ɛboa ma woyi kokoram nkwammoaa a aka no di akyi. Nea ɛyɛ awerɛhow no, asiane wɔ hɔ sɛ ɛbɛsan aba bio. Enti, wo bere a wobɛkɔ akɔhwɛ wo akyi na woama w’ani ada hɔ wɔ nsakrae biara a ɛbɛba wo nipadua mu ho no ho hia sen biara.

Nhwehwɛmufo reyɛ adwuma bere nyinaa de ayɛ ayaresa foforo a wɔatu mpɔn. Sɛ wohu sɛ wowɔ Clear Cell Sarcoma na w’ani gye ho sɛ wubesua nnuruyɛ mu sɔhwɛ foforo ho ade a , yɛsrɛ wo kɔ wo duruyɛfo nkyɛn kɔhwehwɛ akwankyerɛ. Mma anidasoɔ nsɛe da.Sɛ wonya aduruyɛ mu afotu a ɛfata, adwumayɛfo mmoa, ne ɔkwan a wɔfa so yɛ ade ntɛm a, wubetumi adi asɛnnennen yi ho dwuma yiye. Sɛ wuhyia ntɛmpɛ a, yɛsrɛ wo, frɛ 911 anaa kɔ dwumadibea a ɛbɛn wo a wɔhwɛ ntɛmpɛ so ntɛm ara.

Nirogi Lanka: nkwammoaa a emu da hɔ sarcoma, ntini a ɛyɛ mmerɛw kokoram, nan mu akisikuru, nan mu akisikuru, sarcoma, kokoram ho sɛnkyerɛnne, kokoram ayaresa